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The map label for this gene is ykpA [H]

Identifier: 116872864

GI number: 116872864

Start: 1442883

End: 1444484

Strand: Direct

Name: ykpA [H]

Synonym: lwe1448

Alternate gene names: 116872864

Gene position: 1442883-1444484 (Clockwise)

Preceding gene: 116872855

Following gene: 116872873

Centisome position: 51.27

GC content: 35.71

Gene sequence:

>1602_bases
ATGTTAACTGTAAATAATGTTGGCTTACGCTACGGCGATAAAAAGCTATTTGAAGATGTTTCGATTAAATTTTTACCAGG
GAACTGTTATGGGCTTATTGGAGCAAACGGTGCTGGTAAATCAACGTTCCTAAAAGTGCTTTCTGGCGAGCTTGATTCAC
AAAGTGGTAATGTGCATATTGGTTCAGGTGAGCGTCTAGCTGTCCTTCGCCAAGATCATTTCCAGTATGATGATGAACTC
GTACTCAACACGGTAATTATGGGACATGAACGTCTATATAAAATTATGGACGAAAAAAATGCCATTTATATGAAAGAAGA
TTTTAGTGATGCAGATGGTATTCGTGCTGCCGAACTAGAAGGTGAATTTGCTGAATTAGATGGTTGGGAAGCAGAATCAG
ACGCTGCTGTTTTATTAAACGGTTTAGGTATCCCTACTGACTTGCACGGAAAACTAATGAAAGATTTAACTGGTGGAGAA
AAAGTAAAAGTGCTACTTGCGCAAGCTTTATTCGGTAAACCAGATATCTTACTTCTGGATGAGCCTACTAACCACCTTGA
CATTCGTGCCATTCATTGGTTAGAAGAATTTTTAATTAACTTTGATAATACTGTTATCGTTGTATCCCATGATCGTCATT
TCTTGAATAAAGTATGTACTCATATTGCGGATCTTGATTTTAGTAAAATTAAATTATATGTTGGTAACTATGATTTCTGG
TATGAATCTAGTCAATTAGCTCAAACAATGATGGGCGATCGTAATAAGAAAAAAGAAGAAAAAATGAAAGAACTACAAGA
CTTTATTGCCAGATTTAGTGCGAACGCATCAAAATCTAAACAAGCAACAAGTCGTAAAAAAATGCTCGAAAAAATCACAC
TGGAAGATATTCAACCTTCTAGTCGTCGTTACCCTTTTATTCAGTTTAAACCGGATCGTGAAGTTGGGAATGACCTTCTG
ACAGTGACCAATTTGTCAAAAACAATTGATGGCGTGAAGATACTTGATAATCTTTCTTTCTCTATTAATCGTAATGACAA
AGTTGCTTTAGTTGGCGATGATGAAGTTGCTAAAACAGTTCTTTTCCAAATTTTGGCTGGTGAAATGGAACCTGATGAAG
GTAGTTATAAATGGGGTATCACAACAAGCCAAAGTTATTTCCCTAAAGATAACTCAGAATTCTTTGAGGAAAACGACATG
AGTCTTGTAGAATGGTTACGTCAATTCTCTCCAGAAGATGATAGTGAAGCATTCTTACGCGGATTCCTTGGCCGTATGCT
ATTCAGTGGTGATGAAGTACTTAAAAAAGTACGCGTCCTATCTGGTGGAGAGAAAGTTCGTTGTATGTTATCAAAAATGA
TGCTTTCTGGTTCTAACGTCCTTTTACTAGATGAACCTACTAACCACTTGGATTTAGAGTCTATCACAGCCTTAAATAAC
GGTCTTGAATCATTTAAAGGTGCCATGATTTTTGCTTCTCATGACCATCAGTTACTACAAACAATTGCAACTCGTATTAT
TAACTTATCTAAAGATCAATTTTATAATAAAGAAATTTCTTATGATGAATATCTAAAAGAAGTTATGAATGTTGCTGAAT
AA

Upstream 100 bases:

>100_bases
ATGCGTGTATGCTTTCTTTGCTACACTAACCATGTTAAAATAGTAGTAATTGTGCTTTTTCTGATTTCAAGAAGAAGTAA
CTTAGTATTGGAGGAAGAAA

Downstream 100 bases:

>100_bases
GCAAAAAAACAATATCCCATTAGCGGGATATTGTTTTTTTATTTAAGTTCGATTTTGCCTGTTTCAGTTGTGATTGGTGT
GGAAGAATCTGTTAAATAAC

Product: ABC transporter ATP-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 533; Mature: 533

Protein sequence:

>533_residues
MLTVNNVGLRYGDKKLFEDVSIKFLPGNCYGLIGANGAGKSTFLKVLSGELDSQSGNVHIGSGERLAVLRQDHFQYDDEL
VLNTVIMGHERLYKIMDEKNAIYMKEDFSDADGIRAAELEGEFAELDGWEAESDAAVLLNGLGIPTDLHGKLMKDLTGGE
KVKVLLAQALFGKPDILLLDEPTNHLDIRAIHWLEEFLINFDNTVIVVSHDRHFLNKVCTHIADLDFSKIKLYVGNYDFW
YESSQLAQTMMGDRNKKKEEKMKELQDFIARFSANASKSKQATSRKKMLEKITLEDIQPSSRRYPFIQFKPDREVGNDLL
TVTNLSKTIDGVKILDNLSFSINRNDKVALVGDDEVAKTVLFQILAGEMEPDEGSYKWGITTSQSYFPKDNSEFFEENDM
SLVEWLRQFSPEDDSEAFLRGFLGRMLFSGDEVLKKVRVLSGGEKVRCMLSKMMLSGSNVLLLDEPTNHLDLESITALNN
GLESFKGAMIFASHDHQLLQTIATRIINLSKDQFYNKEISYDEYLKEVMNVAE

Sequences:

>Translated_533_residues
MLTVNNVGLRYGDKKLFEDVSIKFLPGNCYGLIGANGAGKSTFLKVLSGELDSQSGNVHIGSGERLAVLRQDHFQYDDEL
VLNTVIMGHERLYKIMDEKNAIYMKEDFSDADGIRAAELEGEFAELDGWEAESDAAVLLNGLGIPTDLHGKLMKDLTGGE
KVKVLLAQALFGKPDILLLDEPTNHLDIRAIHWLEEFLINFDNTVIVVSHDRHFLNKVCTHIADLDFSKIKLYVGNYDFW
YESSQLAQTMMGDRNKKKEEKMKELQDFIARFSANASKSKQATSRKKMLEKITLEDIQPSSRRYPFIQFKPDREVGNDLL
TVTNLSKTIDGVKILDNLSFSINRNDKVALVGDDEVAKTVLFQILAGEMEPDEGSYKWGITTSQSYFPKDNSEFFEENDM
SLVEWLRQFSPEDDSEAFLRGFLGRMLFSGDEVLKKVRVLSGGEKVRCMLSKMMLSGSNVLLLDEPTNHLDLESITALNN
GLESFKGAMIFASHDHQLLQTIATRIINLSKDQFYNKEISYDEYLKEVMNVAE
>Mature_533_residues
MLTVNNVGLRYGDKKLFEDVSIKFLPGNCYGLIGANGAGKSTFLKVLSGELDSQSGNVHIGSGERLAVLRQDHFQYDDEL
VLNTVIMGHERLYKIMDEKNAIYMKEDFSDADGIRAAELEGEFAELDGWEAESDAAVLLNGLGIPTDLHGKLMKDLTGGE
KVKVLLAQALFGKPDILLLDEPTNHLDIRAIHWLEEFLINFDNTVIVVSHDRHFLNKVCTHIADLDFSKIKLYVGNYDFW
YESSQLAQTMMGDRNKKKEEKMKELQDFIARFSANASKSKQATSRKKMLEKITLEDIQPSSRRYPFIQFKPDREVGNDLL
TVTNLSKTIDGVKILDNLSFSINRNDKVALVGDDEVAKTVLFQILAGEMEPDEGSYKWGITTSQSYFPKDNSEFFEENDM
SLVEWLRQFSPEDDSEAFLRGFLGRMLFSGDEVLKKVRVLSGGEKVRCMLSKMMLSGSNVLLLDEPTNHLDLESITALNN
GLESFKGAMIFASHDHQLLQTIATRIINLSKDQFYNKEISYDEYLKEVMNVAE

Specific function: Unknown

COG id: COG0488

COG function: function code R; ATPase components of ABC transporters with duplicated ATPase domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ABC transporter domains [H]

Homologues:

Organism=Homo sapiens, GI148612853, Length=529, Percent_Identity=30.0567107750473, Blast_Score=248, Evalue=1e-65,
Organism=Homo sapiens, GI27881506, Length=533, Percent_Identity=33.0206378986867, Blast_Score=246, Evalue=6e-65,
Organism=Homo sapiens, GI10947137, Length=533, Percent_Identity=33.0206378986867, Blast_Score=245, Evalue=6e-65,
Organism=Homo sapiens, GI69354671, Length=546, Percent_Identity=27.8388278388278, Blast_Score=182, Evalue=5e-46,
Organism=Homo sapiens, GI10947135, Length=546, Percent_Identity=27.8388278388278, Blast_Score=182, Evalue=5e-46,
Organism=Homo sapiens, GI105990541, Length=207, Percent_Identity=28.5024154589372, Blast_Score=77, Evalue=4e-14,
Organism=Escherichia coli, GI1787041, Length=526, Percent_Identity=45.8174904942966, Blast_Score=508, Evalue=1e-145,
Organism=Escherichia coli, GI1789751, Length=504, Percent_Identity=34.1269841269841, Blast_Score=279, Evalue=4e-76,
Organism=Escherichia coli, GI2367384, Length=555, Percent_Identity=32.0720720720721, Blast_Score=239, Evalue=4e-64,
Organism=Escherichia coli, GI1787182, Length=509, Percent_Identity=27.7013752455796, Blast_Score=202, Evalue=3e-53,
Organism=Escherichia coli, GI1786398, Length=211, Percent_Identity=25.5924170616114, Blast_Score=66, Evalue=5e-12,
Organism=Escherichia coli, GI1787029, Length=233, Percent_Identity=24.0343347639485, Blast_Score=65, Evalue=8e-12,
Organism=Escherichia coli, GI87081709, Length=257, Percent_Identity=24.5136186770428, Blast_Score=65, Evalue=2e-11,
Organism=Escherichia coli, GI1786703, Length=196, Percent_Identity=31.1224489795918, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1788644, Length=236, Percent_Identity=27.1186440677966, Blast_Score=62, Evalue=9e-11,
Organism=Caenorhabditis elegans, GI17553372, Length=539, Percent_Identity=32.2820037105751, Blast_Score=251, Evalue=8e-67,
Organism=Caenorhabditis elegans, GI17555318, Length=513, Percent_Identity=29.4346978557505, Blast_Score=215, Evalue=4e-56,
Organism=Caenorhabditis elegans, GI17559834, Length=553, Percent_Identity=27.124773960217, Blast_Score=207, Evalue=2e-53,
Organism=Caenorhabditis elegans, GI17565586, Length=236, Percent_Identity=26.271186440678, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17558664, Length=216, Percent_Identity=29.1666666666667, Blast_Score=69, Evalue=5e-12,
Organism=Saccharomyces cerevisiae, GI6320874, Length=527, Percent_Identity=33.5863377609108, Blast_Score=244, Evalue=2e-65,
Organism=Saccharomyces cerevisiae, GI6321121, Length=531, Percent_Identity=27.8719397363465, Blast_Score=210, Evalue=4e-55,
Organism=Saccharomyces cerevisiae, GI6325030, Length=420, Percent_Identity=27.1428571428571, Blast_Score=123, Evalue=6e-29,
Organism=Saccharomyces cerevisiae, GI6324314, Length=367, Percent_Identity=26.7029972752044, Blast_Score=97, Evalue=7e-21,
Organism=Saccharomyces cerevisiae, GI6323278, Length=367, Percent_Identity=24.2506811989101, Blast_Score=95, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24666836, Length=540, Percent_Identity=30.5555555555556, Blast_Score=249, Evalue=4e-66,
Organism=Drosophila melanogaster, GI24642252, Length=520, Percent_Identity=30.1923076923077, Blast_Score=224, Evalue=1e-58,
Organism=Drosophila melanogaster, GI18859989, Length=520, Percent_Identity=30.1923076923077, Blast_Score=224, Evalue=1e-58,
Organism=Drosophila melanogaster, GI24641342, Length=546, Percent_Identity=29.6703296703297, Blast_Score=219, Evalue=5e-57,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 60275; Mature: 60275

Theoretical pI: Translated: 4.75; Mature: 4.75

Prosite motif: PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTVNNVGLRYGDKKLFEDVSIKFLPGNCYGLIGANGAGKSTFLKVLSGELDSQSGNVHI
CEEECCCCCCCCCHHHHCCCEEEEECCCEEEEEECCCCCHHHHHHHHHCCCCCCCCCEEE
GSGERLAVLRQDHFQYDDELVLNTVIMGHERLYKIMDEKNAIYMKEDFSDADGIRAAELE
CCCCEEEEEEHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCEEEECC
GEFAELDGWEAESDAAVLLNGLGIPTDLHGKLMKDLTGGEKVKVLLAQALFGKPDILLLD
CCHHHCCCCCCCCCCEEEEECCCCCCCHHHHHHHHCCCCHHHHHHHHHHHCCCCCEEEEE
EPTNHLDIRAIHWLEEFLINFDNTVIVVSHDRHFLNKVCTHIADLDFSKIKLYVGNYDFW
CCCCCCCHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHCCCCEEEEEEECCEEEE
YESSQLAQTMMGDRNKKKEEKMKELQDFIARFSANASKSKQATSRKKMLEKITLEDIQPS
ECHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCC
SRRYPFIQFKPDREVGNDLLTVTNLSKTIDGVKILDNLSFSINRNDKVALVGDDEVAKTV
CCCCCEEEECCCHHHCCCEEEEEHHHHHHCCHHHHHCCEEEECCCCEEEEECCHHHHHHH
LFQILAGEMEPDEGSYKWGITTSQSYFPKDNSEFFEENDMSLVEWLRQFSPEDDSEAFLR
HHHHHHCCCCCCCCCEEECCCCCCCCCCCCCCHHHHCCCHHHHHHHHHCCCCCCHHHHHH
GFLGRMLFSGDEVLKKVRVLSGGEKVRCMLSKMMLSGSNVLLLDEPTNHLDLESITALNN
HHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHH
GLESFKGAMIFASHDHQLLQTIATRIINLSKDQFYNKEISYDEYLKEVMNVAE
HHHHHCCEEEEECCCHHHHHHHHHHHHCCCHHHHCCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MLTVNNVGLRYGDKKLFEDVSIKFLPGNCYGLIGANGAGKSTFLKVLSGELDSQSGNVHI
CEEECCCCCCCCCHHHHCCCEEEEECCCEEEEEECCCCCHHHHHHHHHCCCCCCCCCEEE
GSGERLAVLRQDHFQYDDELVLNTVIMGHERLYKIMDEKNAIYMKEDFSDADGIRAAELE
CCCCEEEEEEHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCEEEECC
GEFAELDGWEAESDAAVLLNGLGIPTDLHGKLMKDLTGGEKVKVLLAQALFGKPDILLLD
CCHHHCCCCCCCCCCEEEEECCCCCCCHHHHHHHHCCCCHHHHHHHHHHHCCCCCEEEEE
EPTNHLDIRAIHWLEEFLINFDNTVIVVSHDRHFLNKVCTHIADLDFSKIKLYVGNYDFW
CCCCCCCHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHCCCCEEEEEEECCEEEE
YESSQLAQTMMGDRNKKKEEKMKELQDFIARFSANASKSKQATSRKKMLEKITLEDIQPS
ECHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCC
SRRYPFIQFKPDREVGNDLLTVTNLSKTIDGVKILDNLSFSINRNDKVALVGDDEVAKTV
CCCCCEEEECCCHHHCCCEEEEEHHHHHHCCHHHHHCCEEEECCCCEEEEECCHHHHHHH
LFQILAGEMEPDEGSYKWGITTSQSYFPKDNSEFFEENDMSLVEWLRQFSPEDDSEAFLR
HHHHHHCCCCCCCCCEEECCCCCCCCCCCCCCHHHHCCCHHHHHHHHHCCCCCCHHHHHH
GFLGRMLFSGDEVLKKVRVLSGGEKVRCMLSKMMLSGSNVLLLDEPTNHLDLESITALNN
HHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHH
GLESFKGAMIFASHDHQLLQTIATRIINLSKDQFYNKEISYDEYLKEVMNVAE
HHHHHCCEEEEECCCHHHHHHHHHHHHCCCHHHHCCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]