Click here to switch to the map view.

The map label for this gene is xapR [H]

Identifier: 117919719

GI number: 117919719

Start: 1485411

End: 1485686

Strand: Direct

Name: xapR [H]

Synonym: Shewana3_1271

Alternate gene names: 117919719

Gene position: 1485411-1485686 (Clockwise)

Preceding gene: 117919718

Following gene: 117919720

Centisome position: 29.87

GC content: 57.61

Gene sequence:

>276_bases
ATGGAATGTCGGCATCTGCGTTGCCTTCTGGCCGTGGCCGAAGAACTACACTTCGCTCGTGCTGCTGAACGACTGCATAT
TGAGCAGTCGCCGCTATCGCGTGCCATCAAAGAGCTGGAAGCAGACCTGGGTGAACAGCTGTTCGTCCATACCAGCCGCA
GCACGCGACTGACACGGGCCGGTAAATTGTTTTTGGAGCATGTGCCACGCGTTTCTGCGAGAACCCCGGCGTCTTTTGTC
CCACGGATCTGGCACGGGTCGAATGTGACAGCGTAG

Upstream 100 bases:

>100_bases
CGGGAATGCTCTACAACTTGGGTGCCGCGCTACTTATATGCTTTTTGTTGCTTATTCTGGCAAGGTCGCAAAGGTCGGCT
AGCTAGCAAAAGAGGAGTTA

Downstream 100 bases:

>100_bases
AAGTCGTTGCCCGGAACTGGAGGCGCATCAAGGAATTTGGCAACGAGTGGCGATCATGGCCTGCGAAAGGTCGCCCATGT
CCGTGCCGATCTTGGCGAGA

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: Xanthosine operon regulatory protein [H]

Number of amino acids: Translated: 91; Mature: 91

Protein sequence:

>91_residues
MECRHLRCLLAVAEELHFARAAERLHIEQSPLSRAIKELEADLGEQLFVHTSRSTRLTRAGKLFLEHVPRVSARTPASFV
PRIWHGSNVTA

Sequences:

>Translated_91_residues
MECRHLRCLLAVAEELHFARAAERLHIEQSPLSRAIKELEADLGEQLFVHTSRSTRLTRAGKLFLEHVPRVSARTPASFV
PRIWHGSNVTA
>Mature_91_residues
MECRHLRCLLAVAEELHFARAAERLHIEQSPLSRAIKELEADLGEQLFVHTSRSTRLTRAGKLFLEHVPRVSARTPASFV
PRIWHGSNVTA

Specific function: Positive regulator required for the expression of xapA and xapB. Binds to the inducer xanthosine [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI2367136, Length=65, Percent_Identity=60, Blast_Score=75, Evalue=8e-16,
Organism=Escherichia coli, GI1787879, Length=65, Percent_Identity=58.4615384615385, Blast_Score=74, Evalue=1e-15,
Organism=Escherichia coli, GI1788887, Length=67, Percent_Identity=49.2537313432836, Blast_Score=63, Evalue=3e-12,
Organism=Escherichia coli, GI1790208, Length=62, Percent_Identity=46.7741935483871, Blast_Score=60, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 10324; Mature: 10324

Theoretical pI: Translated: 9.74; Mature: 9.74

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MECRHLRCLLAVAEELHFARAAERLHIEQSPLSRAIKELEADLGEQLFVHTSRSTRLTRA
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCHHHEEECCCCCHHHHH
GKLFLEHVPRVSARTPASFVPRIWHGSNVTA
HHHHHHHCCCCCCCCCHHHCCHHCCCCCCCC
>Mature Secondary Structure
MECRHLRCLLAVAEELHFARAAERLHIEQSPLSRAIKELEADLGEQLFVHTSRSTRLTRA
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCHHHEEECCCCCHHHHH
GKLFLEHVPRVSARTPASFVPRIWHGSNVTA
HHHHHHHCCCCCCCCCHHHCCHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2201776; 9205837; 9278503; 7559336 [H]