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The map label for this gene is insK [H]

Identifier: 116873032

GI number: 116873032

Start: 1623321

End: 1624130

Strand: Direct

Name: insK [H]

Synonym: lwe1616

Alternate gene names: 116873032

Gene position: 1623321-1624130 (Clockwise)

Preceding gene: 116873031

Following gene: 116873035

Centisome position: 57.68

GC content: 33.83

Gene sequence:

>810_bases
ATGTATTGGCAAAAGCATTTGAATAGAGAAAATCCGACAGAAGAAGTAGAGAATGAATTAAAAGCTATTCGTCAAGCACA
TCCTAATTATGGCTATAGACGAATGACACAAGAACTGAAACGTCGCGGCTTCCAAATAAATAAAAAGAAAGTGCAACGCT
TAATTCAAAAATTGAGATTACAAGTCCAATCATTCACCCGTAAATCTCGAAAGTATAACTCCTATAGAGGAAATGTAGGG
AAAACGGCTAAAAATCTCGTAAAAAGACACTTTTATACTGCTATACCTCATCAAAAGATAACCACAGATACGACAGAGTT
TAAATATGTTGAAACAGATTCATCTGGTATACTTCGGCAGAAGAAAATGTATCTAAATCCATTTATGGATTTGTATAACA
GCGAAATTATTAGCTATACTATCTCTGAACGCCCTACTGCTCAAGCAATTATGACTGGCCTGGAAGAGTCCATAAAGCAA
ACGAGTGACTGTCCTTACCGCCGAACTTTTCATTCAGATCAAGGTTGGGCTTATCAAATGACTGCTTATAGTTCCGCCTT
AAAAAAACATCGTATTTTTCAAAGTATGTCTCGAAAAGGAAATTGTTTAGATAATTCTCCCATGGAGAATTTCTTCGGTC
TTCTCAAGCAAGAAATATATTATGGCAAGATTTATTCTAATTACCATGAGCTGAAGCAAGCTATTAAAAATTATATTCAC
TATTATAATCAATATCGTATGAAAGAAAAACTTCATTGGCAAAGCCCTATTGAATTTCGAAAAAATCAATTATTAATAGC
ACAAAAATAG

Upstream 100 bases:

>100_bases
AACGCAAAATGAGCGAATTGCACGAGTCATTCACAGCCTCCGAAGACGCTTCCGATTAACTGAAATCTTAGAAACCCTTC
GGTTTCCTAAATCTACCTAT

Downstream 100 bases:

>100_bases
AGTGGAAAAAATCCACTCTACAAATTGTCCAACTTTTGGGGGTCACTACATTTTCCAATTAATATTATTTTACTTCTTTT
TTAGCATCAACAGCAATTTT

Product: transposase, putative

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 269; Mature: 269

Protein sequence:

>269_residues
MYWQKHLNRENPTEEVENELKAIRQAHPNYGYRRMTQELKRRGFQINKKKVQRLIQKLRLQVQSFTRKSRKYNSYRGNVG
KTAKNLVKRHFYTAIPHQKITTDTTEFKYVETDSSGILRQKKMYLNPFMDLYNSEIISYTISERPTAQAIMTGLEESIKQ
TSDCPYRRTFHSDQGWAYQMTAYSSALKKHRIFQSMSRKGNCLDNSPMENFFGLLKQEIYYGKIYSNYHELKQAIKNYIH
YYNQYRMKEKLHWQSPIEFRKNQLLIAQK

Sequences:

>Translated_269_residues
MYWQKHLNRENPTEEVENELKAIRQAHPNYGYRRMTQELKRRGFQINKKKVQRLIQKLRLQVQSFTRKSRKYNSYRGNVG
KTAKNLVKRHFYTAIPHQKITTDTTEFKYVETDSSGILRQKKMYLNPFMDLYNSEIISYTISERPTAQAIMTGLEESIKQ
TSDCPYRRTFHSDQGWAYQMTAYSSALKKHRIFQSMSRKGNCLDNSPMENFFGLLKQEIYYGKIYSNYHELKQAIKNYIH
YYNQYRMKEKLHWQSPIEFRKNQLLIAQK
>Mature_269_residues
MYWQKHLNRENPTEEVENELKAIRQAHPNYGYRRMTQELKRRGFQINKKKVQRLIQKLRLQVQSFTRKSRKYNSYRGNVG
KTAKNLVKRHFYTAIPHQKITTDTTEFKYVETDSSGILRQKKMYLNPFMDLYNSEIISYTISERPTAQAIMTGLEESIKQ
TSDCPYRRTFHSDQGWAYQMTAYSSALKKHRIFQSMSRKGNCLDNSPMENFFGLLKQEIYYGKIYSNYHELKQAIKNYIH
YYNQYRMKEKLHWQSPIEFRKNQLLIAQK

Specific function: Involved in the transposition of the insertion sequence IS150 [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 integrase catalytic domain [H]

Homologues:

Organism=Homo sapiens, GI310129419, Length=196, Percent_Identity=28.5714285714286, Blast_Score=80, Evalue=1e-15,
Organism=Escherichia coli, GI1789981, Length=232, Percent_Identity=46.551724137931, Blast_Score=202, Evalue=1e-53,
Organism=Escherichia coli, GI1788405, Length=248, Percent_Identity=30.6451612903226, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1787263, Length=248, Percent_Identity=30.6451612903226, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1786753, Length=248, Percent_Identity=30.6451612903226, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1786570, Length=248, Percent_Identity=30.6451612903226, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1786490, Length=248, Percent_Identity=30.6451612903226, Blast_Score=112, Evalue=3e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001584
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00665 rve [H]

EC number: NA

Molecular weight: Translated: 32422; Mature: 32422

Theoretical pI: Translated: 10.40; Mature: 10.40

Prosite motif: PS50994 INTEGRASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYWQKHLNRENPTEEVENELKAIRQAHPNYGYRRMTQELKRRGFQINKKKVQRLIQKLRL
CCCHHHCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
QVQSFTRKSRKYNSYRGNVGKTAKNLVKRHFYTAIPHQKITTDTTEFKYVETDSSGILRQ
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCHHHH
KKMYLNPFMDLYNSEIISYTISERPTAQAIMTGLEESIKQTSDCPYRRTFHSDQGWAYQM
HHHHHHHHHHHHCCHHHEEECCCCCHHHHHHHHHHHHHHHHCCCCCHHCCCCCCCCEEHH
TAYSSALKKHRIFQSMSRKGNCLDNSPMENFFGLLKQEIYYGKIYSNYHELKQAIKNYIH
HHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YYNQYRMKEKLHWQSPIEFRKNQLLIAQK
HHHHHHHHHHHCCCCCHHHCCCCEEEECC
>Mature Secondary Structure
MYWQKHLNRENPTEEVENELKAIRQAHPNYGYRRMTQELKRRGFQINKKKVQRLIQKLRL
CCCHHHCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
QVQSFTRKSRKYNSYRGNVGKTAKNLVKRHFYTAIPHQKITTDTTEFKYVETDSSGILRQ
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCCCHHHH
KKMYLNPFMDLYNSEIISYTISERPTAQAIMTGLEESIKQTSDCPYRRTFHSDQGWAYQM
HHHHHHHHHHHHCCHHHEEECCCCCHHHHHHHHHHHHHHHHCCCCCHHCCCCCCCCEEHH
TAYSSALKKHRIFQSMSRKGNCLDNSPMENFFGLLKQEIYYGKIYSNYHELKQAIKNYIH
HHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YYNQYRMKEKLHWQSPIEFRKNQLLIAQK
HHHHHHHHHHHCCCCCHHHCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2841644; 2541046; 8041620; 9278503 [H]