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The map label for this gene is umuC [H]

Identifier: 117676286

GI number: 117676286

Start: 233152

End: 233817

Strand: Direct

Name: umuC [H]

Synonym: Shewana3_4349

Alternate gene names: 117676286

Gene position: 233152-233817 (Clockwise)

Preceding gene: 117676285

Following gene: 117676293

Centisome position: 83.58

GC content: 45.65

Gene sequence:

>666_bases
ATGAATATTAAAACGGCCTACGACCTAGCACAAATGCCTGCAGGGCATGCTCGTAAGCAATTTAGCATTGAAATCGAGCG
TACGGTTCGTGAGCTAAATGGCATCGAGTGCAAACAATGGGATCAGGCAAGAGCCGATAAACAGCAGATATTTTCAACTC
GTTCAGTTGGTGAGCGGATAACCGATTTTAACTCTTTACTGCAGGCATTGAGTAAGCATGTTGGAATTGCAGCAGCGAAG
GCAAGGGCACAGGGATCTAGTTGCAAATCAATGCTACTGTTCGCCAGTAATTCGCCTTTTGATGATCAACCTAAAAGCTT
TAAAACGCTGATCCATTTCCCATGTGCGACAAATAGCACGGTCGAAATGACGCAGGCTGTCTCAGCGGCTGCACCCAAAT
TATTCAGAGAAGGTGTACGTTACTACAAAATCGGAGTTGGGCTCATCAACCTCGTTTGTGACAAGCGTCAGCAATTCGAC
TTATTTAATGCGCCAAAAGCTAATCCTGCTTTGATGCAAGCGCTTGATGGCATTAACTTTAGGTATGGCCGTGATACGCT
GTTCTTAGCTGCACAGGGAATCGAACAAAAGTGGGCTATGCGGCGAGAACTGCTTAGCCCTCAGTACACAACCAAGTGGG
ACTGTTTGCCTATGATAAAATGCTAA

Upstream 100 bases:

>100_bases
CGCCTGCAACCTCTAGGGCCTCAACCTGACAGGCCGCACGCTTAGCGTACGATTTTGTCCGTTTTCTCTATCGTCCCCTA
TTAGTAAAAAACTAGAGTTG

Downstream 100 bases:

>100_bases
TTTTGACCCTTTTCAATTTATCTGTGGCCGAAGTTGTAATGTTCGGTCCTGTTGGGTTGACCATATTTTGGTATTGCTCC
ACATTGTATTCAGGATCATT

Product: umuC protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 221; Mature: 221

Protein sequence:

>221_residues
MNIKTAYDLAQMPAGHARKQFSIEIERTVRELNGIECKQWDQARADKQQIFSTRSVGERITDFNSLLQALSKHVGIAAAK
ARAQGSSCKSMLLFASNSPFDDQPKSFKTLIHFPCATNSTVEMTQAVSAAAPKLFREGVRYYKIGVGLINLVCDKRQQFD
LFNAPKANPALMQALDGINFRYGRDTLFLAAQGIEQKWAMRRELLSPQYTTKWDCLPMIKC

Sequences:

>Translated_221_residues
MNIKTAYDLAQMPAGHARKQFSIEIERTVRELNGIECKQWDQARADKQQIFSTRSVGERITDFNSLLQALSKHVGIAAAK
ARAQGSSCKSMLLFASNSPFDDQPKSFKTLIHFPCATNSTVEMTQAVSAAAPKLFREGVRYYKIGVGLINLVCDKRQQFD
LFNAPKANPALMQALDGINFRYGRDTLFLAAQGIEQKWAMRRELLSPQYTTKWDCLPMIKC
>Mature_221_residues
MNIKTAYDLAQMPAGHARKQFSIEIERTVRELNGIECKQWDQARADKQQIFSTRSVGERITDFNSLLQALSKHVGIAAAK
ARAQGSSCKSMLLFASNSPFDDQPKSFKTLIHFPCATNSTVEMTQAVSAAAPKLFREGVRYYKIGVGLINLVCDKRQQFD
LFNAPKANPALMQALDGINFRYGRDTLFLAAQGIEQKWAMRRELLSPQYTTKWDCLPMIKC

Specific function: Involved in UV protection and mutation. Essential for induced (or SOS) mutagenesis. May modify the DNA replication machinery to allow bypass synthesis across a damaged template [H]

COG id: COG0389

COG function: function code L; Nucleotidyltransferase/DNA polymerase involved in DNA repair

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 umuC domain [H]

Homologues:

Organism=Escherichia coli, GI1787432, Length=225, Percent_Identity=36.8888888888889, Blast_Score=140, Evalue=8e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017961
- InterPro:   IPR001126
- InterPro:   IPR017963 [H]

Pfam domain/function: PF00817 IMS [H]

EC number: NA

Molecular weight: Translated: 24874; Mature: 24874

Theoretical pI: Translated: 9.83; Mature: 9.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIKTAYDLAQMPAGHARKQFSIEIERTVRELNGIECKQWDQARADKQQIFSTRSVGERI
CCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHH
TDFNSLLQALSKHVGIAAAKARAQGSSCKSMLLFASNSPFDDQPKSFKTLIHFPCATNST
HHHHHHHHHHHHHHCHHHHHHHHCCCCCCEEEEEECCCCCCCCCHHHHHHEECCCCCCCH
VEMTQAVSAAAPKLFREGVRYYKIGVGLINLVCDKRQQFDLFNAPKANPALMQALDGINF
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCHHHCCCCCCCCCCHHHHHHHCCCCC
RYGRDTLFLAAQGIEQKWAMRRELLSPQYTTKWDCLPMIKC
EECCCEEEEEHHCHHHHHHHHHHHCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MNIKTAYDLAQMPAGHARKQFSIEIERTVRELNGIECKQWDQARADKQQIFSTRSVGERI
CCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHH
TDFNSLLQALSKHVGIAAAKARAQGSSCKSMLLFASNSPFDDQPKSFKTLIHFPCATNST
HHHHHHHHHHHHHHCHHHHHHHHCCCCCCEEEEEECCCCCCCCCHHHHHHEECCCCCCCH
VEMTQAVSAAAPKLFREGVRYYKIGVGLINLVCDKRQQFDLFNAPKANPALMQALDGINF
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCHHHCCCCCCCCCCHHHHHHHCCCCC
RYGRDTLFLAAQGIEQKWAMRRELLSPQYTTKWDCLPMIKC
EECCCEEEEEHHCHHHHHHHHHHHCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Serine endopeptidases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2144275; 2203737; 11677609 [H]