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The map label for this gene is yitU [H]

Identifier: 116873694

GI number: 116873694

Start: 2315060

End: 2315872

Strand: Direct

Name: yitU [H]

Synonym: lwe2278

Alternate gene names: 116873694

Gene position: 2315060-2315872 (Clockwise)

Preceding gene: 116873690

Following gene: 116873701

Centisome position: 82.27

GC content: 35.92

Gene sequence:

>813_bases
ATGTCTAAAAAATTAATTGTACTAGATCTTGACGGCACAACCCTTAGAGATGATTTGACTATCTCTTCGCATACAAAAAA
CACATTAGAAAAAGCACGCATGGCAGGTCATGAAGTAATGATTGCAACTGGTCGCCCTTATCGAATTAGTGGATCATATT
ATCATGAACTGGGATTAACAACTCCAATAGTTAACTTTAATGGCGCTGTTTACCATCATCCAAGACTCTCTACTTTCGCT
GAAGGTTATCATCATGCCATTGATTTACAAGTAGTTCGCGAGTTACTAGATTTCTCAAATGACTTTTCGTTAGATAATAT
CGCAGCCGAAGTGCAAGATAATGTCTTTTTAAAAGAACGTAATAATAGCGTTCCTGAAACATTCCATTTAGGAACAGAAA
ATATTGTATTTGGAAATATTCGCGATGCCATAACATCCGATGCCACATCACTACTATTTTTTGGAAAAATAGATCAACTA
AATTTAATTAGCAAACATTTAGATGAATCACTTTCTGGTGTTATCTCACACCATACTTGGGGTGCTTCTGCTTGGCCTGC
TGTTGAAATTATCAAATTCGGTATCCATAAAGCAATTGGTGTAAAAGCTGCTGCTAAAACACTAGGTTTTGATCGCAAAG
ATATTATCGCTTTTGGTGATGAAACAAACGATTTACAAATGCTTGATTACGCTGGTGTTGGAGTTGCAATGGGCAATGCA
GCTGAACCTGTTAAAAATGTAGCAAATGTAGTAACTGCTTCTAACCAAGATGACGGAATTGCTCTATATCTAGAAGAAAA
CTTAAATCTATAA

Upstream 100 bases:

>100_bases
TCATTTACAAATTTGAGATTAACGACTATCATTGATATGTGCCCTTATTTTAGCATGAAGGGGCAGCTTGAACCAACCAT
ATGAATTAAAGGAGCAAAAT

Downstream 100 bases:

>100_bases
TTAAAAGCTGCAAGTATGGCCTTACAAAAGTTAGAATTTCTAATTTTTTGTTTAGCCATTACCTTGCAGCTTTTTTACAT
CATTTTATTTTTATACATTG

Product: HAD family hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 270; Mature: 269

Protein sequence:

>270_residues
MSKKLIVLDLDGTTLRDDLTISSHTKNTLEKARMAGHEVMIATGRPYRISGSYYHELGLTTPIVNFNGAVYHHPRLSTFA
EGYHHAIDLQVVRELLDFSNDFSLDNIAAEVQDNVFLKERNNSVPETFHLGTENIVFGNIRDAITSDATSLLFFGKIDQL
NLISKHLDESLSGVISHHTWGASAWPAVEIIKFGIHKAIGVKAAAKTLGFDRKDIIAFGDETNDLQMLDYAGVGVAMGNA
AEPVKNVANVVTASNQDDGIALYLEENLNL

Sequences:

>Translated_270_residues
MSKKLIVLDLDGTTLRDDLTISSHTKNTLEKARMAGHEVMIATGRPYRISGSYYHELGLTTPIVNFNGAVYHHPRLSTFA
EGYHHAIDLQVVRELLDFSNDFSLDNIAAEVQDNVFLKERNNSVPETFHLGTENIVFGNIRDAITSDATSLLFFGKIDQL
NLISKHLDESLSGVISHHTWGASAWPAVEIIKFGIHKAIGVKAAAKTLGFDRKDIIAFGDETNDLQMLDYAGVGVAMGNA
AEPVKNVANVVTASNQDDGIALYLEENLNL
>Mature_269_residues
SKKLIVLDLDGTTLRDDLTISSHTKNTLEKARMAGHEVMIATGRPYRISGSYYHELGLTTPIVNFNGAVYHHPRLSTFAE
GYHHAIDLQVVRELLDFSNDFSLDNIAAEVQDNVFLKERNNSVPETFHLGTENIVFGNIRDAITSDATSLLFFGKIDQLN
LISKHLDESLSGVISHHTWGASAWPAVEIIKFGIHKAIGVKAAAKTLGFDRKDIIAFGDETNDLQMLDYAGVGVAMGNAA
EPVKNVANVVTASNQDDGIALYLEENLNL

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. Cof family [H]

Homologues:

Organism=Escherichia coli, GI2367265, Length=280, Percent_Identity=32.8571428571429, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1786982, Length=280, Percent_Identity=27.8571428571429, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI48994981, Length=273, Percent_Identity=27.4725274725275, Blast_Score=84, Evalue=9e-18,
Organism=Escherichia coli, GI1787043, Length=265, Percent_Identity=29.0566037735849, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI87081790, Length=266, Percent_Identity=26.6917293233083, Blast_Score=66, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023214
- InterPro:   IPR013200
- InterPro:   IPR006379
- InterPro:   IPR000150 [H]

Pfam domain/function: PF08282 Hydrolase_3 [H]

EC number: NA

Molecular weight: Translated: 29621; Mature: 29490

Theoretical pI: Translated: 5.29; Mature: 5.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKKLIVLDLDGTTLRDDLTISSHTKNTLEKARMAGHEVMIATGRPYRISGSYYHELGLT
CCCCEEEEECCCCEEECCCEECCCHHHHHHHHHHCCCEEEEECCCCEEECCCEEEECCCC
TPIVNFNGAVYHHPRLSTFAEGYHHAIDLQVVRELLDFSNDFSLDNIAAEVQDNVFLKER
CCEEECCCEEEECCCHHHHHHHHHHEEHHHHHHHHHCCCCCCCHHHHHHHHHCCEEEEEC
NNSVPETFHLGTENIVFGNIRDAITSDATSLLFFGKIDQLNLISKHLDESLSGVISHHTW
CCCCCCEEECCCCCEEECCHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHCCC
GASAWPAVEIIKFGIHKAIGVKAAAKTLGFDRKDIIAFGDETNDLQMLDYAGVGVAMGNA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCEEEEEECCCCEEECCC
AEPVKNVANVVTASNQDDGIALYLEENLNL
HHHHHHHHHHHCCCCCCCCEEEEEECCCCC
>Mature Secondary Structure 
SKKLIVLDLDGTTLRDDLTISSHTKNTLEKARMAGHEVMIATGRPYRISGSYYHELGLT
CCCEEEEECCCCEEECCCEECCCHHHHHHHHHHCCCEEEEECCCCEEECCCEEEECCCC
TPIVNFNGAVYHHPRLSTFAEGYHHAIDLQVVRELLDFSNDFSLDNIAAEVQDNVFLKER
CCEEECCCEEEECCCHHHHHHHHHHEEHHHHHHHHHCCCCCCCHHHHHHHHHCCEEEEEC
NNSVPETFHLGTENIVFGNIRDAITSDATSLLFFGKIDQLNLISKHLDESLSGVISHHTW
CCCCCCEEECCCCCEEECCHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHCCC
GASAWPAVEIIKFGIHKAIGVKAAAKTLGFDRKDIIAFGDETNDLQMLDYAGVGVAMGNA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCEEEEEECCCCEEECCC
AEPVKNVANVVTASNQDDGIALYLEENLNL
HHHHHHHHHHHCCCCCCCCEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9353931; 9025291; 9384377 [H]