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The map label for this gene is dnaA [H]

Identifier: 117918468

GI number: 117918468

Start: 9651

End: 11033

Strand: Direct

Name: dnaA [H]

Synonym: Shewana3_0009

Alternate gene names: 117918468

Gene position: 9651-11033 (Clockwise)

Preceding gene: 117918463

Following gene: 117918469

Centisome position: 0.19

GC content: 46.35

Gene sequence:

>1383_bases
GTGGCGGTTTCACTTTGGCAACAATGTATCGGAAGACTGCAAGACGAGCTTTCTGCTCAGCAGTTCAGTATGTGGATCAG
ACCGTTACAAGCCGAAATGGATGGAGATACTTTGGTGCTTTATGCGCCTAACCGCTTCGTGCTCGATTGGGTTAGGGATA
AGTACATCAATATCATTAATCAGTTTTTTACTGAGCAAATGGGTAATGATGCACCTAAGTTACGCTTCGATATCGGTAGC
CGTCCGTCAGCGAAAAAGCCTGAGCCAGCTCCAGTTGCGGCTGTGCGTGTGCCTAATCCCCAAACTAAAGCTTCAGTAGG
GACTTCATTTAATACCACTGAGCCTGTTGCTAACGCTAATCATCGCAGCAATATCAATCCCACTTACCAATTCGACAACT
TCGTTGAGGGTAAGTCTAACCAACTCGGTAAAGCGGCCGCTCTGCAGGTTGCTGAAAATCCGGGTGGTGCCTATAACCCG
CTGTTCCTTTATGGTGGTACGGGTTTAGGTAAGACCCACTTATTACATGCAGTCGGTAACGGCATCATCAAAAATAATCC
CGATGCGAAAGTTGTGTACATGCACTCCGAGCGTTTTGTGCAAGACATGGTGAAAGCGCTACAAAACAATGCGATCGAAG
AGTTCAAACGTTACTACCGCAGTGTCGATGCCCTGTTTATCGACGATATTCAATTCTTCGCCAATAAAGACAGATCGCAG
GAAGAATTTTTCCATACCTTTAACGCGTTGCTTGAAGGTAATCATCAGATCATCCTGACATCGGATCGTTATCCTAAAGA
GATCGACGGGGTAGAGGACAGATTAAAATCTCGCTTTGGTTGGGGCTTAACGGTTGCGATTGAACCGCCAGAGCTTGAAA
CCCGTGTGGCGATTTTGATGCGTAAAGCCCAAGAGAGCGGTATCAATCTTCCCGACGAAGTCGCCTTCTTTATTGCTAAG
CGCTTACGTTCGAACGTTCGCGAGTTAGAAGGGGCGTTAAACCGCGTTATCGCGAACGCTAACTTTACTGGCCGCCCAAT
TACAATTGATTTTGTGCGTGAAGCCCTGCGTGACCTCTTGGCACTGCAGGAAAAATTAGTCACTATAGACAACATTCAGA
AAACCGTAGCTGAATACTACAAAATCAAGATGGCTGATATGTTGTCTAAGCGTCGTTCGCGCAGTGTTGCGCGCCCTAGA
CAAGTGGCCATGGCGTTATCCAAAGAATTAACTAACCAGAGCTTGCCGGAAATTGGTGATGCCTTTGGTGGTCGAGATCA
CACCACAGTGTTACATGCCTGTCGTAAGATTGCTCAGCTACGGGAAGAGAGTCACGACATTAAAGAAGATTATGCTAACT
TGATTAGAACCTTATCTTCTTAA

Upstream 100 bases:

>100_bases
AGAATGATCTTGTTGGGGATAATTATTTTTTAAGGATAGCGATCATTGAGATCTCGCTATAGAATACACCTCTTTTTGAT
GATCTTTTGGGGATAACTTA

Downstream 100 bases:

>100_bases
AATCAAGGAATTTGGACACTATGAAATTTTCAATTGATAGGGACGCCCTATTAAAGCCGCTTCAATTGGTTTGTGGTGCG
GTAGAAAGACGCCATAACTT

Product: chromosomal replication initiation protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 460; Mature: 459

Protein sequence:

>460_residues
MAVSLWQQCIGRLQDELSAQQFSMWIRPLQAEMDGDTLVLYAPNRFVLDWVRDKYINIINQFFTEQMGNDAPKLRFDIGS
RPSAKKPEPAPVAAVRVPNPQTKASVGTSFNTTEPVANANHRSNINPTYQFDNFVEGKSNQLGKAAALQVAENPGGAYNP
LFLYGGTGLGKTHLLHAVGNGIIKNNPDAKVVYMHSERFVQDMVKALQNNAIEEFKRYYRSVDALFIDDIQFFANKDRSQ
EEFFHTFNALLEGNHQIILTSDRYPKEIDGVEDRLKSRFGWGLTVAIEPPELETRVAILMRKAQESGINLPDEVAFFIAK
RLRSNVRELEGALNRVIANANFTGRPITIDFVREALRDLLALQEKLVTIDNIQKTVAEYYKIKMADMLSKRRSRSVARPR
QVAMALSKELTNQSLPEIGDAFGGRDHTTVLHACRKIAQLREESHDIKEDYANLIRTLSS

Sequences:

>Translated_460_residues
MAVSLWQQCIGRLQDELSAQQFSMWIRPLQAEMDGDTLVLYAPNRFVLDWVRDKYINIINQFFTEQMGNDAPKLRFDIGS
RPSAKKPEPAPVAAVRVPNPQTKASVGTSFNTTEPVANANHRSNINPTYQFDNFVEGKSNQLGKAAALQVAENPGGAYNP
LFLYGGTGLGKTHLLHAVGNGIIKNNPDAKVVYMHSERFVQDMVKALQNNAIEEFKRYYRSVDALFIDDIQFFANKDRSQ
EEFFHTFNALLEGNHQIILTSDRYPKEIDGVEDRLKSRFGWGLTVAIEPPELETRVAILMRKAQESGINLPDEVAFFIAK
RLRSNVRELEGALNRVIANANFTGRPITIDFVREALRDLLALQEKLVTIDNIQKTVAEYYKIKMADMLSKRRSRSVARPR
QVAMALSKELTNQSLPEIGDAFGGRDHTTVLHACRKIAQLREESHDIKEDYANLIRTLSS
>Mature_459_residues
AVSLWQQCIGRLQDELSAQQFSMWIRPLQAEMDGDTLVLYAPNRFVLDWVRDKYINIINQFFTEQMGNDAPKLRFDIGSR
PSAKKPEPAPVAAVRVPNPQTKASVGTSFNTTEPVANANHRSNINPTYQFDNFVEGKSNQLGKAAALQVAENPGGAYNPL
FLYGGTGLGKTHLLHAVGNGIIKNNPDAKVVYMHSERFVQDMVKALQNNAIEEFKRYYRSVDALFIDDIQFFANKDRSQE
EFFHTFNALLEGNHQIILTSDRYPKEIDGVEDRLKSRFGWGLTVAIEPPELETRVAILMRKAQESGINLPDEVAFFIAKR
LRSNVRELEGALNRVIANANFTGRPITIDFVREALRDLLALQEKLVTIDNIQKTVAEYYKIKMADMLSKRRSRSVARPRQ
VAMALSKELTNQSLPEIGDAFGGRDHTTVLHACRKIAQLREESHDIKEDYANLIRTLSS

Specific function: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box):5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phosph

COG id: COG0593

COG function: function code L; ATPase involved in DNA replication initiation

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dnaA family [H]

Homologues:

Organism=Escherichia coli, GI2367267, Length=467, Percent_Identity=79.4432548179872, Blast_Score=763, Evalue=0.0,
Organism=Escherichia coli, GI226510964, Length=231, Percent_Identity=27.2727272727273, Blast_Score=79, Evalue=8e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR001957
- InterPro:   IPR020591
- InterPro:   IPR018312
- InterPro:   IPR013159
- InterPro:   IPR013317
- InterPro:   IPR010921 [H]

Pfam domain/function: PF00308 Bac_DnaA; PF08299 Bac_DnaA_C [H]

EC number: NA

Molecular weight: Translated: 51985; Mature: 51854

Theoretical pI: Translated: 8.58; Mature: 8.58

Prosite motif: PS01008 DNAA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVSLWQQCIGRLQDELSAQQFSMWIRPLQAEMDGDTLVLYAPNRFVLDWVRDKYINIIN
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHH
QFFTEQMGNDAPKLRFDIGSRPSAKKPEPAPVAAVRVPNPQTKASVGTSFNTTEPVANAN
HHHHHHHCCCCCEEEEECCCCCCCCCCCCCCEEEEECCCCCCHHHCCCCCCCCCCCCCCC
HRSNINPTYQFDNFVEGKSNQLGKAAALQVAENPGGAYNPLFLYGGTGLGKTHLLHAVGN
CCCCCCCCCCCCCCCCCCCCCCCHHHHHEEECCCCCCCCCEEEECCCCCCHHHHHHHHCC
GIIKNNPDAKVVYMHSERFVQDMVKALQNNAIEEFKRYYRSVDALFIDDIQFFANKDRSQ
CCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
EEFFHTFNALLEGNHQIILTSDRYPKEIDGVEDRLKSRFGWGLTVAIEPPELETRVAILM
HHHHHHHHHHHCCCCEEEEECCCCCCHHCCHHHHHHHHCCCCEEEEECCCCHHHHHHHHH
RKAQESGINLPDEVAFFIAKRLRSNVRELEGALNRVIANANFTGRPITIDFVREALRDLL
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEHHHHHHHHHHHH
ALQEKLVTIDNIQKTVAEYYKIKMADMLSKRRSRSVARPRQVAMALSKELTNQSLPEIGD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCHHHHH
AFGGRDHTTVLHACRKIAQLREESHDIKEDYANLIRTLSS
HCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AVSLWQQCIGRLQDELSAQQFSMWIRPLQAEMDGDTLVLYAPNRFVLDWVRDKYINIIN
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHH
QFFTEQMGNDAPKLRFDIGSRPSAKKPEPAPVAAVRVPNPQTKASVGTSFNTTEPVANAN
HHHHHHHCCCCCEEEEECCCCCCCCCCCCCCEEEEECCCCCCHHHCCCCCCCCCCCCCCC
HRSNINPTYQFDNFVEGKSNQLGKAAALQVAENPGGAYNPLFLYGGTGLGKTHLLHAVGN
CCCCCCCCCCCCCCCCCCCCCCCHHHHHEEECCCCCCCCCEEEECCCCCCHHHHHHHHCC
GIIKNNPDAKVVYMHSERFVQDMVKALQNNAIEEFKRYYRSVDALFIDDIQFFANKDRSQ
CCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
EEFFHTFNALLEGNHQIILTSDRYPKEIDGVEDRLKSRFGWGLTVAIEPPELETRVAILM
HHHHHHHHHHHCCCCEEEEECCCCCCHHCCHHHHHHHHCCCCEEEEECCCCHHHHHHHHH
RKAQESGINLPDEVAFFIAKRLRSNVRELEGALNRVIANANFTGRPITIDFVREALRDLL
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEHHHHHHHHHHHH
ALQEKLVTIDNIQKTVAEYYKIKMADMLSKRRSRSVARPRQVAMALSKELTNQSLPEIGD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCHHHHH
AFGGRDHTTVLHACRKIAQLREESHDIKEDYANLIRTLSS
HCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA