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The map label for this gene is torS [H]

Identifier: 117919188

GI number: 117919188

Start: 855172

End: 856803

Strand: Reverse

Name: torS [H]

Synonym: Shewana3_0736

Alternate gene names: 117919188

Gene position: 856803-855172 (Counterclockwise)

Preceding gene: 117919190

Following gene: 117919186

Centisome position: 17.23

GC content: 44.73

Gene sequence:

>1632_bases
ATGCCGACTTTCTTTAGCCAATTTATTAAAAGCCCGATAGGCAGGCATCTCACCTTGTCTATTATCCTCTTTAGCTCCCT
CATCACCTTAGTGACAACGGCCTATCAGTTGATTAACGACTATCGCGGCGATGTGACTCGTATTGATCGCGTATTCTCCA
ATATTGAAAAAGCCAACCTCGATGTACTCGCCGCCAGCATTTGGGTTATCGATGAAAGACTGATTAATACCCAGTTGAAT
GGTTTAATCCAACTACCTGATATTAATTATATTTCGATAAAAGATGATAGCGGCCAATCGTGGAACGCCGGCAATGAGAA
GCCAACCCATACTCTCAATAAAGTATTTCCTTTGGTGTATAAGTCGCCAACTGACAGCATTAATGTCGGCACTTTAGAGG
TTCAAGTGGATATGGATGCCATTTACCAACGCCTCTACGATAAAGCCATTCTGATCTTGCTCTCTAATGCGATAAAAACC
TTCTTAGTTGCTGGATTTATTCTGTTTTTAGTCTGGTACAACATCACTAAACACTTAGACAAACTCAGTAATTACTGCAA
ACGCATCGATCTCGATACCGATGTCGAGCCATTAGCCTTCGATCGCAAGCAAAAAGTCGATGAATTTACCCAAGTTGCCG
ATGCCATCAACAATATGCAATCGCAACTGCGCGGCTCATTTGAAGCCTTAAAACGCTCTAAAACCGAATTGCAAACCGCC
TTAGAGGATAGAGAACGCTTACTGACGCTCGAGCGCAGTTATAAGGAAGAACTCGCAAGGCAAGTCAAAGAAAGAACACA
GGAATTAGAGCAATCATTAACTGCGCTGAAACGGGCGCAGCAAGTATTGGTCGAGCAGGAAAAAATGGCGGCATTGGGTG
GTTTAGTCTCGGGAGTGGCCCATGAGATCAATACACCGATCGGCATTTGTTTGACGGCGGCCAGTACCCAACTGAGCCAT
ATCGAAGAGCTTATCGAGCTTATACATAGCGAGCATGCCACCCTAGATGAAATCAACGCCATTTTAGATGAGTACCAAGA
AAGCTGTGAGTTGATAGTTCGTAATATCAGTAAGGCCAGTAGCCTGATCCAAAAATTTAAAACGATCGCCATCGACCGTA
GCCACGAAGAACATCAATGCATCAATCTGCAACGTCAGCTTAAGGAGATTTTAGAATCGACCTTAATTATGTATCCCAAG
GTGAAAGCCCAAACTCAGCTACAGGTTAATTCTGCGCTCAACATTCAGACCAATGTCAGCCTGCTCAATCAAATCGTCAG
TAATATTCTCTCTAATGCCTTCACCCATGCCTTTCAGGATAGAGAAGATAATCTGATCCAAATTACGGCCAAGCTAGAGC
AAGACTACGTGAATATCAGCATTGAAAACAATGGGATTGCCATTCCACCCGAGGTGGCAGAGCATATGTTTGAGCCCTTC
TTTACCACCAGCAGGAGTAAAGGAGGCACAGGCTTAGGCTTATCCGCCGCCTTCAATGCCGCCACGCTGCTAAAGGGCAC
CATGAACTATCAAGCAGACTCACAACTGGGCGGCGCACAATTTAATATCCGCATTCCCCTCACCCAATGCGATTCGCCCA
AACTCACCACACACCATGACTTTACGATTTGA

Upstream 100 bases:

>100_bases
CAAAATTGCGGGATATTTCATGGGGATAAAATGCACAATCTGGATGCTTGAGTCTATGCTTATAAGCATCCAACTCGCTA
TTAGCTATAGATAATTTAAG

Downstream 100 bases:

>100_bases
TGGAGTGTTTAATACGAGTTTGATGGCAAGTGGAGCCTGTGGAAGGCGAATAAAGCAAACTCTGGTGCCACTAAACAAAA
ATCCACAGCATTGGCTGTGG

Product: ATPase domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 543; Mature: 542

Protein sequence:

>543_residues
MPTFFSQFIKSPIGRHLTLSIILFSSLITLVTTAYQLINDYRGDVTRIDRVFSNIEKANLDVLAASIWVIDERLINTQLN
GLIQLPDINYISIKDDSGQSWNAGNEKPTHTLNKVFPLVYKSPTDSINVGTLEVQVDMDAIYQRLYDKAILILLSNAIKT
FLVAGFILFLVWYNITKHLDKLSNYCKRIDLDTDVEPLAFDRKQKVDEFTQVADAINNMQSQLRGSFEALKRSKTELQTA
LEDRERLLTLERSYKEELARQVKERTQELEQSLTALKRAQQVLVEQEKMAALGGLVSGVAHEINTPIGICLTAASTQLSH
IEELIELIHSEHATLDEINAILDEYQESCELIVRNISKASSLIQKFKTIAIDRSHEEHQCINLQRQLKEILESTLIMYPK
VKAQTQLQVNSALNIQTNVSLLNQIVSNILSNAFTHAFQDREDNLIQITAKLEQDYVNISIENNGIAIPPEVAEHMFEPF
FTTSRSKGGTGLGLSAAFNAATLLKGTMNYQADSQLGGAQFNIRIPLTQCDSPKLTTHHDFTI

Sequences:

>Translated_543_residues
MPTFFSQFIKSPIGRHLTLSIILFSSLITLVTTAYQLINDYRGDVTRIDRVFSNIEKANLDVLAASIWVIDERLINTQLN
GLIQLPDINYISIKDDSGQSWNAGNEKPTHTLNKVFPLVYKSPTDSINVGTLEVQVDMDAIYQRLYDKAILILLSNAIKT
FLVAGFILFLVWYNITKHLDKLSNYCKRIDLDTDVEPLAFDRKQKVDEFTQVADAINNMQSQLRGSFEALKRSKTELQTA
LEDRERLLTLERSYKEELARQVKERTQELEQSLTALKRAQQVLVEQEKMAALGGLVSGVAHEINTPIGICLTAASTQLSH
IEELIELIHSEHATLDEINAILDEYQESCELIVRNISKASSLIQKFKTIAIDRSHEEHQCINLQRQLKEILESTLIMYPK
VKAQTQLQVNSALNIQTNVSLLNQIVSNILSNAFTHAFQDREDNLIQITAKLEQDYVNISIENNGIAIPPEVAEHMFEPF
FTTSRSKGGTGLGLSAAFNAATLLKGTMNYQADSQLGGAQFNIRIPLTQCDSPKLTTHHDFTI
>Mature_542_residues
PTFFSQFIKSPIGRHLTLSIILFSSLITLVTTAYQLINDYRGDVTRIDRVFSNIEKANLDVLAASIWVIDERLINTQLNG
LIQLPDINYISIKDDSGQSWNAGNEKPTHTLNKVFPLVYKSPTDSINVGTLEVQVDMDAIYQRLYDKAILILLSNAIKTF
LVAGFILFLVWYNITKHLDKLSNYCKRIDLDTDVEPLAFDRKQKVDEFTQVADAINNMQSQLRGSFEALKRSKTELQTAL
EDRERLLTLERSYKEELARQVKERTQELEQSLTALKRAQQVLVEQEKMAALGGLVSGVAHEINTPIGICLTAASTQLSHI
EELIELIHSEHATLDEINAILDEYQESCELIVRNISKASSLIQKFKTIAIDRSHEEHQCINLQRQLKEILESTLIMYPKV
KAQTQLQVNSALNIQTNVSLLNQIVSNILSNAFTHAFQDREDNLIQITAKLEQDYVNISIENNGIAIPPEVAEHMFEPFF
TTSRSKGGTGLGLSAAFNAATLLKGTMNYQADSQLGGAQFNIRIPLTQCDSPKLTTHHDFTI

Specific function: Member of the two-component regulatory system torS/torR involved in the anaerobic utilization of trimethylamine-N-oxide (TMAO). Detects the presence of TMAO in the medium and, in response, activates torR via a four-step phosphorelay. When TMAO is removed,

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI87081816, Length=379, Percent_Identity=26.1213720316623, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1788549, Length=228, Percent_Identity=31.140350877193, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1787894, Length=252, Percent_Identity=28.1746031746032, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI145693157, Length=281, Percent_Identity=24.5551601423488, Blast_Score=72, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR014302
- InterPro:   IPR001789 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF01627 Hpt; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 61180; Mature: 61048

Theoretical pI: Translated: 5.36; Mature: 5.36

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTFFSQFIKSPIGRHLTLSIILFSSLITLVTTAYQLINDYRGDVTRIDRVFSNIEKANL
CCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCH
DVLAASIWVIDERLINTQLNGLIQLPDINYISIKDDSGQSWNAGNEKPTHTLNKVFPLVY
HHHHHHHHHHHHHHHHHHHCCEEECCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHC
KSPTDSINVGTLEVQVDMDAIYQRLYDKAILILLSNAIKTFLVAGFILFLVWYNITKHLD
CCCCCCEEEEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KLSNYCKRIDLDTDVEPLAFDRKQKVDEFTQVADAINNMQSQLRGSFEALKRSKTELQTA
HHHHHHHHCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LEDRERLLTLERSYKEELARQVKERTQELEQSLTALKRAQQVLVEQEKMAALGGLVSGVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HEINTPIGICLTAASTQLSHIEELIELIHSEHATLDEINAILDEYQESCELIVRNISKAS
HHHCCCHHEEEEHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
SLIQKFKTIAIDRSHEEHQCINLQRQLKEILESTLIMYPKVKAQTQLQVNSALNIQTNVS
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHEEECCCCCCHHHHH
LLNQIVSNILSNAFTHAFQDREDNLIQITAKLEQDYVNISIENNGIAIPPEVAEHMFEPF
HHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCEEEEEECCCCEECCHHHHHHHHHHH
FTTSRSKGGTGLGLSAAFNAATLLKGTMNYQADSQLGGAQFNIRIPLTQCDSPKLTTHHD
HHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEEEECCCCCCCCCCC
FTI
CCC
>Mature Secondary Structure 
PTFFSQFIKSPIGRHLTLSIILFSSLITLVTTAYQLINDYRGDVTRIDRVFSNIEKANL
CCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCH
DVLAASIWVIDERLINTQLNGLIQLPDINYISIKDDSGQSWNAGNEKPTHTLNKVFPLVY
HHHHHHHHHHHHHHHHHHHCCEEECCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHC
KSPTDSINVGTLEVQVDMDAIYQRLYDKAILILLSNAIKTFLVAGFILFLVWYNITKHLD
CCCCCCEEEEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KLSNYCKRIDLDTDVEPLAFDRKQKVDEFTQVADAINNMQSQLRGSFEALKRSKTELQTA
HHHHHHHHCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LEDRERLLTLERSYKEELARQVKERTQELEQSLTALKRAQQVLVEQEKMAALGGLVSGVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HEINTPIGICLTAASTQLSHIEELIELIHSEHATLDEINAILDEYQESCELIVRNISKAS
HHHCCCHHEEEEHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
SLIQKFKTIAIDRSHEEHQCINLQRQLKEILESTLIMYPKVKAQTQLQVNSALNIQTNVS
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHEEECCCCCCHHHHH
LLNQIVSNILSNAFTHAFQDREDNLIQITAKLEQDYVNISIENNGIAIPPEVAEHMFEPF
HHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCEEEEEECCCCEECCHHHHHHHHHHH
FTTSRSKGGTGLGLSAAFNAATLLKGTMNYQADSQLGGAQFNIRIPLTQCDSPKLTTHHD
HHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEEEECCCCCCCCCCC
FTI
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]