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The map label for this gene is baiH [H]

Identifier: 116873668

GI number: 116873668

Start: 2291245

End: 2293170

Strand: Direct

Name: baiH [H]

Synonym: lwe2252

Alternate gene names: 116873668

Gene position: 2291245-2293170 (Clockwise)

Preceding gene: 116873667

Following gene: 116873669

Centisome position: 81.42

GC content: 41.23

Gene sequence:

>1926_bases
TTGAAATTTAATTCGATGTTCTCACCTATCGATATTGGTCCGATGAAAGTACCTAATCGGTTTGTTGTATCTCCAATGTG
TAATAACTATGCGAATACAGATGGCACTTTATCAGATACTTCACTTGCATATTACAAAGAACGAGCTCTCGGCGGCTTTG
GTTTAATTACTTTTGAAGCAACTGTAGTAGATGTTCGGGCAAAAGGTGGCGCAAACAAGGCTTGTCTTTATAGTGATCAC
CAAATCGCTAGTTTTAAACGAGTGATTGATGTTTGTCATGATGCCGGAGCTAAAATTTCTGTGCAATTACAGCATGCTGG
ACCTGAAGGGAACTCCAAAGTTTCTGGATATCCTTTAAAAGCAGCCTCTGCTATTGCTTCAGCTGAAGGTCGTAACACGC
CAGAAGCAATTTCACGGGAAGAACTCTATGAATTAATTGAACTTTATGGTGAAGCCGCATTACGCGCAAAAAAAGCTGGT
GCTGATGCAGTTGAAATTCACTGTGCTCATGGATATTTAGTGAGTAGCTTCTTATCTGGGCGAACAAACAAACGTGTAGA
CGAATTTGGAGGTTGCTTTGAAAACCGAATGCGCTTGCCAAGACTCATTATTGAAAGTATTCGTAAACGAGTTGGTCATT
CTATTGCTATATTATGCCGAATTAATAGCACAGATGGCGTAGAAGGCGGATTAAGTGTACAAGATAGCGCTACAGTTGCA
GCTTATTTAGAAGATTGTGGTTTAGATGGACTTCATGTTTCTCGTAGCGTTCATATTCGCGATGAATATATGTGGGCGCC
TACTGTTTTACATGCAGGATTTAGTTCTGATCTTGTCACACAAATTAAACGTGCAGTTTCTATCCCAGTTATTACTGTTG
GTCGTTTTACCGAGCCACATTATGCTGAATTAATGGTTCGTGAAGGACGTGCGGATTTAGTAGCATTTGGACGCCAATCT
TTAGCCGACCCAGAAACACCAAATAAAGCTGCAGCTGGAAAACTCGATGAACTGCTTCCTTGTATCGCCTGTCTTCAAGG
TTGTGTGGCAAACATGTATGCCGGAAAACCGATTACTTGTTTAGTTAACCCATTACTTGGCCGTGAATCCGAAGCATATT
TACCAAAAACACCTAGTAAAAAAGTGGTAGTTGTCGGCGGAGGTGTTGGTGGACTTTATGCTGGTTGGCTGGCTGGTTCA
AGAGGACATGATGTGACAGTTTATGAAGCATCTGATATCATTGGCGGTCAAATGCGATTAGCTGCCTATCCTCCGGGAAA
AGGCGACCTGACTAATATGGTTCGTAGTTACATTAAAAAATGCGAACAATTCGACGTAGAAATCAAAACAAACACACCTG
TTACACGCGAGCTTATTCAAAAAGTTTCTCCAGATGCAGTTATTATCGCGACTGGAGCAAACCCACTTATATTGCCAATT
CCTGGTATTGAAGATGCTGGATTGATTCATGCAGTAGACCTACTTGATGGCAAAGAATCTTGTGGCAAAAAAGTTCTCGT
CGTTGGTGGAGGTATGGTTGGTAGTGAAACAGCTGCTTTCTTAGGTGAAGCTGGACACGATGTAACTGTAGTGGAACTTC
GTGAGGAAGTTGGAGCTGATGTCATTTCTGAACACCGCAAATTCCTTATGCGCGATTTTGATGAATATAAAATCAATAGT
ATTACAAATGCAAAAGTGACTAGTTTCTTTGAAGATGGGGTAACTTATTCCTTAGCTGATGATGAAGAATATCGAATTGA
TGGTTTTGATTCTGTGGTACTCGCAATGGGCTCAAGAGCTTATAATCCACTTGAAGAAGCTATTCGGGAATTGGTACCTG
AAACATATGTTATTGGTGATGCCGTTCGCGCACGTCGGGCATTAGACGCAACAAAAGAAGCATTAGACGCTGTATTGCAA
TTATAA

Upstream 100 bases:

>100_bases
TTAGACGAGGCTTGGCCAGAAATTTCTCCAAAATAATGTATTCAAACATGTGAAAATAATAACGTAATCTAGATTCCATC
TTGAAAGGGAAGTGTTTTTT

Downstream 100 bases:

>100_bases
TTCGTGGCTATACTCGCTGTTTCGGCAGCGGGTATAAACCCACTTGGAGGTAAGTGAAACGTGGAAAAAAGAATTTCCGG
CTCAACCCGACTTTTAAGTT

Product: NADH oxidase, putative

Products: trans-transtetradehydroacyl-CoA; NADPH [C]

Alternate protein names: NA

Number of amino acids: Translated: 641; Mature: 641

Protein sequence:

>641_residues
MKFNSMFSPIDIGPMKVPNRFVVSPMCNNYANTDGTLSDTSLAYYKERALGGFGLITFEATVVDVRAKGGANKACLYSDH
QIASFKRVIDVCHDAGAKISVQLQHAGPEGNSKVSGYPLKAASAIASAEGRNTPEAISREELYELIELYGEAALRAKKAG
ADAVEIHCAHGYLVSSFLSGRTNKRVDEFGGCFENRMRLPRLIIESIRKRVGHSIAILCRINSTDGVEGGLSVQDSATVA
AYLEDCGLDGLHVSRSVHIRDEYMWAPTVLHAGFSSDLVTQIKRAVSIPVITVGRFTEPHYAELMVREGRADLVAFGRQS
LADPETPNKAAAGKLDELLPCIACLQGCVANMYAGKPITCLVNPLLGRESEAYLPKTPSKKVVVVGGGVGGLYAGWLAGS
RGHDVTVYEASDIIGGQMRLAAYPPGKGDLTNMVRSYIKKCEQFDVEIKTNTPVTRELIQKVSPDAVIIATGANPLILPI
PGIEDAGLIHAVDLLDGKESCGKKVLVVGGGMVGSETAAFLGEAGHDVTVVELREEVGADVISEHRKFLMRDFDEYKINS
ITNAKVTSFFEDGVTYSLADDEEYRIDGFDSVVLAMGSRAYNPLEEAIRELVPETYVIGDAVRARRALDATKEALDAVLQ
L

Sequences:

>Translated_641_residues
MKFNSMFSPIDIGPMKVPNRFVVSPMCNNYANTDGTLSDTSLAYYKERALGGFGLITFEATVVDVRAKGGANKACLYSDH
QIASFKRVIDVCHDAGAKISVQLQHAGPEGNSKVSGYPLKAASAIASAEGRNTPEAISREELYELIELYGEAALRAKKAG
ADAVEIHCAHGYLVSSFLSGRTNKRVDEFGGCFENRMRLPRLIIESIRKRVGHSIAILCRINSTDGVEGGLSVQDSATVA
AYLEDCGLDGLHVSRSVHIRDEYMWAPTVLHAGFSSDLVTQIKRAVSIPVITVGRFTEPHYAELMVREGRADLVAFGRQS
LADPETPNKAAAGKLDELLPCIACLQGCVANMYAGKPITCLVNPLLGRESEAYLPKTPSKKVVVVGGGVGGLYAGWLAGS
RGHDVTVYEASDIIGGQMRLAAYPPGKGDLTNMVRSYIKKCEQFDVEIKTNTPVTRELIQKVSPDAVIIATGANPLILPI
PGIEDAGLIHAVDLLDGKESCGKKVLVVGGGMVGSETAAFLGEAGHDVTVVELREEVGADVISEHRKFLMRDFDEYKINS
ITNAKVTSFFEDGVTYSLADDEEYRIDGFDSVVLAMGSRAYNPLEEAIRELVPETYVIGDAVRARRALDATKEALDAVLQ
L
>Mature_641_residues
MKFNSMFSPIDIGPMKVPNRFVVSPMCNNYANTDGTLSDTSLAYYKERALGGFGLITFEATVVDVRAKGGANKACLYSDH
QIASFKRVIDVCHDAGAKISVQLQHAGPEGNSKVSGYPLKAASAIASAEGRNTPEAISREELYELIELYGEAALRAKKAG
ADAVEIHCAHGYLVSSFLSGRTNKRVDEFGGCFENRMRLPRLIIESIRKRVGHSIAILCRINSTDGVEGGLSVQDSATVA
AYLEDCGLDGLHVSRSVHIRDEYMWAPTVLHAGFSSDLVTQIKRAVSIPVITVGRFTEPHYAELMVREGRADLVAFGRQS
LADPETPNKAAAGKLDELLPCIACLQGCVANMYAGKPITCLVNPLLGRESEAYLPKTPSKKVVVVGGGVGGLYAGWLAGS
RGHDVTVYEASDIIGGQMRLAAYPPGKGDLTNMVRSYIKKCEQFDVEIKTNTPVTRELIQKVSPDAVIIATGANPLILPI
PGIEDAGLIHAVDLLDGKESCGKKVLVVGGGMVGSETAAFLGEAGHDVTVVELREEVGADVISEHRKFLMRDFDEYKINS
ITNAKVTSFFEDGVTYSLADDEEYRIDGFDSVVLAMGSRAYNPLEEAIRELVPETYVIGDAVRARRALDATKEALDAVLQ
L

Specific function: Catalyzes The NADP-Dependent Reduction Of 2,4-Dienoyl- CoA To Yield Trans-2- Enoyl-CoA. [C]

COG id: COG1902

COG function: function code C; NADH:flavin oxidoreductases, Old Yellow Enzyme family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family [H]

Homologues:

Organism=Escherichia coli, GI1789463, Length=532, Percent_Identity=33.0827067669173, Blast_Score=280, Evalue=2e-76,
Organism=Escherichia coli, GI1787939, Length=347, Percent_Identity=28.8184438040346, Blast_Score=129, Evalue=6e-31,
Organism=Caenorhabditis elegans, GI17559804, Length=337, Percent_Identity=27.5964391691395, Blast_Score=110, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI17564188, Length=315, Percent_Identity=26.984126984127, Blast_Score=105, Evalue=8e-23,
Organism=Caenorhabditis elegans, GI17559802, Length=336, Percent_Identity=27.0833333333333, Blast_Score=102, Evalue=7e-22,
Organism=Caenorhabditis elegans, GI72001454, Length=342, Percent_Identity=26.6081871345029, Blast_Score=96, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI17565138, Length=313, Percent_Identity=25.8785942492013, Blast_Score=96, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI17566914, Length=353, Percent_Identity=26.0623229461756, Blast_Score=94, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17540738, Length=352, Percent_Identity=24.1477272727273, Blast_Score=84, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6325086, Length=367, Percent_Identity=26.158038147139, Blast_Score=115, Evalue=3e-26,
Organism=Saccharomyces cerevisiae, GI6321973, Length=355, Percent_Identity=25.9154929577465, Blast_Score=108, Evalue=2e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR013027
- InterPro:   IPR016040
- InterPro:   IPR001155
- InterPro:   IPR001327 [H]

Pfam domain/function: PF00724 Oxidored_FMN; PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: 1.3.1.34 [C]

Molecular weight: Translated: 69040; Mature: 69040

Theoretical pI: Translated: 5.54; Mature: 5.54

Prosite motif: PS00383 TYR_PHOSPHATASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFNSMFSPIDIGPMKVPNRFVVSPMCNNYANTDGTLSDTSLAYYKERALGGFGLITFEA
CCCCCCCCCCCCCCCCCCCEEEECCHHCCCCCCCCCCCCCHHHHHHHHCCCCEEEEEEEE
TVVDVRAKGGANKACLYSDHQIASFKRVIDVCHDAGAKISVQLQHAGPEGNSKVSGYPLK
EEEEEEECCCCCCEEEECCCHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCCCCCH
AASAIASAEGRNTPEAISREELYELIELYGEAALRAKKAGADAVEIHCAHGYLVSSFLSG
HHHHHHHCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHCC
RTNKRVDEFGGCFENRMRLPRLIIESIRKRVGHSIAILCRINSTDGVEGGLSVQDSATVA
CCCCCHHHHCCHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCCCCCCCHHHH
AYLEDCGLDGLHVSRSVHIRDEYMWAPTVLHAGFSSDLVTQIKRAVSIPVITVGRFTEPH
HHHHHCCCCCEEECEEEEEECCEEECHHHHHCCCCHHHHHHHHHHHCCCEEEECCCCCCH
YAELMVREGRADLVAFGRQSLADPETPNKAAAGKLDELLPCIACLQGCVANMYAGKPITC
HHHHHHHCCCHHHHHHHHHHCCCCCCCCCHHCCCHHHHHHHHHHHHHHHHHHCCCCCHHE
LVNPLLGRESEAYLPKTPSKKVVVVGGGVGGLYAGWLAGSRGHDVTVYEASDIIGGQMRL
EECHHHCCCCCCCCCCCCCCEEEEEECCCHHHHHHHHCCCCCCEEEEEECCCCCCCCEEE
AAYPPGKGDLTNMVRSYIKKCEQFDVEIKTNTPVTRELIQKVSPDAVIIATGANPLILPI
EECCCCCCHHHHHHHHHHHHHHHCCEEEECCCCHHHHHHHHCCCCEEEEEECCCEEEEEC
PGIEDAGLIHAVDLLDGKESCGKKVLVVGGGMVGSETAAFLGEAGHDVTVVELREEVGAD
CCCCCCCCEEEEECCCCHHHCCCEEEEEECCCCCCHHHHHHHCCCCCEEEEEEHHHHCHH
VISEHRKFLMRDFDEYKINSITNAKVTSFFEDGVTYSLADDEEYRIDGFDSVVLAMGSRA
HHHHHHHHHHHCCCHHHCCCCCCCHHHHHHHCCCEEEECCCCCEEECCHHHHHHHHCCCC
YNPLEEAIRELVPETYVIGDAVRARRALDATKEALDAVLQL
CCHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKFNSMFSPIDIGPMKVPNRFVVSPMCNNYANTDGTLSDTSLAYYKERALGGFGLITFEA
CCCCCCCCCCCCCCCCCCCEEEECCHHCCCCCCCCCCCCCHHHHHHHHCCCCEEEEEEEE
TVVDVRAKGGANKACLYSDHQIASFKRVIDVCHDAGAKISVQLQHAGPEGNSKVSGYPLK
EEEEEEECCCCCCEEEECCCHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCCCCCH
AASAIASAEGRNTPEAISREELYELIELYGEAALRAKKAGADAVEIHCAHGYLVSSFLSG
HHHHHHHCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHCC
RTNKRVDEFGGCFENRMRLPRLIIESIRKRVGHSIAILCRINSTDGVEGGLSVQDSATVA
CCCCCHHHHCCHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCCCCCCCCHHHH
AYLEDCGLDGLHVSRSVHIRDEYMWAPTVLHAGFSSDLVTQIKRAVSIPVITVGRFTEPH
HHHHHCCCCCEEECEEEEEECCEEECHHHHHCCCCHHHHHHHHHHHCCCEEEECCCCCCH
YAELMVREGRADLVAFGRQSLADPETPNKAAAGKLDELLPCIACLQGCVANMYAGKPITC
HHHHHHHCCCHHHHHHHHHHCCCCCCCCCHHCCCHHHHHHHHHHHHHHHHHHCCCCCHHE
LVNPLLGRESEAYLPKTPSKKVVVVGGGVGGLYAGWLAGSRGHDVTVYEASDIIGGQMRL
EECHHHCCCCCCCCCCCCCCEEEEEECCCHHHHHHHHCCCCCCEEEEEECCCCCCCCEEE
AAYPPGKGDLTNMVRSYIKKCEQFDVEIKTNTPVTRELIQKVSPDAVIIATGANPLILPI
EECCCCCCHHHHHHHHHHHHHHHCCEEEECCCCHHHHHHHHCCCCEEEEEECCCEEEEEC
PGIEDAGLIHAVDLLDGKESCGKKVLVVGGGMVGSETAAFLGEAGHDVTVVELREEVGAD
CCCCCCCCEEEEECCCCHHHCCCEEEEEECCCCCCHHHHHHHCCCCCEEEEEEHHHHCHH
VISEHRKFLMRDFDEYKINSITNAKVTSFFEDGVTYSLADDEEYRIDGFDSVVLAMGSRA
HHHHHHHHHHHCCCHHHCCCCCCCHHHHHHHCCCEEEECCCCCEEECCHHHHHHHHCCCC
YNPLEEAIRELVPETYVIGDAVRARRALDATKEALDAVLQL
CCHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: FAD. [C]

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: transDidehydroacyl-CoA; NADP+ [C]

Specific reaction: transDidehydroacyl-CoA + NADP+ =trans-transtetradehydroacyl-CoA + NADPH [C]

General reaction: Redox reaction [C]

Inhibitor: Iodoacetic acid; N-Ethyl maleimide [C]

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8491719 [H]