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The map label for this gene is licA [H]

Identifier: 116874128

GI number: 116874128

Start: 2747047

End: 2747355

Strand: Direct

Name: licA [H]

Synonym: lwe2712

Alternate gene names: 116874128

Gene position: 2747047-2747355 (Clockwise)

Preceding gene: 116874127

Following gene: 116874133

Centisome position: 97.62

GC content: 38.83

Gene sequence:

>309_bases
ATGGATGAAATGGAAACAGTCATTTTTGGCATGATTAGCCAAGTTGGTTCTGCGAGAAGCAGTTACTTAGAAGGGCTTCG
TGCGGCTCGTGAAGGCAATTTCGAGGAAGCAGAAGCAAAACTACAAGAAGGTAGCGAAACTCTTGCAAATGGTCACCACG
AGCATCATAAACTAATCCAAAAAGAAGCTTCCGGTGAAAAAGTAGAAATTCAATTACTTTTAATCCATGCAGAAGACCTA
CTCATCACAACAGAAACATTAAGAGAAGTTGTCACTGAGTTCGTACATGTATATAAAAAAATAAGCTAA

Upstream 100 bases:

>100_bases
AGCTTTGGACTTCGTGACACAATTATCGAAACAGCTACACATAAAAACCAAGCTGGCCTACTCGGCGCAGTGTATCACTT
TTTACAGGAGGAAAATAAAC

Downstream 100 bases:

>100_bases
AGAAAAGCGTGTAGGTCACGAAAACCTACACGCTTTTCATTATTCTGTTTGTTCTTGATTATAATTTTTCTTCGCCATTG
CTTCCAGTAAAAAAAGTACC

Product: PTS system, IIA component

Products: protein histidine; sugar phosphate

Alternate protein names: EIIA-Lic; EIII-Lic; PTS system lichenan-specific EIIA component [H]

Number of amino acids: Translated: 102; Mature: 102

Protein sequence:

>102_residues
MDEMETVIFGMISQVGSARSSYLEGLRAAREGNFEEAEAKLQEGSETLANGHHEHHKLIQKEASGEKVEIQLLLIHAEDL
LITTETLREVVTEFVHVYKKIS

Sequences:

>Translated_102_residues
MDEMETVIFGMISQVGSARSSYLEGLRAAREGNFEEAEAKLQEGSETLANGHHEHHKLIQKEASGEKVEIQLLLIHAEDL
LITTETLREVVTEFVHVYKKIS
>Mature_102_residues
MDEMETVIFGMISQVGSARSSYLEGLRAAREGNFEEAEAKLQEGSETLANGHHEHHKLIQKEASGEKVEIQLLLIHAEDL
LITTETLREVVTEFVHVYKKIS

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system i

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIA type-3 domain [H]

Homologues:

Organism=Escherichia coli, GI1788031, Length=100, Percent_Identity=34, Blast_Score=67, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003188 [H]

Pfam domain/function: PF02255 PTS_IIA [H]

EC number: 2.7.1.69

Molecular weight: Translated: 11477; Mature: 11477

Theoretical pI: Translated: 4.80; Mature: 4.80

Prosite motif: PS51095 PTS_EIIA_TYPE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDEMETVIFGMISQVGSARSSYLEGLRAAREGNFEEAEAKLQEGSETLANGHHEHHKLIQ
CCHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHCCCHHHHHHHH
KEASGEKVEIQLLLIHAEDLLITTETLREVVTEFVHVYKKIS
HHCCCCEEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDEMETVIFGMISQVGSARSSYLEGLRAAREGNFEEAEAKLQEGSETLANGHHEHHKLIQ
CCHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHCCCHHHHHHHH
KEASGEKVEIQLLLIHAEDLLITTETLREVVTEFVHVYKKIS
HHCCCCEEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: protein N(pi)-phosphohistidine; sugar

Specific reaction: protein N(pi)-phosphohistidine + sugar = protein histidine + sugar phosphate

General reaction: Transferring phosphorus-containing groups [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8990303; 8969509; 9384377 [H]