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The map label for this gene is ruvA [H]

Identifier: 117920401

GI number: 117920401

Start: 2327610

End: 2328227

Strand: Direct

Name: ruvA [H]

Synonym: Shewana3_1956

Alternate gene names: 117920401

Gene position: 2327610-2328227 (Clockwise)

Preceding gene: 117920400

Following gene: 117920402

Centisome position: 46.81

GC content: 49.84

Gene sequence:

>618_bases
ATGATAGGTCGTTTACGTGGCGTGTTAATTGAAAAGCAAGCGCCAGAGGTGTTGATTGATGTCAATGGCGTGGGGTACGA
GTTACAGATGCCCCTCACCAGCTTCTATGAACTCCCCGAGGTCAATCAACCGACCACAGTGTATACCCATTTTGTGGTGC
GTGAAGATGCCCAGCTGCTTTACGGCTTTATCACTAAACAAGAGCGTTCACTGTTTCGCTTGCTTATCAAGGCCAACGGT
GTGGGTCCTAAACTGGCGTTAACCATTCTTTCTGGCATGACCGCCAGCGAGTTTGTGGGCTGTGTCGAGCGTGATGATAT
AGTGACGCTGGTGAAATTACCCGGTGTCGGTAAAAAGACTGCCGAACGTTTATTGGTTGAGATGCGCGATAAATTGAAGA
GCTTGATGGAGGCATCCGTAGGCTCTGAGCGTGAGTTCGTGCTGCAATCTAACTATTCACCGGCTCCGACGGTCAACAGT
GCCGAAGAGGATGCGATTTCAGCCTTGATCTCCCTCGGCTATAAACCACCACAGGCGAGTAAAGCCGTTTCTGCCGCCTA
TAAAGAAGGCATGGACAGTGAGACCTTGATTAAGGCCGCGTTAAAATCGATGCTCTAA

Upstream 100 bases:

>100_bases
CTGCGGATGCGCTCGGCGTTGCGGTATGTCATTATCACACCAATCAAAGTTTGGTCGCCTTAAGCGGCCGAGCGACAACA
AGAACATATGGACGGTACAG

Downstream 100 bases:

>100_bases
TGGCATGGTTTTCATTAAGGCTAGTGTTATATTGCGGTACGCGATTTTTGCAGCCAGTTAGGTTGCAACTGCACCAAAAT
AGCAAGTGCCGTATGTCGAT

Product: Holliday junction DNA helicase RuvA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 205; Mature: 205

Protein sequence:

>205_residues
MIGRLRGVLIEKQAPEVLIDVNGVGYELQMPLTSFYELPEVNQPTTVYTHFVVREDAQLLYGFITKQERSLFRLLIKANG
VGPKLALTILSGMTASEFVGCVERDDIVTLVKLPGVGKKTAERLLVEMRDKLKSLMEASVGSEREFVLQSNYSPAPTVNS
AEEDAISALISLGYKPPQASKAVSAAYKEGMDSETLIKAALKSML

Sequences:

>Translated_205_residues
MIGRLRGVLIEKQAPEVLIDVNGVGYELQMPLTSFYELPEVNQPTTVYTHFVVREDAQLLYGFITKQERSLFRLLIKANG
VGPKLALTILSGMTASEFVGCVERDDIVTLVKLPGVGKKTAERLLVEMRDKLKSLMEASVGSEREFVLQSNYSPAPTVNS
AEEDAISALISLGYKPPQASKAVSAAYKEGMDSETLIKAALKSML
>Mature_205_residues
MIGRLRGVLIEKQAPEVLIDVNGVGYELQMPLTSFYELPEVNQPTTVYTHFVVREDAQLLYGFITKQERSLFRLLIKANG
VGPKLALTILSGMTASEFVGCVERDDIVTLVKLPGVGKKTAERLLVEMRDKLKSLMEASVGSEREFVLQSNYSPAPTVNS
AEEDAISALISLGYKPPQASKAVSAAYKEGMDSETLIKAALKSML

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG0632

COG function: function code L; Holliday junction resolvasome, DNA-binding subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvA family [H]

Homologues:

Organism=Escherichia coli, GI1788168, Length=205, Percent_Identity=60.4878048780488, Blast_Score=249, Evalue=1e-67,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011114
- InterPro:   IPR013849
- InterPro:   IPR003583
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR000085
- InterPro:   IPR010994 [H]

Pfam domain/function: PF07499 RuvA_C; PF01330 RuvA_N [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 22440; Mature: 22440

Theoretical pI: Translated: 5.40; Mature: 5.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIGRLRGVLIEKQAPEVLIDVNGVGYELQMPLTSFYELPEVNQPTTVYTHFVVREDAQLL
CCCCHHHEEEECCCCEEEEEECCCCEEEECCHHHHHCCCCCCCCCEEEEEEEECCCHHHH
YGFITKQERSLFRLLIKANGVGPKLALTILSGMTASEFVGCVERDDIVTLVKLPGVGKKT
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHCCCCCEEEEEECCCCCHHH
AERLLVEMRDKLKSLMEASVGSEREFVLQSNYSPAPTVNSAEEDAISALISLGYKPPQAS
HHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHCCCCCCCHH
KAVSAAYKEGMDSETLIKAALKSML
HHHHHHHHCCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MIGRLRGVLIEKQAPEVLIDVNGVGYELQMPLTSFYELPEVNQPTTVYTHFVVREDAQLL
CCCCHHHEEEECCCCEEEEEECCCCEEEECCHHHHHCCCCCCCCCEEEEEEEECCCHHHH
YGFITKQERSLFRLLIKANGVGPKLALTILSGMTASEFVGCVERDDIVTLVKLPGVGKKT
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHHHHHCCCCCEEEEEECCCCCHHH
AERLLVEMRDKLKSLMEASVGSEREFVLQSNYSPAPTVNSAEEDAISALISLGYKPPQAS
HHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHCCCCCCCHH
KAVSAAYKEGMDSETLIKAALKSML
HHHHHHHHCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA