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The map label for this gene is dtpA [H]

Identifier: 117918463

GI number: 117918463

Start: 3725

End: 5272

Strand: Direct

Name: dtpA [H]

Synonym: Shewana3_0004

Alternate gene names: 117918463

Gene position: 3725-5272 (Clockwise)

Preceding gene: NA

Following gene: 117918468

Centisome position: 0.07

GC content: 47.42

Gene sequence:

>1548_bases
ATGACTACTCCTGCCGATGCGCCAAAGTGGCCACGCCAAATACCCTATATTATTGCCAGTGAAGCGTGTGAGCGTTTCAG
TTTTTATGGCATGCGCAACATTCTAACACCATTCTTGATGACGGCACTTTTGCTCTCTATTCCCGAAGATCTTCGCGGAG
CGGTGGCAAAGGATGTGTTCCATTCGTTCGTCATTGGGGTGTATTTTTTCCCCTTACTCGGTGGTTGGATTGCAGATAGA
TTCTTTGGTAAGTACAACACTATTCTGTGGTTAAGCTTACTTTACTGTGTGGGCCATGCGTTTTTGGCAATTTTTGAGCA
CAGTGTGCAAGGCTTTTACACCGGCTTATTTTTAATTGCCTTAGGTTCAGGCGGGATTAAACCTTTAGTTTCTTCGTTTA
TGGGCGATCAGTTTGATCAGAGTAACAAGTCTTTGGCGCAAAAGGCCTTCGATATGTTCTATTTTACGATCAACTTTGGG
TCCTTCTTCGCATCCTTATCTATGCCATTGTTACTCAAGAATTTTGGCGCAGCTGTGGCTTTCGGGATCCCCGGTGTGTT
GATGTTTATCGCCACGGTATTTTTCTGGTTAGGCCGCAAACGTTATGTGCATATGCCGCCAGAACCAAAGGATCCCCATG
GATTTTTACCTGTGATCCGCAGCGCCTTGCTTACTAAGGCCGAAGGCAAAGCCAATATCGGTTTAGTGTTAGCCCTAATT
GGTGGTGTTTCAGCCGCTTATGCGCTGGTGAATATTCCGACCCTAGGGATTGTGGCTGGTTTGTGTAGCGCTATGGTGCT
GCTGATGGGATTTGTTGGTTTTGGGGCGTCATTGCAGCTTGAGCGCGCTAGGGGAGTTCACCCTGATGCGGCCGTGGATG
GCGTACGTTCAGTGCTACGTATTTTGGTGTTGTTCGCCTTAGTCACGCCATTTTGGTCCTTATTCGATCAAAAGGCGTCG
ACTTGGATTTTGCAGGCTAACGATATGGTTAAACCTTCGTGGTTTGAACCTGCGATGATGCAGGCATTAAACCCGCTGTT
AGTGATGCTGTTGATTCCATTCAATAACTTCGTGTTATATCCTGCTATTGAGCGTATGGGCGTGAAATTAACTGCGCTGC
GTAAAATGGGCGCGGGGATCGCGATAACTGGCTTAAGCTGGATTGTGGTTGGGACGATTCAGTTGATGATGGACGGTGGC
TCGGCGCTGTCTATCTTCTGGCAGATTTTACCCTACGCCTTACTGACTTTTGGTGAAGTATTAGTTTCGGCAACGGGTTT
AGAATTTGCCTACAGCCAAGCACCTAAGGCTATGAAAGGCACTATTATGAGTTTTTGGACCTTATCGGTGACCGTCGGTA
ACCTTTGGGTATTACTCGCCAATGTGAGCGTAAAAAGCCCTGCGGTGACGGAACAAATTGTTCAAACCGGGATGAGTGTG
ACGGCATTCCAAATGTTCTTCTTTGCGGGATTTGCGATCTTGGCGGCTGCCATCTTCGCGCTCTATGCTCGGTCCTATCA
AATGCAGGACCATTATCGCCAAGTTTAG

Upstream 100 bases:

>100_bases
TTACTCACTATTGATTTGCAGTCTGCTAGTATCTTTGGCTGCAATCGAGGTTTTATACCTATGACTGTAAATTTTTATAA
CAATTATAATAGGATAACAG

Downstream 100 bases:

>100_bases
ATAAACTATTTAAGACAAAGCGCCTTTAAATAAAAAATCAGCCCCTAAGCGAACTTAGTGGGCTGATTTTTTATTGCTCG
TTTAGCTAAACGCTAAAGCG

Product: TGF-beta receptor, type I/II extracellular region

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 515; Mature: 514

Protein sequence:

>515_residues
MTTPADAPKWPRQIPYIIASEACERFSFYGMRNILTPFLMTALLLSIPEDLRGAVAKDVFHSFVIGVYFFPLLGGWIADR
FFGKYNTILWLSLLYCVGHAFLAIFEHSVQGFYTGLFLIALGSGGIKPLVSSFMGDQFDQSNKSLAQKAFDMFYFTINFG
SFFASLSMPLLLKNFGAAVAFGIPGVLMFIATVFFWLGRKRYVHMPPEPKDPHGFLPVIRSALLTKAEGKANIGLVLALI
GGVSAAYALVNIPTLGIVAGLCSAMVLLMGFVGFGASLQLERARGVHPDAAVDGVRSVLRILVLFALVTPFWSLFDQKAS
TWILQANDMVKPSWFEPAMMQALNPLLVMLLIPFNNFVLYPAIERMGVKLTALRKMGAGIAITGLSWIVVGTIQLMMDGG
SALSIFWQILPYALLTFGEVLVSATGLEFAYSQAPKAMKGTIMSFWTLSVTVGNLWVLLANVSVKSPAVTEQIVQTGMSV
TAFQMFFFAGFAILAAAIFALYARSYQMQDHYRQV

Sequences:

>Translated_515_residues
MTTPADAPKWPRQIPYIIASEACERFSFYGMRNILTPFLMTALLLSIPEDLRGAVAKDVFHSFVIGVYFFPLLGGWIADR
FFGKYNTILWLSLLYCVGHAFLAIFEHSVQGFYTGLFLIALGSGGIKPLVSSFMGDQFDQSNKSLAQKAFDMFYFTINFG
SFFASLSMPLLLKNFGAAVAFGIPGVLMFIATVFFWLGRKRYVHMPPEPKDPHGFLPVIRSALLTKAEGKANIGLVLALI
GGVSAAYALVNIPTLGIVAGLCSAMVLLMGFVGFGASLQLERARGVHPDAAVDGVRSVLRILVLFALVTPFWSLFDQKAS
TWILQANDMVKPSWFEPAMMQALNPLLVMLLIPFNNFVLYPAIERMGVKLTALRKMGAGIAITGLSWIVVGTIQLMMDGG
SALSIFWQILPYALLTFGEVLVSATGLEFAYSQAPKAMKGTIMSFWTLSVTVGNLWVLLANVSVKSPAVTEQIVQTGMSV
TAFQMFFFAGFAILAAAIFALYARSYQMQDHYRQV
>Mature_514_residues
TTPADAPKWPRQIPYIIASEACERFSFYGMRNILTPFLMTALLLSIPEDLRGAVAKDVFHSFVIGVYFFPLLGGWIADRF
FGKYNTILWLSLLYCVGHAFLAIFEHSVQGFYTGLFLIALGSGGIKPLVSSFMGDQFDQSNKSLAQKAFDMFYFTINFGS
FFASLSMPLLLKNFGAAVAFGIPGVLMFIATVFFWLGRKRYVHMPPEPKDPHGFLPVIRSALLTKAEGKANIGLVLALIG
GVSAAYALVNIPTLGIVAGLCSAMVLLMGFVGFGASLQLERARGVHPDAAVDGVRSVLRILVLFALVTPFWSLFDQKAST
WILQANDMVKPSWFEPAMMQALNPLLVMLLIPFNNFVLYPAIERMGVKLTALRKMGAGIAITGLSWIVVGTIQLMMDGGS
ALSIFWQILPYALLTFGEVLVSATGLEFAYSQAPKAMKGTIMSFWTLSVTVGNLWVLLANVSVKSPAVTEQIVQTGMSVT
AFQMFFFAGFAILAAAIFALYARSYQMQDHYRQV

Specific function: Proton-dependent permease that transports di- and tripeptides [H]

COG id: COG3104

COG function: function code E; Dipeptide/tripeptide permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PTR2/POT transporter (TC 2.A.17) family. DtpA subfamily [H]

Homologues:

Organism=Homo sapiens, GI226371746, Length=390, Percent_Identity=32.8205128205128, Blast_Score=194, Evalue=1e-49,
Organism=Homo sapiens, GI4827008, Length=419, Percent_Identity=30.0715990453461, Blast_Score=180, Evalue=2e-45,
Organism=Homo sapiens, GI226371748, Length=381, Percent_Identity=31.758530183727, Blast_Score=174, Evalue=2e-43,
Organism=Homo sapiens, GI21717816, Length=557, Percent_Identity=22.4416517055655, Blast_Score=115, Evalue=1e-25,
Organism=Escherichia coli, GI1787922, Length=454, Percent_Identity=25.9911894273128, Blast_Score=119, Evalue=5e-28,
Organism=Escherichia coli, GI1790572, Length=195, Percent_Identity=32.8205128205128, Blast_Score=99, Evalue=9e-22,
Organism=Escherichia coli, GI1786927, Length=421, Percent_Identity=24.4655581947743, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1789911, Length=453, Percent_Identity=24.0618101545254, Blast_Score=84, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17569141, Length=503, Percent_Identity=32.20675944334, Blast_Score=196, Evalue=2e-50,
Organism=Caenorhabditis elegans, GI71987453, Length=412, Percent_Identity=31.7961165048544, Blast_Score=182, Evalue=3e-46,
Organism=Caenorhabditis elegans, GI17541704, Length=410, Percent_Identity=32.6829268292683, Blast_Score=179, Evalue=2e-45,
Organism=Saccharomyces cerevisiae, GI6322946, Length=552, Percent_Identity=24.6376811594203, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI28571098, Length=455, Percent_Identity=31.6483516483516, Blast_Score=188, Evalue=1e-47,
Organism=Drosophila melanogaster, GI28571102, Length=422, Percent_Identity=32.2274881516588, Blast_Score=187, Evalue=2e-47,
Organism=Drosophila melanogaster, GI28571100, Length=422, Percent_Identity=32.2274881516588, Blast_Score=187, Evalue=2e-47,
Organism=Drosophila melanogaster, GI24639585, Length=377, Percent_Identity=33.42175066313, Blast_Score=174, Evalue=1e-43,
Organism=Drosophila melanogaster, GI24639583, Length=377, Percent_Identity=33.42175066313, Blast_Score=174, Evalue=1e-43,
Organism=Drosophila melanogaster, GI24639581, Length=377, Percent_Identity=33.42175066313, Blast_Score=174, Evalue=1e-43,
Organism=Drosophila melanogaster, GI24645459, Length=527, Percent_Identity=23.719165085389, Blast_Score=96, Evalue=7e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016196
- InterPro:   IPR000109
- InterPro:   IPR005279
- InterPro:   IPR018456 [H]

Pfam domain/function: PF00854 PTR2 [H]

EC number: NA

Molecular weight: Translated: 56493; Mature: 56361

Theoretical pI: Translated: 9.56; Mature: 9.56

Prosite motif: PS01022 PTR2_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTPADAPKWPRQIPYIIASEACERFSFYGMRNILTPFLMTALLLSIPEDLRGAVAKDVF
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
HSFVIGVYFFPLLGGWIADRFFGKYNTILWLSLLYCVGHAFLAIFEHSVQGFYTGLFLIA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGSGGIKPLVSSFMGDQFDQSNKSLAQKAFDMFYFTINFGSFFASLSMPLLLKNFGAAVA
CCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHEEEEHHHHHHHHHHHHHHHHHCHHHH
FGIPGVLMFIATVFFWLGRKRYVHMPPEPKDPHGFLPVIRSALLTKAEGKANIGLVLALI
HHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHH
GGVSAAYALVNIPTLGIVAGLCSAMVLLMGFVGFGASLQLERARGVHPDAAVDGVRSVLR
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHCCCCCHHHHHHHHHHHH
ILVLFALVTPFWSLFDQKASTWILQANDMVKPSWFEPAMMQALNPLLVMLLIPFNNFVLY
HHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEE
PAIERMGVKLTALRKMGAGIAITGLSWIVVGTIQLMMDGGSALSIFWQILPYALLTFGEV
ECHHHHCCHHHHHHHHCCCEEEHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
LVSATGLEFAYSQAPKAMKGTIMSFWTLSVTVGNLWVLLANVSVKSPAVTEQIVQTGMSV
HHHHCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCHHHHHHHHCCCHH
TAFQMFFFAGFAILAAAIFALYARSYQMQDHYRQV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TTPADAPKWPRQIPYIIASEACERFSFYGMRNILTPFLMTALLLSIPEDLRGAVAKDVF
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH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HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA