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The map label for this gene is licC [H]

Identifier: 116874049

GI number: 116874049

Start: 2663098

End: 2664405

Strand: Direct

Name: licC [H]

Synonym: lwe2633

Alternate gene names: 116874049

Gene position: 2663098-2664405 (Clockwise)

Preceding gene: 116874048

Following gene: 116874050

Centisome position: 94.63

GC content: 40.06

Gene sequence:

>1308_bases
ATGAATGGTTTTATCGCATTTATGGAAAAATATTTCATTCCGTACGCAGCCAAAATTGGTGGCCAACGTCATTTAGTAGC
AATTCGTGATGGTTTCATTACAACTATGCCACTAATGATTCTAGGATCTTTCGCTGTTTTAATTAACAACTTCCCAATTC
CAGCTTACCAAAAATTCATGAATAACTTATTTGGTGAAGGAACTTGGCAAGCATTTGGCGGAAACGTTTGGAACGGTACT
TTTGCTATCTTAGCATTACTTATCGCTTTCACAGTAGCTTACAACTTAGCGAAATCATATGATAAAGATCCACTTTCATC
CGCAGTAGTTTCTGTCGCTACATTCTTCACTATTGGCGCAATTGCTCCAGGTGCAGACGGCGTCCCTAACACTGGTGGTT
TAGGATCAACTGGTCTTTTCTTAGCATTAATTATTGCAATTCTTTCCACTGAGATTTTCACTCGCTTGAGTGGTAGCCCG
AAATTAATTATCAACATGCCTGATGGTGTTCCACCGGCAGTTTCTCGTTCATTCGCAGCTTTATTCCCTGCAATGATCAC
AGTTTCTATCTTTGGTCTTATCACTGCTTTCTTCCAAGCAGCAGGTGTAAGTAACTTAGTAATTTCTTTCTATGAATTAG
TTCAAGAACCGTTCATGGGTCTTGCAAACTCCTTGCCAGCAGCATTACTACTCGCATTTGTTTCTGCTTTCCTTTGGTTC
TTTGGTTTACACGGAGCGAATATTATCGACCCGTTCATGCAAACAATCAATATCCCAGCTATTACTGCTAACCAAGATGC
ATTAAAAGCTGGTAAAGAACTTCCTTATATCGTTAACAAACCTTTCTTTGACTCTTTCGTTAACTTAGGCGGAACTGGGG
CAACTATCGGTTTAATCATTGCTATCTTTATCGTAGCTCGTAAACATAAAGCGTATATGACAGTTTCTAAATTGTCTGCA
GCGCCAGGTATTTTCAACATTAACGAACCTATGATGTTTGGTCTTCCAATCGTCTTGAATCCAATTATGTTCATTCCATA
CATCTTGGCACCACTTGTACTTGTAACTGTAGCTTACTTTGCAACAGCTATTGGTTGGGTACCAGCTTGTACTATCGTAA
CTCCTTGGACTACACCACCAATTATCGGTGGAGCACTTGCAACACAAAGTATCGCTGGTGGCGTACTTGCAGCTGTAAAC
TTAGGATTATCTATTCTAATCTTCCTTCCATTCGCGAAAATTGCTCAAATTCAAGAGCTACGTCGCGAAAAAGAAGCACT
TGCTGCTGAAGGCGTTACTGCAGAATAA

Upstream 100 bases:

>100_bases
TAAAAAACTAAAGAGGTATAGTAATAACATCATGTTTTAGAAATTATGTATTTGTCTTAACCCATGCTATTACTTTATCC
TCAAAAAAGGAGAATAAAAA

Downstream 100 bases:

>100_bases
TTTTTACAAACCAAAACTTTAAGGACGTGTTTACAGATGGATTTAGAACAAACAATTATGAGCTTGATCGTGTTCGGTGG
TAATGCTAAAAGTGACGCTA

Product: PTS system, beta-glucoside-specific, IIC component

Products: pyruvate; diacetylchitobiose-6-phosphate [Cytoplasm]; cellobiose-6-phosphate [Cytoplasm] [C]

Alternate protein names: EIIC-Lic; PTS system lichenan-specific EIIC component [H]

Number of amino acids: Translated: 435; Mature: 435

Protein sequence:

>435_residues
MNGFIAFMEKYFIPYAAKIGGQRHLVAIRDGFITTMPLMILGSFAVLINNFPIPAYQKFMNNLFGEGTWQAFGGNVWNGT
FAILALLIAFTVAYNLAKSYDKDPLSSAVVSVATFFTIGAIAPGADGVPNTGGLGSTGLFLALIIAILSTEIFTRLSGSP
KLIINMPDGVPPAVSRSFAALFPAMITVSIFGLITAFFQAAGVSNLVISFYELVQEPFMGLANSLPAALLLAFVSAFLWF
FGLHGANIIDPFMQTINIPAITANQDALKAGKELPYIVNKPFFDSFVNLGGTGATIGLIIAIFIVARKHKAYMTVSKLSA
APGIFNINEPMMFGLPIVLNPIMFIPYILAPLVLVTVAYFATAIGWVPACTIVTPWTTPPIIGGALATQSIAGGVLAAVN
LGLSILIFLPFAKIAQIQELRREKEALAAEGVTAE

Sequences:

>Translated_435_residues
MNGFIAFMEKYFIPYAAKIGGQRHLVAIRDGFITTMPLMILGSFAVLINNFPIPAYQKFMNNLFGEGTWQAFGGNVWNGT
FAILALLIAFTVAYNLAKSYDKDPLSSAVVSVATFFTIGAIAPGADGVPNTGGLGSTGLFLALIIAILSTEIFTRLSGSP
KLIINMPDGVPPAVSRSFAALFPAMITVSIFGLITAFFQAAGVSNLVISFYELVQEPFMGLANSLPAALLLAFVSAFLWF
FGLHGANIIDPFMQTINIPAITANQDALKAGKELPYIVNKPFFDSFVNLGGTGATIGLIIAIFIVARKHKAYMTVSKLSA
APGIFNINEPMMFGLPIVLNPIMFIPYILAPLVLVTVAYFATAIGWVPACTIVTPWTTPPIIGGALATQSIAGGVLAAVN
LGLSILIFLPFAKIAQIQELRREKEALAAEGVTAE
>Mature_435_residues
MNGFIAFMEKYFIPYAAKIGGQRHLVAIRDGFITTMPLMILGSFAVLINNFPIPAYQKFMNNLFGEGTWQAFGGNVWNGT
FAILALLIAFTVAYNLAKSYDKDPLSSAVVSVATFFTIGAIAPGADGVPNTGGLGSTGLFLALIIAILSTEIFTRLSGSP
KLIINMPDGVPPAVSRSFAALFPAMITVSIFGLITAFFQAAGVSNLVISFYELVQEPFMGLANSLPAALLLAFVSAFLWF
FGLHGANIIDPFMQTINIPAITANQDALKAGKELPYIVNKPFFDSFVNLGGTGATIGLIIAIFIVARKHKAYMTVSKLSA
APGIFNINEPMMFGLPIVLNPIMFIPYILAPLVLVTVAYFATAIGWVPACTIVTPWTTPPIIGGALATQSIAGGVLAAVN
LGLSILIFLPFAKIAQIQELRREKEALAAEGVTAE

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system i

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-3 domain [H]

Homologues:

Organism=Escherichia coli, GI1788032, Length=457, Percent_Identity=36.1050328227571, Blast_Score=244, Evalue=1e-65,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003352
- InterPro:   IPR004796
- InterPro:   IPR004501 [H]

Pfam domain/function: PF02378 PTS_EIIC [H]

EC number: NA

Molecular weight: Translated: 46259; Mature: 46259

Theoretical pI: Translated: 8.38; Mature: 8.38

Prosite motif: PS51105 PTS_EIIC_TYPE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNGFIAFMEKYFIPYAAKIGGQRHLVAIRDGFITTMPLMILGSFAVLINNFPIPAYQKFM
CCHHHHHHHHHHCCHHHHCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
NNLFGEGTWQAFGGNVWNGTFAILALLIAFTVAYNLAKSYDKDPLSSAVVSVATFFTIGA
HHHCCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHC
IAPGADGVPNTGGLGSTGLFLALIIAILSTEIFTRLSGSPKLIINMPDGVPPAVSRSFAA
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHH
LFPAMITVSIFGLITAFFQAAGVSNLVISFYELVQEPFMGLANSLPAALLLAFVSAFLWF
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FGLHGANIIDPFMQTINIPAITANQDALKAGKELPYIVNKPFFDSFVNLGGTGATIGLII
HHCCCCHHHHHHHHHHCCCEEECCHHHHHCCCCCCCCCCCCHHHHHHHCCCCHHHHHHHH
AIFIVARKHKAYMTVSKLSAAPGIFNINEPMMFGLPIVLNPIMFIPYILAPLVLVTVAYF
HHHHHHHHHHHHHHHHHHHCCCCCEECCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
ATAIGWVPACTIVTPWTTPPIIGGALATQSIAGGVLAAVNLGLSILIFLPFAKIAQIQEL
HHHHHHHHHCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RREKEALAAEGVTAE
HHHHHHHHHCCCCCC
>Mature Secondary Structure
MNGFIAFMEKYFIPYAAKIGGQRHLVAIRDGFITTMPLMILGSFAVLINNFPIPAYQKFM
CCHHHHHHHHHHCCHHHHCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
NNLFGEGTWQAFGGNVWNGTFAILALLIAFTVAYNLAKSYDKDPLSSAVVSVATFFTIGA
HHHCCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHC
IAPGADGVPNTGGLGSTGLFLALIIAILSTEIFTRLSGSPKLIINMPDGVPPAVSRSFAA
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHH
LFPAMITVSIFGLITAFFQAAGVSNLVISFYELVQEPFMGLANSLPAALLLAFVSAFLWF
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FGLHGANIIDPFMQTINIPAITANQDALKAGKELPYIVNKPFFDSFVNLGGTGATIGLII
HHCCCCHHHHHHHHHHCCCEEECCHHHHHCCCCCCCCCCCCHHHHHHHCCCCHHHHHHHH
AIFIVARKHKAYMTVSKLSAAPGIFNINEPMMFGLPIVLNPIMFIPYILAPLVLVTVAYF
HHHHHHHHHHHHHHHHHHHCCCCCEECCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
ATAIGWVPACTIVTPWTTPPIIGGALATQSIAGGVLAAVNLGLSILIFLPFAKIAQIQEL
HHHHHHHHHCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RREKEALAAEGVTAE
HHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: diacetylchitobiose [Periplasm]; phosphoenolpyruvate; cellobiose [Periplasm] [C]

Specific reaction: phosphoenolpyruvate + diacetylchitobiose [Periplasm] = pyruvate + diacetylchitobiose-6-phosphate [Cytoplasm] phosphoenolpyruvate + cellobiose [Periplasm] = cellobiose-6-phosphate [Cytoplasm] + pyruvate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8990303; 8969509; 9384377 [H]