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The map label for this gene is rsbRD [H]

Identifier: 116873277

GI number: 116873277

Start: 1892640

End: 1893461

Strand: Direct

Name: rsbRD [H]

Synonym: lwe1861

Alternate gene names: 116873277

Gene position: 1892640-1893461 (Clockwise)

Preceding gene: 116873276

Following gene: 116873281

Centisome position: 67.25

GC content: 31.63

Gene sequence:

>822_bases
ATGACTATTATGAATCATTTAGTACAACAAAAAGAAATCATCGTGAAAGAGTGGCTTTCATATTATGTATCTGTGGATGA
TCCTTATATTTTTACCCTTAAAAACGATACCCGCCTAAAAGACGAAACAAGACTTGTTTTAGATAATTTATTTATTGGAA
TGAAAGAAGAAAAACAACAAATGAATACTTTTGCTCGTGAACTAGGAAAAGCACAATTTATTACTTCTTTAGGGATATCG
CACATTTTATTTCATATTCGTTTATTAGAGAAATTTATGCTTGAATACGCATTAGAAGTGACTAATACCTCTACAAATTA
CCAAGATTTATATGAATTTAATATGACTCTTCATGAAGTATTTAGTAATTTCACTCAAAATCTAATTGAAGGTTACACCA
TTGCAACAGAAGAATTAATGCAACAAAAAGAAAACCAAATGATTAAGAACTCTACTAAATTAATCCGTATTGCTGAACAA
GTTTTTCTTTTGCCTTTATCAGGAACGATGACCGAAATACGAGCACAGCAAATAATTGAAAGCGCCTTATTTGAAACTTC
CGATCAACCTGTAAGCTACTTAATTATTGATTTATCTGGGATGCAACTTGAATCTCGACATATTGGCGAATATATCAATC
AATTTTTTGAATCATTAAAGTTAGTTGGTGTTACGCCTATTGTTACCGGAATGCAGCCCGAAACTGCAAAAATCATGATC
AATAGCCATATGAAACATCCAAAAGGTATTCAAATTTTCCCCACATTACGTCAGGCAACTAGAGCGCTTATAAAAGAAAA
AGAAGCAAGTAACGAGTTTTAG

Upstream 100 bases:

>100_bases
TTTTAAAAAAGGGATAGCCTTTGGAAATCATTCCTTTTTTAATTATCTTTGTGCTATGATTTAGTTGCTTATAATCAAGT
ACTTAAGAGGTGGAGCTAAA

Downstream 100 bases:

>100_bases
TTTCGTTACTTGCTTCTTTTTTAATCTTCTTGTCGTAATGATTTCAGTGCTTTTTCGAAGGATGCTGGAAGTGGTGCTTC
AAAAGTCATTCGCTCATTTG

Product: STAS domain-containing protein

Products: NA

Alternate protein names: Stressosome protein rsbRD [H]

Number of amino acids: Translated: 273; Mature: 272

Protein sequence:

>273_residues
MTIMNHLVQQKEIIVKEWLSYYVSVDDPYIFTLKNDTRLKDETRLVLDNLFIGMKEEKQQMNTFARELGKAQFITSLGIS
HILFHIRLLEKFMLEYALEVTNTSTNYQDLYEFNMTLHEVFSNFTQNLIEGYTIATEELMQQKENQMIKNSTKLIRIAEQ
VFLLPLSGTMTEIRAQQIIESALFETSDQPVSYLIIDLSGMQLESRHIGEYINQFFESLKLVGVTPIVTGMQPETAKIMI
NSHMKHPKGIQIFPTLRQATRALIKEKEASNEF

Sequences:

>Translated_273_residues
MTIMNHLVQQKEIIVKEWLSYYVSVDDPYIFTLKNDTRLKDETRLVLDNLFIGMKEEKQQMNTFARELGKAQFITSLGIS
HILFHIRLLEKFMLEYALEVTNTSTNYQDLYEFNMTLHEVFSNFTQNLIEGYTIATEELMQQKENQMIKNSTKLIRIAEQ
VFLLPLSGTMTEIRAQQIIESALFETSDQPVSYLIIDLSGMQLESRHIGEYINQFFESLKLVGVTPIVTGMQPETAKIMI
NSHMKHPKGIQIFPTLRQATRALIKEKEASNEF
>Mature_272_residues
TIMNHLVQQKEIIVKEWLSYYVSVDDPYIFTLKNDTRLKDETRLVLDNLFIGMKEEKQQMNTFARELGKAQFITSLGISH
ILFHIRLLEKFMLEYALEVTNTSTNYQDLYEFNMTLHEVFSNFTQNLIEGYTIATEELMQQKENQMIKNSTKLIRIAEQV
FLLPLSGTMTEIRAQQIIESALFETSDQPVSYLIIDLSGMQLESRHIGEYINQFFESLKLVGVTPIVTGMQPETAKIMIN
SHMKHPKGIQIFPTLRQATRALIKEKEASNEF

Specific function: Negative regulator of sigma-B activity. Non- phosphorylated rsbS binds to rsbT, preventing its association with rsbU. Requires any one of rsbRA, rsbRB, rsbRC or rsbRD to sequester rsbT. When rsbS and the rsbR paralog(s) are phosphorylated, they release rs

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 STAS domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002645 [H]

Pfam domain/function: PF01740 STAS [H]

EC number: NA

Molecular weight: Translated: 31730; Mature: 31599

Theoretical pI: Translated: 5.40; Mature: 5.40

Prosite motif: PS50801 STAS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIMNHLVQQKEIIVKEWLSYYVSVDDPYIFTLKNDTRLKDETRLVLDNLFIGMKEEKQQ
CCHHHHHHHHHHHHHHHHHHHHEECCCCEEEEECCCCCCCHHHHHHHHHHHCCCHHHHHH
MNTFARELGKAQFITSLGISHILFHIRLLEKFMLEYALEVTNTSTNYQDLYEFNMTLHEV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
FSNFTQNLIEGYTIATEELMQQKENQMIKNSTKLIRIAEQVFLLPLSGTMTEIRAQQIIE
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCHHHHHHHHHHHH
SALFETSDQPVSYLIIDLSGMQLESRHIGEYINQFFESLKLVGVTPIVTGMQPETAKIMI
HHHHCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCHHHEEE
NSHMKHPKGIQIFPTLRQATRALIKEKEASNEF
CCCCCCCCCCEEHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TIMNHLVQQKEIIVKEWLSYYVSVDDPYIFTLKNDTRLKDETRLVLDNLFIGMKEEKQQ
CHHHHHHHHHHHHHHHHHHHHEECCCCEEEEECCCCCCCHHHHHHHHHHHCCCHHHHHH
MNTFARELGKAQFITSLGISHILFHIRLLEKFMLEYALEVTNTSTNYQDLYEFNMTLHEV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
FSNFTQNLIEGYTIATEELMQQKENQMIKNSTKLIRIAEQVFLLPLSGTMTEIRAQQIIE
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCHHHHHHHHHHHH
SALFETSDQPVSYLIIDLSGMQLESRHIGEYINQFFESLKLVGVTPIVTGMQPETAKIMI
HHHHCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCHHHEEE
NSHMKHPKGIQIFPTLRQATRALIKEKEASNEF
CCCCCCCCCCEEHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377; 11157946 [H]