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The map label for this gene is kdpE [H]

Identifier: 117918518

GI number: 117918518

Start: 69930

End: 70619

Strand: Reverse

Name: kdpE [H]

Synonym: Shewana3_0059

Alternate gene names: 117918518

Gene position: 70619-69930 (Counterclockwise)

Preceding gene: 117918519

Following gene: 117918517

Centisome position: 1.42

GC content: 53.33

Gene sequence:

>690_bases
ATGGCTTATAAGGTCTTAGTGGTGGATGATGAGCCGCAAATCCATACCTTTATGCGGATCTCACTCGAAGCGGAAGGCTT
TGAATACTTAAGCGCCACCAGCATAACCACGGCGCTTAAACAATATCAAAGCCACCAGCCGCACCTTATCGTGCTCGACC
TCGGCCTGCCCGATGGCGATGGTATCGAATTGCTCCATGGGCTACGCCAGCAGGATAAGACCCCAGTGCTGGTGCTCACC
GCCCGCGATCAGGAGGAAGAAAAAATCCGCCTGCTCGAGGCAGGCGCTAACGATTACCTGAGTAAGCCCTTTGGCATCAG
GGAATTAATCGTGCGTATCAAGGTATTAGTCCGCGACCTTGTGGATACCTCAAGCACCATCGATATGCTGCAATTTGGCC
CGCTCACCCTACAAAAGAGCAGCCATCAATGCTGGCTGAATCAACAGGAAGTGGCGCTCACTAAAAAGGAATTTGCCCTG
CTCGCCCAACTCATGTCCCACCCGGGGCAATTACTGAAACAGAGCGATCTGCTGCGCAATATCTGGGGCGAGACTCACCA
AGAAGATAGCCACTATCTACGGATTTTAGTCCGCCAGCTGCGTAAAAAGCTCAACGACAGCGACGAACAACAGCTGATCA
AAACCGAGCCCGGCTTAGGGTATCGACTCACCGACCTCGGCCCGCCCTAG

Upstream 100 bases:

>100_bases
AGGCATTATTACCGCCCACAGGGGCAGCATCGGCGCCGAAAGTGTCGCCCAAGGCAGCTTGATCCGCATCGCCTTACCCA
TAACCACGGAGGCGGCATAA

Downstream 100 bases:

>100_bases
GCCAGCTCGCCTCACTCTTTAGCTCAACCACAAAAGGATATGAAATGGCACATTTTACTGTCATCGGATTAGGCCGCTTC
GGCGTTGCCGCGAGCCTCGA

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 229; Mature: 228

Protein sequence:

>229_residues
MAYKVLVVDDEPQIHTFMRISLEAEGFEYLSATSITTALKQYQSHQPHLIVLDLGLPDGDGIELLHGLRQQDKTPVLVLT
ARDQEEEKIRLLEAGANDYLSKPFGIRELIVRIKVLVRDLVDTSSTIDMLQFGPLTLQKSSHQCWLNQQEVALTKKEFAL
LAQLMSHPGQLLKQSDLLRNIWGETHQEDSHYLRILVRQLRKKLNDSDEQQLIKTEPGLGYRLTDLGPP

Sequences:

>Translated_229_residues
MAYKVLVVDDEPQIHTFMRISLEAEGFEYLSATSITTALKQYQSHQPHLIVLDLGLPDGDGIELLHGLRQQDKTPVLVLT
ARDQEEEKIRLLEAGANDYLSKPFGIRELIVRIKVLVRDLVDTSSTIDMLQFGPLTLQKSSHQCWLNQQEVALTKKEFAL
LAQLMSHPGQLLKQSDLLRNIWGETHQEDSHYLRILVRQLRKKLNDSDEQQLIKTEPGLGYRLTDLGPP
>Mature_228_residues
AYKVLVVDDEPQIHTFMRISLEAEGFEYLSATSITTALKQYQSHQPHLIVLDLGLPDGDGIELLHGLRQQDKTPVLVLTA
RDQEEEKIRLLEAGANDYLSKPFGIRELIVRIKVLVRDLVDTSSTIDMLQFGPLTLQKSSHQCWLNQQEVALTKKEFALL
AQLMSHPGQLLKQSDLLRNIWGETHQEDSHYLRILVRQLRKKLNDSDEQQLIKTEPGLGYRLTDLGPP

Specific function: Member of the two-component regulatory system kdpD/kdpE involved in the regulation of the kdp operon [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786911, Length=221, Percent_Identity=43.4389140271493, Blast_Score=180, Evalue=7e-47,
Organism=Escherichia coli, GI1786599, Length=227, Percent_Identity=33.4801762114537, Blast_Score=144, Evalue=4e-36,
Organism=Escherichia coli, GI1790552, Length=222, Percent_Identity=35.5855855855856, Blast_Score=126, Evalue=9e-31,
Organism=Escherichia coli, GI87082012, Length=218, Percent_Identity=32.5688073394495, Blast_Score=126, Evalue=2e-30,
Organism=Escherichia coli, GI1787375, Length=219, Percent_Identity=30.1369863013699, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1789809, Length=226, Percent_Identity=30.9734513274336, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI1786784, Length=223, Percent_Identity=31.390134529148, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1790860, Length=224, Percent_Identity=31.25, Blast_Score=107, Evalue=7e-25,
Organism=Escherichia coli, GI1787229, Length=231, Percent_Identity=29.8701298701299, Blast_Score=104, Evalue=5e-24,
Organism=Escherichia coli, GI1788394, Length=220, Percent_Identity=28.6363636363636, Blast_Score=101, Evalue=3e-23,
Organism=Escherichia coli, GI1790863, Length=228, Percent_Identity=26.7543859649123, Blast_Score=100, Evalue=7e-23,
Organism=Escherichia coli, GI2367329, Length=225, Percent_Identity=32, Blast_Score=98, Evalue=6e-22,
Organism=Escherichia coli, GI1789402, Length=223, Percent_Identity=30.0448430493274, Blast_Score=93, Evalue=1e-20,
Organism=Escherichia coli, GI145693140, Length=228, Percent_Identity=27.6315789473684, Blast_Score=81, Evalue=5e-17,
Organism=Escherichia coli, GI1788550, Length=107, Percent_Identity=33.6448598130841, Blast_Score=74, Evalue=7e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26113; Mature: 25982

Theoretical pI: Translated: 5.85; Mature: 5.85

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAYKVLVVDDEPQIHTFMRISLEAEGFEYLSATSITTALKQYQSHQPHLIVLDLGLPDGD
CCEEEEEECCCCCEEEEEEEEEECCCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCC
GIELLHGLRQQDKTPVLVLTARDQEEEKIRLLEAGANDYLSKPFGIRELIVRIKVLVRDL
HHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHCCCCHHHCCCCCHHHHHHHHHHHHHHH
VDTSSTIDMLQFGPLTLQKSSHQCWLNQQEVALTKKEFALLAQLMSHPGQLLKQSDLLRN
HCCCCHHHHHHCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHH
IWGETHQEDSHYLRILVRQLRKKLNDSDEQQLIKTEPGLGYRLTDLGPP
HHCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCEEECCCCCC
>Mature Secondary Structure 
AYKVLVVDDEPQIHTFMRISLEAEGFEYLSATSITTALKQYQSHQPHLIVLDLGLPDGD
CEEEEEECCCCCEEEEEEEEEECCCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCC
GIELLHGLRQQDKTPVLVLTARDQEEEKIRLLEAGANDYLSKPFGIRELIVRIKVLVRDL
HHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHCCCCHHHCCCCCHHHHHHHHHHHHHHH
VDTSSTIDMLQFGPLTLQKSSHQCWLNQQEVALTKKEFALLAQLMSHPGQLLKQSDLLRN
HCCCCHHHHHHCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHH
IWGETHQEDSHYLRILVRQLRKKLNDSDEQQLIKTEPGLGYRLTDLGPP
HHCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1532388; 8905232; 9278503 [H]