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The map label for this gene is kdpD [H]

Identifier: 117918519

GI number: 117918519

Start: 70620

End: 71666

Strand: Reverse

Name: kdpD [H]

Synonym: Shewana3_0060

Alternate gene names: 117918519

Gene position: 71666-70620 (Counterclockwise)

Preceding gene: 117918520

Following gene: 117918518

Centisome position: 1.44

GC content: 52.24

Gene sequence:

>1047_bases
ATGACTTTTGCAAACACAGCCTCCATCAACCAATACTGGCGCACGCACCCCGCGTTATTTACCGCCATGTTGTTAGTGAT
TGCTTTGCTCACAAGCTATTTGATTGATTACTTTTCAGGCTCGGCCATTGCCGTACTGCTTATCCTGCAATTAGCCGTGG
TCGCCGTGGCCCTGCAATGCAGCGCCAACTACGCCTATTTTGTGGCCGTGTTTGGCGCAGTGAGTTTCAATTTTTTATTC
ACCACGCCGCGCTATTCGTTGCAGATGTTCAACGTCGAAGACATAGTCAATCTAAGCGTGTTTTTGCTGGTCGCCCTCAC
TAGCAGCAAGTTAGCCGAACATTACCGCCGCCAGCAGCAGGCACTCGAACAGGCACAGCTCAGAAATAGCATTTTGCTCT
CAGTCTCCCACGATTTACGCACGCCGCTTGCGACCATTATCGGCACCTTAACCACGCTGAAAGAATACCAAGCTAAACTC
AGCCCTAAGCAAAACGAGGAGCTTATTGACTCGGCCGCCGCCGAGAGTCATCGCCTGCACCAATATATCGAAAACCTCTT
GCAGGCGACCAAGTTACAACATGGCGTGCTCAAATTTAGCCTAGACGAAGCCAATCTACGCGAAGTGTTACAGCGTACGA
TTGCCCGCTTTCAAACCGCGCAACCTAGGATCCAAATTCATAGTGAGCCAGAACTTCCGCCATTAATGATTTGCAGCTCT
TTGATTGAACAGGCGATTTTTAATGTGCTCGACAATGCCCTGCGCTACTCGCCCGCAGAACTGCCTGTCACGGTAAACCT
GTACCGCCACCAACAGCTGCTACGCATCGATATTCAAGACTTAGGACAGGGGATAGCGCCAGCCGACGCCGAGGCCATTT
TCGAGCTGTTCTATCGTCAACATCCCTCGACCGATGGCGGTGCGGGATTAGGCCTAGCGGTCGCTAAAGGCATTATTACC
GCCCACAGGGGCAGCATCGGCGCCGAAAGTGTCGCCCAAGGCAGCTTGATCCGCATCGCCTTACCCATAACCACGGAGGC
GGCATAA

Upstream 100 bases:

>100_bases
ATTCACAAGCCAAACCCCAGAAAATTTTACGGATTTTTTACGCGCTATCCCTACAGGCCTTTGCTAGAGTAGCCTTAACT
TCAGCAACGCCTTAGCCGTT

Downstream 100 bases:

>100_bases
ATGGCTTATAAGGTCTTAGTGGTGGATGATGAGCCGCAAATCCATACCTTTATGCGGATCTCACTCGAAGCGGAAGGCTT
TGAATACTTAAGCGCCACCA

Product: ATPase domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 348; Mature: 347

Protein sequence:

>348_residues
MTFANTASINQYWRTHPALFTAMLLVIALLTSYLIDYFSGSAIAVLLILQLAVVAVALQCSANYAYFVAVFGAVSFNFLF
TTPRYSLQMFNVEDIVNLSVFLLVALTSSKLAEHYRRQQQALEQAQLRNSILLSVSHDLRTPLATIIGTLTTLKEYQAKL
SPKQNEELIDSAAAESHRLHQYIENLLQATKLQHGVLKFSLDEANLREVLQRTIARFQTAQPRIQIHSEPELPPLMICSS
LIEQAIFNVLDNALRYSPAELPVTVNLYRHQQLLRIDIQDLGQGIAPADAEAIFELFYRQHPSTDGGAGLGLAVAKGIIT
AHRGSIGAESVAQGSLIRIALPITTEAA

Sequences:

>Translated_348_residues
MTFANTASINQYWRTHPALFTAMLLVIALLTSYLIDYFSGSAIAVLLILQLAVVAVALQCSANYAYFVAVFGAVSFNFLF
TTPRYSLQMFNVEDIVNLSVFLLVALTSSKLAEHYRRQQQALEQAQLRNSILLSVSHDLRTPLATIIGTLTTLKEYQAKL
SPKQNEELIDSAAAESHRLHQYIENLLQATKLQHGVLKFSLDEANLREVLQRTIARFQTAQPRIQIHSEPELPPLMICSS
LIEQAIFNVLDNALRYSPAELPVTVNLYRHQQLLRIDIQDLGQGIAPADAEAIFELFYRQHPSTDGGAGLGLAVAKGIIT
AHRGSIGAESVAQGSLIRIALPITTEAA
>Mature_347_residues
TFANTASINQYWRTHPALFTAMLLVIALLTSYLIDYFSGSAIAVLLILQLAVVAVALQCSANYAYFVAVFGAVSFNFLFT
TPRYSLQMFNVEDIVNLSVFLLVALTSSKLAEHYRRQQQALEQAQLRNSILLSVSHDLRTPLATIIGTLTTLKEYQAKLS
PKQNEELIDSAAAESHRLHQYIENLLQATKLQHGVLKFSLDEANLREVLQRTIARFQTAQPRIQIHSEPELPPLMICSSL
IEQAIFNVLDNALRYSPAELPVTVNLYRHQQLLRIDIQDLGQGIAPADAEAIFELFYRQHPSTDGGAGLGLAVAKGIITA
HRGSIGAESVAQGSLIRIALPITTEAA

Specific function: Member of the two-component regulatory system kdpD/kdpE involved in the regulation of the kdp operon. KdpD may function as a membrane-associated protein kinase that phosphorylates kdpE in response to environmental signals [H]

COG id: COG2205

COG function: function code T; Osmosensitive K+ channel histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1786912, Length=286, Percent_Identity=27.6223776223776, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI145693157, Length=258, Percent_Identity=29.0697674418605, Blast_Score=88, Evalue=8e-19,
Organism=Escherichia coli, GI1788393, Length=247, Percent_Identity=27.9352226720648, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1790346, Length=232, Percent_Identity=32.3275862068966, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1786783, Length=219, Percent_Identity=27.8538812785388, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI1790861, Length=234, Percent_Identity=27.7777777777778, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1788549, Length=248, Percent_Identity=28.6290322580645, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI1787894, Length=215, Percent_Identity=29.3023255813954, Blast_Score=72, Evalue=8e-14,
Organism=Escherichia coli, GI87081816, Length=244, Percent_Identity=27.4590163934426, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI1786600, Length=234, Percent_Identity=26.9230769230769, Blast_Score=68, Evalue=8e-13,
Organism=Escherichia coli, GI1790436, Length=261, Percent_Identity=26.8199233716475, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1789808, Length=221, Percent_Identity=27.1493212669683, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI48994928, Length=222, Percent_Identity=24.7747747747748, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1789149, Length=226, Percent_Identity=26.1061946902655, Blast_Score=62, Evalue=6e-11,
Organism=Escherichia coli, GI1788713, Length=241, Percent_Identity=24.4813278008299, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR014729
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR003852
- InterPro:   IPR006016 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF02702 KdpD; PF00582 Usp [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 38414; Mature: 38283

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTFANTASINQYWRTHPALFTAMLLVIALLTSYLIDYFSGSAIAVLLILQLAVVAVALQC
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
SANYAYFVAVFGAVSFNFLFTTPRYSLQMFNVEDIVNLSVFLLVALTSSKLAEHYRRQQQ
CCCHHHHHHHHHHHHHHEEEECCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALEQAQLRNSILLSVSHDLRTPLATIIGTLTTLKEYQAKLSPKQNEELIDSAAAESHRLH
HHHHHHHHHHHEEEECHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
QYIENLLQATKLQHGVLKFSLDEANLREVLQRTIARFQTAQPRIQIHSEPELPPLMICSS
HHHHHHHHHHHHHHHHHEEECCHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCHHHHHHH
LIEQAIFNVLDNALRYSPAELPVTVNLYRHQQLLRIDIQDLGQGIAPADAEAIFELFYRQ
HHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHEEHHHHCCCCCCCCHHHHHHHHHHH
HPSTDGGAGLGLAVAKGIITAHRGSIGAESVAQGSLIRIALPITTEAA
CCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHCCCCEEEEEECCCCCCC
>Mature Secondary Structure 
TFANTASINQYWRTHPALFTAMLLVIALLTSYLIDYFSGSAIAVLLILQLAVVAVALQC
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
SANYAYFVAVFGAVSFNFLFTTPRYSLQMFNVEDIVNLSVFLLVALTSSKLAEHYRRQQQ
CCCHHHHHHHHHHHHHHEEEECCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALEQAQLRNSILLSVSHDLRTPLATIIGTLTTLKEYQAKLSPKQNEELIDSAAAESHRLH
HHHHHHHHHHHEEEECHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
QYIENLLQATKLQHGVLKFSLDEANLREVLQRTIARFQTAQPRIQIHSEPELPPLMICSS
HHHHHHHHHHHHHHHHHEEECCHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCHHHHHHH
LIEQAIFNVLDNALRYSPAELPVTVNLYRHQQLLRIDIQDLGQGIAPADAEAIFELFYRQ
HHHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHEEHHHHCCCCCCCCHHHHHHHHHHH
HPSTDGGAGLGLAVAKGIITAHRGSIGAESVAQGSLIRIALPITTEAA
CCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHCCCCEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9226259; 11466286 [H]