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The map label for this gene is ykvY [H]

Identifier: 116873007

GI number: 116873007

Start: 1597532

End: 1598629

Strand: Direct

Name: ykvY [H]

Synonym: lwe1591

Alternate gene names: 116873007

Gene position: 1597532-1598629 (Clockwise)

Preceding gene: 116872950

Following gene: 116873009

Centisome position: 56.77

GC content: 38.25

Gene sequence:

>1098_bases
ATGGAAAAAAATATCGATGTCTTACAAAATTGGTTAAAAGACCAAGGTGCCGAGGTTGCATTTTTGACAGATCCAGAGAA
TATCGCTTACTTCTCAGGTTATCATAGCGAGCCTCATGAACGTGTACTTGGTTTAGCCGTATTCCCTGAAAGTGAACCGT
TTTTATTTACGCCAGCATTAGAGGTAGAAGATTTGCGTGGCGGCGATTGGACACATCCTGCATATGGATATAACGATACA
GAAAATCCGTTCACCATCATTGCAGATGAAATCAAAAAACGTGTAGCAAATCCAACTAAATTTGCTATTGAAAAAAAACA
TATGAGTGTAGACCGTTTTGAACAATTAAGCGGACTCTTCTCGGGTTGCTCTTTTATTCCGATTGAACACAAGATTGAAC
AAGTTCGTCTTATTAAAACAGAAGCAGAACTGAAGATTTTAAAAGAAGCTGCTTTACTTGCTGATTACGCAGTACAAGTA
GGTGTAGACGAAATCGCAGAAGGTAAAACAGAAGCAGAAATCGTTGCAAAAATCGAATATGAAATGAAGAAAAAAGGCGT
AACGGCGATGTCTTTCGATACGATGGTACTAACTGGAAAAAATGGCGCCTTGCCTCATGGGACACCTGGTGAAACAAAAA
TCAAAAAAGGCGATTTAGTTTTATTTGATTTAGGTGTTGTTCACAAAGGCTATTGCTCTGATATTACACGTACAGTTGCT
TTTGGTGATATTTCTGATGAACAGAAAAAAATTTATGACACTGTTTTAGAAGCACAAGTTTCTGCAGTGGAAAAAGTAAA
AGCTGGAGTGAAAGCAAGCGAAATCGACTTAACTGCTAGAAATATTATTCGTGAAGCTGGATACGGCGATTATTTCCCAC
ATCGTCTTGGTCATGGACTTGGCGCGAGTGTGCATGAATTCCCTTCTATTACGGAAACAAACAATATGGAGTTACAAGAA
AATATGGTATTTACTATTGAGCCTGGTATTTATGTTCCAGGTGTTGCTGGTGTGCGTATTGAAGATGACCTCGTTGTCAC
AAAAGATGGTGTACAAGTACTGACAGAGTTTCCGAAAACATTACAAGTAATCAAATAA

Upstream 100 bases:

>100_bases
CTAATATATAACACCTCGTAAACTATGAGGTGTTTATTAGCAAAATATTTCCATCACATGTTATCATGATAGTGAAATCA
ATTGGAAAGAAGGTACAATA

Downstream 100 bases:

>100_bases
TAAAACAGCGAACTTCCTCTGGGAAGTTCGCTGTTTTATTAAAGTAATTCTTTACTATCTGTATAAACTAATCCAAGTGA
GTCAGCAACAGCTTTATAAG

Product: metallopeptidase protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 365; Mature: 365

Protein sequence:

>365_residues
MEKNIDVLQNWLKDQGAEVAFLTDPENIAYFSGYHSEPHERVLGLAVFPESEPFLFTPALEVEDLRGGDWTHPAYGYNDT
ENPFTIIADEIKKRVANPTKFAIEKKHMSVDRFEQLSGLFSGCSFIPIEHKIEQVRLIKTEAELKILKEAALLADYAVQV
GVDEIAEGKTEAEIVAKIEYEMKKKGVTAMSFDTMVLTGKNGALPHGTPGETKIKKGDLVLFDLGVVHKGYCSDITRTVA
FGDISDEQKKIYDTVLEAQVSAVEKVKAGVKASEIDLTARNIIREAGYGDYFPHRLGHGLGASVHEFPSITETNNMELQE
NMVFTIEPGIYVPGVAGVRIEDDLVVTKDGVQVLTEFPKTLQVIK

Sequences:

>Translated_365_residues
MEKNIDVLQNWLKDQGAEVAFLTDPENIAYFSGYHSEPHERVLGLAVFPESEPFLFTPALEVEDLRGGDWTHPAYGYNDT
ENPFTIIADEIKKRVANPTKFAIEKKHMSVDRFEQLSGLFSGCSFIPIEHKIEQVRLIKTEAELKILKEAALLADYAVQV
GVDEIAEGKTEAEIVAKIEYEMKKKGVTAMSFDTMVLTGKNGALPHGTPGETKIKKGDLVLFDLGVVHKGYCSDITRTVA
FGDISDEQKKIYDTVLEAQVSAVEKVKAGVKASEIDLTARNIIREAGYGDYFPHRLGHGLGASVHEFPSITETNNMELQE
NMVFTIEPGIYVPGVAGVRIEDDLVVTKDGVQVLTEFPKTLQVIK
>Mature_365_residues
MEKNIDVLQNWLKDQGAEVAFLTDPENIAYFSGYHSEPHERVLGLAVFPESEPFLFTPALEVEDLRGGDWTHPAYGYNDT
ENPFTIIADEIKKRVANPTKFAIEKKHMSVDRFEQLSGLFSGCSFIPIEHKIEQVRLIKTEAELKILKEAALLADYAVQV
GVDEIAEGKTEAEIVAKIEYEMKKKGVTAMSFDTMVLTGKNGALPHGTPGETKIKKGDLVLFDLGVVHKGYCSDITRTVA
FGDISDEQKKIYDTVLEAQVSAVEKVKAGVKASEIDLTARNIIREAGYGDYFPHRLGHGLGASVHEFPSITETNNMELQE
NMVFTIEPGIYVPGVAGVRIEDDLVVTKDGVQVLTEFPKTLQVIK

Specific function: Unknown

COG id: COG0006

COG function: function code E; Xaa-Pro aminopeptidase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24B family [H]

Homologues:

Organism=Homo sapiens, GI11559925, Length=268, Percent_Identity=31.7164179104478, Blast_Score=112, Evalue=7e-25,
Organism=Homo sapiens, GI149589008, Length=298, Percent_Identity=28.1879194630872, Blast_Score=102, Evalue=6e-22,
Organism=Homo sapiens, GI260593665, Length=298, Percent_Identity=28.1879194630872, Blast_Score=102, Evalue=7e-22,
Organism=Homo sapiens, GI260593663, Length=249, Percent_Identity=28.9156626506024, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI40385867, Length=246, Percent_Identity=25.609756097561, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI93141226, Length=193, Percent_Identity=32.6424870466321, Blast_Score=86, Evalue=6e-17,
Organism=Homo sapiens, GI264681563, Length=177, Percent_Identity=31.638418079096, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI164420681, Length=243, Percent_Identity=26.3374485596708, Blast_Score=73, Evalue=4e-13,
Organism=Homo sapiens, GI264681565, Length=174, Percent_Identity=30.4597701149425, Blast_Score=68, Evalue=1e-11,
Organism=Escherichia coli, GI1788728, Length=370, Percent_Identity=34.0540540540541, Blast_Score=192, Evalue=4e-50,
Organism=Escherichia coli, GI1789275, Length=256, Percent_Identity=30.078125, Blast_Score=120, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI17508215, Length=299, Percent_Identity=25.4180602006689, Blast_Score=104, Evalue=8e-23,
Organism=Caenorhabditis elegans, GI71989583, Length=258, Percent_Identity=25.968992248062, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17509539, Length=211, Percent_Identity=31.7535545023697, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI71996291, Length=249, Percent_Identity=28.5140562248996, Blast_Score=73, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6321118, Length=295, Percent_Identity=26.4406779661017, Blast_Score=101, Evalue=2e-22,
Organism=Saccharomyces cerevisiae, GI6320922, Length=253, Percent_Identity=26.8774703557312, Blast_Score=100, Evalue=3e-22,
Organism=Saccharomyces cerevisiae, GI6322999, Length=246, Percent_Identity=27.2357723577236, Blast_Score=67, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6323273, Length=233, Percent_Identity=25.7510729613734, Blast_Score=67, Evalue=4e-12,
Organism=Drosophila melanogaster, GI19920384, Length=277, Percent_Identity=29.9638989169675, Blast_Score=115, Evalue=5e-26,
Organism=Drosophila melanogaster, GI21357079, Length=298, Percent_Identity=27.8523489932886, Blast_Score=95, Evalue=9e-20,
Organism=Drosophila melanogaster, GI21355531, Length=232, Percent_Identity=27.1551724137931, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI17137632, Length=241, Percent_Identity=28.6307053941909, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI161078230, Length=196, Percent_Identity=29.0816326530612, Blast_Score=65, Evalue=7e-11,
Organism=Drosophila melanogaster, GI21357287, Length=196, Percent_Identity=29.0816326530612, Blast_Score=65, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000587
- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR001131 [H]

Pfam domain/function: PF01321 Creatinase_N; PF00557 Peptidase_M24 [H]

EC number: 3.4.-.- [C]

Molecular weight: Translated: 40434; Mature: 40434

Theoretical pI: Translated: 4.72; Mature: 4.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKNIDVLQNWLKDQGAEVAFLTDPENIAYFSGYHSEPHERVLGLAVFPESEPFLFTPAL
CCCCHHHHHHHHHCCCCEEEEEECCCCEEEECCCCCCHHHHEEEEEECCCCCCEEEECCC
EVEDLRGGDWTHPAYGYNDTENPFTIIADEIKKRVANPTKFAIEKKHMSVDRFEQLSGLF
CCCCCCCCCCCCCCCCCCCCCCCCEEEHHHHHHHHCCCHHEEEEHHHCCHHHHHHHHHHH
SGCSFIPIEHKIEQVRLIKTEAELKILKEAALLADYAVQVGVDEIAEGKTEAEIVAKIEY
CCCCCCCHHHHHHHEEEEHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCHHEEEHHHH
EMKKKGVTAMSFDTMVLTGKNGALPHGTPGETKIKKGDLVLFDLGVVHKGYCSDITRTVA
HHHHCCCEEEEECEEEEECCCCCCCCCCCCCCEEECCCEEEEECCCCCCCHHHHHHHHEE
FGDISDEQKKIYDTVLEAQVSAVEKVKAGVKASEIDLTARNIIREAGYGDYFPHRLGHGL
ECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCHHHHCCCC
GASVHEFPSITETNNMELQENMVFTIEPGIYVPGVAGVRIEDDLVVTKDGVQVLTEFPKT
CCCHHHCCCCCCCCCCEEECCEEEEECCCEECCCCCCEEEECCEEEECCHHHHHHHHHHH
LQVIK
HHHCC
>Mature Secondary Structure
MEKNIDVLQNWLKDQGAEVAFLTDPENIAYFSGYHSEPHERVLGLAVFPESEPFLFTPAL
CCCCHHHHHHHHHCCCCEEEEEECCCCEEEECCCCCCHHHHEEEEEECCCCCCEEEECCC
EVEDLRGGDWTHPAYGYNDTENPFTIIADEIKKRVANPTKFAIEKKHMSVDRFEQLSGLF
CCCCCCCCCCCCCCCCCCCCCCCCEEEHHHHHHHHCCCHHEEEEHHHCCHHHHHHHHHHH
SGCSFIPIEHKIEQVRLIKTEAELKILKEAALLADYAVQVGVDEIAEGKTEAEIVAKIEY
CCCCCCCHHHHHHHEEEEHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCHHEEEHHHH
EMKKKGVTAMSFDTMVLTGKNGALPHGTPGETKIKKGDLVLFDLGVVHKGYCSDITRTVA
HHHHCCCEEEEECEEEEECCCCCCCCCCCCCCEEECCCEEEEECCCCCCCHHHHHHHHEE
FGDISDEQKKIYDTVLEAQVSAVEKVKAGVKASEIDLTARNIIREAGYGDYFPHRLGHGL
ECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCHHHHCCCC
GASVHEFPSITETNNMELQENMVFTIEPGIYVPGVAGVRIEDDLVVTKDGVQVLTEFPKT
CCCHHHCCCCCCCCCCEEECCEEEEECCCEECCCCCCEEEECCEEEECCHHHHHHHHHHH
LQVIK
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]