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The map label for this gene is comK [H]

Identifier: 116873701

GI number: 116873701

Start: 2325982

End: 2326581

Strand: Direct

Name: comK [H]

Synonym: lwe2285

Alternate gene names: 116873701

Gene position: 2325982-2326581 (Clockwise)

Preceding gene: 116873694

Following gene: 116873706

Centisome position: 82.65

GC content: 34.33

Gene sequence:

>600_bases
ATGAAAAAAGAACCAATTAGTACTCAGTTTTATGAAGTAAACCCACACACGATGATTATTTTTCCAAAAAAGTCTGGAAG
TATAGTCTATTCAGAAATTTATGAAGTTGATTCTCATTATACTTCTAAATTTACCCCTTTTGAGCTAATTAAAACCAGTT
GTAATTTTTTCGGTTCGAGCTATGAGGGTCGCAAAGAGGGAACCAAGCATTTGATTGGAGTAACCCATAAGCCACCCATT
ATTATTGACCCAGTTACCTCCACTTATGTATTTCCTACTGCTGCACCAAGTTCAGAAGATTGTATTTGGATTTTCCCGCA
GCATATCAAAGACTATAAAACAGTTGGTTATAATCATACTTTAATAACATTTTCTAATCAACAAACAGTTGAAATTGATA
TGTCTCTAGCTTCCTTTAATAACCAAATCGCTAGAACCTCCATGCTACATATGAAATTTTCTCAAAAGATGCGTATGATG
GAGAGCAATTTCCCTTCCATGAATATGTTTTTCCCTCCCGCTACACTCGCCGCTGAAACAAGACGTTATTATAATACAAT
GATTTCTGAAAATAAAGATTCTGATGACAAGGATGAATAA

Upstream 100 bases:

>100_bases
CTAACTTTGATGCTTAGATGATCCATATAATTTTTGCGCATTATGCAATGATTTAGGTTTCTTCTTAGACATAAATACAA
ACATAGGAGAGTTGAATGAA

Downstream 100 bases:

>100_bases
AGCTTAAAATCCAAGAAAAACCAGATATACACTCGTATATCTGGTTTCCATTATTATTTCTTATCTTCAATTGCATCTGC
AATTCGTTTTAACATTAACA

Product: competence transcription factor

Products: NA

Alternate protein names: CTF; Competence protein K [H]

Number of amino acids: Translated: 199; Mature: 199

Protein sequence:

>199_residues
MKKEPISTQFYEVNPHTMIIFPKKSGSIVYSEIYEVDSHYTSKFTPFELIKTSCNFFGSSYEGRKEGTKHLIGVTHKPPI
IIDPVTSTYVFPTAAPSSEDCIWIFPQHIKDYKTVGYNHTLITFSNQQTVEIDMSLASFNNQIARTSMLHMKFSQKMRMM
ESNFPSMNMFFPPATLAAETRRYYNTMISENKDSDDKDE

Sequences:

>Translated_199_residues
MKKEPISTQFYEVNPHTMIIFPKKSGSIVYSEIYEVDSHYTSKFTPFELIKTSCNFFGSSYEGRKEGTKHLIGVTHKPPI
IIDPVTSTYVFPTAAPSSEDCIWIFPQHIKDYKTVGYNHTLITFSNQQTVEIDMSLASFNNQIARTSMLHMKFSQKMRMM
ESNFPSMNMFFPPATLAAETRRYYNTMISENKDSDDKDE
>Mature_199_residues
MKKEPISTQFYEVNPHTMIIFPKKSGSIVYSEIYEVDSHYTSKFTPFELIKTSCNFFGSSYEGRKEGTKHLIGVTHKPPI
IIDPVTSTYVFPTAAPSSEDCIWIFPQHIKDYKTVGYNHTLITFSNQQTVEIDMSLASFNNQIARTSMLHMKFSQKMRMM
ESNFPSMNMFFPPATLAAETRRYYNTMISENKDSDDKDE

Specific function: Intermediate regulatory gene required for the expression of the late competence genes comC, comE, comG and the bdbDC operon. Receives signals from SrfA, and possibly other regulatory COM genes, and transduces these signals to the late COM genes [H]

COG id: COG4903

COG function: function code K; Genetic competence transcription factor

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010461 [H]

Pfam domain/function: PF06338 ComK [H]

EC number: NA

Molecular weight: Translated: 22980; Mature: 22980

Theoretical pI: Translated: 6.88; Mature: 6.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
5.5 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
5.5 %Met     (Mature Protein)
6.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKEPISTQFYEVNPHTMIIFPKKSGSIVYSEIYEVDSHYTSKFTPFELIKTSCNFFGSS
CCCCCCCCEEEEECCCEEEEEECCCCCEEEHHHHHHCCCCCCCCCHHHHHHHHHHHCCCC
YEGRKEGTKHLIGVTHKPPIIIDPVTSTYVFPTAAPSSEDCIWIFPQHIKDYKTVGYNHT
CCCCCCCCCEEEEECCCCCEEECCCCCEEEEECCCCCCCCEEEECHHHHCHHHHCCCCEE
LITFSNQQTVEIDMSLASFNNQIARTSMLHMKFSQKMRMMESNFPSMNMFFPPATLAAET
EEEECCCEEEEEEEEHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCHHHHHHH
RRYYNTMISENKDSDDKDE
HHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MKKEPISTQFYEVNPHTMIIFPKKSGSIVYSEIYEVDSHYTSKFTPFELIKTSCNFFGSS
CCCCCCCCEEEEECCCEEEEEECCCCCEEEHHHHHHCCCCCCCCCHHHHHHHHHHHCCCC
YEGRKEGTKHLIGVTHKPPIIIDPVTSTYVFPTAAPSSEDCIWIFPQHIKDYKTVGYNHT
CCCCCCCCCEEEEECCCCCEEECCCCCEEEEECCCCCCCCEEEECHHHHCHHHHCCCCEE
LITFSNQQTVEIDMSLASFNNQIARTSMLHMKFSQKMRMMESNFPSMNMFFPPATLAAET
EEEECCCEEEEEEEEHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCHHHHHHH
RRYYNTMISENKDSDDKDE
HHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8196543; 9579061; 9384377; 7783616; 11744713 [H]