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The map label for this gene is cirA [H]

Identifier: 117920306

GI number: 117920306

Start: 2202821

End: 2204782

Strand: Reverse

Name: cirA [H]

Synonym: Shewana3_1861

Alternate gene names: 117920306

Gene position: 2204782-2202821 (Counterclockwise)

Preceding gene: 117920307

Following gene: 117920303

Centisome position: 44.34

GC content: 50.31

Gene sequence:

>1962_bases
ATGCCTGCACAACCCGATTTTACCCCTCGTCTGTCGCGATTTTCCCGCAAAGCCCTCCCCTTAGCTATCAGCCTCGGCCT
CAGTGCTATATCGGCAACGGCTCTGGCCAACAATAGCGCCACAGGCGAGATGGAACGTATGGTGATCACTGCGACGCAAA
CCAAACACTCTGAGCTCTCGGCGCCAGCATCAGTATCAGTGATTAATCGCACCGAGCTTGAAGCCTTAGTGATTGATGAC
CTCGCCAGTGCAGTGCGTTATTTACAGGGAGTGAATATCAGTGAAGGTACGCCCTATGGCCGCAATGAAATCAGCCTTAG
GGGTCTGGATTCTGACTACACCTTAATCTTGATCAATGGCCGCCGCGTCAATTCTCGCGAGGCGCTCACCTCCAACTATG
GCAATGACTTCGACCTGTCATCTATCCCCATGTCTGCTATCGAGCGCATTGAGTTAGTTCGCGGCCCCATGTCATCCCTC
TATGGCTCCGAAGCCTTAGGTGGCGTAGTCAACGTTATCCTGCGCCAACCAACCGAAACTTGGCAAACCAGCGTCGGCGT
GCAATACGACACACCAACCAGTGGTGAAGGTGGCGATAGCACTAAATACAACTTCTACACAAGCGGCGCACTCGTGAAGG
ATAAACTGCTGGCGAACTTGATTGTCGATAGCAATAAACGTGATGCCTGGCGTTCAGACTTAAAGCCAACTATCGATGCA
CTCGAAGACAGGGATGAGATCAGCGCCTTAGCCAATCTGCAATGGTTAATCGACAAGCAGCAGGATCTGCAATTCGATAT
CAGTTACGCCAGCGATGAGCGTGAGTCCGACTGGAATAACTACGGCACGATTCTGACCAACAACCAACAGGCGGAGCGCA
TTAGCTCAGGTTTGACCCATAACGGCCGTTGGGACTGGGGTGATACTCGCCTGCGTTACTATTATGAAAATGTCGAAGTA
ACCGATGATTCGGCGCTGATCGCGCAAATTGGCCATATCACTCAAACCAACCACAATCTCGACGGCCAAACCACAGTGTT
ACTCGGCGAGCATATGCTGACGGGCGGCGCCGAATACCGTTGGACCAAGCTTGAGAACAGCCGCAATATTTTAGGCGATG
GCACCTTAGACGACAGTCAGTCGGCACTGTATCTGCAGGATGAGTTCAGTTTAGGCGAACTGAGTCTCACCCTCGGTGGC
CGTGTCGATCACCACGATGTGTATGGCACTGAGTTTAGTCCTCGCCTCTATCTGGTTTATCCACTCAGCTCCGAATGGGT
GATCAAAGGTGGCGGTGGTAAAGCCTTTAAAGCACCGAATATGTCGCAGTCCCAAGCCGATTATATTATCCCAGCCTGTC
GTGGTGCCTGCTCTGTGGCGGGCAATCCCGACTTACAGCCCGAAACCTCGGTGAACTACGAGCTATCGACCCAATACCAA
ACCGCAGATTTTGGCGGCTCCGTCACCTATTTCCATAATGATGTAGAAAACAAAATCATCACCGAGACCTGGGACAGAAC
CCCGGGCGCCGTGCTCACCTATCAAAACGTTAACGAAGCTAAGATCACTGGTTGGGAATTACAGGCATGGTACGACTTAA
CCGACAGTTTAAGTATCAGTGGTAACTACAGTAAAACCGATGCCAAGGATAAACAAAATGGCGCGCCTTTTACTTTAACG
CCTGAAGATAGCTACAACCTGAAACTGCAATGGCAGGCGTTAGAGGGATTATCCACCTTTATTGCTTACCACTACACGGG
TGAACAATATCTGAGAACCAACGTTAAATCAGATGGTTATGGTTCACTTGATTTAGGTGTGAATTATCAAATCAACCCTA
TGTTTAGAGTAAAACTAGGGGTGACTAACTTGACGGATGCCGAGCGCGATCAAATTGCCACCGATTTGGATTACATTCAA
AAGAGCCGCAGCGTGTATGCTGGGGTAACGGCAAGCTTCTAA

Upstream 100 bases:

>100_bases
ATAAAATTTACACTGGCTTTACACTTAACTGTGGGATAGCGACTTGTTGACGCATTTAAGAATAATTATCATTCGCCAAA
ATTTTACAAGGAAGAATGAT

Downstream 100 bases:

>100_bases
TCCTGAGATCATGGCCTGCCGCGGCAGGCCATGCTTACCCTCGAATATCAGCAAAATAAGTTTAGATTAATTTTTTATAG
GCTCTCAGTGTTTCAACGCG

Product: TonB-dependent receptor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 653; Mature: 652

Protein sequence:

>653_residues
MPAQPDFTPRLSRFSRKALPLAISLGLSAISATALANNSATGEMERMVITATQTKHSELSAPASVSVINRTELEALVIDD
LASAVRYLQGVNISEGTPYGRNEISLRGLDSDYTLILINGRRVNSREALTSNYGNDFDLSSIPMSAIERIELVRGPMSSL
YGSEALGGVVNVILRQPTETWQTSVGVQYDTPTSGEGGDSTKYNFYTSGALVKDKLLANLIVDSNKRDAWRSDLKPTIDA
LEDRDEISALANLQWLIDKQQDLQFDISYASDERESDWNNYGTILTNNQQAERISSGLTHNGRWDWGDTRLRYYYENVEV
TDDSALIAQIGHITQTNHNLDGQTTVLLGEHMLTGGAEYRWTKLENSRNILGDGTLDDSQSALYLQDEFSLGELSLTLGG
RVDHHDVYGTEFSPRLYLVYPLSSEWVIKGGGGKAFKAPNMSQSQADYIIPACRGACSVAGNPDLQPETSVNYELSTQYQ
TADFGGSVTYFHNDVENKIITETWDRTPGAVLTYQNVNEAKITGWELQAWYDLTDSLSISGNYSKTDAKDKQNGAPFTLT
PEDSYNLKLQWQALEGLSTFIAYHYTGEQYLRTNVKSDGYGSLDLGVNYQINPMFRVKLGVTNLTDAERDQIATDLDYIQ
KSRSVYAGVTASF

Sequences:

>Translated_653_residues
MPAQPDFTPRLSRFSRKALPLAISLGLSAISATALANNSATGEMERMVITATQTKHSELSAPASVSVINRTELEALVIDD
LASAVRYLQGVNISEGTPYGRNEISLRGLDSDYTLILINGRRVNSREALTSNYGNDFDLSSIPMSAIERIELVRGPMSSL
YGSEALGGVVNVILRQPTETWQTSVGVQYDTPTSGEGGDSTKYNFYTSGALVKDKLLANLIVDSNKRDAWRSDLKPTIDA
LEDRDEISALANLQWLIDKQQDLQFDISYASDERESDWNNYGTILTNNQQAERISSGLTHNGRWDWGDTRLRYYYENVEV
TDDSALIAQIGHITQTNHNLDGQTTVLLGEHMLTGGAEYRWTKLENSRNILGDGTLDDSQSALYLQDEFSLGELSLTLGG
RVDHHDVYGTEFSPRLYLVYPLSSEWVIKGGGGKAFKAPNMSQSQADYIIPACRGACSVAGNPDLQPETSVNYELSTQYQ
TADFGGSVTYFHNDVENKIITETWDRTPGAVLTYQNVNEAKITGWELQAWYDLTDSLSISGNYSKTDAKDKQNGAPFTLT
PEDSYNLKLQWQALEGLSTFIAYHYTGEQYLRTNVKSDGYGSLDLGVNYQINPMFRVKLGVTNLTDAERDQIATDLDYIQ
KSRSVYAGVTASF
>Mature_652_residues
PAQPDFTPRLSRFSRKALPLAISLGLSAISATALANNSATGEMERMVITATQTKHSELSAPASVSVINRTELEALVIDDL
ASAVRYLQGVNISEGTPYGRNEISLRGLDSDYTLILINGRRVNSREALTSNYGNDFDLSSIPMSAIERIELVRGPMSSLY
GSEALGGVVNVILRQPTETWQTSVGVQYDTPTSGEGGDSTKYNFYTSGALVKDKLLANLIVDSNKRDAWRSDLKPTIDAL
EDRDEISALANLQWLIDKQQDLQFDISYASDERESDWNNYGTILTNNQQAERISSGLTHNGRWDWGDTRLRYYYENVEVT
DDSALIAQIGHITQTNHNLDGQTTVLLGEHMLTGGAEYRWTKLENSRNILGDGTLDDSQSALYLQDEFSLGELSLTLGGR
VDHHDVYGTEFSPRLYLVYPLSSEWVIKGGGGKAFKAPNMSQSQADYIIPACRGACSVAGNPDLQPETSVNYELSTQYQT
ADFGGSVTYFHNDVENKIITETWDRTPGAVLTYQNVNEAKITGWELQAWYDLTDSLSISGNYSKTDAKDKQNGAPFTLTP
EDSYNLKLQWQALEGLSTFIAYHYTGEQYLRTNVKSDGYGSLDLGVNYQINPMFRVKLGVTNLTDAERDQIATDLDYIQK
SRSVYAGVTASF

Specific function: Not yet known. Postulated to participate in iron transport. Outer membrane receptor for colicins IA and IB [H]

COG id: COG4771

COG function: function code P; Outer membrane receptor for ferrienterochelin and colicins

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tonB-dependent receptor family [H]

Homologues:

Organism=Escherichia coli, GI1788478, Length=690, Percent_Identity=34.9275362318841, Blast_Score=332, Evalue=4e-92,
Organism=Escherichia coli, GI1786798, Length=655, Percent_Identity=26.5648854961832, Blast_Score=166, Evalue=3e-42,
Organism=Escherichia coli, GI1790405, Length=183, Percent_Identity=28.9617486338798, Blast_Score=87, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR010916
- InterPro:   IPR010917 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 72286; Mature: 72154

Theoretical pI: Translated: 4.42; Mature: 4.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPAQPDFTPRLSRFSRKALPLAISLGLSAISATALANNSATGEMERMVITATQTKHSELS
CCCCCCCCHHHHHHHHHCCCEEEECCHHHHHHHHHCCCCCCCCEEEEEEEEECCCCCCCC
APASVSVINRTELEALVIDDLASAVRYLQGVNISEGTPYGRNEISLRGLDSDYTLILING
CCCEEEEEECCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCEEEEEEEC
RRVNSREALTSNYGNDFDLSSIPMSAIERIELVRGPMSSLYGSEALGGVVNVILRQPTET
CCCCCHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCHHHHCCHHHHHHHHHHHHCCCCHH
WQTSVGVQYDTPTSGEGGDSTKYNFYTSGALVKDKLLANLIVDSNKRDAWRSDLKPTIDA
HHHCCCEEECCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHCCCCCCHHHHHCCCHHHHH
LEDRDEISALANLQWLIDKQQDLQFDISYASDERESDWNNYGTILTNNQQAERISSGLTH
HCCHHHHHHHHHHHEEECCCCCCEEEEEECCCCCCCCCCCCCCEEECCHHHHHHHHCCCC
NGRWDWGDTRLRYYYENVEVTDDSALIAQIGHITQTNHNLDGQTTVLLGEHMLTGGAEYR
CCCCCCCCCEEEEEEECEEECCCCHHHHHHCCCCCCCCCCCCCEEEEEECHHHCCCCCEE
WTKLENSRNILGDGTLDDSQSALYLQDEFSLGELSLTLGGRVDHHDVYGTEFSPRLYLVY
EEEECCCCCEECCCCCCCCCCEEEEEECCCCCEEEEEECCEECCCCCCCCCCCCEEEEEE
PLSSEWVIKGGGGKAFKAPNMSQSQADYIIPACRGACSVAGNPDLQPETSVNYELSTQYQ
ECCCCEEEECCCCCEEECCCCCCCCCCEEEECCCCCEECCCCCCCCCCCCCCEEEECEEE
TADFGGSVTYFHNDVENKIITETWDRTPGAVLTYQNVNEAKITGWELQAWYDLTDSLSIS
ECCCCCEEEEEECCCCCCEEHHHCCCCCCEEEEECCCCCCEEEEEEEEEEECCCCCEEEC
GNYSKTDAKDKQNGAPFTLTPEDSYNLKLQWQALEGLSTFIAYHYTGEQYLRTNVKSDGY
CCCCCCCCCCCCCCCCEEECCCCCCEEEEEEEHHHCCEEEEEEEECCHHHHHCCCCCCCC
GSLDLGVNYQINPMFRVKLGVTNLTDAERDQIATDLDYIQKSRSVYAGVTASF
CEEEECCEEEECCEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCEEEEEEECC
>Mature Secondary Structure 
PAQPDFTPRLSRFSRKALPLAISLGLSAISATALANNSATGEMERMVITATQTKHSELS
CCCCCCCHHHHHHHHHCCCEEEECCHHHHHHHHHCCCCCCCCEEEEEEEEECCCCCCCC
APASVSVINRTELEALVIDDLASAVRYLQGVNISEGTPYGRNEISLRGLDSDYTLILING
CCCEEEEEECCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCEEEEEEEC
RRVNSREALTSNYGNDFDLSSIPMSAIERIELVRGPMSSLYGSEALGGVVNVILRQPTET
CCCCCHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCHHHHCCHHHHHHHHHHHHCCCCHH
WQTSVGVQYDTPTSGEGGDSTKYNFYTSGALVKDKLLANLIVDSNKRDAWRSDLKPTIDA
HHHCCCEEECCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHCCCCCCHHHHHCCCHHHHH
LEDRDEISALANLQWLIDKQQDLQFDISYASDERESDWNNYGTILTNNQQAERISSGLTH
HCCHHHHHHHHHHHEEECCCCCCEEEEEECCCCCCCCCCCCCCEEECCHHHHHHHHCCCC
NGRWDWGDTRLRYYYENVEVTDDSALIAQIGHITQTNHNLDGQTTVLLGEHMLTGGAEYR
CCCCCCCCCEEEEEEECEEECCCCHHHHHHCCCCCCCCCCCCCEEEEEECHHHCCCCCEE
WTKLENSRNILGDGTLDDSQSALYLQDEFSLGELSLTLGGRVDHHDVYGTEFSPRLYLVY
EEEECCCCCEECCCCCCCCCCEEEEEECCCCCEEEEEECCEECCCCCCCCCCCCEEEEEE
PLSSEWVIKGGGGKAFKAPNMSQSQADYIIPACRGACSVAGNPDLQPETSVNYELSTQYQ
ECCCCEEEECCCCCEEECCCCCCCCCCEEEECCCCCEECCCCCCCCCCCCCCEEEECEEE
TADFGGSVTYFHNDVENKIITETWDRTPGAVLTYQNVNEAKITGWELQAWYDLTDSLSIS
ECCCCCEEEEEECCCCCCEEHHHCCCCCCEEEEECCCCCCEEEEEEEEEEECCCCCEEEC
GNYSKTDAKDKQNGAPFTLTPEDSYNLKLQWQALEGLSTFIAYHYTGEQYLRTNVKSDGY
CCCCCCCCCCCCCCCCEEECCCCCCEEEEEEEHHHCCEEEEEEEECCHHHHHCCCCCCCC
GSLDLGVNYQINPMFRVKLGVTNLTDAERDQIATDLDYIQKSRSVYAGVTASF
CEEEECCEEEECCEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2644220; 9278503; 3316180; 1315732; 2160948 [H]