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The map label for this gene is nrdR [H]

Identifier: 117919544

GI number: 117919544

Start: 1289882

End: 1290331

Strand: Direct

Name: nrdR [H]

Synonym: Shewana3_1095

Alternate gene names: 117919544

Gene position: 1289882-1290331 (Clockwise)

Preceding gene: 117919543

Following gene: 117919545

Centisome position: 25.94

GC content: 49.33

Gene sequence:

>450_bases
ATGCATTGTCCATTTTGCAGCGCGACAGATACTAAAGTGATCGATTCCCGATTAGTGGCGGAAGGCCATCAAGTGCGTCG
TCGCCGAGAATGCACCGAATGCCACGAAAGATTTACTACCTTCGAAGGGGCAGAATTAGTCATGCCACGGGTGATTAAAC
GCGATGGTACGCGCCAACCCTTCGATGAAGAAAAGCTGCAAGCAGGTATGTTACGCGCGGTCGAAAAGCGCCCCGTGTCT
ATGGATGAAATCGAGCAGGCCTTAAGTAAAATCAAGTCAACGCTGCGGGCTACTGGTGAGCGCGAAGTGCCATCCGAGAT
GATAGGTAACTTGATGATGGAACAGTTAATGAGCCTAGATAAGGTTGCCTATATTCGTTTTGCCTCGGTTTATCGCGCCT
TTGAAGACGTCTCCGAATTTGGTGAGGCGATTGCGAAACTGCAAAAGTAA

Upstream 100 bases:

>100_bases
CGGCCATTTTTATTGCTAAAATCTTAGACTTAAACCCGCTCGGTTTAAGCGAGAAACAGCGAAAGCCATAGGCTTTATTC
CATTCACGGCAGGAGGCTCA

Downstream 100 bases:

>100_bases
CGTGGGTTATCTTAGGTTAGTGCTTAGGTTAGCGCCTTGTTCGGGCACGCTTCCTCAAGATTTCATAGGGTTTATATGAA
TTGGTCAGAACTCGATAACC

Product: transcriptional regulator NrdR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 149; Mature: 149

Protein sequence:

>149_residues
MHCPFCSATDTKVIDSRLVAEGHQVRRRRECTECHERFTTFEGAELVMPRVIKRDGTRQPFDEEKLQAGMLRAVEKRPVS
MDEIEQALSKIKSTLRATGEREVPSEMIGNLMMEQLMSLDKVAYIRFASVYRAFEDVSEFGEAIAKLQK

Sequences:

>Translated_149_residues
MHCPFCSATDTKVIDSRLVAEGHQVRRRRECTECHERFTTFEGAELVMPRVIKRDGTRQPFDEEKLQAGMLRAVEKRPVS
MDEIEQALSKIKSTLRATGEREVPSEMIGNLMMEQLMSLDKVAYIRFASVYRAFEDVSEFGEAIAKLQK
>Mature_149_residues
MHCPFCSATDTKVIDSRLVAEGHQVRRRRECTECHERFTTFEGAELVMPRVIKRDGTRQPFDEEKLQAGMLRAVEKRPVS
MDEIEQALSKIKSTLRATGEREVPSEMIGNLMMEQLMSLDKVAYIRFASVYRAFEDVSEFGEAIAKLQK

Specific function: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes [H]

COG id: COG1327

COG function: function code K; Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-cone domain [H]

Homologues:

Organism=Escherichia coli, GI1786615, Length=148, Percent_Identity=74.3243243243243, Blast_Score=234, Evalue=1e-63,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005144
- InterPro:   IPR003796 [H]

Pfam domain/function: PF03477 ATP-cone [H]

EC number: NA

Molecular weight: Translated: 17102; Mature: 17102

Theoretical pI: Translated: 6.77; Mature: 6.77

Prosite motif: PS51161 ATP_CONE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
5.4 %Met     (Translated Protein)
8.1 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
5.4 %Met     (Mature Protein)
8.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHCPFCSATDTKVIDSRLVAEGHQVRRRRECTECHERFTTFEGAELVMPRVIKRDGTRQP
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCC
FDEEKLQAGMLRAVEKRPVSMDEIEQALSKIKSTLRATGEREVPSEMIGNLMMEQLMSLD
CCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
KVAYIRFASVYRAFEDVSEFGEAIAKLQK
HHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MHCPFCSATDTKVIDSRLVAEGHQVRRRRECTECHERFTTFEGAELVMPRVIKRDGTRQP
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCC
FDEEKLQAGMLRAVEKRPVSMDEIEQALSKIKSTLRATGEREVPSEMIGNLMMEQLMSLD
CCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
KVAYIRFASVYRAFEDVSEFGEAIAKLQK
HHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA