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The map label for this gene is apr [H]

Identifier: 117920187

GI number: 117920187

Start: 2051257

End: 2055042

Strand: Direct

Name: apr [H]

Synonym: Shewana3_1740

Alternate gene names: 117920187

Gene position: 2051257-2055042 (Clockwise)

Preceding gene: 117920186

Following gene: 117920190

Centisome position: 41.25

GC content: 50.74

Gene sequence:

>3786_bases
ATGAAACAACTCTTTAAGCGCAGCCGTATTGCTGCGACCTGTCTTATGGCAATGGGGCTCGCGACCAGTTACGCCACACT
GGCGGATGATAGCGCGTTCGTGGATGCACAGTCTGGTGCGGTGCAATTTACCTTAATTACCGGTGAGGTGGTCACAGCAG
TCGTGCGTGCTGATGGCTCACTCGGCGGGATCCGTTTGCTCGGTGAACATGGGGCCGAGGTGATCACCAGTATTTTTCAA
AATGCGAATGGCCAATATCTTATTACACCCAAAGCCCAACCTCTGGTGACATCCCAAGCCGTCGATTTAGAGCTTTTTAA
CATCACTAAATTACATGCAGCGGGCTATGACGATGCTTCCACCGATAAGCTGCCCGTGATTATCGAATACCAAGATGGCA
CGCTGGCGGGCTCTGCGGTACCGAATCCGATTGAAGGGGCGACATTAACCGATGAAATTGAGCTTATCGACAGCGCCGCC
TTTGGTGTGAGTAAGTCGAAAGCGGCCAAGGTATGGGAAACTCTCAGCACGGATGCTTCGGTGAAATCTGTATGGTTAGA
TGCCGTGGTGCATGCCGATAAAGAGGTGCCAAATGGCGTGAATGCCTTGGCAAACTTAACCCCAACCGTGCCGTTAACCG
GTACCTATGGCAATTTAGCCAAGCACTTCAATGGTCAAGGTGTCACTGTTGCAGTACTTGATACTGGTTATGATCTTGAT
CATAACGATTTAGCAGAGCAAGTGCTTGTCAGTAAAGATTTTACCTATTCCAGTAATGGGATAGACGATCTCAATGGCCA
CGGCACTCATACTGCGGCCACCATTGCAGGCACAGGTGTCGAATCTAATGGTCGCTGGGCGGGCATGGCGCCAGGAGCTA
AGTTGCTGGTGGGCAAGGTGCTGACAAATGCGGGCTCCGGCTCTACTAGTGGGATCTTGAGTGGTATGCAGTGGGCCGTG
GCTCAAGGCGCCGATGTGGTCAGCATGTCTTTAGGTGGTAGTGGCACTAGCTGTACTGGGCCGCTTGTCGATATGGTCGA
AGCCTTGAGTGACAAAGCCTTGTTTGTGGTGTCGGCGGGCAATAGTTTTACCCGCGAGACGGTGGGGATCCCAGGATGTG
CCCCGAGTGCGTTAACTGTGGGAGCCGTTGACCGCGATAATCACACTGCATCTTTCTCATCCCGTGGACCCTCTCCTGAT
GGTCATTCTGCAAAACCCGATATCGCCTCACAAGGTGTGGATGTCGTGTCGGCAGCTTCTGGGGGATTTGGCTCGACGGC
CTATCGCGCTCTGTCGGGTACCTCCATGTCGGCGCCCCATGTGTCAGGCGGCGCGGCGATTGTGATGCAAGCCAGACCCG
AATTGAGTCCGCGGCAAGTGAAAGAAGTGTTGACCTCTTCGGTATTACCGAACGATTCACACGTGCTTGAGCAGGGAGCT
GGGCCTATGGATGTGAATCGCGCAATCGCTCAAAGCATTATCGCGCCGCCCAATATGGAGCTTGGCTCCTTTGCCTATGA
TCAGGATATTGGCGTTACAGAAAAAACCATTAGTTTGCGCAACTTATCTGACAAGGACATCAATCTTAAGCTGAAAATGA
GCTTGATAGGTGAAGATGGTAAAACCCGTATGCCAGCCACACTAGCGGGATTAAGCCTTAACAGTATTACCGTCCCTGCT
AAGGGGAGTGCTGAGATCCCTGTGTGGATAGACTCGAGTGTGGCACTGCGTAGTGGCGCCTATGGCACTATCACTGGGCG
CATCGAAGGTACAACAACGGGTAAATCCGATGAACGGGTCACTGTACCTGTGTCGTTTTGGATTGAGCCGCCGCAGGTAA
ACTTGAGCTTAAGTGTGACCGATATGCGTGGTCATCCTGCCACCTCGCCATCAAAAGTGTATTTGATGAATGAGGAAGAT
GATTGGGGACAAGCCGTAAGCTTAACCAATGGCCAAGCGAGCGTGAAAGTGCCTGAGGGTAACTATTCAATCGTCGCTAA
TGTTATGACCTATGACAATGATTTTACTTCAAATGGTTTAGTGGAATCGGCGACACAAATGGCGGTGCTTAATCGCAAGT
TAAGCCAAGATACCCACCTTGAGTTTGATGCCCGTAATGCTGAAAAACTGCAGTTTAAAGCCAGCAAGCCGTTAGCGACG
CAAGGTTTCTCCTTTGGATTTACCTACGCATTGGATGATAACAAGCTCGCAAAATTGGCGGCGATGGACTTTGCACCTGA
CTATGTGAAGGATATGTACACTTGGTCACAGGGGCACGATGACAGATTCCGCTCCTTCGTGACGACTCGTGCTATTGCCC
CCGAAGCTGTGCTGACGATGCAAAATGGGGAAGTGCTGGAGTATAACAAGCAAGGTTTGGCAATGTCCTTCAATGGCCAA
GGCCGAGCAGAAGTGGTATTTGTGGGCGATGGCGGTTACAGCACGGATTGGACTCAGTTCGATCTTAAGGGACGCATTGC
ACTCATAGGCAATCCCTATTATTTGACCTCCACCATGGTGAACAATGCCCTGAAAAATGGCGCGATTGGGGTGATTTTCT
ATCGTCCTGGTCTTAAGGGGCGTTACAAGGGAACGATTGGTGGCACGCCGCGCATTCCTGCTGTAGGGATCAGTTCAGAT
CAAGGTGAAGCCCTATTGGCGCAGGTCGAAGCGGGCAACAATCTGGTGAGTTGGTCAGGAATTGCCGCTGAGCGTACACC
CTATGCTTATTCCATTAACCATATCACTGACGGGCGTATCGATGGTGGGCAAGTGGTGCTGCAAGAGCACAAGATGCAGA
AAATTAGTGCGGCCTATCATTCACAAAATGATGAACGTCCTGTGTTTGTGGATGTGATGGGGATGACCAATAGTACGGGC
GAGTTCTATTCCACGGGCAGCACGCAAATGGTGATGACACCGATAATCCGTGATGAATACTACACGGCAACCCGTAAAAA
TATGTGGACCAACATCGTTATGCCCGGCTCTGCGATGACGGCCGAAGGCGCTTACTTCGATGGTCCACGTATGATGACCG
AAGGCACCGTTGAGAGCACCTCTTGGCTTAAAGGACCTAAGGCGGGTAGTTTGCTCACTAATGGTGGTGCGATTGCCTAT
CGCGACACTAATACTATCGATTTAAGTATTGTGCGATTCGGTGATGCGGCAGGGCATGATGGCAAAGGTGGCTACAATTC
ACAGTCTCTCTATGGGTTGAAAGTGAATGGTCAGAACACTTATCTCGACAGTGGGCTGCTGACGCTTCCTGACTCGAATG
CTCAAGTAGAGCTCGAAATTCGCTCCTACGCCCGAGGTGTCGGTAGCAGCTCGCCGATTAAAGATAACTTAGGCTCTTTC
TACCAAGGGATTTATCACTTCAGCACGGATTCGAGTAAGCAAGGTGTTCAGGCGGTATTGGTACCTAAAATTGATATCCC
TATCGCGCTTGATAACACTGTGGCTGCGGGTGAAGCGGTTACCGTCAAGCTTGCGGGTGTGATGGATGGCATAGGTCAAG
TTGACTTGGCTGATGTCAGCTTAGAGTACGGTTATGGCCAAGAGTGTTCTCTGGCAGCAGTCTCTGTATCGATTTACTGC
CCCGTAGCGAGTAAATTTGCTGAAAGTGCATGGAAAACGGCAGAAGTCAAAATGGTCGATGGTCAGTGGGTTGCGACCAT
TCCTAATGATACTGCCGCGGGTAATTTTGTGCATTTACGTGTACAAATGAATGATGGCAGTAGCACTGCGCAGCAGACTA
TGATGCGGGTTTATATGCTGAAGTAA

Upstream 100 bases:

>100_bases
CATCTTGTTGCACTGGAAGCTTGCATTCCAACACAAAAACCATTGCTCAGATTGGTTTGTCGACTGAGCAATTACAAGGT
GATTTTTCAGGGAACATGAA

Downstream 100 bases:

>100_bases
TACGTCAGAGTAGTTTGGATTACACCGCTATTGTTTAGGCAATAGCGGTTTTTTATTACTGAATTTTTAACATCGGCTTA
GAAAGGGAAGAGCACGGCAA

Product: peptidase S8/S53 subtilisin kexin sedolisin

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 1261; Mature: 1261

Protein sequence:

>1261_residues
MKQLFKRSRIAATCLMAMGLATSYATLADDSAFVDAQSGAVQFTLITGEVVTAVVRADGSLGGIRLLGEHGAEVITSIFQ
NANGQYLITPKAQPLVTSQAVDLELFNITKLHAAGYDDASTDKLPVIIEYQDGTLAGSAVPNPIEGATLTDEIELIDSAA
FGVSKSKAAKVWETLSTDASVKSVWLDAVVHADKEVPNGVNALANLTPTVPLTGTYGNLAKHFNGQGVTVAVLDTGYDLD
HNDLAEQVLVSKDFTYSSNGIDDLNGHGTHTAATIAGTGVESNGRWAGMAPGAKLLVGKVLTNAGSGSTSGILSGMQWAV
AQGADVVSMSLGGSGTSCTGPLVDMVEALSDKALFVVSAGNSFTRETVGIPGCAPSALTVGAVDRDNHTASFSSRGPSPD
GHSAKPDIASQGVDVVSAASGGFGSTAYRALSGTSMSAPHVSGGAAIVMQARPELSPRQVKEVLTSSVLPNDSHVLEQGA
GPMDVNRAIAQSIIAPPNMELGSFAYDQDIGVTEKTISLRNLSDKDINLKLKMSLIGEDGKTRMPATLAGLSLNSITVPA
KGSAEIPVWIDSSVALRSGAYGTITGRIEGTTTGKSDERVTVPVSFWIEPPQVNLSLSVTDMRGHPATSPSKVYLMNEED
DWGQAVSLTNGQASVKVPEGNYSIVANVMTYDNDFTSNGLVESATQMAVLNRKLSQDTHLEFDARNAEKLQFKASKPLAT
QGFSFGFTYALDDNKLAKLAAMDFAPDYVKDMYTWSQGHDDRFRSFVTTRAIAPEAVLTMQNGEVLEYNKQGLAMSFNGQ
GRAEVVFVGDGGYSTDWTQFDLKGRIALIGNPYYLTSTMVNNALKNGAIGVIFYRPGLKGRYKGTIGGTPRIPAVGISSD
QGEALLAQVEAGNNLVSWSGIAAERTPYAYSINHITDGRIDGGQVVLQEHKMQKISAAYHSQNDERPVFVDVMGMTNSTG
EFYSTGSTQMVMTPIIRDEYYTATRKNMWTNIVMPGSAMTAEGAYFDGPRMMTEGTVESTSWLKGPKAGSLLTNGGAIAY
RDTNTIDLSIVRFGDAAGHDGKGGYNSQSLYGLKVNGQNTYLDSGLLTLPDSNAQVELEIRSYARGVGSSSPIKDNLGSF
YQGIYHFSTDSSKQGVQAVLVPKIDIPIALDNTVAAGEAVTVKLAGVMDGIGQVDLADVSLEYGYGQECSLAAVSVSIYC
PVASKFAESAWKTAEVKMVDGQWVATIPNDTAAGNFVHLRVQMNDGSSTAQQTMMRVYMLK

Sequences:

>Translated_1261_residues
MKQLFKRSRIAATCLMAMGLATSYATLADDSAFVDAQSGAVQFTLITGEVVTAVVRADGSLGGIRLLGEHGAEVITSIFQ
NANGQYLITPKAQPLVTSQAVDLELFNITKLHAAGYDDASTDKLPVIIEYQDGTLAGSAVPNPIEGATLTDEIELIDSAA
FGVSKSKAAKVWETLSTDASVKSVWLDAVVHADKEVPNGVNALANLTPTVPLTGTYGNLAKHFNGQGVTVAVLDTGYDLD
HNDLAEQVLVSKDFTYSSNGIDDLNGHGTHTAATIAGTGVESNGRWAGMAPGAKLLVGKVLTNAGSGSTSGILSGMQWAV
AQGADVVSMSLGGSGTSCTGPLVDMVEALSDKALFVVSAGNSFTRETVGIPGCAPSALTVGAVDRDNHTASFSSRGPSPD
GHSAKPDIASQGVDVVSAASGGFGSTAYRALSGTSMSAPHVSGGAAIVMQARPELSPRQVKEVLTSSVLPNDSHVLEQGA
GPMDVNRAIAQSIIAPPNMELGSFAYDQDIGVTEKTISLRNLSDKDINLKLKMSLIGEDGKTRMPATLAGLSLNSITVPA
KGSAEIPVWIDSSVALRSGAYGTITGRIEGTTTGKSDERVTVPVSFWIEPPQVNLSLSVTDMRGHPATSPSKVYLMNEED
DWGQAVSLTNGQASVKVPEGNYSIVANVMTYDNDFTSNGLVESATQMAVLNRKLSQDTHLEFDARNAEKLQFKASKPLAT
QGFSFGFTYALDDNKLAKLAAMDFAPDYVKDMYTWSQGHDDRFRSFVTTRAIAPEAVLTMQNGEVLEYNKQGLAMSFNGQ
GRAEVVFVGDGGYSTDWTQFDLKGRIALIGNPYYLTSTMVNNALKNGAIGVIFYRPGLKGRYKGTIGGTPRIPAVGISSD
QGEALLAQVEAGNNLVSWSGIAAERTPYAYSINHITDGRIDGGQVVLQEHKMQKISAAYHSQNDERPVFVDVMGMTNSTG
EFYSTGSTQMVMTPIIRDEYYTATRKNMWTNIVMPGSAMTAEGAYFDGPRMMTEGTVESTSWLKGPKAGSLLTNGGAIAY
RDTNTIDLSIVRFGDAAGHDGKGGYNSQSLYGLKVNGQNTYLDSGLLTLPDSNAQVELEIRSYARGVGSSSPIKDNLGSF
YQGIYHFSTDSSKQGVQAVLVPKIDIPIALDNTVAAGEAVTVKLAGVMDGIGQVDLADVSLEYGYGQECSLAAVSVSIYC
PVASKFAESAWKTAEVKMVDGQWVATIPNDTAAGNFVHLRVQMNDGSSTAQQTMMRVYMLK
>Mature_1261_residues
MKQLFKRSRIAATCLMAMGLATSYATLADDSAFVDAQSGAVQFTLITGEVVTAVVRADGSLGGIRLLGEHGAEVITSIFQ
NANGQYLITPKAQPLVTSQAVDLELFNITKLHAAGYDDASTDKLPVIIEYQDGTLAGSAVPNPIEGATLTDEIELIDSAA
FGVSKSKAAKVWETLSTDASVKSVWLDAVVHADKEVPNGVNALANLTPTVPLTGTYGNLAKHFNGQGVTVAVLDTGYDLD
HNDLAEQVLVSKDFTYSSNGIDDLNGHGTHTAATIAGTGVESNGRWAGMAPGAKLLVGKVLTNAGSGSTSGILSGMQWAV
AQGADVVSMSLGGSGTSCTGPLVDMVEALSDKALFVVSAGNSFTRETVGIPGCAPSALTVGAVDRDNHTASFSSRGPSPD
GHSAKPDIASQGVDVVSAASGGFGSTAYRALSGTSMSAPHVSGGAAIVMQARPELSPRQVKEVLTSSVLPNDSHVLEQGA
GPMDVNRAIAQSIIAPPNMELGSFAYDQDIGVTEKTISLRNLSDKDINLKLKMSLIGEDGKTRMPATLAGLSLNSITVPA
KGSAEIPVWIDSSVALRSGAYGTITGRIEGTTTGKSDERVTVPVSFWIEPPQVNLSLSVTDMRGHPATSPSKVYLMNEED
DWGQAVSLTNGQASVKVPEGNYSIVANVMTYDNDFTSNGLVESATQMAVLNRKLSQDTHLEFDARNAEKLQFKASKPLAT
QGFSFGFTYALDDNKLAKLAAMDFAPDYVKDMYTWSQGHDDRFRSFVTTRAIAPEAVLTMQNGEVLEYNKQGLAMSFNGQ
GRAEVVFVGDGGYSTDWTQFDLKGRIALIGNPYYLTSTMVNNALKNGAIGVIFYRPGLKGRYKGTIGGTPRIPAVGISSD
QGEALLAQVEAGNNLVSWSGIAAERTPYAYSINHITDGRIDGGQVVLQEHKMQKISAAYHSQNDERPVFVDVMGMTNSTG
EFYSTGSTQMVMTPIIRDEYYTATRKNMWTNIVMPGSAMTAEGAYFDGPRMMTEGTVESTSWLKGPKAGSLLTNGGAIAY
RDTNTIDLSIVRFGDAAGHDGKGGYNSQSLYGLKVNGQNTYLDSGLLTLPDSNAQVELEIRSYARGVGSSSPIKDNLGSF
YQGIYHFSTDSSKQGVQAVLVPKIDIPIALDNTVAAGEAVTVKLAGVMDGIGQVDLADVSLEYGYGQECSLAAVSVSIYC
PVASKFAESAWKTAEVKMVDGQWVATIPNDTAAGNFVHLRVQMNDGSSTAQQTMMRVYMLK

Specific function: Subtilisin is an extracellular alkaline serine protease, it catalyzes the hydrolysis of proteins and peptide amides [H]

COG id: COG1404

COG function: function code O; Subtilisin-like serine proteases

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S8 family [H]

Homologues:

Organism=Homo sapiens, GI4506775, Length=304, Percent_Identity=32.5657894736842, Blast_Score=101, Evalue=4e-21,
Organism=Saccharomyces cerevisiae, GI6319893, Length=261, Percent_Identity=32.9501915708812, Blast_Score=100, Evalue=3e-21,
Organism=Saccharomyces cerevisiae, GI6320775, Length=266, Percent_Identity=31.203007518797, Blast_Score=93, Evalue=3e-19,
Organism=Saccharomyces cerevisiae, GI6324576, Length=262, Percent_Identity=29.0076335877863, Blast_Score=82, Evalue=4e-16,
Organism=Drosophila melanogaster, GI45550681, Length=292, Percent_Identity=30.8219178082192, Blast_Score=102, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000209
- InterPro:   IPR022398
- InterPro:   IPR015500
- InterPro:   IPR009020
- InterPro:   IPR010259 [H]

Pfam domain/function: PF05922 Inhibitor_I9; PF00082 Peptidase_S8 [H]

EC number: =3.4.21.62 [H]

Molecular weight: Translated: 133221; Mature: 133221

Theoretical pI: Translated: 4.83; Mature: 4.83

Prosite motif: PS00138 SUBTILASE_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQLFKRSRIAATCLMAMGLATSYATLADDSAFVDAQSGAVQFTLITGEVVTAVVRADGS
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCEEEEEEEEHHHEEEEECCCCC
LGGIRLLGEHGAEVITSIFQNANGQYLITPKAQPLVTSQAVDLELFNITKLHAAGYDDAS
CCCEEEECCCCHHHHHHHHHCCCCCEEECCCCCCEEECCEEEEEEEEEEEEEECCCCCCC
TDKLPVIIEYQDGTLAGSAVPNPIEGATLTDEIELIDSAAFGVSKSKAAKVWETLSTDAS
CCCCEEEEEECCCEEECCCCCCCCCCCEECHHHHHHHHHHCCCCCHHHHHHHHHHCCCCH
VKSVWLDAVVHADKEVPNGVNALANLTPTVPLTGTYGNLAKHFNGQGVTVAVLDTGYDLD
HHHHHHHHHHHCCCCCCCHHHHHHCCCCCCEECCCCHHHHHHCCCCCEEEEEEECCCCCC
HNDLAEQVLVSKDFTYSSNGIDDLNGHGTHTAATIAGTGVESNGRWAGMAPGAKLLVGKV
HHHHHHHHHHHCCCEECCCCCCCCCCCCCEEEEEEEECCCCCCCEEEECCCCHHHHHHHH
LTNAGSGSTSGILSGMQWAVAQGADVVSMSLGGSGTSCTGPLVDMVEALSDKALFVVSAG
HHCCCCCCCHHHHHCHHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHHCCCCEEEEEECC
NSFTRETVGIPGCAPSALTVGAVDRDNHTASFSSRGPSPDGHSAKPDIASQGVDVVSAAS
CCCCHHHCCCCCCCCCCEEEEEECCCCCCEECCCCCCCCCCCCCCCCHHHCCCCEEEECC
GGFGSTAYRALSGTSMSAPHVSGGAAIVMQARPELSPRQVKEVLTSSVLPNDSHVLEQGA
CCCCHHHHHEECCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHCCCCCHHHHHCCC
GPMDVNRAIAQSIIAPPNMELGSFAYDQDIGVTEKTISLRNLSDKDINLKLKMSLIGEDG
CCCHHHHHHHHHHCCCCCCCCCCEEECCCCCCEEEEEEEECCCCCCEEEEEEEEEECCCC
KTRMPATLAGLSLNSITVPAKGSAEIPVWIDSSVALRSGAYGTITGRIEGTTTGKSDERV
CCCCCEEEECCEECEEEECCCCCCCEEEEECCCEEECCCCCEEEEEEEEECCCCCCCCEE
TVPVSFWIEPPQVNLSLSVTDMRGHPATSPSKVYLMNEEDDWGQAVSLTNGQASVKVPEG
EEEEEEEECCCCEEEEEEEEECCCCCCCCCCEEEEECCCCCCCCEEEEECCCEEEEECCC
NYSIVANVMTYDNDFTSNGLVESATQMAVLNRKLSQDTHLEFDARNAEKLQFKASKPLAT
CEEEEEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEECCCCEEEEEECCCCCCC
QGFSFGFTYALDDNKLAKLAAMDFAPDYVKDMYTWSQGHDDRFRSFVTTRAIAPEAVLTM
CCCCCEEEEEECCCCEEEEEECCCCHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCEEEEE
QNGEVLEYNKQGLAMSFNGQGRAEVVFVGDGGYSTDWTQFDLKGRIALIGNPYYLTSTMV
CCCCEEEECCCCEEEEECCCCCEEEEEEECCCCCCCCEEEECCEEEEEEECCEEEEHHHH
NNALKNGAIGVIFYRPGLKGRYKGTIGGTPRIPAVGISSDQGEALLAQVEAGNNLVSWSG
HHHHCCCCEEEEEECCCCCCCEEECCCCCCCCCEEECCCCCCCEEEEEEECCCCEEEECC
IAAERTPYAYSINHITDGRIDGGQVVLQEHKMQKISAAYHSQNDERPVFVDVMGMTNSTG
CCCCCCCCEEEECCCCCCCCCCCEEEEEHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCC
EFYSTGSTQMVMTPIIRDEYYTATRKNMWTNIVMPGSAMTAEGAYFDGPRMMTEGTVEST
CEEECCCCEEEEEEECCCCHHHHHHCCCEEEEEECCCCCCCCCCEECCCEEEECCCCCCC
SWLKGPKAGSLLTNGGAIAYRDTNTIDLSIVRFGDAAGHDGKGGYNSQSLYGLKVNGQNT
HHCCCCCCCCEEECCCEEEEECCCEEEEEEEEECCCCCCCCCCCCCCCEEEEEEECCCCE
YLDSGLLTLPDSNAQVELEIRSYARGVGSSSPIKDNLGSFYQGIYHFSTDSSKQGVQAVL
EECCCEEECCCCCCEEEEEEHHHHCCCCCCCCCHHHHHHHHHHHEEECCCCCCCCCEEEE
VPKIDIPIALDNTVAAGEAVTVKLAGVMDGIGQVDLADVSLEYGYGQECSLAAVSVSIYC
EEECCCEEEECCCCCCCCEEEEEEEEHHCCCCCEEEEEEEEECCCCCCCEEEEEEEEEEE
PVASKFAESAWKTAEVKMVDGQWVATIPNDTAAGNFVHLRVQMNDGSSTAQQTMMRVYML
CCHHHHHHHHCCEEEEEEECCCEEEECCCCCCCCCEEEEEEEECCCCHHHHHHHHHHEEC
K
C
>Mature Secondary Structure
MKQLFKRSRIAATCLMAMGLATSYATLADDSAFVDAQSGAVQFTLITGEVVTAVVRADGS
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCEEEEEEEEHHHEEEEECCCCC
LGGIRLLGEHGAEVITSIFQNANGQYLITPKAQPLVTSQAVDLELFNITKLHAAGYDDAS
CCCEEEECCCCHHHHHHHHHCCCCCEEECCCCCCEEECCEEEEEEEEEEEEEECCCCCCC
TDKLPVIIEYQDGTLAGSAVPNPIEGATLTDEIELIDSAAFGVSKSKAAKVWETLSTDAS
CCCCEEEEEECCCEEECCCCCCCCCCCEECHHHHHHHHHHCCCCCHHHHHHHHHHCCCCH
VKSVWLDAVVHADKEVPNGVNALANLTPTVPLTGTYGNLAKHFNGQGVTVAVLDTGYDLD
HHHHHHHHHHHCCCCCCCHHHHHHCCCCCCEECCCCHHHHHHCCCCCEEEEEEECCCCCC
HNDLAEQVLVSKDFTYSSNGIDDLNGHGTHTAATIAGTGVESNGRWAGMAPGAKLLVGKV
HHHHHHHHHHHCCCEECCCCCCCCCCCCCEEEEEEEECCCCCCCEEEECCCCHHHHHHHH
LTNAGSGSTSGILSGMQWAVAQGADVVSMSLGGSGTSCTGPLVDMVEALSDKALFVVSAG
HHCCCCCCCHHHHHCHHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHHCCCCEEEEEECC
NSFTRETVGIPGCAPSALTVGAVDRDNHTASFSSRGPSPDGHSAKPDIASQGVDVVSAAS
CCCCHHHCCCCCCCCCCEEEEEECCCCCCEECCCCCCCCCCCCCCCCHHHCCCCEEEECC
GGFGSTAYRALSGTSMSAPHVSGGAAIVMQARPELSPRQVKEVLTSSVLPNDSHVLEQGA
CCCCHHHHHEECCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHCCCCCHHHHHCCC
GPMDVNRAIAQSIIAPPNMELGSFAYDQDIGVTEKTISLRNLSDKDINLKLKMSLIGEDG
CCCHHHHHHHHHHCCCCCCCCCCEEECCCCCCEEEEEEEECCCCCCEEEEEEEEEECCCC
KTRMPATLAGLSLNSITVPAKGSAEIPVWIDSSVALRSGAYGTITGRIEGTTTGKSDERV
CCCCCEEEECCEECEEEECCCCCCCEEEEECCCEEECCCCCEEEEEEEEECCCCCCCCEE
TVPVSFWIEPPQVNLSLSVTDMRGHPATSPSKVYLMNEEDDWGQAVSLTNGQASVKVPEG
EEEEEEEECCCCEEEEEEEEECCCCCCCCCCEEEEECCCCCCCCEEEEECCCEEEEECCC
NYSIVANVMTYDNDFTSNGLVESATQMAVLNRKLSQDTHLEFDARNAEKLQFKASKPLAT
CEEEEEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEECCCCEEEEEECCCCCCC
QGFSFGFTYALDDNKLAKLAAMDFAPDYVKDMYTWSQGHDDRFRSFVTTRAIAPEAVLTM
CCCCCEEEEEECCCCEEEEEECCCCHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCEEEEE
QNGEVLEYNKQGLAMSFNGQGRAEVVFVGDGGYSTDWTQFDLKGRIALIGNPYYLTSTMV
CCCCEEEECCCCEEEEECCCCCEEEEEEECCCCCCCCEEEECCEEEEEEECCEEEEHHHH
NNALKNGAIGVIFYRPGLKGRYKGTIGGTPRIPAVGISSDQGEALLAQVEAGNNLVSWSG
HHHHCCCCEEEEEECCCCCCCEEECCCCCCCCCEEECCCCCCCEEEEEEECCCCEEEECC
IAAERTPYAYSINHITDGRIDGGQVVLQEHKMQKISAAYHSQNDERPVFVDVMGMTNSTG
CCCCCCCCEEEECCCCCCCCCCCEEEEEHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCC
EFYSTGSTQMVMTPIIRDEYYTATRKNMWTNIVMPGSAMTAEGAYFDGPRMMTEGTVEST
CEEECCCCEEEEEEECCCCHHHHHHCCCEEEEEECCCCCCCCCCEECCCEEEECCCCCCC
SWLKGPKAGSLLTNGGAIAYRDTNTIDLSIVRFGDAAGHDGKGGYNSQSLYGLKVNGQNT
HHCCCCCCCCEEECCCEEEEECCCEEEEEEEEECCCCCCCCCCCCCCCEEEEEEECCCCE
YLDSGLLTLPDSNAQVELEIRSYARGVGSSSPIKDNLGSFYQGIYHFSTDSSKQGVQAVL
EECCCEEECCCCCCEEEEEEHHHHCCCCCCCCCHHHHHHHHHHHEEECCCCCCCCCEEEE
VPKIDIPIALDNTVAAGEAVTVKLAGVMDGIGQVDLADVSLEYGYGQECSLAAVSVSIYC
EEECCCEEEECCCCCCCCEEEEEEEEHHCCCCCEEEEEEEEECCCCCCCEEEEEEEEEEE
PVASKFAESAWKTAEVKMVDGQWVATIPNDTAAGNFVHLRVQMNDGSSTAQQTMMRVYML
CCHHHHHHHHCCEEEEEEECCCEEEECCCCCCCCCEEEEEEEECCCCHHHHHHHHHHEEC
K
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3001653; 4967581; 8512925; 9425066 [H]