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The map label for this gene is insK [C]

Identifier: 117920570

GI number: 117920570

Start: 2551189

End: 2551911

Strand: Reverse

Name: insK [C]

Synonym: Shewana3_2126

Alternate gene names: 117920570

Gene position: 2551911-2551189 (Counterclockwise)

Preceding gene: 117920571

Following gene: 117920569

Centisome position: 51.32

GC content: 47.44

Gene sequence:

>723_bases
GTGGTGCAAACGGTACAATATGAACGGTTATTTCAACCGCGAGTCGGTACGCGTAAACTGCAGTATTTACTCAACAAAAT
GCATCAAATAGTGATAGGACGAGACCGGTTATTTCGCTGTCTTAGGGCGCATCGTTTGTTGGTCACGCCGAAACGGGCGT
ACCATAAAACGACCCATAGCCATCATCGATTTAGGTGTCATCCCAACTTGCTTAAGCCCAGTGAGCAGCAAGTGGACATC
AGCCGCTCAGAACAAGTCTGGGTGGCTGATATTACCTATCTGTCACTGCAAGATAATGAAGCCTATTTAAGCTTGGTGAC
CGATGCCTGGTCACGAAAAATTGTGGGTTATCATGTTGATGATAATCTTAAAACAGACGGGGTGCTAACGGCTTACAAAC
GGGCACTGAGACAGCGACAAGATAAAAGTAAACCGCTGATACACCACTCAGACCGAGGGATACAGTACTGCTCAAACGCG
TATCAAGCGGTTCACGCACAACATGGCGTGACATGCTCAATGACAGACGGATATGACTGCTATCAAAATGCCTTAGCAGA
GCGAGTGAATGGCATCTTGAAGCAGGAGTTTTTAACACATAAGCCCGCAACGCTGGAGGAGGCGCGACAAATGGTGGCAG
AAGCGGTTGCCATCTATAATCAACGACGGCCACATTTGGCCTTAAAATACAAAACGCCCGATGAGGTTCATCGAGCGTTT
TAG

Upstream 100 bases:

>100_bases
TTATGGCGTCACCCAATGCTGTCGTTACCTTGGCATCAGTCGCCAGGCGTATTATCAACAATGCCAGCGGCAAATCGTCT
CAGAGCTAAAGGAGCAAGAG

Downstream 100 bases:

>100_bases
GTGGAAATAAGTGTCAACTTATTTCAGGACGAGACATAGCAAAGCGTAGGTGAGTTCACTCATTGCGCTGTGTTCATGCA
ATTTTGTATAAGATAACCAT

Product: integrase catalytic subunit

Products: NA

Alternate protein names: ISO-S3 31 kDa protein [H]

Number of amino acids: Translated: 240; Mature: 240

Protein sequence:

>240_residues
MVQTVQYERLFQPRVGTRKLQYLLNKMHQIVIGRDRLFRCLRAHRLLVTPKRAYHKTTHSHHRFRCHPNLLKPSEQQVDI
SRSEQVWVADITYLSLQDNEAYLSLVTDAWSRKIVGYHVDDNLKTDGVLTAYKRALRQRQDKSKPLIHHSDRGIQYCSNA
YQAVHAQHGVTCSMTDGYDCYQNALAERVNGILKQEFLTHKPATLEEARQMVAEAVAIYNQRRPHLALKYKTPDEVHRAF

Sequences:

>Translated_240_residues
MVQTVQYERLFQPRVGTRKLQYLLNKMHQIVIGRDRLFRCLRAHRLLVTPKRAYHKTTHSHHRFRCHPNLLKPSEQQVDI
SRSEQVWVADITYLSLQDNEAYLSLVTDAWSRKIVGYHVDDNLKTDGVLTAYKRALRQRQDKSKPLIHHSDRGIQYCSNA
YQAVHAQHGVTCSMTDGYDCYQNALAERVNGILKQEFLTHKPATLEEARQMVAEAVAIYNQRRPHLALKYKTPDEVHRAF
>Mature_240_residues
MVQTVQYERLFQPRVGTRKLQYLLNKMHQIVIGRDRLFRCLRAHRLLVTPKRAYHKTTHSHHRFRCHPNLLKPSEQQVDI
SRSEQVWVADITYLSLQDNEAYLSLVTDAWSRKIVGYHVDDNLKTDGVLTAYKRALRQRQDKSKPLIHHSDRGIQYCSNA
YQAVHAQHGVTCSMTDGYDCYQNALAERVNGILKQEFLTHKPATLEEARQMVAEAVAIYNQRRPHLALKYKTPDEVHRAF

Specific function: Involved in the transposition of the insertion sequence is150 [C]

COG id: COG2801

COG function: function code L; Transposase and inactivated derivatives

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 integrase catalytic domain [H]

Homologues:

Organism=Homo sapiens, GI310129419, Length=201, Percent_Identity=32.8358208955224, Blast_Score=88, Evalue=6e-18,
Organism=Escherichia coli, GI1789981, Length=169, Percent_Identity=30.1775147928994, Blast_Score=84, Evalue=7e-18,
Organism=Escherichia coli, GI1788405, Length=158, Percent_Identity=33.5443037974684, Blast_Score=83, Evalue=1e-17,
Organism=Escherichia coli, GI1787263, Length=158, Percent_Identity=33.5443037974684, Blast_Score=83, Evalue=1e-17,
Organism=Escherichia coli, GI1786753, Length=158, Percent_Identity=33.5443037974684, Blast_Score=83, Evalue=1e-17,
Organism=Escherichia coli, GI1786570, Length=158, Percent_Identity=33.5443037974684, Blast_Score=83, Evalue=1e-17,
Organism=Escherichia coli, GI1786490, Length=158, Percent_Identity=33.5443037974684, Blast_Score=83, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001584
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00665 rve [H]

EC number: NA

Molecular weight: Translated: 28058; Mature: 28058

Theoretical pI: Translated: 9.95; Mature: 9.95

Prosite motif: PS50994 INTEGRASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVQTVQYERLFQPRVGTRKLQYLLNKMHQIVIGRDRLFRCLRAHRLLVTPKRAYHKTTHS
CCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHEECCHHHHHHCCCC
HHRFRCHPNLLKPSEQQVDISRSEQVWVADITYLSLQDNEAYLSLVTDAWSRKIVGYHVD
CCEEEECCCCCCCCCHHCCCCCCCEEEEEEEEEEEEECCCHHHHHHHHHHHCCEEEEECC
DNLKTDGVLTAYKRALRQRQDKSKPLIHHSDRGIQYCSNAYQAVHAQHGVTCSMTDGYDC
CCCCCCHHHHHHHHHHHHHHHCCCCCEEECCCHHHHHHHHHHHHHHHCCCEEECCCCHHH
YQNALAERVNGILKQEFLTHKPATLEEARQMVAEAVAIYNQRRPHLALKYKTPDEVHRAF
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEECCHHHHHHCC
>Mature Secondary Structure
MVQTVQYERLFQPRVGTRKLQYLLNKMHQIVIGRDRLFRCLRAHRLLVTPKRAYHKTTHS
CCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHEECCHHHHHHCCCC
HHRFRCHPNLLKPSEQQVDISRSEQVWVADITYLSLQDNEAYLSLVTDAWSRKIVGYHVD
CCEEEECCCCCCCCCHHCCCCCCCEEEEEEEEEEEEECCCHHHHHHHHHHHCCEEEEECC
DNLKTDGVLTAYKRALRQRQDKSKPLIHHSDRGIQYCSNAYQAVHAQHGVTCSMTDGYDC
CCCCCCHHHHHHHHHHHHHHHCCCCCEEECCCHHHHHHHHHHHHHHHCCCEEECCCCHHH
YQNALAERVNGILKQEFLTHKPATLEEARQMVAEAVAIYNQRRPHLALKYKTPDEVHRAF
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEECCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2824781 [H]