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The map label for this gene is sucC [H]

Identifier: 117920159

GI number: 117920159

Start: 2016832

End: 2017998

Strand: Direct

Name: sucC [H]

Synonym: Shewana3_1712

Alternate gene names: 117920159

Gene position: 2016832-2017998 (Clockwise)

Preceding gene: 117920158

Following gene: 117920160

Centisome position: 40.56

GC content: 46.96

Gene sequence:

>1167_bases
ATGAATTTGCATGAGTATCAGGCAAAATCCCTATTTGCCGAATATGGTTTACCAGTGTCAGAAGGTTTTGCATGTGATAC
AGCCCAAGAAGCTGTAGAAGCGGCAGGCCGTATTGGCGGAAATTTATGGGTTGTTAAGTGTCAAGTACACGCAGGCGGCC
GCGGTAAAGCGGGTGGCGTTAAAGTCACTGGCGATAAAGAAGAAATCAGAGCCTTTGCCGAACACTGGTTAGGCAAAAAT
CTGGTGACTTATCAAACTGATGAGAAAGGTCAGCCGGTTGCTAAAATTTTAGTAGAAAGCTGCACTGACATCGCTAACGA
ACTGTACTTAGGTGCAGTAGTTGACCGCGCTACCCGTCGCGTAGTGTTTATGGCGTCAACTGAAGGTGGTGTTGAGATTG
AGAAAGTGGCCGAAGAAACGCCAGAACTCATTCACAAAGCGATCATCGATCCACTGACTGGTCCTCAACCATACCAAGCA
CGTGATCTTGGCTTCAAACTGGGCTTAAACCCAACTCAAATGAAGCAATTCACCAAGATCTTCATGGGTCTGGCGACTAT
GTTCGTTGATCACGATTTCGCTCTGCTGGAAATCAACCCACTGGTTATCACCACTGAAGGTAACCTGCACTGCTTAGACG
GTAAAATTGGTATCGATGGTAACGCACTGTTCCGTCAAGCAAAAATCAAAGCAATGCACGATCCATCTCAAGATGACGCC
CGTGAAGCTCACGCTGCAATGTTCGAACTGAACTATGTTGCGCTAGACGGAAACGTAGGTTGTATGGTGAACGGTGCTGG
CCTAGCGATGGGTACTATGGACATCGTTAACCTGCACGGCGGCAAGCCAGCTAACTTCCTCGACGTAGGTGGTGGCGCGA
CTAAAGAACGTGTTGCTGAAGCATTCAAGATCATTCTGTCTGACAGCAATGTGAAAGCCGTTCTAGTTAACATCTTCGGT
GGTATCGTACGTTGTGACATGATCGCAGAAGGTATCATTGGCGCTGTTAAAGAAGTTGGCGTTAAAGTTCCAGTTGTAGT
GCGTTTAGAAGGTACTAACGCTGAATTAGGCCGTGAAGTATTAGCTAAATCAGGTCTTGATATCATTGCAGCTAACAGTC
TGACTGATGCGGCTGAGCAAGTAGTTAAAGCTGCGGAGGGCAAATAA

Upstream 100 bases:

>100_bases
AAAGTTTAGCCTGTTAGTTAAAGACAAGCGTCAGACATACCCTCGTGACTGGCCCCGTGGGGCCAGTTGGATTTGATTAG
AAGTATACGGATAGATCATC

Downstream 100 bases:

>100_bases
TGTCTGTATTAATTAACAAAGATACCAAGGTAATCTGCCAAGGCTTTACCGGTGGTCAAGGTACTTTCCACTCTCAACAA
GCTATCGATTACGGTACGCA

Product: succinyl-CoA synthetase subunit beta

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit beta; SCS-beta [H]

Number of amino acids: Translated: 388; Mature: 388

Protein sequence:

>388_residues
MNLHEYQAKSLFAEYGLPVSEGFACDTAQEAVEAAGRIGGNLWVVKCQVHAGGRGKAGGVKVTGDKEEIRAFAEHWLGKN
LVTYQTDEKGQPVAKILVESCTDIANELYLGAVVDRATRRVVFMASTEGGVEIEKVAEETPELIHKAIIDPLTGPQPYQA
RDLGFKLGLNPTQMKQFTKIFMGLATMFVDHDFALLEINPLVITTEGNLHCLDGKIGIDGNALFRQAKIKAMHDPSQDDA
REAHAAMFELNYVALDGNVGCMVNGAGLAMGTMDIVNLHGGKPANFLDVGGGATKERVAEAFKIILSDSNVKAVLVNIFG
GIVRCDMIAEGIIGAVKEVGVKVPVVVRLEGTNAELGREVLAKSGLDIIAANSLTDAAEQVVKAAEGK

Sequences:

>Translated_388_residues
MNLHEYQAKSLFAEYGLPVSEGFACDTAQEAVEAAGRIGGNLWVVKCQVHAGGRGKAGGVKVTGDKEEIRAFAEHWLGKN
LVTYQTDEKGQPVAKILVESCTDIANELYLGAVVDRATRRVVFMASTEGGVEIEKVAEETPELIHKAIIDPLTGPQPYQA
RDLGFKLGLNPTQMKQFTKIFMGLATMFVDHDFALLEINPLVITTEGNLHCLDGKIGIDGNALFRQAKIKAMHDPSQDDA
REAHAAMFELNYVALDGNVGCMVNGAGLAMGTMDIVNLHGGKPANFLDVGGGATKERVAEAFKIILSDSNVKAVLVNIFG
GIVRCDMIAEGIIGAVKEVGVKVPVVVRLEGTNAELGREVLAKSGLDIIAANSLTDAAEQVVKAAEGK
>Mature_388_residues
MNLHEYQAKSLFAEYGLPVSEGFACDTAQEAVEAAGRIGGNLWVVKCQVHAGGRGKAGGVKVTGDKEEIRAFAEHWLGKN
LVTYQTDEKGQPVAKILVESCTDIANELYLGAVVDRATRRVVFMASTEGGVEIEKVAEETPELIHKAIIDPLTGPQPYQA
RDLGFKLGLNPTQMKQFTKIFMGLATMFVDHDFALLEINPLVITTEGNLHCLDGKIGIDGNALFRQAKIKAMHDPSQDDA
REAHAAMFELNYVALDGNVGCMVNGAGLAMGTMDIVNLHGGKPANFLDVGGGATKERVAEAFKIILSDSNVKAVLVNIFG
GIVRCDMIAEGIIGAVKEVGVKVPVVVRLEGTNAELGREVLAKSGLDIIAANSLTDAAEQVVKAAEGK

Specific function: Tricarboxylic acid cycle. [C]

COG id: COG0045

COG function: function code C; Succinyl-CoA synthetase, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-grasp domain [H]

Homologues:

Organism=Homo sapiens, GI11321583, Length=393, Percent_Identity=45.5470737913486, Blast_Score=339, Evalue=3e-93,
Organism=Homo sapiens, GI157779135, Length=387, Percent_Identity=45.4780361757106, Blast_Score=320, Evalue=2e-87,
Organism=Homo sapiens, GI294862256, Length=366, Percent_Identity=45.9016393442623, Blast_Score=305, Evalue=7e-83,
Organism=Escherichia coli, GI1786948, Length=388, Percent_Identity=77.0618556701031, Blast_Score=590, Evalue=1e-170,
Organism=Caenorhabditis elegans, GI17567829, Length=389, Percent_Identity=44.7300771208226, Blast_Score=318, Evalue=2e-87,
Organism=Caenorhabditis elegans, GI17539378, Length=400, Percent_Identity=42.25, Blast_Score=308, Evalue=4e-84,
Organism=Saccharomyces cerevisiae, GI6321683, Length=393, Percent_Identity=43.0025445292621, Blast_Score=330, Evalue=2e-91,
Organism=Drosophila melanogaster, GI21356231, Length=397, Percent_Identity=43.0730478589421, Blast_Score=299, Evalue=2e-81,
Organism=Drosophila melanogaster, GI161078106, Length=393, Percent_Identity=43.0025445292621, Blast_Score=297, Evalue=1e-80,
Organism=Drosophila melanogaster, GI24645208, Length=393, Percent_Identity=43.0025445292621, Blast_Score=297, Evalue=1e-80,
Organism=Drosophila melanogaster, GI281361397, Length=394, Percent_Identity=43.1472081218274, Blast_Score=295, Evalue=4e-80,
Organism=Drosophila melanogaster, GI281361395, Length=394, Percent_Identity=43.1472081218274, Blast_Score=295, Evalue=4e-80,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2361 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011761
- InterPro:   IPR013650
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR005811
- InterPro:   IPR017866
- InterPro:   IPR005809
- InterPro:   IPR016102 [H]

Pfam domain/function: PF08442 ATP-grasp_2; PF00549 Ligase_CoA [H]

EC number: =6.2.1.5 [H]

Molecular weight: Translated: 41341; Mature: 41341

Theoretical pI: Translated: 5.06; Mature: 5.06

Prosite motif: PS50975 ATP_GRASP ; PS01217 SUCCINYL_COA_LIG_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLHEYQAKSLFAEYGLPVSEGFACDTAQEAVEAAGRIGGNLWVVKCQVHAGGRGKAGGV
CCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEEEEECCCCCCCCCE
KVTGDKEEIRAFAEHWLGKNLVTYQTDEKGQPVAKILVESCTDIANELYLGAVVDRATRR
EEECCHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCE
VVFMASTEGGVEIEKVAEETPELIHKAIIDPLTGPQPYQARDLGFKLGLNPTQMKQFTKI
EEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHCCCEEECCCHHHHHHHHHH
FMGLATMFVDHDFALLEINPLVITTEGNLHCLDGKIGIDGNALFRQAKIKAMHDPSQDDA
HHHHHHHHHCCCEEEEEEEEEEEEECCCEEEECCEECCCCHHHHHHHHHHHCCCCCCHHH
REAHAAMFELNYVALDGNVGCMVNGAGLAMGTMDIVNLHGGKPANFLDVGGGATKERVAE
HHHHHHEEEEEEEEECCCCEEEEECCCEEECCEEEEEECCCCCCCEEECCCCCCHHHHHH
AFKIILSDSNVKAVLVNIFGGIVRCDMIAEGIIGAVKEVGVKVPVVVRLEGTNAELGREV
HHHHHCCCCCCCEEHEEHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCHHHHHHH
LAKSGLDIIAANSLTDAAEQVVKAAEGK
HHHCCCCEEEECCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNLHEYQAKSLFAEYGLPVSEGFACDTAQEAVEAAGRIGGNLWVVKCQVHAGGRGKAGGV
CCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEEEEECCCCCCCCCE
KVTGDKEEIRAFAEHWLGKNLVTYQTDEKGQPVAKILVESCTDIANELYLGAVVDRATRR
EEECCHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCE
VVFMASTEGGVEIEKVAEETPELIHKAIIDPLTGPQPYQARDLGFKLGLNPTQMKQFTKI
EEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHCCCEEECCCHHHHHHHHHH
FMGLATMFVDHDFALLEINPLVITTEGNLHCLDGKIGIDGNALFRQAKIKAMHDPSQDDA
HHHHHHHHHCCCEEEEEEEEEEEEECCCEEEECCEECCCCHHHHHHHHHHHCCCCCCHHH
REAHAAMFELNYVALDGNVGCMVNGAGLAMGTMDIVNLHGGKPANFLDVGGGATKERVAE
HHHHHHEEEEEEEEECCCCEEEEECCCEEECCEEEEEECCCCCCCEEECCCCCCHHHHHH
AFKIILSDSNVKAVLVNIFGGIVRCDMIAEGIIGAVKEVGVKVPVVVRLEGTNAELGREV
HHHHHCCCCCCCEEHEEHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCHHHHHHH
LAKSGLDIIAANSLTDAAEQVVKAAEGK
HHHCCCCEEEECCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA