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The map label for this gene is xseA

Identifier: 117919683

GI number: 117919683

Start: 1438638

End: 1439984

Strand: Reverse

Name: xseA

Synonym: Shewana3_1234

Alternate gene names: 117919683

Gene position: 1439984-1438638 (Counterclockwise)

Preceding gene: 117919688

Following gene: 117919674

Centisome position: 28.96

GC content: 50.26

Gene sequence:

>1347_bases
ATGCAAGTCCCTAAAAATAATATTTATACCGTCTCACGCCTTAATGGTGAAGTCAGGCAAATTCTCGAGGGACAACTGGG
AAAAGTCTGGTTAAATGGTGAAATTTCCAACTTTTCGGCCCCCAGTTCAGGACATTGGTATTTAACCCTTAAGGATCATT
ATTCCCAAATTCGCTGCGCCATGTTCAAGGGGCGCAACCAAAGCGTGAGCTTTAAACCTGTGAATGGTCAGCAGGTGCTC
GTGAAAGGCGCCATCAGCGTGTACGAGCCTAGAGGCGACTATCAATTATTGATTGAATCTATGCTCCCCGCAGGGGATGG
CTTACTGGCACAGCAATTTGAAGCGCTCAAAATGAAGCTCGCAGCGCAGGGATTATTTGCCGCCGACACTAAACGTCAGT
TACCGAAAAATATTCAACGTATTGGGGTCATCACCTCCCCTACTGGCGCGGCTATCCGTGATGTGTTGCATGTGCTTGCC
CGCCGTGACCCTTCCATCGAAGTGATTATTTATCCGACACAAGTACAGGGTGAAAATGCGGATATGAATATCTGCCAAGC
CATCAATATCGCCAACCAACGGCTCGAGGTCGATGTATTACTGCTCACCCGCGGCGGCGGCTCACTCGAAGATTTATGGT
GTTTTAATAGCGAAGCGCTCGCCCATACCATCTACAACAGCGCTTTACCCGTTGTCAGCGCCGTAGGCCATGAAGTCGAC
ACTACCATTAGTGACTATGTGGCCGACGTTCGCGCCCCGACGCCTTCTGCGGGCGCAGAGCTACTGTCTCAGGATAGCGA
CAATAAGAGCCAACGCTTAGCCACTGTACTCTCGCGCCTCAAACAGAGCGCGAGCCACTATCAGCTCAAGCAGGAAAAAC
GCTTAAGTTTGCTCGAACACAGACTGCAACGCTTGGATCCTAAGCGCACCTTGCAACAATTTGAGCAGCGTTTCGATGAG
ATGCAATTACGGCTCGAAGCCGCATTGTCTAACAAACTGCACGGTTTAAGTCGCCGTCAGCAGCAACTGGCAAATCGCCT
CGAGCAGCAATCTCCAAAGCACAAGCTCGCACTCGAGACCAATAGGTTGAGCTATTTAGCGACGCGTTTGCAGGATGCTA
TGCAAGATACCCTCAACCAAAGCGAGCAGCGGATCACATATGCCGCCCATCAATTGGAAACGGTTAGTCCATTAGCTACT
TTGAGCCGGGGTTACAGCATCACCACAGATGCAAATAACCAAGTCATAGACAATGCCGCCCAGCTGAGTGTGGGCGATAA
GATAAACACTCGCCTACGCCATGGACAAGTGCAGTCGACTGTGACGCAAATAACCGATGAAAGCTAA

Upstream 100 bases:

>100_bases
TAGGATTTTAGAGGTGAAATATTGCGGCGGGATTATACCTTGCATCTGGGGAGCGGTAAATGGAAAATAGTGAAAAAATC
CCATTTGCACGAGAAAACAC

Downstream 100 bases:

>100_bases
AACTAAATGGCCTTAAGGCTCAACGTCTAAGCCCATAACCATAAAGCATTTTATCTAAACAAGACTTATGATTGCGCCCT
AAAATACGCCAATAAAAAAG

Product: exodeoxyribonuclease VII large subunit

Products: NA

Alternate protein names: Exodeoxyribonuclease VII large subunit; Exonuclease VII large subunit

Number of amino acids: Translated: 448; Mature: 448

Protein sequence:

>448_residues
MQVPKNNIYTVSRLNGEVRQILEGQLGKVWLNGEISNFSAPSSGHWYLTLKDHYSQIRCAMFKGRNQSVSFKPVNGQQVL
VKGAISVYEPRGDYQLLIESMLPAGDGLLAQQFEALKMKLAAQGLFAADTKRQLPKNIQRIGVITSPTGAAIRDVLHVLA
RRDPSIEVIIYPTQVQGENADMNICQAINIANQRLEVDVLLLTRGGGSLEDLWCFNSEALAHTIYNSALPVVSAVGHEVD
TTISDYVADVRAPTPSAGAELLSQDSDNKSQRLATVLSRLKQSASHYQLKQEKRLSLLEHRLQRLDPKRTLQQFEQRFDE
MQLRLEAALSNKLHGLSRRQQQLANRLEQQSPKHKLALETNRLSYLATRLQDAMQDTLNQSEQRITYAAHQLETVSPLAT
LSRGYSITTDANNQVIDNAAQLSVGDKINTRLRHGQVQSTVTQITDES

Sequences:

>Translated_448_residues
MQVPKNNIYTVSRLNGEVRQILEGQLGKVWLNGEISNFSAPSSGHWYLTLKDHYSQIRCAMFKGRNQSVSFKPVNGQQVL
VKGAISVYEPRGDYQLLIESMLPAGDGLLAQQFEALKMKLAAQGLFAADTKRQLPKNIQRIGVITSPTGAAIRDVLHVLA
RRDPSIEVIIYPTQVQGENADMNICQAINIANQRLEVDVLLLTRGGGSLEDLWCFNSEALAHTIYNSALPVVSAVGHEVD
TTISDYVADVRAPTPSAGAELLSQDSDNKSQRLATVLSRLKQSASHYQLKQEKRLSLLEHRLQRLDPKRTLQQFEQRFDE
MQLRLEAALSNKLHGLSRRQQQLANRLEQQSPKHKLALETNRLSYLATRLQDAMQDTLNQSEQRITYAAHQLETVSPLAT
LSRGYSITTDANNQVIDNAAQLSVGDKINTRLRHGQVQSTVTQITDES
>Mature_448_residues
MQVPKNNIYTVSRLNGEVRQILEGQLGKVWLNGEISNFSAPSSGHWYLTLKDHYSQIRCAMFKGRNQSVSFKPVNGQQVL
VKGAISVYEPRGDYQLLIESMLPAGDGLLAQQFEALKMKLAAQGLFAADTKRQLPKNIQRIGVITSPTGAAIRDVLHVLA
RRDPSIEVIIYPTQVQGENADMNICQAINIANQRLEVDVLLLTRGGGSLEDLWCFNSEALAHTIYNSALPVVSAVGHEVD
TTISDYVADVRAPTPSAGAELLSQDSDNKSQRLATVLSRLKQSASHYQLKQEKRLSLLEHRLQRLDPKRTLQQFEQRFDE
MQLRLEAALSNKLHGLSRRQQQLANRLEQQSPKHKLALETNRLSYLATRLQDAMQDTLNQSEQRITYAAHQLETVSPLAT
LSRGYSITTDANNQVIDNAAQLSVGDKINTRLRHGQVQSTVTQITDES

Specific function: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides

COG id: COG1570

COG function: function code L; Exonuclease VII, large subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xseA family

Homologues:

Organism=Escherichia coli, GI1788856, Length=437, Percent_Identity=48.9702517162471, Blast_Score=432, Evalue=1e-122,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): EX7L_SHESA (A0KUK0)

Other databases:

- EMBL:   CP000469
- RefSeq:   YP_868875.1
- STRING:   A0KUK0
- GeneID:   4477154
- GenomeReviews:   CP000469_GR
- KEGG:   shn:Shewana3_1234
- NMPDR:   fig|94122.5.peg.1351
- eggNOG:   COG1570
- HOGENOM:   HBG634411
- OMA:   EQRASIG
- PhylomeDB:   A0KUK0
- ProtClustDB:   PRK00286
- BioCyc:   SSP94122:SHEWANA3_1234-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00378
- InterPro:   IPR003753
- InterPro:   IPR020579
- InterPro:   IPR004365
- TIGRFAMs:   TIGR00237

Pfam domain/function: PF02601 Exonuc_VII_L; PF01336 tRNA_anti

EC number: =3.1.11.6

Molecular weight: Translated: 49982; Mature: 49982

Theoretical pI: Translated: 8.97; Mature: 8.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQVPKNNIYTVSRLNGEVRQILEGQLGKVWLNGEISNFSAPSSGHWYLTLKDHYSQIRCA
CCCCCCCCEEEECCCHHHHHHHCCCCCEEEECCCCCCCCCCCCCEEEEEECCHHHHHHHH
MFKGRNQSVSFKPVNGQQVLVKGAISVYEPRGDYQLLIESMLPAGDGLLAQQFEALKMKL
HHCCCCCCEEEECCCCCEEEEEECHHEECCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHH
AAQGLFAADTKRQLPKNIQRIGVITSPTGAAIRDVLHVLARRDPSIEVIIYPTQVQGENA
HHCCHHHHHHHHHHHHHHHHCCCEECCCCHHHHHHHHHHHCCCCCEEEEEEECEECCCCC
DMNICQAINIANQRLEVDVLLLTRGGGSLEDLWCFNSEALAHTIYNSALPVVSAVGHEVD
CHHHHHHHHHHCCEEEEEEEEEECCCCCCHHHEECCCHHHHHHHHHHHHHHHHHHCCHHH
TTISDYVADVRAPTPSAGAELLSQDSDNKSQRLATVLSRLKQSASHYQLKQEKRLSLLEH
HHHHHHHHHHCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RLQRLDPKRTLQQFEQRFDEMQLRLEAALSNKLHGLSRRQQQLANRLEQQSPKHKLALET
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEH
NRLSYLATRLQDAMQDTLNQSEQRITYAAHQLETVSPLATLSRGYSITTDANNQVIDNAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCHHHCCHH
QLSVGDKINTRLRHGQVQSTVTQITDES
HHCCCCHHHHHHHCCHHHHHHHHHCCCC
>Mature Secondary Structure
MQVPKNNIYTVSRLNGEVRQILEGQLGKVWLNGEISNFSAPSSGHWYLTLKDHYSQIRCA
CCCCCCCCEEEECCCHHHHHHHCCCCCEEEECCCCCCCCCCCCCEEEEEECCHHHHHHHH
MFKGRNQSVSFKPVNGQQVLVKGAISVYEPRGDYQLLIESMLPAGDGLLAQQFEALKMKL
HHCCCCCCEEEECCCCCEEEEEECHHEECCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHH
AAQGLFAADTKRQLPKNIQRIGVITSPTGAAIRDVLHVLARRDPSIEVIIYPTQVQGENA
HHCCHHHHHHHHHHHHHHHHCCCEECCCCHHHHHHHHHHHCCCCCEEEEEEECEECCCCC
DMNICQAINIANQRLEVDVLLLTRGGGSLEDLWCFNSEALAHTIYNSALPVVSAVGHEVD
CHHHHHHHHHHCCEEEEEEEEEECCCCCCHHHEECCCHHHHHHHHHHHHHHHHHHCCHHH
TTISDYVADVRAPTPSAGAELLSQDSDNKSQRLATVLSRLKQSASHYQLKQEKRLSLLEH
HHHHHHHHHHCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RLQRLDPKRTLQQFEQRFDEMQLRLEAALSNKLHGLSRRQQQLANRLEQQSPKHKLALET
HHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEH
NRLSYLATRLQDAMQDTLNQSEQRITYAAHQLETVSPLATLSRGYSITTDANNQVIDNAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCHHHCCHH
QLSVGDKINTRLRHGQVQSTVTQITDES
HHCCCCHHHHHHHCCHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA