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The map label for this gene is gpwA [H]

Identifier: 117919646

GI number: 117919646

Start: 1404235

End: 1404846

Strand: Direct

Name: gpwA [H]

Synonym: Shewana3_1197

Alternate gene names: 117919646

Gene position: 1404235-1404846 (Clockwise)

Preceding gene: 117919645

Following gene: 117919647

Centisome position: 28.24

GC content: 44.44

Gene sequence:

>612_bases
ATGATCTCTATATTAGTGAGTGACGTAATAGAGAATAACGAGTTTGCCAATCTTGGCGCGCCCAATGAGAAGGACATTAT
GATGAAACTCCCCTTAGTTATCTTTGCCAGCCTGTTAAGCACTAGCGCATTTGCGGCAACTTGCCCGAGTTATCTTGATG
TTGAAGTGCGTAAATTACACTCGGATGAGAAGATTAATCTGTGTGAATTGACTCAGGGCAAGCCAGTGTTACTGGTCAAC
ACCGCGAGTAACTGTGGTTACACTCCGCAATTTAAGGCCCTCGAAGCGCTCCATAAAGAATACAAAGACAAAGGCTTAGT
GGTGATTGGTTTCCCTTCCGATGACTTTTTCCAAGAAGAAAATGATGAAAAAGACACGGCTAAGGTGTGCTACATCAACT
ATGGTGTCACCTTTACTATGCTCGCTACATCGCCCGTGAGAGGCAGCGATGCTAACAGTGTCTTCAAATACTTAGGAGAT
AAAGCCGACTCGCCTAAGTGGAACTTCTACAAGTATGTCGTCAGTGGCGATGGCAATACTGTGCAGCAGTTTAATTCTAA
GGTTAAACCCGATAGCGCCGAGCTTAAGCAGGCAATAGAATCAGTGCTTTAA

Upstream 100 bases:

>100_bases
AATCCTGTCCGCGGTGATGTGAAAGCAGCTCCCTTGAGCTGCTTTTTTTATCGCTTAAGACAATCGATAACTCGCTGTAG
CTTTTATTTTTTTATTCAAT

Downstream 100 bases:

>100_bases
TGCCCAATTTATTCATTTTACTCATGTTAAGAGGCTACTTTGGCTAGGTTTTCAGGATTATCAAAAGAGATGGGTCACGC
AAAGCGTGGCAAAGTGGGCG

Product: glutathione peroxidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 203; Mature: 203

Protein sequence:

>203_residues
MISILVSDVIENNEFANLGAPNEKDIMMKLPLVIFASLLSTSAFAATCPSYLDVEVRKLHSDEKINLCELTQGKPVLLVN
TASNCGYTPQFKALEALHKEYKDKGLVVIGFPSDDFFQEENDEKDTAKVCYINYGVTFTMLATSPVRGSDANSVFKYLGD
KADSPKWNFYKYVVSGDGNTVQQFNSKVKPDSAELKQAIESVL

Sequences:

>Translated_203_residues
MISILVSDVIENNEFANLGAPNEKDIMMKLPLVIFASLLSTSAFAATCPSYLDVEVRKLHSDEKINLCELTQGKPVLLVN
TASNCGYTPQFKALEALHKEYKDKGLVVIGFPSDDFFQEENDEKDTAKVCYINYGVTFTMLATSPVRGSDANSVFKYLGD
KADSPKWNFYKYVVSGDGNTVQQFNSKVKPDSAELKQAIESVL
>Mature_203_residues
MISILVSDVIENNEFANLGAPNEKDIMMKLPLVIFASLLSTSAFAATCPSYLDVEVRKLHSDEKINLCELTQGKPVLLVN
TASNCGYTPQFKALEALHKEYKDKGLVVIGFPSDDFFQEENDEKDTAKVCYINYGVTFTMLATSPVRGSDANSVFKYLGD
KADSPKWNFYKYVVSGDGNTVQQFNSKVKPDSAELKQAIESVL

Specific function: Not Essential For B12 Transport; However, It Is An Auxiliary Component Of The Transport System. [C]

COG id: COG0386

COG function: function code O; Glutathione peroxidase

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutathione peroxidase family [H]

Homologues:

Organism=Homo sapiens, GI15618997, Length=128, Percent_Identity=35.15625, Blast_Score=79, Evalue=2e-15,
Organism=Homo sapiens, GI192455698, Length=139, Percent_Identity=32.3741007194245, Blast_Score=78, Evalue=4e-15,
Organism=Homo sapiens, GI4557629, Length=161, Percent_Identity=29.8136645962733, Blast_Score=67, Evalue=1e-11,
Organism=Escherichia coli, GI1788003, Length=168, Percent_Identity=28.5714285714286, Blast_Score=86, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17535473, Length=139, Percent_Identity=32.3741007194245, Blast_Score=67, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17506887, Length=163, Percent_Identity=30.0613496932515, Blast_Score=63, Evalue=9e-11,
Organism=Saccharomyces cerevisiae, GI6319721, Length=161, Percent_Identity=42.2360248447205, Blast_Score=120, Evalue=1e-28,
Organism=Saccharomyces cerevisiae, GI6322228, Length=139, Percent_Identity=41.726618705036, Blast_Score=113, Evalue=2e-26,
Organism=Saccharomyces cerevisiae, GI6322826, Length=139, Percent_Identity=38.8489208633094, Blast_Score=96, Evalue=3e-21,
Organism=Drosophila melanogaster, GI24656772, Length=146, Percent_Identity=30.8219178082192, Blast_Score=66, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24656767, Length=146, Percent_Identity=30.8219178082192, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24656777, Length=146, Percent_Identity=30.8219178082192, Blast_Score=65, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000889
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00255 GSHPx [H]

EC number: =1.11.1.9 [H]

Molecular weight: Translated: 22457; Mature: 22457

Theoretical pI: Translated: 4.65; Mature: 4.65

Prosite motif: PS00460 GLUTATHIONE_PEROXID_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISILVSDVIENNEFANLGAPNEKDIMMKLPLVIFASLLSTSAFAATCPSYLDVEVRKLH
CCEEEEHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHC
SDEKINLCELTQGKPVLLVNTASNCGYTPQFKALEALHKEYKDKGLVVIGFPSDDFFQEE
CCCCCCEEEECCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHCCCEEEEECCCCHHHCCC
NDEKDTAKVCYINYGVTFTMLATSPVRGSDANSVFKYLGDKADSPKWNFYKYVVSGDGNT
CCCCCCEEEEEEECCEEEEEEEECCCCCCCHHHHHHHHCCCCCCCCCEEEEEEEECCCCH
VQQFNSKVKPDSAELKQAIESVL
HHHHCCCCCCCHHHHHHHHHHCC
>Mature Secondary Structure
MISILVSDVIENNEFANLGAPNEKDIMMKLPLVIFASLLSTSAFAATCPSYLDVEVRKLH
CCEEEEHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHC
SDEKINLCELTQGKPVLLVNTASNCGYTPQFKALEALHKEYKDKGLVVIGFPSDDFFQEE
CCCCCCEEEECCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHCCCEEEEECCCCHHHCCC
NDEKDTAKVCYINYGVTFTMLATSPVRGSDANSVFKYLGDKADSPKWNFYKYVVSGDGNT
CCCCCCEEEEEEECCEEEEEEEECCCCCCCHHHHHHHHCCCCCCCCCEEEEEEEECCCCH
VQQFNSKVKPDSAELKQAIESVL
HHHHCCCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA