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The map label for this gene is virS [H]

Identifier: 117918759

GI number: 117918759

Start: 338762

End: 339769

Strand: Reverse

Name: virS [H]

Synonym: Shewana3_0302

Alternate gene names: 117918759

Gene position: 339769-338762 (Counterclockwise)

Preceding gene: 117918764

Following gene: 117918757

Centisome position: 6.83

GC content: 52.18

Gene sequence:

>1008_bases
ATGTACCTAGTCCGAAGTGGTGCCGTCGCTCAATTCGAGCAACTGGTCCTAGAATTGGGGGAAAACCCCATAGAAATGAT
CCATCAGGCTGGATTGCGTCAGGCGCAGTTTCGCGATCCCAACACCTATATCGCTTATCCGCGGCTAGCCGAGTTATTGG
AAATTGCTGCGCAGCGCTGTCAGCACCCCTTGTTTGGCTTAATGCTGGCCCAGCGACAAACTTTGCATGTATTGGGTGAT
TTACCTATGCTGGTTTCCCGCGCGGCCACTGTGGCCGATGCGCTGGCCCGCGTGAATGACTATCTGTATCTGCACGCCTC
AGGCGTATCATTACAACTGCAATCTCAGGGTGAAATTGTCCGCCTTGCACTATCGATGAATGTTCACAGCCCTAGGGGCA
TAGAACAACTGATGCAAATGAGCGTGGCGCAGCTGGCAATGTTTGTCTCGAGCCTGCTGAATATCAATATCAGCAACGTT
CCTTTGTATTTATGCCAAAACAAACCCAGCGAACAGGAATCTCAGCGCCTTACCCACTCGGTGCGTTTTCGCGAGCCCTT
TAATGGCGTAGTGGTCAAGGCCTCGCAACTGACGGGGCGTAACTATCACGATGAAGAGGCGCTTAATCGCCACCTCCAGT
CGCACCTGCAATATTTACAGAGCCGCTACCCCGACAATCTTGCCGACCAAGCACGGGACTTAATCCATCGGCTGCTGCCC
ACGGGAGAATGCTGCATCGAAAGGGTATCGACGGCGCTGGGTTTACACGAACGCACCCTACAAACGAGGCTGCAAGAGAC
GGGGCAAAGCTATCGACAATTACTACAGGATGTTCGGCAAAATATCGCCCAACAGCAACTCAGCTACGGCACGCAAACCA
TCACCGAACTCGCACTGCAACTCGGTTATGCCGAAGTCGCCGTATTTAGTCGCCACTTTAAAACTTGGACAGGATTTTCC
CCAAAACAATGGCAACAACAGTATCGTAAGGGGCGAATTGAGGATTGA

Upstream 100 bases:

>100_bases
GACGTTGTTAATTTAGATGGTTAATTGCACATATTCTTGACTTATTACGAGCCAAATTTGATATATTGCGAGTCTTATAA
CAAAGTGAACTAAGCATCCC

Downstream 100 bases:

>100_bases
AGGCTGATAAAAAAGCCCCGCTAAGTTGCCTTAGCGGGGCTTTATTCACTCTGTGTAGTCACTTTACGCGACTACACAAC
CACCATTAGCCGCGGCTAGC

Product: AraC family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 335; Mature: 335

Protein sequence:

>335_residues
MYLVRSGAVAQFEQLVLELGENPIEMIHQAGLRQAQFRDPNTYIAYPRLAELLEIAAQRCQHPLFGLMLAQRQTLHVLGD
LPMLVSRAATVADALARVNDYLYLHASGVSLQLQSQGEIVRLALSMNVHSPRGIEQLMQMSVAQLAMFVSSLLNINISNV
PLYLCQNKPSEQESQRLTHSVRFREPFNGVVVKASQLTGRNYHDEEALNRHLQSHLQYLQSRYPDNLADQARDLIHRLLP
TGECCIERVSTALGLHERTLQTRLQETGQSYRQLLQDVRQNIAQQQLSYGTQTITELALQLGYAEVAVFSRHFKTWTGFS
PKQWQQQYRKGRIED

Sequences:

>Translated_335_residues
MYLVRSGAVAQFEQLVLELGENPIEMIHQAGLRQAQFRDPNTYIAYPRLAELLEIAAQRCQHPLFGLMLAQRQTLHVLGD
LPMLVSRAATVADALARVNDYLYLHASGVSLQLQSQGEIVRLALSMNVHSPRGIEQLMQMSVAQLAMFVSSLLNINISNV
PLYLCQNKPSEQESQRLTHSVRFREPFNGVVVKASQLTGRNYHDEEALNRHLQSHLQYLQSRYPDNLADQARDLIHRLLP
TGECCIERVSTALGLHERTLQTRLQETGQSYRQLLQDVRQNIAQQQLSYGTQTITELALQLGYAEVAVFSRHFKTWTGFS
PKQWQQQYRKGRIED
>Mature_335_residues
MYLVRSGAVAQFEQLVLELGENPIEMIHQAGLRQAQFRDPNTYIAYPRLAELLEIAAQRCQHPLFGLMLAQRQTLHVLGD
LPMLVSRAATVADALARVNDYLYLHASGVSLQLQSQGEIVRLALSMNVHSPRGIEQLMQMSVAQLAMFVSSLLNINISNV
PLYLCQNKPSEQESQRLTHSVRFREPFNGVVVKASQLTGRNYHDEEALNRHLQSHLQYLQSRYPDNLADQARDLIHRLLP
TGECCIERVSTALGLHERTLQTRLQETGQSYRQLLQDVRQNIAQQQLSYGTQTITELALQLGYAEVAVFSRHFKTWTGFS
PKQWQQQYRKGRIED

Specific function: May have a role in the regulation of proteins necessary for virulence [H]

COG id: COG2207

COG function: function code K; AraC-type DNA-binding domain-containing proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH araC/xylS-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR018060 [H]

Pfam domain/function: PF00165 HTH_AraC [H]

EC number: NA

Molecular weight: Translated: 38203; Mature: 38203

Theoretical pI: Translated: 8.03; Mature: 8.03

Prosite motif: PS01124 HTH_ARAC_FAMILY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYLVRSGAVAQFEQLVLELGENPIEMIHQAGLRQAQFRDPNTYIAYPRLAELLEIAAQRC
CCEECCCHHHHHHHHHHHHCCCHHHHHHHHCCHHHHCCCCCCEECCHHHHHHHHHHHHHH
QHPLFGLMLAQRQTLHVLGDLPMLVSRAATVADALARVNDYLYLHASGVSLQLQSQGEIV
CCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHEEEEEECCCEEEECCCCCEE
RLALSMNVHSPRGIEQLMQMSVAQLAMFVSSLLNINISNVPLYLCQNKPSEQESQRLTHS
EEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCHHHHHHHHHH
VRFREPFNGVVVKASQLTGRNYHDEEALNRHLQSHLQYLQSRYPDNLADQARDLIHRLLP
HHHCCCCCCEEEEEHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCC
TGECCIERVSTALGLHERTLQTRLQETGQSYRQLLQDVRQNIAQQQLSYGTQTITELALQ
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGYAEVAVFSRHFKTWTGFSPKQWQQQYRKGRIED
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCC
>Mature Secondary Structure
MYLVRSGAVAQFEQLVLELGENPIEMIHQAGLRQAQFRDPNTYIAYPRLAELLEIAAQRC
CCEECCCHHHHHHHHHHHHCCCHHHHHHHHCCHHHHCCCCCCEECCHHHHHHHHHHHHHH
QHPLFGLMLAQRQTLHVLGDLPMLVSRAATVADALARVNDYLYLHASGVSLQLQSQGEIV
CCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHEEEEEECCCEEEECCCCCEE
RLALSMNVHSPRGIEQLMQMSVAQLAMFVSSLLNINISNVPLYLCQNKPSEQESQRLTHS
EEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCHHHHHHHHHH
VRFREPFNGVVVKASQLTGRNYHDEEALNRHLQSHLQYLQSRYPDNLADQARDLIHRLLP
HHHCCCCCCEEEEEHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCC
TGECCIERVSTALGLHERTLQTRLQETGQSYRQLLQDVRQNIAQQQLSYGTQTITELALQ
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGYAEVAVFSRHFKTWTGFSPKQWQQQYRKGRIED
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8472958; 9634230; 12218036 [H]