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The map label for this gene is mrpF [H]

Identifier: 116873748

GI number: 116873748

Start: 2378269

End: 2378556

Strand: Direct

Name: mrpF [H]

Synonym: lwe2332

Alternate gene names: 116873748

Gene position: 2378269-2378556 (Clockwise)

Preceding gene: 116873747

Following gene: 116873749

Centisome position: 84.51

GC content: 35.42

Gene sequence:

>288_bases
ATGATTATTCAAATAGCTTTATCCATTGGTTTACTCCTTTATTCAATTTCAACTTTCTTGTATCTTTACCGTATTTTAAA
AGGACCAACTACTTCTGACAAAGTGGTGGCGCTCGATTCTATCGGAATGAATTTAGTGGCAATTGTTGCTCTACTTTCGA
TGTTTTATGACACACATGCCTTTCTGGATGTTATTTTACTTATTGCGCTTCTTGCCTTTATTGGAACGGTTTCCTTTGCC
AAATTTATTGAGAAAGGAAAGGTGATTGACCGTGAACGTGATAATTGA

Upstream 100 bases:

>100_bases
AAGCAATCTATGTGCATTCACTCCATGTACCCAATATTGAAGAAGAAATTGCGACGATTCGTAAGTCATATGAAGGTGCG
ATTATGGAGGTGTTCCACGG

Downstream 100 bases:

>100_bases
GATTATTATTTCTATCATGATTTTAATTGGTGGTTTGCTTAGTATTCTTGCTGCAATCGGCGTTATTAGACTACCAGATG
TGTATACTAGAACTCATGCA

Product: putative monovalent cation/H+ antiporter subunit F

Products: NA

Alternate protein names: Mrp complex subunit F; Multiple resistance and pH homeostasis protein F; Sodium-cholate efflux protein MrpF [H]

Number of amino acids: Translated: 95; Mature: 95

Protein sequence:

>95_residues
MIIQIALSIGLLLYSISTFLYLYRILKGPTTSDKVVALDSIGMNLVAIVALLSMFYDTHAFLDVILLIALLAFIGTVSFA
KFIEKGKVIDRERDN

Sequences:

>Translated_95_residues
MIIQIALSIGLLLYSISTFLYLYRILKGPTTSDKVVALDSIGMNLVAIVALLSMFYDTHAFLDVILLIALLAFIGTVSFA
KFIEKGKVIDRERDN
>Mature_95_residues
MIIQIALSIGLLLYSISTFLYLYRILKGPTTSDKVVALDSIGMNLVAIVALLSMFYDTHAFLDVILLIALLAFIGTVSFA
KFIEKGKVIDRERDN

Specific function: Involved in cholate and Na(+) efflux activities, which may be mechanistically coupled. Does not require other mrp proteins for its own function [H]

COG id: COG2212

COG function: function code P; Multisubunit Na+/H+ antiporter, MnhF subunit

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CPA3 antiporters (TC 2.A.63) subunit F family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007208 [H]

Pfam domain/function: PF04066 MrpF_PhaF [H]

EC number: NA

Molecular weight: Translated: 10541; Mature: 10541

Theoretical pI: Translated: 7.51; Mature: 7.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIIQIALSIGLLLYSISTFLYLYRILKGPTTSDKVVALDSIGMNLVAIVALLSMFYDTHA
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEHHHHCCHHHHHHHHHHHHHHHHHH
FLDVILLIALLAFIGTVSFAKFIEKGKVIDRERDN
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MIIQIALSIGLLLYSISTFLYLYRILKGPTTSDKVVALDSIGMNLVAIVALLSMFYDTHA
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEHHHHCCHHHHHHHHHHHHHHHHHH
FLDVILLIALLAFIGTVSFAKFIEKGKVIDRERDN
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9274030; 9384377; 10198001; 11004162; 11356194 [H]