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The map label for this gene is umuC [H]

Identifier: 117920279

GI number: 117920279

Start: 2173136

End: 2174392

Strand: Reverse

Name: umuC [H]

Synonym: Shewana3_1832

Alternate gene names: 117920279

Gene position: 2174392-2173136 (Counterclockwise)

Preceding gene: 117920280

Following gene: 117920278

Centisome position: 43.73

GC content: 46.78

Gene sequence:

>1257_bases
ATGTACGCCTTAGTCGATGCCAACTCGTTTTATTGCTCCGCTGAGCAAGTGTTCCGCCCCGATTGGCGCGGCAAACCGAT
TATCGTACTAAGCAATAACGATGGCTGTATCGTGGCAGCCAACCGTCAGGCCAGAGAACTCGGCATCCCCAAATTTGCGC
CGTATTTTCATGTCAAAGAACAATGCGCCAAACTGGGGGTAATAGTGTGTTCTAGCAACTACGAGCTCTATGCCGATTTG
TCGGCAAAAATGATGGAAATCATCGGCCGCTTCGCTCCAGACCAACATATTTACTCCATTGATGAATCATTTTTATCCTT
CAAGCACTGCCACACCAGCATCCCCTGCTTAAAAACACACGGCCTGCGCATCCGCCAAACCGTTTGGAAAGAAGCGCGCA
TCCCCGTTTGCGTTGGCATAGGTGCAACACTCACACTGGCTAAAATCGCTAATCATGCCGCTAAAAAATTACCCGGCTAT
CATGGTGTTTGCCTGATAGATAATGAACCTCAACGAATTGAAATTCTTAAACAACTCTTAGTCAGTGATGTATGGGGTAT
TGGGCGCCGCCTCAGCAAAAAACTGGTGAGTATGGGCATTCACACCGCTTACGATCTGGCACAAATGCCAACAGGTCTTG
CTCGCAAGCAATTCAGCATAGAGATAGAGCGAACCGTCCGAGAGCTTAATGGCACAGCCTGTAAACAATGGGATCACACA
CGGGCAGATAAACAACAGATATTTTCCACTCGCTCCGTGGGTGAGCGCATCATGGATTTTGAGGCGTTACTACAAGCATT
GAGCAAACACGTTGGGATTGCAGCGGCAAAAGCCAGAGCGCAGGGTTCATGCTGCAAATCGATGCTGATTTTTGCCAATA
ACTCCCCTTACGATGAACAACCCGTTGGTTTTAAATCCCTTATCCATTTCCCCACTGCAACCAATTGCACCATTGAGATG
ACGCAAGCAGCGTCTTTAGCAGCACCAAGATTATTTCGACCAGGAGTTAAGTACTACAAGATAGGAATAGGCCTGATAAA
TCTCGAACAAAATAGGTATCAACAACTCGATTTGTTCAATTTATCTAAAACTAAACCCACACTAATGAACGCATTTGATG
GAATAAATGCCCGTTATGGGCGAGATACCTTATTTTTAGCCGCACAAGGCATAGAACAGAAATGGGCAATGCGCCGCGCA
TTACTCACACCACAATACACCACGCTGTGGGGTGGCATACCTAGAGTAAAATGCTAG

Upstream 100 bases:

>100_bases
ATGCCGTGCCGATACGAGATTGCGACACTTTTAGTGTTGAAGGAATCGTTATTCGCTCGGTTAGAATGCATTTTAAATCT
TCATTACAGGGCTTATGGTC

Downstream 100 bases:

>100_bases
TCCTCAAGGCAAAAATTGCATTTTCCCCAATTAGTCCCAAAGCAAAAACGGGACTCCGTAAGTTACTGATTCCCGTGAGA
GAGGGAGTCTACTTCATGAT

Product: DNA-repair protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 418; Mature: 418

Protein sequence:

>418_residues
MYALVDANSFYCSAEQVFRPDWRGKPIIVLSNNDGCIVAANRQARELGIPKFAPYFHVKEQCAKLGVIVCSSNYELYADL
SAKMMEIIGRFAPDQHIYSIDESFLSFKHCHTSIPCLKTHGLRIRQTVWKEARIPVCVGIGATLTLAKIANHAAKKLPGY
HGVCLIDNEPQRIEILKQLLVSDVWGIGRRLSKKLVSMGIHTAYDLAQMPTGLARKQFSIEIERTVRELNGTACKQWDHT
RADKQQIFSTRSVGERIMDFEALLQALSKHVGIAAAKARAQGSCCKSMLIFANNSPYDEQPVGFKSLIHFPTATNCTIEM
TQAASLAAPRLFRPGVKYYKIGIGLINLEQNRYQQLDLFNLSKTKPTLMNAFDGINARYGRDTLFLAAQGIEQKWAMRRA
LLTPQYTTLWGGIPRVKC

Sequences:

>Translated_418_residues
MYALVDANSFYCSAEQVFRPDWRGKPIIVLSNNDGCIVAANRQARELGIPKFAPYFHVKEQCAKLGVIVCSSNYELYADL
SAKMMEIIGRFAPDQHIYSIDESFLSFKHCHTSIPCLKTHGLRIRQTVWKEARIPVCVGIGATLTLAKIANHAAKKLPGY
HGVCLIDNEPQRIEILKQLLVSDVWGIGRRLSKKLVSMGIHTAYDLAQMPTGLARKQFSIEIERTVRELNGTACKQWDHT
RADKQQIFSTRSVGERIMDFEALLQALSKHVGIAAAKARAQGSCCKSMLIFANNSPYDEQPVGFKSLIHFPTATNCTIEM
TQAASLAAPRLFRPGVKYYKIGIGLINLEQNRYQQLDLFNLSKTKPTLMNAFDGINARYGRDTLFLAAQGIEQKWAMRRA
LLTPQYTTLWGGIPRVKC
>Mature_418_residues
MYALVDANSFYCSAEQVFRPDWRGKPIIVLSNNDGCIVAANRQARELGIPKFAPYFHVKEQCAKLGVIVCSSNYELYADL
SAKMMEIIGRFAPDQHIYSIDESFLSFKHCHTSIPCLKTHGLRIRQTVWKEARIPVCVGIGATLTLAKIANHAAKKLPGY
HGVCLIDNEPQRIEILKQLLVSDVWGIGRRLSKKLVSMGIHTAYDLAQMPTGLARKQFSIEIERTVRELNGTACKQWDHT
RADKQQIFSTRSVGERIMDFEALLQALSKHVGIAAAKARAQGSCCKSMLIFANNSPYDEQPVGFKSLIHFPTATNCTIEM
TQAASLAAPRLFRPGVKYYKIGIGLINLEQNRYQQLDLFNLSKTKPTLMNAFDGINARYGRDTLFLAAQGIEQKWAMRRA
LLTPQYTTLWGGIPRVKC

Specific function: Involved in UV protection and mutation. Essential for induced (or SOS) mutagenesis. May modify the DNA replication machinery to allow bypass synthesis across a damaged template [H]

COG id: COG0389

COG function: function code L; Nucleotidyltransferase/DNA polymerase involved in DNA repair

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 umuC domain [H]

Homologues:

Organism=Escherichia coli, GI1787432, Length=426, Percent_Identity=41.3145539906103, Blast_Score=319, Evalue=3e-88,
Organism=Escherichia coli, GI1786425, Length=219, Percent_Identity=26.4840182648402, Blast_Score=70, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017961
- InterPro:   IPR001126
- InterPro:   IPR017963 [H]

Pfam domain/function: PF00817 IMS [H]

EC number: NA

Molecular weight: Translated: 46874; Mature: 46874

Theoretical pI: Translated: 9.69; Mature: 9.69

Prosite motif: PS50173 UMUC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.1 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
3.1 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYALVDANSFYCSAEQVFRPDWRGKPIIVLSNNDGCIVAANRQARELGIPKFAPYFHVKE
CEEEEECCCCEECHHHHCCCCCCCCEEEEEECCCCEEEECCCCHHHCCCCCCCCHHHHHH
QCAKLGVIVCSSNYELYADLSAKMMEIIGRFAPDQHIYSIDESFLSFKHCHTSIPCLKTH
HHHHCCEEEECCCCEEEECHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCHHHC
GLRIRQTVWKEARIPVCVGIGATLTLAKIANHAAKKLPGYHGVCLIDNEPQRIEILKQLL
CCHHHHHHHHHCCCCEEECCCHHHHHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHH
VSDVWGIGRRLSKKLVSMGIHTAYDLAQMPTGLARKQFSIEIERTVRELNGTACKQWDHT
HHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCHHHHHHEEHHHHHHHHHCCCHHHCCCCC
RADKQQIFSTRSVGERIMDFEALLQALSKHVGIAAAKARAQGSCCKSMLIFANNSPYDEQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHEEEEEECCCCCCCC
PVGFKSLIHFPTATNCTIEMTQAASLAAPRLFRPGVKYYKIGIGLINLEQNRYQQLDLFN
CCCHHHHEECCCCCCCEEEEECHHHHCCCHHHCCCCEEEEEEEEEEEECCCHHHHCCEEE
LSKTKPTLMNAFDGINARYGRDTLFLAAQGIEQKWAMRRALLTPQYTTLWGGIPRVKC
CCCCCCHHHHHHCCCCCCCCCCEEEEEECCHHHHHHHHHHHCCCCHHHHHCCCCCCCC
>Mature Secondary Structure
MYALVDANSFYCSAEQVFRPDWRGKPIIVLSNNDGCIVAANRQARELGIPKFAPYFHVKE
CEEEEECCCCEECHHHHCCCCCCCCEEEEEECCCCEEEECCCCHHHCCCCCCCCHHHHHH
QCAKLGVIVCSSNYELYADLSAKMMEIIGRFAPDQHIYSIDESFLSFKHCHTSIPCLKTH
HHHHCCEEEECCCCEEEECHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCHHHC
GLRIRQTVWKEARIPVCVGIGATLTLAKIANHAAKKLPGYHGVCLIDNEPQRIEILKQLL
CCHHHHHHHHHCCCCEEECCCHHHHHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHH
VSDVWGIGRRLSKKLVSMGIHTAYDLAQMPTGLARKQFSIEIERTVRELNGTACKQWDHT
HHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCHHHHHHEEHHHHHHHHHCCCHHHCCCCC
RADKQQIFSTRSVGERIMDFEALLQALSKHVGIAAAKARAQGSCCKSMLIFANNSPYDEQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHEEEEEECCCCCCCC
PVGFKSLIHFPTATNCTIEMTQAASLAAPRLFRPGVKYYKIGIGLINLEQNRYQQLDLFN
CCCHHHHEECCCCCCCEEEEECHHHHCCCHHHCCCCEEEEEEEEEEEECCCHHHHCCEEE
LSKTKPTLMNAFDGINARYGRDTLFLAAQGIEQKWAMRRALLTPQYTTLWGGIPRVKC
CCCCCCHHHHHHCCCCCCCCCCEEEEEECCHHHHHHHHHHHCCCCHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Serine endopeptidases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2144275; 2203737; 11677609 [H]