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The map label for this gene is ruvC [H]

Identifier: 117920400

GI number: 117920400

Start: 2327092

End: 2327613

Strand: Direct

Name: ruvC [H]

Synonym: Shewana3_1955

Alternate gene names: 117920400

Gene position: 2327092-2327613 (Clockwise)

Preceding gene: 117920399

Following gene: 117920401

Centisome position: 46.8

GC content: 52.49

Gene sequence:

>522_bases
ATGGCGATTATTTTAGGGGTTGACCCTGGTTCTCGGATCACAGGTTACGGCGTTATCCAATGCCTAGGGCGACAGCAACT
TTATTTGGGCAGCGGCTGCATTCGCACCTCGGGCGAGGATTTACCATTAAGACTCAAGCAAATCTTTGATGGGATCAGTG
AAATTATTCGCCAATACCAACCCGATGAATTTGCGATTGAGCGGGTGTTTCTCGCCAAGAATGCCGACTCGGCCTTGAAA
TTGGGCCAAGCCCGTGGTGCGGCTATCGTGGCAGCGACAGTAGCCAACTTACCCGTTGCCGAATACAGTGCTACCCAAAT
TAAGAATGCGGTGGTCGGAACGGGGCGAGCCAAGAAAGAACAGGTTCAACATATGATCCAGCAATTGCTTAAGCTGCCCG
CGGCGCCACAGGCCGACGCTGCGGATGCGCTCGGCGTTGCGGTATGTCATTATCACACCAATCAAAGTTTGGTCGCCTTA
AGCGGCCGAGCGACAACAAGAACATATGGACGGTACAGATGA

Upstream 100 bases:

>100_bases
AAATTTACCTTTGATTTATTGATGTTTTTTGTGCTGTTGCTCGGCTTACAACCGCCGTTATCTAGGTTGAATAAAGTCGA
GCACAGACATTAGGGATAGC

Downstream 100 bases:

>100_bases
TAGGTCGTTTACGTGGCGTGTTAATTGAAAAGCAAGCGCCAGAGGTGTTGATTGATGTCAATGGCGTGGGGTACGAGTTA
CAGATGCCCCTCACCAGCTT

Product: Holliday junction resolvase

Products: NA

Alternate protein names: Holliday junction nuclease ruvC; Holliday junction resolvase ruvC [H]

Number of amino acids: Translated: 173; Mature: 172

Protein sequence:

>173_residues
MAIILGVDPGSRITGYGVIQCLGRQQLYLGSGCIRTSGEDLPLRLKQIFDGISEIIRQYQPDEFAIERVFLAKNADSALK
LGQARGAAIVAATVANLPVAEYSATQIKNAVVGTGRAKKEQVQHMIQQLLKLPAAPQADAADALGVAVCHYHTNQSLVAL
SGRATTRTYGRYR

Sequences:

>Translated_173_residues
MAIILGVDPGSRITGYGVIQCLGRQQLYLGSGCIRTSGEDLPLRLKQIFDGISEIIRQYQPDEFAIERVFLAKNADSALK
LGQARGAAIVAATVANLPVAEYSATQIKNAVVGTGRAKKEQVQHMIQQLLKLPAAPQADAADALGVAVCHYHTNQSLVAL
SGRATTRTYGRYR
>Mature_172_residues
AIILGVDPGSRITGYGVIQCLGRQQLYLGSGCIRTSGEDLPLRLKQIFDGISEIIRQYQPDEFAIERVFLAKNADSALKL
GQARGAAIVAATVANLPVAEYSATQIKNAVVGTGRAKKEQVQHMIQQLLKLPAAPQADAADALGVAVCHYHTNQSLVALS
GRATTRTYGRYR

Specific function: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leav

COG id: COG0817

COG function: function code L; Holliday junction resolvasome, endonuclease subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvC family [H]

Homologues:

Organism=Escherichia coli, GI1788170, Length=173, Percent_Identity=64.7398843930636, Blast_Score=207, Evalue=4e-55,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012337
- InterPro:   IPR020563
- InterPro:   IPR002176 [H]

Pfam domain/function: PF02075 RuvC [H]

EC number: =3.1.22.4 [H]

Molecular weight: Translated: 18580; Mature: 18448

Theoretical pI: Translated: 9.64; Mature: 9.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIILGVDPGSRITGYGVIQCLGRQQLYLGSGCIRTSGEDLPLRLKQIFDGISEIIRQYQ
CEEEEECCCCCCCCHHHHHHHHCCCEEEECCCEECCCCCCCCHHHHHHHHHHHHHHHHCC
PDEFAIERVFLAKNADSALKLGQARGAAIVAATVANLPVAEYSATQIKNAVVGTGRAKKE
CCHHHHHHHHHHCCCCHHHHHHCCCCCEEEEEHHHCCCCCHHHHHHHHHHHHCCCCHHHH
QVQHMIQQLLKLPAAPQADAADALGVAVCHYHTNQSLVALSGRATTRTYGRYR
HHHHHHHHHHHCCCCCCCCCHHHHHEEEEEEECCCEEEEECCCCCCCCCCCCC
>Mature Secondary Structure 
AIILGVDPGSRITGYGVIQCLGRQQLYLGSGCIRTSGEDLPLRLKQIFDGISEIIRQYQ
EEEEECCCCCCCCHHHHHHHHCCCEEEECCCEECCCCCCCCHHHHHHHHHHHHHHHHCC
PDEFAIERVFLAKNADSALKLGQARGAAIVAATVANLPVAEYSATQIKNAVVGTGRAKKE
CCHHHHHHHHHHCCCCHHHHHHCCCCCEEEEEHHHCCCCCHHHHHHHHHHHHCCCCHHHH
QVQHMIQQLLKLPAAPQADAADALGVAVCHYHTNQSLVALSGRATTRTYGRYR
HHHHHHHHHHHCCCCCCCCCHHHHHEEEEEEECCCEEEEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA