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The map label for this gene is sucD [H]

Identifier: 117920160

GI number: 117920160

Start: 2017998

End: 2018870

Strand: Direct

Name: sucD [H]

Synonym: Shewana3_1713

Alternate gene names: 117920160

Gene position: 2017998-2018870 (Clockwise)

Preceding gene: 117920159

Following gene: 117920161

Centisome position: 40.59

GC content: 48.11

Gene sequence:

>873_bases
ATGTCTGTATTAATTAACAAAGATACCAAGGTAATCTGCCAAGGCTTTACCGGTGGTCAAGGTACTTTCCACTCTCAACA
AGCTATCGATTACGGTACGCAAATGGTTGGTGGTGTATCTCCAGGTAAAGGCGGTACTGAGCACTTAGGTCTGCCAGTGT
TCAACACTGTGAAAGACGCTGTGGCTGCGACTGGCGCAACTGCTTCTGTTATCTACGTTCCTGCTCCTTTCTGTAAAGAT
GCAATCCTTGAAGCAATCGACGGTGGTATCGAGCTGATCGTATGTATCACTGAAGGTATCCCAACACTGGATATGCTGGA
AGTGAAAGTGAAGCTAGAAGAAACTGGCGTTCGCATGATCGGTCCTAACTGCCCAGGTGTTATCACTCCAGGTGAATGTA
AGATTGGTATTATGCCAGGCCACATCCACTTAAAAGGAAAAGTGGGTATCGTTTCTCGTTCAGGTACGCTGACCTATGAA
GCGGTTAAGCAAACTACTGACGAAGGTTTCGGCCAATCTACTTGCGTAGGTATTGGTGGTGACCCAATCCCAGGTACTAA
CTTCATCGACGTATTGGAAATGTTCCAAAACGATCCACAGACTGAAGCCATCGTGATGATCGGTGAAATCGGTGGTACTG
CTGAAGAAGAAGCGGCGGCTTACATCAAAGCTAACGTGACTAAACCAGTTGTGTCTTACATCGCGGGTGTAACTGCTCCT
GCTGGTAAGCGTATGGGTCACGCGGGTGCGATCATTGCTGGCGGTAAAGGTACTGCTGCTGACAAATTTGCTGCATTAGA
AGCAGCGGGCGTGACAACTGTCCGTTCGTTAGCGGATATCGGCAAAGCGCTGCGTGCTAAAACGGGTTGGTAA

Upstream 100 bases:

>100_bases
TAGGCCGTGAAGTATTAGCTAAATCAGGTCTTGATATCATTGCAGCTAACAGTCTGACTGATGCGGCTGAGCAAGTAGTT
AAAGCTGCGGAGGGCAAATA

Downstream 100 bases:

>100_bases
TCTAACCGTTAACACACGAAAAGGCGCCTAAGGCGCCTTTTTTATTGCGTGTCTGTTAGCGAGTGCTGAGCAGTAAAGTG
TGAGAATGGGCAAAGCTAAC

Product: succinyl-CoA synthetase (ADP-forming) subunit alpha

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit alpha; SCS-alpha [H]

Number of amino acids: Translated: 290; Mature: 289

Protein sequence:

>290_residues
MSVLINKDTKVICQGFTGGQGTFHSQQAIDYGTQMVGGVSPGKGGTEHLGLPVFNTVKDAVAATGATASVIYVPAPFCKD
AILEAIDGGIELIVCITEGIPTLDMLEVKVKLEETGVRMIGPNCPGVITPGECKIGIMPGHIHLKGKVGIVSRSGTLTYE
AVKQTTDEGFGQSTCVGIGGDPIPGTNFIDVLEMFQNDPQTEAIVMIGEIGGTAEEEAAAYIKANVTKPVVSYIAGVTAP
AGKRMGHAGAIIAGGKGTAADKFAALEAAGVTTVRSLADIGKALRAKTGW

Sequences:

>Translated_290_residues
MSVLINKDTKVICQGFTGGQGTFHSQQAIDYGTQMVGGVSPGKGGTEHLGLPVFNTVKDAVAATGATASVIYVPAPFCKD
AILEAIDGGIELIVCITEGIPTLDMLEVKVKLEETGVRMIGPNCPGVITPGECKIGIMPGHIHLKGKVGIVSRSGTLTYE
AVKQTTDEGFGQSTCVGIGGDPIPGTNFIDVLEMFQNDPQTEAIVMIGEIGGTAEEEAAAYIKANVTKPVVSYIAGVTAP
AGKRMGHAGAIIAGGKGTAADKFAALEAAGVTTVRSLADIGKALRAKTGW
>Mature_289_residues
SVLINKDTKVICQGFTGGQGTFHSQQAIDYGTQMVGGVSPGKGGTEHLGLPVFNTVKDAVAATGATASVIYVPAPFCKDA
ILEAIDGGIELIVCITEGIPTLDMLEVKVKLEETGVRMIGPNCPGVITPGECKIGIMPGHIHLKGKVGIVSRSGTLTYEA
VKQTTDEGFGQSTCVGIGGDPIPGTNFIDVLEMFQNDPQTEAIVMIGEIGGTAEEEAAAYIKANVTKPVVSYIAGVTAPA
GKRMGHAGAIIAGGKGTAADKFAALEAAGVTTVRSLADIGKALRAKTGW

Specific function: Unknown

COG id: COG0074

COG function: function code C; Succinyl-CoA synthetase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the succinate/malate CoA ligase alpha subunit family [H]

Homologues:

Organism=Homo sapiens, GI109452591, Length=284, Percent_Identity=67.6056338028169, Blast_Score=330, Evalue=9e-91,
Organism=Homo sapiens, GI38569423, Length=259, Percent_Identity=33.2046332046332, Blast_Score=106, Evalue=3e-23,
Organism=Homo sapiens, GI38569421, Length=259, Percent_Identity=33.2046332046332, Blast_Score=105, Evalue=3e-23,
Organism=Escherichia coli, GI1786949, Length=285, Percent_Identity=87.0175438596491, Blast_Score=500, Evalue=1e-143,
Organism=Caenorhabditis elegans, GI17550194, Length=288, Percent_Identity=63.8888888888889, Blast_Score=348, Evalue=2e-96,
Organism=Caenorhabditis elegans, GI17553126, Length=289, Percent_Identity=62.6297577854671, Blast_Score=335, Evalue=1e-92,
Organism=Caenorhabditis elegans, GI17557344, Length=255, Percent_Identity=30.9803921568627, Blast_Score=104, Evalue=6e-23,
Organism=Caenorhabditis elegans, GI17551266, Length=255, Percent_Identity=30.9803921568627, Blast_Score=102, Evalue=2e-22,
Organism=Saccharomyces cerevisiae, GI6324716, Length=292, Percent_Identity=53.0821917808219, Blast_Score=283, Evalue=2e-77,
Organism=Drosophila melanogaster, GI28574296, Length=288, Percent_Identity=62.8472222222222, Blast_Score=333, Evalue=9e-92,
Organism=Drosophila melanogaster, GI21356559, Length=288, Percent_Identity=58.3333333333333, Blast_Score=327, Evalue=4e-90,
Organism=Drosophila melanogaster, GI281363477, Length=259, Percent_Identity=28.957528957529, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI281363475, Length=259, Percent_Identity=28.957528957529, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI281363473, Length=259, Percent_Identity=28.957528957529, Blast_Score=100, Evalue=2e-21,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017440
- InterPro:   IPR003781
- InterPro:   IPR005810
- InterPro:   IPR005811
- InterPro:   IPR016040
- InterPro:   IPR016102 [H]

Pfam domain/function: PF02629 CoA_binding; PF00549 Ligase_CoA [H]

EC number: =6.2.1.5 [H]

Molecular weight: Translated: 29700; Mature: 29568

Theoretical pI: Translated: 5.35; Mature: 5.35

Prosite motif: PS01216 SUCCINYL_COA_LIG_1 ; PS00399 SUCCINYL_COA_LIG_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVLINKDTKVICQGFTGGQGTFHSQQAIDYGTQMVGGVSPGKGGTEHLGLPVFNTVKDA
CEEEEECCCEEEEECCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHH
VAATGATASVIYVPAPFCKDAILEAIDGGIELIVCITEGIPTLDMLEVKVKLEETGVRMI
HHHCCCCEEEEEECCCHHHHHHHHHHCCCEEEEEEEECCCCCEEEEEEEEEEECCCEEEE
GPNCPGVITPGECKIGIMPGHIHLKGKVGIVSRSGTLTYEAVKQTTDEGFGQSTCVGIGG
CCCCCCEECCCCEEEEEECCEEEEEEEEEEEECCCCEEHHHHHHHHHCCCCCCEEEECCC
DPIPGTNFIDVLEMFQNDPQTEAIVMIGEIGGTAEEEAAAYIKANVTKPVVSYIAGVTAP
CCCCCCHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHEEEEECCHHHHHHHHHCCCCC
AGKRMGHAGAIIAGGKGTAADKFAALEAAGVTTVRSLADIGKALRAKTGW
CCCCCCCCCEEEECCCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SVLINKDTKVICQGFTGGQGTFHSQQAIDYGTQMVGGVSPGKGGTEHLGLPVFNTVKDA
EEEEECCCEEEEECCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHH
VAATGATASVIYVPAPFCKDAILEAIDGGIELIVCITEGIPTLDMLEVKVKLEETGVRMI
HHHCCCCEEEEEECCCHHHHHHHHHHCCCEEEEEEEECCCCCEEEEEEEEEEECCCEEEE
GPNCPGVITPGECKIGIMPGHIHLKGKVGIVSRSGTLTYEAVKQTTDEGFGQSTCVGIGG
CCCCCCEECCCCEEEEEECCEEEEEEEEEEEECCCCEEHHHHHHHHHCCCCCCEEEECCC
DPIPGTNFIDVLEMFQNDPQTEAIVMIGEIGGTAEEEAAAYIKANVTKPVVSYIAGVTAP
CCCCCCHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHEEEEECCHHHHHHHHHCCCCC
AGKRMGHAGAIIAGGKGTAADKFAALEAAGVTTVRSLADIGKALRAKTGW
CCCCCCCCCEEEECCCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043; 8581173 [H]