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The map label for this gene is umuD [H]

Identifier: 117920280

GI number: 117920280

Start: 2174380

End: 2175204

Strand: Reverse

Name: umuD [H]

Synonym: Shewana3_1833

Alternate gene names: 117920280

Gene position: 2175204-2174380 (Counterclockwise)

Preceding gene: 117920281

Following gene: 117920279

Centisome position: 43.75

GC content: 43.03

Gene sequence:

>825_bases
ATGCTCGCTACAATTACTGTATTTACATACAGTAATTATATTGCTATGCGTGTTTACCCTATTATTCCTTGGCCCGCTCA
CGCGGGAATTAGCGGCTTTGAAAGCCCAGCAGCTGAATATACTCAGCTTGGATTGTGTCTTGATGATTTACTCGTATTGC
ACCCCAGTGCAACACGGCTTTGCATCGCTCAAGGCGACTCGATGAAAGGTGTCGGCATATTCGATGGCGATCTGCTGATC
ATCGATCGCCATATAAAACCTCACACAGGGTGTGTGATTTATGGCCAACTCAATGGCGAGTTCATCTGCAAAATCTATGA
TGAAAAACAGAGAATGCTGCTCTCTTCCCATGAAAACTGCCAAGCCATAGTGATACACGATTACGATGATTTTTGCGTTG
AAGGGGTCGTGATCAGAACCTTGAGGCAACATTTCTATCTCAATGATTCTATTAATATTGCTTCAGACTATTCTGAGCTT
AGGACAAACCTGGATGATCTATTGGTATTACACCCTTGTGCAACCTGGTTTGGTGTCGCCCAAGGGGACTCCATGCAAGA
TGAAGGGATATATGATAGAGATATATTAATTATTGACCGACAAGTTAACGCATTACAGGGAGCCGTTATCGTTGCCCAGC
TCAATGGCGAGTTTATCTGCAAAATTTTTGATAAAAAACGCAGGATGTTACTGTCTGCTAATCCGCAATACCATGCCGTG
CCGATACGAGATTGCGACACTTTTAGTGTTGAAGGAATCGTTATTCGCTCGGTTAGAATGCATTTTAAATCTTCATTACA
GGGCTTATGGTCATGTACGCCTTAG

Upstream 100 bases:

>100_bases
TGACTGATACTAAGTAAAACACTAACTTAATCATGTGGTTAACCTGTACTGACTGACTAGCAAGCCAATTTAACACTCAG
TCCCATTTGCGAATAGAACA

Downstream 100 bases:

>100_bases
TCGATGCCAACTCGTTTTATTGCTCCGCTGAGCAAGTGTTCCGCCCCGATTGGCGCGGCAAACCGATTATCGTACTAAGC
AATAACGATGGCTGTATCGT

Product: putative prophage repressor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 274; Mature: 274

Protein sequence:

>274_residues
MLATITVFTYSNYIAMRVYPIIPWPAHAGISGFESPAAEYTQLGLCLDDLLVLHPSATRLCIAQGDSMKGVGIFDGDLLI
IDRHIKPHTGCVIYGQLNGEFICKIYDEKQRMLLSSHENCQAIVIHDYDDFCVEGVVIRTLRQHFYLNDSINIASDYSEL
RTNLDDLLVLHPCATWFGVAQGDSMQDEGIYDRDILIIDRQVNALQGAVIVAQLNGEFICKIFDKKRRMLLSANPQYHAV
PIRDCDTFSVEGIVIRSVRMHFKSSLQGLWSCTP

Sequences:

>Translated_274_residues
MLATITVFTYSNYIAMRVYPIIPWPAHAGISGFESPAAEYTQLGLCLDDLLVLHPSATRLCIAQGDSMKGVGIFDGDLLI
IDRHIKPHTGCVIYGQLNGEFICKIYDEKQRMLLSSHENCQAIVIHDYDDFCVEGVVIRTLRQHFYLNDSINIASDYSEL
RTNLDDLLVLHPCATWFGVAQGDSMQDEGIYDRDILIIDRQVNALQGAVIVAQLNGEFICKIFDKKRRMLLSANPQYHAV
PIRDCDTFSVEGIVIRSVRMHFKSSLQGLWSCTP
>Mature_274_residues
MLATITVFTYSNYIAMRVYPIIPWPAHAGISGFESPAAEYTQLGLCLDDLLVLHPSATRLCIAQGDSMKGVGIFDGDLLI
IDRHIKPHTGCVIYGQLNGEFICKIYDEKQRMLLSSHENCQAIVIHDYDDFCVEGVVIRTLRQHFYLNDSINIASDYSEL
RTNLDDLLVLHPCATWFGVAQGDSMQDEGIYDRDILIIDRQVNALQGAVIVAQLNGEFICKIFDKKRRMLLSANPQYHAV
PIRDCDTFSVEGIVIRSVRMHFKSSLQGLWSCTP

Specific function: Involved in UV protection and mutation. Essential for induced (or SOS) mutagenesis. May modify the DNA replication machinery to allow bypass synthesis across a damaged template [H]

COG id: COG1974

COG function: function code KT; SOS-response transcriptional repressors (RecA-mediated autopeptidases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S24 family [H]

Homologues:

Organism=Escherichia coli, GI1787431, Length=107, Percent_Identity=41.1214953271028, Blast_Score=84, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006197
- InterPro:   IPR019759
- InterPro:   IPR015927
- InterPro:   IPR011056 [H]

Pfam domain/function: PF00717 Peptidase_S24 [H]

EC number: 3.4.21.-

Molecular weight: Translated: 30847; Mature: 30847

Theoretical pI: Translated: 5.50; Mature: 5.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
3.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLATITVFTYSNYIAMRVYPIIPWPAHAGISGFESPAAEYTQLGLCLDDLLVLHPSATRL
CEEEEEEEEECCEEEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHEEECCCCCEE
CIAQGDSMKGVGIFDGDLLIIDRHIKPHTGCVIYGQLNGEFICKIYDEKQRMLLSSHENC
EEECCCCCCCEEEECCCEEEEECCCCCCCCEEEEEECCCEEEEEEECCHHHHHHCCCCCC
QAIVIHDYDDFCVEGVVIRTLRQHFYLNDSINIASDYSELRTNLDDLLVLHPCATWFGVA
EEEEEECCCHHHHHHHHHHHHHHHEEECCCCEECCCHHHHHCCHHHEEEEECHHHHHCCC
QGDSMQDEGIYDRDILIIDRQVNALQGAVIVAQLNGEFICKIFDKKRRMLLSANPQYHAV
CCCCCCCCCCCCCEEEEEECCCCCCCCEEEEEEECCCEEEEEECCCCEEEEECCCCEEEE
PIRDCDTFSVEGIVIRSVRMHFKSSLQGLWSCTP
ECCCCCCEEECEEEEHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MLATITVFTYSNYIAMRVYPIIPWPAHAGISGFESPAAEYTQLGLCLDDLLVLHPSATRL
CEEEEEEEEECCEEEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHEEECCCCCEE
CIAQGDSMKGVGIFDGDLLIIDRHIKPHTGCVIYGQLNGEFICKIYDEKQRMLLSSHENC
EEECCCCCCCEEEECCCEEEEECCCCCCCCEEEEEECCCEEEEEEECCHHHHHHCCCCCC
QAIVIHDYDDFCVEGVVIRTLRQHFYLNDSINIASDYSELRTNLDDLLVLHPCATWFGVA
EEEEEECCCHHHHHHHHHHHHHHHEEECCCCEECCCHHHHHCCHHHEEEEECHHHHHCCC
QGDSMQDEGIYDRDILIIDRQVNALQGAVIVAQLNGEFICKIFDKKRRMLLSANPQYHAV
CCCCCCCCCCCCCEEEEEECCCCCCCCEEEEEEECCCEEEEEECCCCEEEEECCCCEEEE
PIRDCDTFSVEGIVIRSVRMHFKSSLQGLWSCTP
ECCCCCCEEECEEEEHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]