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The map label for this gene is eco [H]

Identifier: 117920445

GI number: 117920445

Start: 2385005

End: 2385556

Strand: Reverse

Name: eco [H]

Synonym: Shewana3_2000

Alternate gene names: 117920445

Gene position: 2385556-2385005 (Counterclockwise)

Preceding gene: 117920447

Following gene: 117920441

Centisome position: 47.98

GC content: 44.02

Gene sequence:

>552_bases
ATGAAATTGACTCACTTATTTAACACTGCGGCACTTCCCCTTGCCTTTGCATTACTGTCTTTTAATGCCGCAGCAGTGAG
CCCACCACATCCAACGGGATTAAATGCACCTATGATCAGTGTCGCGAGTTTCAACCATAAAAATTATGCCGAGCAAGAAG
CCACGAAAATGTTTCCAGCGCCTGAGGCGGGTATGGTGCAACATATTTTGACCTTACCTAAACTCGAAAATGAAGACGAC
TACATGGTCGAAATCCAAATTGGCCAAACCCAATTAGTCGACTGTAATAAGCATGGTCTGAACGGCGAGTTAAAAGAACT
CTCGGTTAAGGGCTGGGGTTATAGCTATTATCAAGTGTCAGAAGTATCTGAAGGCCCAAGCACTATGATGGCCTGTTTAG
AGATGGCGAAAAAAGAAGCCTTTGTCCGCATTCCAGGTGAACTTAAAATGCGTTACGACAGCCGTTTGCCTAAGGTATTT
TATCTACCAGAAGGCACAGAGCTGCGCTTTAGAACCTGGAAAGTCGATTCAACATATCACTACGCTAAATAA

Upstream 100 bases:

>100_bases
AACCCTTTTTTGCTATTACTACGTTTACAAAGATAAGAATACAGCAAATGATGGTACAACCATCTGTGCTAGGCCTTATC
AACATCACTAGGAGACTATT

Downstream 100 bases:

>100_bases
ACGCGCCTCAATATTAGTTGTTTATTTAATGGTATTACTGCGGTGATATAAAGGGCATATCTTACAAGATATGCCCTTTT
TTTTCAGCAAGCTGCGTCAG

Product: ecotin

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 183; Mature: 183

Protein sequence:

>183_residues
MKLTHLFNTAALPLAFALLSFNAAAVSPPHPTGLNAPMISVASFNHKNYAEQEATKMFPAPEAGMVQHILTLPKLENEDD
YMVEIQIGQTQLVDCNKHGLNGELKELSVKGWGYSYYQVSEVSEGPSTMMACLEMAKKEAFVRIPGELKMRYDSRLPKVF
YLPEGTELRFRTWKVDSTYHYAK

Sequences:

>Translated_183_residues
MKLTHLFNTAALPLAFALLSFNAAAVSPPHPTGLNAPMISVASFNHKNYAEQEATKMFPAPEAGMVQHILTLPKLENEDD
YMVEIQIGQTQLVDCNKHGLNGELKELSVKGWGYSYYQVSEVSEGPSTMMACLEMAKKEAFVRIPGELKMRYDSRLPKVF
YLPEGTELRFRTWKVDSTYHYAK
>Mature_183_residues
MKLTHLFNTAALPLAFALLSFNAAAVSPPHPTGLNAPMISVASFNHKNYAEQEATKMFPAPEAGMVQHILTLPKLENEDD
YMVEIQIGQTQLVDCNKHGLNGELKELSVKGWGYSYYQVSEVSEGPSTMMACLEMAKKEAFVRIPGELKMRYDSRLPKVF
YLPEGTELRFRTWKVDSTYHYAK

Specific function: General inhibitor of family S1 serine proteases [H]

COG id: COG4574

COG function: function code R; Serine protease inhibitor ecotin

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the protease inhibitor I11 (ecotin) family [H]

Homologues:

Organism=Escherichia coli, GI1788538, Length=148, Percent_Identity=37.1621621621622, Blast_Score=102, Evalue=2e-23,

Paralogues:

None

Copy number: 260 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005658
- InterPro:   IPR023189
- InterPro:   IPR023084 [H]

Pfam domain/function: PF03974 Ecotin [H]

EC number: NA

Molecular weight: Translated: 20607; Mature: 20607

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLTHLFNTAALPLAFALLSFNAAAVSPPHPTGLNAPMISVASFNHKNYAEQEATKMFPA
CCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHCCCC
PEAGMVQHILTLPKLENEDDYMVEIQIGQTQLVDCNKHGLNGELKELSVKGWGYSYYQVS
CCHHHHHHHHHCCCCCCCCCEEEEEEECCEEEEECCCCCCCCCCEEEEECCCCEEEEEEE
EVSEGPSTMMACLEMAKKEAFVRIPGELKMRYDSRLPKVFYLPEGTELRFRTWKVDSTYH
CCCCCHHHHHHHHHHHHCCEEEECCCCEEEEECCCCCEEEECCCCCEEEEEEEEECCEEE
YAK
CCC
>Mature Secondary Structure
MKLTHLFNTAALPLAFALLSFNAAAVSPPHPTGLNAPMISVASFNHKNYAEQEATKMFPA
CCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHCCCC
PEAGMVQHILTLPKLENEDDYMVEIQIGQTQLVDCNKHGLNGELKELSVKGWGYSYYQVS
CCHHHHHHHHHCCCCCCCCCEEEEEEECCEEEEECCCCCCCCCCEEEEECCCCEEEEEEE
EVSEGPSTMMACLEMAKKEAFVRIPGELKMRYDSRLPKVFYLPEGTELRFRTWKVDSTYH
CCCCCHHHHHHHHHHHHCCEEEECCCCEEEEECCCCCEEEECCCCCEEEEEEEEECCEEE
YAK
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12368813 [H]