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The map label for this gene is trkH [H]

Identifier: 117918490

GI number: 117918490

Start: 37204

End: 38646

Strand: Reverse

Name: trkH [H]

Synonym: Shewana3_0031

Alternate gene names: 117918490

Gene position: 38646-37204 (Counterclockwise)

Preceding gene: 117918491

Following gene: 117918488

Centisome position: 0.78

GC content: 51.14

Gene sequence:

>1443_bases
ATGCTGAACTTTAGACCGCTATTGTTTATTTTGGGGCTGTTTCTGTCGATGTTAACAGCCTTTATGTTAGCGCCCCTGCT
CCTTGCCGTGTTCAACGGTGAGGAAACCGTGGGCGCTTTCATGCTGTCGGCTTTAGTCACTGGGATTTGCGCCAGCCTCT
GTTTGCATAACGGCCAGAGCAAAACCATTAACCTCAATATTCGCGATATGTTTCTGCTCACCAGCCTCACTTGGCTGATC
GTGAGCCTGTTTGCCGCCATGCCTTTTACCTTGTACCACGGCATTGGCTATACAGACGCCTTCTTCGAGACCATGTCCGG
CATTACCACCACAGGTTCAACCGTGCTCTCGGGCTTAGATACTATGGACCACAGTATCTTAATCTGGCGCTCGTTGTTGC
AATGGCTCGGCGGTATCGGCTTTATCGTGATGGCGGTAGCGATTCTGCCCTTCTTAAACGTCGGCGGTATGCGGCTGTTC
CGCACCGAGTCATCGGATTGGAGCGATAAGGCGGTGCCACGCACCCAAAACATGGCTAAGCATCTCTTTTTTATCTATAT
CTTGCTGACCGTGATGTGCTGTGTTGCCTACCATCTTGCAGGCATGACTTGGTTTCAAGCCATTAACCATGCGATGACCA
CACTGTCGACGGGCGGCTATTCGACCTCAGATAACTCGATGGCGGCGTTTTCGAATTCGGCCCATTGGGTTGGCGTTGTG
TTTATGGCGGCGGGAGGCTTACCCCTGCTGATGTTTGTGCAGATGATCCAGCAGCGAGACTTTACCGTCTGGAACGATGC
TCAAGTCAAAGGCTTCTTGTTTTTCCTCACTTTTGTGTCTTGTTTTATTGGCTTCTGGCTGTGGCAAACGCGGGATATCG
CCCTTATCGACGCACTGCGCCTCTCCAGCTTTAACGTGGTTTCCGTGGTCACCACCACAGGTTATGGTTTAACTGACTAC
GGCGCCTGGGGCGCGTTTGCGAATATCGCGTTTTTATTCTTAATGTTTGTCGGCAGCTGCTCGGGCTCAACCTCTGGCGG
GATTAAAATCTTCCGCTTCCAAATTGCCGGCGCCATTATGCGCGAGCAGTTAAAGCAGCAATGCCATCCCAATGGCATCT
TCCGGGAGCGCTATAACAACCGTTTGATCAGTGAAGATATTGTGCGTTCACTGATCACCTTTGTGCTGCTCTTTATGTTT
GTGATTGTTGGACTTTCGGTGATTCTGGTGCTGACTGGGCTAGACCCCATGACCAGCTTTACCGGCGCTATTACCGCAGT
TACCAACGTTGGCCCAGGGCTTGGCCCCATTATTGGCACAGCGGGTAATTTCTCGACGCTGCCCGATTTGGCTAAATGGG
CGCTTTCTTTGGGTATGTTGCTCGGCCGCTTAGAGATTTTAACCGTAGCTGTACTGTTCCATCCCAGCTTTTGGAAATAC
TAA

Upstream 100 bases:

>100_bases
AAGGGGATCACGTGATTCTGTTCCTCGTGAACAAAAAGTTTGTCGGCGAAGTCGAGAAACTGTTCCAACCTAGCGCCTTC
TTCTTCTAAGTCATCATCTT

Downstream 100 bases:

>100_bases
TCGTATAAATCAAAAACTAAAAATGCGCTCAGTGAGCGCATTTTTATTAGGCGGGTTCAGTAACCTCGACCAAGGTTAGC
AGATGGTCGGCATAGACCTT

Product: TrkH family potassium uptake protein

Products: Proton [Cytoplasm]; K (I) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 480; Mature: 480

Protein sequence:

>480_residues
MLNFRPLLFILGLFLSMLTAFMLAPLLLAVFNGEETVGAFMLSALVTGICASLCLHNGQSKTINLNIRDMFLLTSLTWLI
VSLFAAMPFTLYHGIGYTDAFFETMSGITTTGSTVLSGLDTMDHSILIWRSLLQWLGGIGFIVMAVAILPFLNVGGMRLF
RTESSDWSDKAVPRTQNMAKHLFFIYILLTVMCCVAYHLAGMTWFQAINHAMTTLSTGGYSTSDNSMAAFSNSAHWVGVV
FMAAGGLPLLMFVQMIQQRDFTVWNDAQVKGFLFFLTFVSCFIGFWLWQTRDIALIDALRLSSFNVVSVVTTTGYGLTDY
GAWGAFANIAFLFLMFVGSCSGSTSGGIKIFRFQIAGAIMREQLKQQCHPNGIFRERYNNRLISEDIVRSLITFVLLFMF
VIVGLSVILVLTGLDPMTSFTGAITAVTNVGPGLGPIIGTAGNFSTLPDLAKWALSLGMLLGRLEILTVAVLFHPSFWKY

Sequences:

>Translated_480_residues
MLNFRPLLFILGLFLSMLTAFMLAPLLLAVFNGEETVGAFMLSALVTGICASLCLHNGQSKTINLNIRDMFLLTSLTWLI
VSLFAAMPFTLYHGIGYTDAFFETMSGITTTGSTVLSGLDTMDHSILIWRSLLQWLGGIGFIVMAVAILPFLNVGGMRLF
RTESSDWSDKAVPRTQNMAKHLFFIYILLTVMCCVAYHLAGMTWFQAINHAMTTLSTGGYSTSDNSMAAFSNSAHWVGVV
FMAAGGLPLLMFVQMIQQRDFTVWNDAQVKGFLFFLTFVSCFIGFWLWQTRDIALIDALRLSSFNVVSVVTTTGYGLTDY
GAWGAFANIAFLFLMFVGSCSGSTSGGIKIFRFQIAGAIMREQLKQQCHPNGIFRERYNNRLISEDIVRSLITFVLLFMF
VIVGLSVILVLTGLDPMTSFTGAITAVTNVGPGLGPIIGTAGNFSTLPDLAKWALSLGMLLGRLEILTVAVLFHPSFWKY
>Mature_480_residues
MLNFRPLLFILGLFLSMLTAFMLAPLLLAVFNGEETVGAFMLSALVTGICASLCLHNGQSKTINLNIRDMFLLTSLTWLI
VSLFAAMPFTLYHGIGYTDAFFETMSGITTTGSTVLSGLDTMDHSILIWRSLLQWLGGIGFIVMAVAILPFLNVGGMRLF
RTESSDWSDKAVPRTQNMAKHLFFIYILLTVMCCVAYHLAGMTWFQAINHAMTTLSTGGYSTSDNSMAAFSNSAHWVGVV
FMAAGGLPLLMFVQMIQQRDFTVWNDAQVKGFLFFLTFVSCFIGFWLWQTRDIALIDALRLSSFNVVSVVTTTGYGLTDY
GAWGAFANIAFLFLMFVGSCSGSTSGGIKIFRFQIAGAIMREQLKQQCHPNGIFRERYNNRLISEDIVRSLITFVLLFMF
VIVGLSVILVLTGLDPMTSFTGAITAVTNVGPGLGPIIGTAGNFSTLPDLAKWALSLGMLLGRLEILTVAVLFHPSFWKY

Specific function: Low-affinity potassium transport system. Interacts with trk system potassium uptake protein trkA and requires trkE for transport activity [H]

COG id: COG0168

COG function: function code P; Trk-type K+ transport systems, membrane components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trkH potassium transport family [H]

Homologues:

Organism=Escherichia coli, GI48994987, Length=486, Percent_Identity=34.7736625514403, Blast_Score=241, Evalue=8e-65,
Organism=Escherichia coli, GI1787626, Length=475, Percent_Identity=31.7894736842105, Blast_Score=229, Evalue=4e-61,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003445
- InterPro:   IPR004772 [H]

Pfam domain/function: PF02386 TrkH [H]

EC number: NA

Molecular weight: Translated: 52820; Mature: 52820

Theoretical pI: Translated: 7.82; Mature: 7.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNFRPLLFILGLFLSMLTAFMLAPLLLAVFNGEETVGAFMLSALVTGICASLCLHNGQS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCC
KTINLNIRDMFLLTSLTWLIVSLFAAMPFTLYHGIGYTDAFFETMSGITTTGSTVLSGLD
CEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHH
TMDHSILIWRSLLQWLGGIGFIVMAVAILPFLNVGGMRLFRTESSDWSDKAVPRTQNMAK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCHHHHHH
HLFFIYILLTVMCCVAYHLAGMTWFQAINHAMTTLSTGGYSTSDNSMAAFSNSAHWVGVV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCCCHHHHHH
FMAAGGLPLLMFVQMIQQRDFTVWNDAQVKGFLFFLTFVSCFIGFWLWQTRDIALIDALR
HHHCCCCHHHHHHHHHHHCCCCEECCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
LSSFNVVSVVTTTGYGLTDYGAWGAFANIAFLFLMFVGSCSGSTSGGIKIFRFQIAGAIM
HCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEHHHHHHHHH
REQLKQQCHPNGIFRERYNNRLISEDIVRSLITFVLLFMFVIVGLSVILVLTGLDPMTSF
HHHHHHHCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
TGAITAVTNVGPGLGPIIGTAGNFSTLPDLAKWALSLGMLLGRLEILTVAVLFHPSFWKY
HHHHHHHHHCCCCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCC
>Mature Secondary Structure
MLNFRPLLFILGLFLSMLTAFMLAPLLLAVFNGEETVGAFMLSALVTGICASLCLHNGQS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCC
KTINLNIRDMFLLTSLTWLIVSLFAAMPFTLYHGIGYTDAFFETMSGITTTGSTVLSGLD
CEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHH
TMDHSILIWRSLLQWLGGIGFIVMAVAILPFLNVGGMRLFRTESSDWSDKAVPRTQNMAK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCHHHHHH
HLFFIYILLTVMCCVAYHLAGMTWFQAINHAMTTLSTGGYSTSDNSMAAFSNSAHWVGVV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCCCHHHHHH
FMAAGGLPLLMFVQMIQQRDFTVWNDAQVKGFLFFLTFVSCFIGFWLWQTRDIALIDALR
HHHCCCCHHHHHHHHHHHCCCCEECCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
LSSFNVVSVVTTTGYGLTDYGAWGAFANIAFLFLMFVGSCSGSTSGGIKIFRFQIAGAIM
HCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEHHHHHHHHH
REQLKQQCHPNGIFRERYNNRLISEDIVRSLITFVLLFMFVIVGLSVILVLTGLDPMTSF
HHHHHHHCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
TGAITAVTNVGPGLGPIIGTAGNFSTLPDLAKWALSLGMLLGRLEILTVAVLFHPSFWKY
HHHHHHHHHCCCCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; K (I) [Periplasm] [C]

Specific reaction: Proton [Periplasm] + K (I) [Periplasm] = Proton [Cytoplasm] + K (I) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]