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The map label for this gene is 117919158

Identifier: 117919158

GI number: 117919158

Start: 821103

End: 822182

Strand: Reverse

Name: 117919158

Synonym: Shewana3_0706

Alternate gene names: NA

Gene position: 822182-821103 (Counterclockwise)

Preceding gene: 117919159

Following gene: 117919157

Centisome position: 16.54

GC content: 50.56

Gene sequence:

>1080_bases
ATGCATACCAGCCATATCCCAATCATTCAGCAAGCATCGTTCAATCTACAACCGAGTTTGCTCAAACCTATGGCGCTCAG
CTATGCGCAAATCCTTGAGCTGCTTCAAGGGCAGGACGATGAATGGCTGTTTAGCCGCGCTCAGCTCGCCACTGAGCTCG
AATTTAAGCAACAGGTCTATTTACGGGGCATTGTTGAATTCTCGAATCATTGCCGTAACCACTGCCATTACTGCGGACTG
CGTAGCAAGAATCGGCAGGTAAAGCGTTATCGGCTATCAAACGAAGAAATCCTCAGCGCGGTGAATAACATAGCTGCACT
CGGCCTCGGCACTGTGGTGCTGCAATCGGGGGATGATTTTAGCTACAGTTGTAAGCGCATCAGCGCCCTTATTAGTGAAA
TTAAGCAGCGCCATAACCTAGCAATCACTCTCTCCCTCGGTGATCGCAAACATCATGAGTTGGAAAACTGGCGTGAGGCG
GGTGCCGATCGTTATTTACTCAAGATGGAAACCTTCGACCGCGCACTCTTTGCTCGCTGTCGCCCTAAAGCCCATTTCGA
TGAGCGCATCGCAAGACTTGCTCACCTTAAGTCACTCGGCTTTCAGACAGGTTCCGGCATTATCATCGATTTACCTGGGA
TGACAGATGCGATCTTAGCCCGCGATATTCAATGCTTAACTGAGCTGCAGCTCGATATGCTGGCCTGCGGCCCTTTTATC
GCCCATGCGCAAACTCCATTTGCCACATCGCTCAATGGCAGCGCCCTTAAGAGCCATAGGGTGAGTGCGATTTTGCGACT
GATGAATCCTGGGGCAAATATCCCCGCGACCAGCTCCCTCGATGCACTCGAAAAAGGCACTCGGGAACTGGCACTCAAGC
GAGGCTGCAATGTGATTATGCCTTCCTTTACACCAACACAGGTGAGTGGTGACTACAGCATCTATCCAGGAAAAAACCAG
CAACAACATCCGGCTGCGGAGCGACTTAATCATATCTGCCAGCAAATACAAAGCCATGGGCTAACCCCCTCCTTTAGCCG
TGGTGATTCGAAAAGGACTCAATATGTGTCAAGGCATTAA

Upstream 100 bases:

>100_bases
CGGTAGCAATAACCCTTGGCCGTTACGTAGAAGAATGTCGCCGCGCCGTGGGCGATCTCTGGTATCAAAGTGTGATAGCA
CTGGATAAGGAGCGTCACTG

Downstream 100 bases:

>100_bases
TCCACAAGAGCATTCCCAAAACCAATCGGCACCACGGGGCATGCGTTACCATATCGCCTTAGTCGGTCGACGCAATGCGG
GTAAGTCATCCCTGCTCAAT

Product: biotin synthase

Products: biotin

Alternate protein names: NA

Number of amino acids: Translated: 359; Mature: 359

Protein sequence:

>359_residues
MHTSHIPIIQQASFNLQPSLLKPMALSYAQILELLQGQDDEWLFSRAQLATELEFKQQVYLRGIVEFSNHCRNHCHYCGL
RSKNRQVKRYRLSNEEILSAVNNIAALGLGTVVLQSGDDFSYSCKRISALISEIKQRHNLAITLSLGDRKHHELENWREA
GADRYLLKMETFDRALFARCRPKAHFDERIARLAHLKSLGFQTGSGIIIDLPGMTDAILARDIQCLTELQLDMLACGPFI
AHAQTPFATSLNGSALKSHRVSAILRLMNPGANIPATSSLDALEKGTRELALKRGCNVIMPSFTPTQVSGDYSIYPGKNQ
QQHPAAERLNHICQQIQSHGLTPSFSRGDSKRTQYVSRH

Sequences:

>Translated_359_residues
MHTSHIPIIQQASFNLQPSLLKPMALSYAQILELLQGQDDEWLFSRAQLATELEFKQQVYLRGIVEFSNHCRNHCHYCGL
RSKNRQVKRYRLSNEEILSAVNNIAALGLGTVVLQSGDDFSYSCKRISALISEIKQRHNLAITLSLGDRKHHELENWREA
GADRYLLKMETFDRALFARCRPKAHFDERIARLAHLKSLGFQTGSGIIIDLPGMTDAILARDIQCLTELQLDMLACGPFI
AHAQTPFATSLNGSALKSHRVSAILRLMNPGANIPATSSLDALEKGTRELALKRGCNVIMPSFTPTQVSGDYSIYPGKNQ
QQHPAAERLNHICQQIQSHGLTPSFSRGDSKRTQYVSRH
>Mature_359_residues
MHTSHIPIIQQASFNLQPSLLKPMALSYAQILELLQGQDDEWLFSRAQLATELEFKQQVYLRGIVEFSNHCRNHCHYCGL
RSKNRQVKRYRLSNEEILSAVNNIAALGLGTVVLQSGDDFSYSCKRISALISEIKQRHNLAITLSLGDRKHHELENWREA
GADRYLLKMETFDRALFARCRPKAHFDERIARLAHLKSLGFQTGSGIIIDLPGMTDAILARDIQCLTELQLDMLACGPFI
AHAQTPFATSLNGSALKSHRVSAILRLMNPGANIPATSSLDALEKGTRELALKRGCNVIMPSFTPTQVSGDYSIYPGKNQ
QQHPAAERLNHICQQIQSHGLTPSFSRGDSKRTQYVSRH

Specific function: Unknown

COG id: COG0502

COG function: function code H; Biotin synthase and related enzymes

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR010722
- InterPro:   IPR006638
- InterPro:   IPR007197 [H]

Pfam domain/function: PF06968 BATS; PF04055 Radical_SAM [H]

EC number: 2.8.1.6

Molecular weight: Translated: 40270; Mature: 40270

Theoretical pI: Translated: 9.09; Mature: 9.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHTSHIPIIQQASFNLQPSLLKPMALSYAQILELLQGQDDEWLFSRAQLATELEFKQQVY
CCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
LRGIVEFSNHCRNHCHYCGLRSKNRQVKRYRLSNEEILSAVNNIAALGLGTVVLQSGDDF
HHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHEEECCCCC
SYSCKRISALISEIKQRHNLAITLSLGDRKHHELENWREAGADRYLLKMETFDRALFARC
HHHHHHHHHHHHHHHHHCCEEEEEEECCCHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHC
RPKAHFDERIARLAHLKSLGFQTGSGIIIDLPGMTDAILARDIQCLTELQLDMLACGPFI
CCCCHHHHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCHH
AHAQTPFATSLNGSALKSHRVSAILRLMNPGANIPATSSLDALEKGTRELALKRGCNVIM
HHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEE
PSFTPTQVSGDYSIYPGKNQQQHPAAERLNHICQQIQSHGLTPSFSRGDSKRTQYVSRH
CCCCCCCCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHCCC
>Mature Secondary Structure
MHTSHIPIIQQASFNLQPSLLKPMALSYAQILELLQGQDDEWLFSRAQLATELEFKQQVY
CCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
LRGIVEFSNHCRNHCHYCGLRSKNRQVKRYRLSNEEILSAVNNIAALGLGTVVLQSGDDF
HHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHEEECCCCC
SYSCKRISALISEIKQRHNLAITLSLGDRKHHELENWREAGADRYLLKMETFDRALFARC
HHHHHHHHHHHHHHHHHCCEEEEEEECCCHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHC
RPKAHFDERIARLAHLKSLGFQTGSGIIIDLPGMTDAILARDIQCLTELQLDMLACGPFI
CCCCHHHHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCHH
AHAQTPFATSLNGSALKSHRVSAILRLMNPGANIPATSSLDALEKGTRELALKRGCNVIM
HHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEE
PSFTPTQVSGDYSIYPGKNQQQHPAAERLNHICQQIQSHGLTPSFSRGDSKRTQYVSRH
CCCCCCCCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: dethiobiotin; sulfur

Specific reaction: dethiobiotin + sulfur = biotin

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]