Click here to switch to the map view.

The map label for this gene is hlyU [H]

Identifier: 117918488

GI number: 117918488

Start: 36096

End: 36404

Strand: Reverse

Name: hlyU [H]

Synonym: Shewana3_0029

Alternate gene names: 117918488

Gene position: 36404-36096 (Counterclockwise)

Preceding gene: 117918490

Following gene: 117918483

Centisome position: 0.73

GC content: 45.95

Gene sequence:

>309_bases
ATGCAAAATGATATTGATGTAAATGCAATGGTAACTAATGCGGAAAGTGCGGCTAAATGGCTCAAAGCCATAGCGAATCC
TTATCGCTTAATGATTTTGTGCCTATTGCTGGATAAAGAGCTGAGCGTGACCGAGCTGAATGCAACTGTGCCATTGAGCC
AGTCGGCGCTATCACAGCATTTGGCGGTGTTGCGAGCCGAAGACTTAGTCGATACCCGTAAGAGCTCGCAGATTGTGTAT
TACAAGCTTAAGAATGAGCAAGTCACCCAAGTGATTTCGATTCTCCACAGCCGTTACTGCGCCGTATAA

Upstream 100 bases:

>100_bases
AAATGCAAAAATTGAGATCTGAATTGCCGAGCAGTATGATTGCGTATAGAAATATGTTCAATTAGAATTATCTAATCAAA
AGCGATAAAGTGAGTACCTT

Downstream 100 bases:

>100_bases
ATCGTGTCAGGCGGTAACAATAAAGCCCTAGCAGAGACTAGGGCTTTATCATTTTTATAGCTTGCTAAAGTGTGCCCCAA
AGGCTTCGACTTTACCCCAG

Product: ArsR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 102; Mature: 102

Protein sequence:

>102_residues
MQNDIDVNAMVTNAESAAKWLKAIANPYRLMILCLLLDKELSVTELNATVPLSQSALSQHLAVLRAEDLVDTRKSSQIVY
YKLKNEQVTQVISILHSRYCAV

Sequences:

>Translated_102_residues
MQNDIDVNAMVTNAESAAKWLKAIANPYRLMILCLLLDKELSVTELNATVPLSQSALSQHLAVLRAEDLVDTRKSSQIVY
YKLKNEQVTQVISILHSRYCAV
>Mature_102_residues
MQNDIDVNAMVTNAESAAKWLKAIANPYRLMILCLLLDKELSVTELNATVPLSQSALSQHLAVLRAEDLVDTRKSSQIVY
YKLKNEQVTQVISILHSRYCAV

Specific function: Up-regulates the expression of the hemolysin gene, hlyA, and may promote expression of other virulence determinants in vivo. It may have both positive and negative regulator activities [H]

COG id: COG0640

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH arsR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789021, Length=89, Percent_Identity=44.9438202247191, Blast_Score=76, Evalue=4e-16,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001845
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01022 HTH_5 [H]

EC number: NA

Molecular weight: Translated: 11432; Mature: 11432

Theoretical pI: Translated: 7.41; Mature: 7.41

Prosite motif: PS50987 HTH_ARSR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQNDIDVNAMVTNAESAAKWLKAIANPYRLMILCLLLDKELSVTELNATVPLSQSALSQH
CCCCCCCEEEEECHHHHHHHHHHHCCHHHHHHHHHHHCCCCCEEECCCCCCCCHHHHHHH
LAVLRAEDLVDTRKSSQIVYYKLKNEQVTQVISILHSRYCAV
HHHHHHHHHHHCCCCCEEEEEEECCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MQNDIDVNAMVTNAESAAKWLKAIANPYRLMILCLLLDKELSVTELNATVPLSQSALSQH
CCCCCCCEEEEECHHHHHHHHHHHCCHHHHHHHHHHHCCCCCEEECCCCCCCCHHHHHHH
LAVLRAEDLVDTRKSSQIVYYKLKNEQVTQVISILHSRYCAV
HHHHHHHHHHHCCCCCEEEEEEECCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8231807; 9457888; 10952301 [H]