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The map label for this gene is mrpG [H]

Identifier: 116873749

GI number: 116873749

Start: 2378540

End: 2379133

Strand: Direct

Name: mrpG [H]

Synonym: lwe2333

Alternate gene names: 116873749

Gene position: 2378540-2379133 (Clockwise)

Preceding gene: 116873748

Following gene: 116873751

Centisome position: 84.52

GC content: 38.72

Gene sequence:

>594_bases
GTGAACGTGATAATTGAGATTATTATTTCTATCATGATTTTAATTGGTGGTTTGCTTAGTATTCTTGCTGCAATCGGCGT
TATTAGACTACCAGATGTGTATACTAGAACTCATGCAGCTGGGATTAGTAATACATTTGGCGTTAGTTTACTTCTTTTTG
CAACGGTTGGTTATTTTTTCCACTCAGGTGAAGGTTTTAATGCGCGAGTACTTCTGGCAGTATTGTTTATTTTCTTAACT
ACACCAGTGGCTTCCCATCTTATTAACCGGGCCGCTTATGATACAGGTGTTCCGCTAGCTATTCGAATTCGTGACCAATT
GCGTTCCGTGAAAAAAAACGACATCAAGAAGAAGAAAAGTCTTATTATTCGTCAAGAACAAATTGAAAAAGCACGACAAG
AACGAGAAGAATTGGAAGAACGAATGGAATGGGAACGACGAGAAGAAAAAATTGATGAGCGGGAGGATCAAGAGGAACAA
GATCGTGAACGCGAGGAACAAACGATTGAAGAACAGTCAGATGATTCTGAGCATGAAATCATTGAGCAAGATGAAAGTGA
AACAGAAGCAGACGAAGATGAAACAGAGAAATAA

Upstream 100 bases:

>100_bases
ACACATGCCTTTCTGGATGTTATTTTACTTATTGCGCTTCTTGCCTTTATTGGAACGGTTTCCTTTGCCAAATTTATTGA
GAAAGGAAAGGTGATTGACC

Downstream 100 bases:

>100_bases
AACAAGCATGGCAAGAGTTCATCATCTGATCTCTGCCATGCTTATTATTTTCGCTTCTTTTTAACGGCAATCGTACATCT
ACTAATACAAATTAATTTAT

Product: putative monovalent cation/H+ antiporter subunit G

Products: NA

Alternate protein names: Mrp complex subunit G; Multiple resistance and pH homeostasis protein G [H]

Number of amino acids: Translated: 197; Mature: 197

Protein sequence:

>197_residues
MNVIIEIIISIMILIGGLLSILAAIGVIRLPDVYTRTHAAGISNTFGVSLLLFATVGYFFHSGEGFNARVLLAVLFIFLT
TPVASHLINRAAYDTGVPLAIRIRDQLRSVKKNDIKKKKSLIIRQEQIEKARQEREELEERMEWERREEKIDEREDQEEQ
DREREEQTIEEQSDDSEHEIIEQDESETEADEDETEK

Sequences:

>Translated_197_residues
MNVIIEIIISIMILIGGLLSILAAIGVIRLPDVYTRTHAAGISNTFGVSLLLFATVGYFFHSGEGFNARVLLAVLFIFLT
TPVASHLINRAAYDTGVPLAIRIRDQLRSVKKNDIKKKKSLIIRQEQIEKARQEREELEERMEWERREEKIDEREDQEEQ
DREREEQTIEEQSDDSEHEIIEQDESETEADEDETEK
>Mature_197_residues
MNVIIEIIISIMILIGGLLSILAAIGVIRLPDVYTRTHAAGISNTFGVSLLLFATVGYFFHSGEGFNARVLLAVLFIFLT
TPVASHLINRAAYDTGVPLAIRIRDQLRSVKKNDIKKKKSLIIRQEQIEKARQEREELEERMEWERREEKIDEREDQEEQ
DREREEQTIEEQSDDSEHEIIEQDESETEADEDETEK

Specific function: Mnh complex is a Na(+)Li(+)/H(+) antiporter involved in Na(+) and/or Li(+) excretion and Na(+) resistance. Na(+)/H(+) antiport consumes a transmembrane electrical potential, and is thus inferred to be electrogenic. Does not transport K(+), Ca(2+) or Mg(2+

COG id: COG1320

COG function: function code P; Multisubunit Na+/H+ antiporter, MnhG subunit

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CPA3 antiporters (TC 2.A.63) subunit G family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005133 [H]

Pfam domain/function: PF03334 PhaG_MnhG_YufB [H]

EC number: NA

Molecular weight: Translated: 22755; Mature: 22755

Theoretical pI: Translated: 4.37; Mature: 4.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVIIEIIISIMILIGGLLSILAAIGVIRLPDVYTRTHAAGISNTFGVSLLLFATVGYFF
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
HSGEGFNARVLLAVLFIFLTTPVASHLINRAAYDTGVPLAIRIRDQLRSVKKNDIKKKKS
HCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
LIIRQEQIEKARQEREELEERMEWERREEKIDEREDQEEQDREREEQTIEEQSDDSEHEI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCHHHH
IEQDESETEADEDETEK
HHCCCCCCCCCCCCCCC
>Mature Secondary Structure
MNVIIEIIISIMILIGGLLSILAAIGVIRLPDVYTRTHAAGISNTFGVSLLLFATVGYFF
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
HSGEGFNARVLLAVLFIFLTTPVASHLINRAAYDTGVPLAIRIRDQLRSVKKNDIKKKKS
HCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
LIIRQEQIEKARQEREELEERMEWERREEKIDEREDQEEQDREREEQTIEEQSDDSEHEI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCHHHH
IEQDESETEADEDETEK
HHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11356194 [H]