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The map label for this gene is ipk [H]

Identifier: 117919218

GI number: 117919218

Start: 888596

End: 889450

Strand: Reverse

Name: ipk [H]

Synonym: Shewana3_0766

Alternate gene names: 117919218

Gene position: 889450-888596 (Counterclockwise)

Preceding gene: 117919219

Following gene: 117919217

Centisome position: 17.89

GC content: 51.11

Gene sequence:

>855_bases
ATGTCGAATGAGATTTCACGCAACTGGCCCGCGCCCGCCAAATTAAATCTGTTTTTGCATATCAACGGGCGCCGCGCCGA
CGGTTACCATGAGTTGCAAACCCTGTTTCAATTTATCGATTGTTGCGATCAACTCGATTTTAGGGTGACGCAGACGCCTG
AGCTGATATTGCACTCGAACATGTCGGCCGTTGTCGCCGATAGCGATAACTTAATTCTGCGAGCCGCAAAATCATTACAG
CAAGCGACAAGTTATCCTGGCGGCGCCGAAATCTGGCTCGAAAAACGTTTACCCATGGGCGGTGGTTTAGGTGGCGGCTC
CTCCGATGCGGCCACCACACTCGTGGCCTTAAATCAGTTGTGGAACACCCAATTATCTAACGATGAATTAGCGGCGATTG
GTTTAAAACTCGGTGCCGATATCCCTGTTTTTATTCGCGGTTTCGCGGCATTTGCCGAAGGCGTTGGCGAACGTTTACAG
GCGGTGACGCCCACTGAATTTTGGTATTTAGTGATAGCGCCCGATGCCCATGTCTCCACCGCTGCGGTGTTCCAAGATCC
TTTGCTACCCCGCAATACACCTAAGCTTGGCATCGACACCTTAATGAGCCAACCTTGGGCAAATGATTGCCAAGATCTGG
TCGTTTCCAAATACCCTCAAGTTGCCAAGGCCTTAGGCTGGCTGCTAGAATATGCGCCGTCGAGAATGACCGGAACGGGC
GCATGCGTGTTTGGGGAGTTTTCTTCGCAGCAGCAAGCTCTCGCAGCCTTGGCGAAATTACCGTCTGATATGCAAGGATT
TGTTGCAAAAGGGATGAATATTTCGCCGCTCATAGTGCGACTCACTCATCCATAA

Upstream 100 bases:

>100_bases
CAGTTAAAGCTTGAACGTGGTGATTTACAGCTCAAGCTGCAACTCAATCAATGGCAAGCCTTAGGTAAACCCTCAATACT
GCTCGGAGAAAAACCTTAGC

Downstream 100 bases:

>100_bases
ACTACTTTCTTCTAGAGCAACTTTTTACGATAGCCCACGGGTTCCGCTCCCGTCCCCGCATCGTCGTTGCTCTAGCCACT
AAAATATAAAGCAAACGCCT

Product: 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase

Products: NA

Alternate protein names: CMK; 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase [H]

Number of amino acids: Translated: 284; Mature: 283

Protein sequence:

>284_residues
MSNEISRNWPAPAKLNLFLHINGRRADGYHELQTLFQFIDCCDQLDFRVTQTPELILHSNMSAVVADSDNLILRAAKSLQ
QATSYPGGAEIWLEKRLPMGGGLGGGSSDAATTLVALNQLWNTQLSNDELAAIGLKLGADIPVFIRGFAAFAEGVGERLQ
AVTPTEFWYLVIAPDAHVSTAAVFQDPLLPRNTPKLGIDTLMSQPWANDCQDLVVSKYPQVAKALGWLLEYAPSRMTGTG
ACVFGEFSSQQQALAALAKLPSDMQGFVAKGMNISPLIVRLTHP

Sequences:

>Translated_284_residues
MSNEISRNWPAPAKLNLFLHINGRRADGYHELQTLFQFIDCCDQLDFRVTQTPELILHSNMSAVVADSDNLILRAAKSLQ
QATSYPGGAEIWLEKRLPMGGGLGGGSSDAATTLVALNQLWNTQLSNDELAAIGLKLGADIPVFIRGFAAFAEGVGERLQ
AVTPTEFWYLVIAPDAHVSTAAVFQDPLLPRNTPKLGIDTLMSQPWANDCQDLVVSKYPQVAKALGWLLEYAPSRMTGTG
ACVFGEFSSQQQALAALAKLPSDMQGFVAKGMNISPLIVRLTHP
>Mature_283_residues
SNEISRNWPAPAKLNLFLHINGRRADGYHELQTLFQFIDCCDQLDFRVTQTPELILHSNMSAVVADSDNLILRAAKSLQQ
ATSYPGGAEIWLEKRLPMGGGLGGGSSDAATTLVALNQLWNTQLSNDELAAIGLKLGADIPVFIRGFAAFAEGVGERLQA
VTPTEFWYLVIAPDAHVSTAAVFQDPLLPRNTPKLGIDTLMSQPWANDCQDLVVSKYPQVAKALGWLLEYAPSRMTGTGA
CVFGEFSSQQQALAALAKLPSDMQGFVAKGMNISPLIVRLTHP

Specific function: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol [H]

COG id: COG1947

COG function: function code I; 4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GHMP kinase family. IspE subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787459, Length=275, Percent_Identity=54.9090909090909, Blast_Score=281, Evalue=3e-77,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006204
- InterPro:   IPR013750
- InterPro:   IPR004424
- InterPro:   IPR020568
- InterPro:   IPR014721 [H]

Pfam domain/function: PF08544 GHMP_kinases_C; PF00288 GHMP_kinases_N [H]

EC number: =2.7.1.148 [H]

Molecular weight: Translated: 30767; Mature: 30635

Theoretical pI: Translated: 5.29; Mature: 5.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNEISRNWPAPAKLNLFLHINGRRADGYHELQTLFQFIDCCDQLDFRVTQTPELILHSN
CCCCCCCCCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCEECCCCCEEEECC
MSAVVADSDNLILRAAKSLQQATSYPGGAEIWLEKRLPMGGGLGGGSSDAATTLVALNQL
CEEEEECCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHH
WNTQLSNDELAAIGLKLGADIPVFIRGFAAFAEGVGERLQAVTPTEFWYLVIAPDAHVST
HCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHH
AAVFQDPLLPRNTPKLGIDTLMSQPWANDCQDLVVSKYPQVAKALGWLLEYAPSRMTGTG
HHHHHCCCCCCCCCCCCHHHHHCCCCCCHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCC
ACVFGEFSSQQQALAALAKLPSDMQGFVAKGMNISPLIVRLTHP
EEEECCCCCHHHHHHHHHHCCCHHHHHHHCCCCCCEEEEEEECC
>Mature Secondary Structure 
SNEISRNWPAPAKLNLFLHINGRRADGYHELQTLFQFIDCCDQLDFRVTQTPELILHSN
CCCCCCCCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCEECCCCCEEEECC
MSAVVADSDNLILRAAKSLQQATSYPGGAEIWLEKRLPMGGGLGGGSSDAATTLVALNQL
CEEEEECCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHH
WNTQLSNDELAAIGLKLGADIPVFIRGFAAFAEGVGERLQAVTPTEFWYLVIAPDAHVST
HCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHH
AAVFQDPLLPRNTPKLGIDTLMSQPWANDCQDLVVSKYPQVAKALGWLLEYAPSRMTGTG
HHHHHCCCCCCCCCCCCHHHHHCCCCCCHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCC
ACVFGEFSSQQQALAALAKLPSDMQGFVAKGMNISPLIVRLTHP
EEEECCCCCHHHHHHHHHHCCCHHHHHHHCCCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12368813 [H]