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The map label for this gene is trpB [H]

Identifier: 117919964

GI number: 117919964

Start: 1765871

End: 1767061

Strand: Reverse

Name: trpB [H]

Synonym: Shewana3_1516

Alternate gene names: 117919964

Gene position: 1767061-1765871 (Counterclockwise)

Preceding gene: 117919965

Following gene: 117919963

Centisome position: 35.54

GC content: 52.31

Gene sequence:

>1191_bases
ATGTCACAGTTAAAGCTTAACCCTTATTTCGGCGAATACGGCGGTATGTATGTGCCGCAGATTTTAGTCCCCGCCCTCAA
GCAACTCGAAAACGCCTTTGTCGAAGCGCAGGCCGATGAATCCTTTCAAGCCGAGTTTACCGATCTACTGAAAAACTACG
CGGGCCGCCCAACGGCACTGACCTTAACCCGCAATTTAAGCCCTAACCCTATGGTGAAAATCTACCTCAAGCGGGAAGAT
TTACTCCACGGCGGCGCCCATAAAACCAACCAGGTATTGGGCCAAGCATTATTGGCTAAACGTATGGGTAAAAAGGAGAT
TATTGCAGAAACCGGCGCAGGCCAACACGGTGTTGCCACCGCCCTTGCCTGTGCGCTACTGGGATTAAAGTGCAAAGTGT
ATATGGGCGCGAAAGACGTTGCCCGCCAATCACCTAACGTATTTAGAATGCGTTTGATGGGCGCAGAAGTCATTCCTGTC
ACCTCAGGCTCTGCCACCTTAAAAGATGCCTGTAACGAGGCGATGCGCGACTGGTCCGGCAGCTACGAAAAAGCCCACTA
TCTATTAGGCACAGCTGCAGGGCCGCACCCTTTCCCGACTATAGTGCGTGAGTTCCAACGTATGATAGGCGAAGAAACCA
AGAAGCAAATGCTGGAGCGCGAAGGTCGTCTGCCCGATGCGGTGATCGCCTGTGTCGGCGGAGGCTCCAATGCTATCGGT
ATGTTTGCCGACTTTATTGATGAAACCAGTGTCGAGCTGATTGGGGTCGAACCCGCAGGTAAAGGCATCGATACCCATAT
GCACGGTGCGCCACTCAAACATGGCAAAACTGGGATTTTCTTTGGTATGAAGGCGCCCTTGATGCAGGACAGCGAAGGCC
AAATCGAAGAATCCTATTCGATTTCGGCAGGCCTTGACTTCCCCTCCGTTGGCCCACAACACGCCCATTTGAACGCGATT
GGCCGTGCGCGCTACGAATCGGCCACCGATGATGAAGCCCTAGAAGCCTTCCAATTATTGGCTCGCAGCGAAGGGATTAT
CCCTGCGCTCGAATCGGCCCACGCCCTCGCTTACGCCCTGCGCCTAGCGAAAGAGTGCACTAAAGAAACCATTTTGGTCG
TTAACCTCTCGGGACGAGGCGATAAGGATATTTTCACTGTGTCAGACATTTTAAACGGTAAAGAGGAATAA

Upstream 100 bases:

>100_bases
TTATAAAAACCTGTGCAAAGCACAGGCTAGCCAGAATTGAAACTCGATGGCGTTAACCTAAACCGCCATCGAAACAAATG
AATAGGATAAGGAACAAGGT

Downstream 100 bases:

>100_bases
CAACGATGAGCAACACTGCAACCCAAACTATCCCTCAGCAAGGCGGCCGTTATCACGCAGCGTTTAGCCGTTTAAAAGCC
GAAGGCCGCGGCGCCTTTGT

Product: tryptophan synthase subunit beta

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 396; Mature: 395

Protein sequence:

>396_residues
MSQLKLNPYFGEYGGMYVPQILVPALKQLENAFVEAQADESFQAEFTDLLKNYAGRPTALTLTRNLSPNPMVKIYLKRED
LLHGGAHKTNQVLGQALLAKRMGKKEIIAETGAGQHGVATALACALLGLKCKVYMGAKDVARQSPNVFRMRLMGAEVIPV
TSGSATLKDACNEAMRDWSGSYEKAHYLLGTAAGPHPFPTIVREFQRMIGEETKKQMLEREGRLPDAVIACVGGGSNAIG
MFADFIDETSVELIGVEPAGKGIDTHMHGAPLKHGKTGIFFGMKAPLMQDSEGQIEESYSISAGLDFPSVGPQHAHLNAI
GRARYESATDDEALEAFQLLARSEGIIPALESAHALAYALRLAKECTKETILVVNLSGRGDKDIFTVSDILNGKEE

Sequences:

>Translated_396_residues
MSQLKLNPYFGEYGGMYVPQILVPALKQLENAFVEAQADESFQAEFTDLLKNYAGRPTALTLTRNLSPNPMVKIYLKRED
LLHGGAHKTNQVLGQALLAKRMGKKEIIAETGAGQHGVATALACALLGLKCKVYMGAKDVARQSPNVFRMRLMGAEVIPV
TSGSATLKDACNEAMRDWSGSYEKAHYLLGTAAGPHPFPTIVREFQRMIGEETKKQMLEREGRLPDAVIACVGGGSNAIG
MFADFIDETSVELIGVEPAGKGIDTHMHGAPLKHGKTGIFFGMKAPLMQDSEGQIEESYSISAGLDFPSVGPQHAHLNAI
GRARYESATDDEALEAFQLLARSEGIIPALESAHALAYALRLAKECTKETILVVNLSGRGDKDIFTVSDILNGKEE
>Mature_395_residues
SQLKLNPYFGEYGGMYVPQILVPALKQLENAFVEAQADESFQAEFTDLLKNYAGRPTALTLTRNLSPNPMVKIYLKREDL
LHGGAHKTNQVLGQALLAKRMGKKEIIAETGAGQHGVATALACALLGLKCKVYMGAKDVARQSPNVFRMRLMGAEVIPVT
SGSATLKDACNEAMRDWSGSYEKAHYLLGTAAGPHPFPTIVREFQRMIGEETKKQMLEREGRLPDAVIACVGGGSNAIGM
FADFIDETSVELIGVEPAGKGIDTHMHGAPLKHGKTGIFFGMKAPLMQDSEGQIEESYSISAGLDFPSVGPQHAHLNAIG
RARYESATDDEALEAFQLLARSEGIIPALESAHALAYALRLAKECTKETILVVNLSGRGDKDIFTVSDILNGKEE

Specific function: The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine [H]

COG id: COG0133

COG function: function code E; Tryptophan synthase beta chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trpB family [H]

Homologues:

Organism=Escherichia coli, GI1787515, Length=392, Percent_Identity=80.3571428571429, Blast_Score=651, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6321412, Length=384, Percent_Identity=53.6458333333333, Blast_Score=424, Evalue=1e-120,

Paralogues:

None

Copy number: 360 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 5,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001926
- InterPro:   IPR006653
- InterPro:   IPR006654
- InterPro:   IPR023026 [H]

Pfam domain/function: PF00291 PALP [H]

EC number: =4.2.1.20 [H]

Molecular weight: Translated: 42807; Mature: 42675

Theoretical pI: Translated: 6.30; Mature: 6.30

Prosite motif: PS00168 TRP_SYNTHASE_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQLKLNPYFGEYGGMYVPQILVPALKQLENAFVEAQADESFQAEFTDLLKNYAGRPTAL
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCEEE
TLTRNLSPNPMVKIYLKREDLLHGGAHKTNQVLGQALLAKRMGKKEIIAETGAGQHGVAT
EEECCCCCCCEEEEEEEHHHHHCCCCCHHHHHHHHHHHHHHCCCHHHHHHCCCCCCHHHH
ALACALLGLKCKVYMGAKDVARQSPNVFRMRLMGAEVIPVTSGSATLKDACNEAMRDWSG
HHHHHHHCCCEEEEECCHHHHHCCCCCEEEEECCCEEEEECCCCHHHHHHHHHHHHHCCC
SYEKAHYLLGTAAGPHPFPTIVREFQRMIGEETKKQMLEREGRLPDAVIACVGGGSNAIG
CHHHHHEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHH
MFADFIDETSVELIGVEPAGKGIDTHMHGAPLKHGKTGIFFGMKAPLMQDSEGQIEESYS
HHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCHHCCE
ISAGLDFPSVGPQHAHLNAIGRARYESATDDEALEAFQLLARSEGIIPALESAHALAYAL
EECCCCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
RLAKECTKETILVVNLSGRGDKDIFTVSDILNGKEE
HHHHHHCCCEEEEEEECCCCCCCEEEHHHHHCCCCC
>Mature Secondary Structure 
SQLKLNPYFGEYGGMYVPQILVPALKQLENAFVEAQADESFQAEFTDLLKNYAGRPTAL
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCEEE
TLTRNLSPNPMVKIYLKREDLLHGGAHKTNQVLGQALLAKRMGKKEIIAETGAGQHGVAT
EEECCCCCCCEEEEEEEHHHHHCCCCCHHHHHHHHHHHHHHCCCHHHHHHCCCCCCHHHH
ALACALLGLKCKVYMGAKDVARQSPNVFRMRLMGAEVIPVTSGSATLKDACNEAMRDWSG
HHHHHHHCCCEEEEECCHHHHHCCCCCEEEEECCCEEEEECCCCHHHHHHHHHHHHHCCC
SYEKAHYLLGTAAGPHPFPTIVREFQRMIGEETKKQMLEREGRLPDAVIACVGGGSNAIG
CHHHHHEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHH
MFADFIDETSVELIGVEPAGKGIDTHMHGAPLKHGKTGIFFGMKAPLMQDSEGQIEESYS
HHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCHHCCE
ISAGLDFPSVGPQHAHLNAIGRARYESATDDEALEAFQLLARSEGIIPALESAHALAYAL
EECCCCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
RLAKECTKETILVVNLSGRGDKDIFTVSDILNGKEE
HHHHHHCCCEEEEEEECCCCCCCEEEHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA