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The map label for this gene is mdtA [H]

Identifier: 117920105

GI number: 117920105

Start: 1948635

End: 1949717

Strand: Direct

Name: mdtA [H]

Synonym: Shewana3_1658

Alternate gene names: 117920105

Gene position: 1948635-1949717 (Clockwise)

Preceding gene: 117920104

Following gene: 117920106

Centisome position: 39.19

GC content: 50.42

Gene sequence:

>1083_bases
ATGAAAAAAATCATAATTATCATCGCCATTTTGGCTGCGGGCTGGTTTGGATACCAAAGTATGCAACCCCAAGCACCTCA
GCAAGCAAAAGTTAAGCTCACCCCTAATGTGGTCATCGCGATGGCCGCCATGGCCCCAGTGCGTGACGAAGTCGAAGCCA
TAGGCACCAACAAGGCCTTTGAGTCAGTCACTATCACGCCTAAGGTCACCGATGTAGTCACCTCACTCAAGTTTGATGAT
GGAGATATCGTCAAGAAGGGCGACTTATTGGTGCAGTTGCAAAATGCCGAGCAGATAGCCAAAGTGAAAGTGGCGCAGGT
GAAGGTGAGCGACAACCAGCGCGAATTAGCGCGGATCAGCTCTTTGGTTACTAGCCGCACTGTGGCGGAGCTAGAGCGTG
ACCGCCTGCAAACCTTAATCGATACCACCCGCGCCGAGTTAGAGCAGGCACAATCATCCCTCAATGATCGCAGCATAGTG
GCGCCTTTTAATGGCCGTTTGGGTCTGCGCCAAGTGAGTGTGGGTAGCCTAGTGACTCCGGGGACTGAGATCACCACACT
CGATGATATTTCTAAGATTAAATTAGACTTTTCGGTGCCTGAGCGCTTTATTCAAGACCTACAGCCCGGCAAGCAAGTCG
AAGCCAAAGCCGTGGCGTTCCCCGATGAAATCTTTAAAGGCAAAGTGATTTCTATCGATAGCCGTGTAAACCCAACCACT
CGCGCCGTGATTGTACGAGCCGAAATCCCAAATCCTGATTTACGTTTACTGCCCGGCATGCTGATGAAGGTGAAACTCAT
CAAGCGCAGCCGCGAAGCTTTGATGCTGCCTGAGTCGGCGATTATCCCGATCCAAAAAGAGCACTTTGTTTACAGCGTCA
ATAAGGACAATGTGATTGAGCGTAAGCAAGTCACCATTGGTATTCGTACCCGCGGTTGGGTCGAAATCCTCGGTGGTTTA
GAGATTGGTGAAAATGTGGTGATCCGCGGGCTACTCAAAGTGCACCCAGGCGATGTGGTCAAAACCGAATTGGCCGAGAA
GTTTAGCTATCTTTCCGATGCTAATACGGAGCCAAGTGTATGA

Upstream 100 bases:

>100_bases
GTTGGCGTAATTTGTAAGAAAAAGTAAAACGTATTGATGCAATGATGCGAGTGGGTAAACTAGCCGTCACTAATGCGAGT
CATCATCATTTGGAAGCCAG

Downstream 100 bases:

>100_bases
TCCTGACAGATCTTTCCGTTAAACGACCGGTATTTGCCTCGGTTATTAGCCTATTGCTGGTGGCCTTTGGTTTAGTGGCA
TTCGATAAGTTACCGCTGCG

Product: RND family efflux transporter MFP subunit

Products: NA

Alternate protein names: Multidrug transporter mdtA [H]

Number of amino acids: Translated: 360; Mature: 360

Protein sequence:

>360_residues
MKKIIIIIAILAAGWFGYQSMQPQAPQQAKVKLTPNVVIAMAAMAPVRDEVEAIGTNKAFESVTITPKVTDVVTSLKFDD
GDIVKKGDLLVQLQNAEQIAKVKVAQVKVSDNQRELARISSLVTSRTVAELERDRLQTLIDTTRAELEQAQSSLNDRSIV
APFNGRLGLRQVSVGSLVTPGTEITTLDDISKIKLDFSVPERFIQDLQPGKQVEAKAVAFPDEIFKGKVISIDSRVNPTT
RAVIVRAEIPNPDLRLLPGMLMKVKLIKRSREALMLPESAIIPIQKEHFVYSVNKDNVIERKQVTIGIRTRGWVEILGGL
EIGENVVIRGLLKVHPGDVVKTELAEKFSYLSDANTEPSV

Sequences:

>Translated_360_residues
MKKIIIIIAILAAGWFGYQSMQPQAPQQAKVKLTPNVVIAMAAMAPVRDEVEAIGTNKAFESVTITPKVTDVVTSLKFDD
GDIVKKGDLLVQLQNAEQIAKVKVAQVKVSDNQRELARISSLVTSRTVAELERDRLQTLIDTTRAELEQAQSSLNDRSIV
APFNGRLGLRQVSVGSLVTPGTEITTLDDISKIKLDFSVPERFIQDLQPGKQVEAKAVAFPDEIFKGKVISIDSRVNPTT
RAVIVRAEIPNPDLRLLPGMLMKVKLIKRSREALMLPESAIIPIQKEHFVYSVNKDNVIERKQVTIGIRTRGWVEILGGL
EIGENVVIRGLLKVHPGDVVKTELAEKFSYLSDANTEPSV
>Mature_360_residues
MKKIIIIIAILAAGWFGYQSMQPQAPQQAKVKLTPNVVIAMAAMAPVRDEVEAIGTNKAFESVTITPKVTDVVTSLKFDD
GDIVKKGDLLVQLQNAEQIAKVKVAQVKVSDNQRELARISSLVTSRTVAELERDRLQTLIDTTRAELEQAQSSLNDRSIV
APFNGRLGLRQVSVGSLVTPGTEITTLDDISKIKLDFSVPERFIQDLQPGKQVEAKAVAFPDEIFKGKVISIDSRVNPTT
RAVIVRAEIPNPDLRLLPGMLMKVKLIKRSREALMLPESAIIPIQKEHFVYSVNKDNVIERKQVTIGIRTRGWVEILGGL
EIGENVVIRGLLKVHPGDVVKTELAEKFSYLSDANTEPSV

Specific function: Unknown

COG id: COG0845

COG function: function code M; Membrane-fusion protein

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI87082036, Length=323, Percent_Identity=29.7213622291022, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1789665, Length=380, Percent_Identity=25.2631578947368, Blast_Score=88, Evalue=9e-19,
Organism=Escherichia coli, GI1789929, Length=339, Percent_Identity=27.1386430678466, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI1786668, Length=377, Percent_Identity=24.9336870026525, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI87081796, Length=320, Percent_Identity=26.25, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022824
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 39672; Mature: 39672

Theoretical pI: Translated: 9.73; Mature: 9.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKIIIIIAILAAGWFGYQSMQPQAPQQAKVKLTPNVVIAMAAMAPVRDEVEAIGTNKAF
CCEEEEEHHHHHHHHCCCCCCCCCCCCCCEEEECCCCEEEHHHHCCHHHHHHHHCCCCCC
ESVTITPKVTDVVTSLKFDDGDIVKKGDLLVQLQNAEQIAKVKVAQVKVSDNQRELARIS
CEEEECCHHHHHHHHEECCCCCEEECCCEEEEECCHHHHHHEEEEEEEECCCHHHHHHHH
SLVTSRTVAELERDRLQTLIDTTRAELEQAQSSLNDRSIVAPFNGRLGLRQVSVGSLVTP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCEEEECCCCEECC
GTEITTLDDISKIKLDFSVPERFIQDLQPGKQVEAKAVAFPDEIFKGKVISIDSRVNPTT
CCCEEECCCCEEEEEECCCHHHHHHHCCCCCCCCCEEEECCHHHHCCCEEEECCCCCCCE
RAVIVRAEIPNPDLRLLPGMLMKVKLIKRSREALMLPESAIIPIQKEHFVYSVNKDNVIE
EEEEEEEECCCCCHHHHHHHHHHHHHHHHCHHHEECCCCCCCCEECCCEEEECCCCCCEE
RKQVTIGIRTRGWVEILGGLEIGENVVIRGLLKVHPGDVVKTELAEKFSYLSDANTEPSV
EEEEEEEEECCCHHHHHCCCCCCCHHEEEEHEECCCCCHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MKKIIIIIAILAAGWFGYQSMQPQAPQQAKVKLTPNVVIAMAAMAPVRDEVEAIGTNKAF
CCEEEEEHHHHHHHHCCCCCCCCCCCCCCEEEECCCCEEEHHHHCCHHHHHHHHCCCCCC
ESVTITPKVTDVVTSLKFDDGDIVKKGDLLVQLQNAEQIAKVKVAQVKVSDNQRELARIS
CEEEECCHHHHHHHHEECCCCCEEECCCEEEEECCHHHHHHEEEEEEEECCCHHHHHHHH
SLVTSRTVAELERDRLQTLIDTTRAELEQAQSSLNDRSIVAPFNGRLGLRQVSVGSLVTP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCEEEECCCCEECC
GTEITTLDDISKIKLDFSVPERFIQDLQPGKQVEAKAVAFPDEIFKGKVISIDSRVNPTT
CCCEEECCCCEEEEEECCCHHHHHHHCCCCCCCCCEEEECCHHHHCCCEEEECCCCCCCE
RAVIVRAEIPNPDLRLLPGMLMKVKLIKRSREALMLPESAIIPIQKEHFVYSVNKDNVIE
EEEEEEEECCCCCHHHHHHHHHHHHHHHHCHHHEECCCCCCCCEECCCEEEECCCCCCEE
RKQVTIGIRTRGWVEILGGLEIGENVVIRGLLKVHPGDVVKTELAEKFSYLSDANTEPSV
EEEEEEEEECCCHHHHHCCCCCCCHHEEEEHEECCCCCHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA