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The map label for this gene is licA [H]

Identifier: 116874050

GI number: 116874050

Start: 2664442

End: 2664744

Strand: Direct

Name: licA [H]

Synonym: lwe2634

Alternate gene names: 116874050

Gene position: 2664442-2664744 (Clockwise)

Preceding gene: 116874049

Following gene: 116874055

Centisome position: 94.68

GC content: 36.96

Gene sequence:

>303_bases
ATGGATTTAGAACAAACAATTATGAGCTTGATCGTGTTCGGTGGTAATGCTAAAAGTGACGCTATGTTAGCTATTGATTC
CGCTAAAAAAGGGGATTTCGCTCAAGCAGACGAACAAATCGCCCAAGCAGAACAAGCACTACTTGAAGCGCATCATTCTC
AAACAAAACTTATACAAGGTGAAGCTCGTGGTGAAAAAACAGAAGTTTCCCTTCTACTTGTTCACGCACAAGATCACTTA
ATGAATGCAATCACTTTCAAAGATTTAGCGAAAGAAATTGTAGATCTTTATAAGAATAAATAA

Upstream 100 bases:

>100_bases
TCAAATTCAAGAGCTACGTCGCGAAAAAGAAGCACTTGCTGCTGAAGGCGTTACTGCAGAATAATTTTTACAAACCAAAA
CTTTAAGGACGTGTTTACAG

Downstream 100 bases:

>100_bases
GACCAAAAAACCAGCCGTCGTCATGACAGCTGGTTTTTTTCTTCTATTAAATTAGCATCTGATCGAATAATCGCTAACAC
TACGCCAACCGCAATAAAAT

Product: PTS system, beta-glucoside-specific, IIA component

Products: protein histidine; sugar phosphate

Alternate protein names: EIIA-Lic; EIII-Lic; PTS system lichenan-specific EIIA component [H]

Number of amino acids: Translated: 100; Mature: 100

Protein sequence:

>100_residues
MDLEQTIMSLIVFGGNAKSDAMLAIDSAKKGDFAQADEQIAQAEQALLEAHHSQTKLIQGEARGEKTEVSLLLVHAQDHL
MNAITFKDLAKEIVDLYKNK

Sequences:

>Translated_100_residues
MDLEQTIMSLIVFGGNAKSDAMLAIDSAKKGDFAQADEQIAQAEQALLEAHHSQTKLIQGEARGEKTEVSLLLVHAQDHL
MNAITFKDLAKEIVDLYKNK
>Mature_100_residues
MDLEQTIMSLIVFGGNAKSDAMLAIDSAKKGDFAQADEQIAQAEQALLEAHHSQTKLIQGEARGEKTEVSLLLVHAQDHL
MNAITFKDLAKEIVDLYKNK

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system i

COG id: COG1447

COG function: function code G; Phosphotransferase system cellobiose-specific component IIA

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIA type-3 domain [H]

Homologues:

Organism=Escherichia coli, GI1788031, Length=97, Percent_Identity=47.4226804123711, Blast_Score=87, Evalue=3e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003188 [H]

Pfam domain/function: PF02255 PTS_IIA [H]

EC number: 2.7.1.69

Molecular weight: Translated: 10994; Mature: 10994

Theoretical pI: Translated: 4.85; Mature: 4.85

Prosite motif: PS51095 PTS_EIIA_TYPE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLEQTIMSLIVFGGNAKSDAMLAIDSAKKGDFAQADEQIAQAEQALLEAHHSQTKLIQG
CCHHHHHHHHHHHCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
EARGEKTEVSLLLVHAQDHLMNAITFKDLAKEIVDLYKNK
CCCCCCCEEEEEEEECHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MDLEQTIMSLIVFGGNAKSDAMLAIDSAKKGDFAQADEQIAQAEQALLEAHHSQTKLIQG
CCHHHHHHHHHHHCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
EARGEKTEVSLLLVHAQDHLMNAITFKDLAKEIVDLYKNK
CCCCCCCEEEEEEEECHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: protein N(pi)-phosphohistidine; sugar

Specific reaction: protein N(pi)-phosphohistidine + sugar = protein histidine + sugar phosphate

General reaction: Transferring phosphorus-containing groups [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8990303; 8969509; 9384377 [H]