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The map label for this gene is yaeL [C]

Identifier: 116872749

GI number: 116872749

Start: 1322678

End: 1323940

Strand: Direct

Name: yaeL [C]

Synonym: lwe1333

Alternate gene names: 116872749

Gene position: 1322678-1323940 (Clockwise)

Preceding gene: 116872748

Following gene: 116872750

Centisome position: 47.0

GC content: 37.05

Gene sequence:

>1263_bases
TTGACAACTATTATTGCTTTTATTTTCGTATTCGGTCTGATTGTATTTTTCCATGAACTAGGACATTTTCTTTTTGCAAA
ACGTGCTGGCATTATGGTAAAAGATTTTTCAATTGGATTTGGACCGAAAATCTTCGCTTATCGAAAAAAAGAAACACAGT
ACACGATTCGCTTACTACCAATTGGTGGATATGTTCGTATGGCTGGAGAAGATGGCGAGGAAATTGAGCTAAAACCCGGC
TATCGTGTGGGGCTAGAATTAACTCCAGAAGAAACCGTGAGCAAGATTATTGTTAACGGCAAAGACCAATATGTCAATGC
ACAACCTATCGAGGTATCGCTTTGTGATTTAGAGAAAGAGTTGTTCATTGAAGGTTATGAAGATTATGATGATACAAAAA
AAGTGCGTTATCAAGTAGAACGTAATGCGCTTGTGATAGATGGTAAAATCGAAACTATGATAACTCCATATGATCGTTCT
TTTAATGCGAAATCATTAGGGAATCGAGCAATGACAATTTTTGCTGGGCCACTTTTTAACTTTATTTTGGCTATTTTAAT
TTTTACTGCACTAGCTTTTGTTCAGGGCGGAGTACCAAGCACTGATAATACGCTTGGGAATGTTTTACCAGACGGAGCTG
CTGCACAAGCTGGTCTTGAAAAAGGAGACGAGGTTCTTTCCATCAACGGAAAAGAAACGAAATCGTGGACAAATATTGTT
CAAAGTGTTTCCGAAAATCCGGGAAAAACACTTGATTTCAAAATCGAGCGTGACGGTAAAACACAAGATATTAATGTAAA
ACCGGAAACGCAAAAAGAAAATGGCAAAGAAGTTGGGAAAATTGGAGTAGAAACACCGATGGATACTTCATTTGCTGCTA
AAATAACTAACGGATTTACGCAGACCTGGAATTGGATTGTTCAAATATTTACGATTTTAGGTAACATGGTTACAGGTGGA
TTTTCACTAGATATGCTAAATGGTCCTGTTGGTATTTATACTAGTACACAACAAGTTGTTCAATATGGTTTTATGACGGT
TCTAAACTGGACTGCTGTTTTAAGTATTAACTTAGGAATTGTAAACTTGCTACCGCTACCAGCACTTGATGGTGGGCGTT
TGATGTTCTTCTTATATGAACTCGTTCGCGGTAAACCAATTGATCCTAAAAAAGAAGGTATTATCCATTTTGCTGGATTT
GCGCTTTTAATGGTTCTAATGATTCTTGTGACATGGAACGATATTCAACGAGCATTTTTCTAA

Upstream 100 bases:

>100_bases
CGTCATACTAGTATTTCTGAGCCTGACTTGGATACGATTTTACAAGTCGATCAAGAAACACGCGCGTATGTAAAGACACT
TTTATAGAGGTGAAACTATT

Downstream 100 bases:

>100_bases
AACAGAAAGACTAATAAAGGGAAAAAAGGGGTGTTTTAAATGCGTCAAACGATGACATTTATACCAACATTAAAAGAAGT
TCCGGCGGATGCGGAAGTAA

Product: membrane-associated zinc metalloprotease, putative

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 420; Mature: 419

Protein sequence:

>420_residues
MTTIIAFIFVFGLIVFFHELGHFLFAKRAGIMVKDFSIGFGPKIFAYRKKETQYTIRLLPIGGYVRMAGEDGEEIELKPG
YRVGLELTPEETVSKIIVNGKDQYVNAQPIEVSLCDLEKELFIEGYEDYDDTKKVRYQVERNALVIDGKIETMITPYDRS
FNAKSLGNRAMTIFAGPLFNFILAILIFTALAFVQGGVPSTDNTLGNVLPDGAAAQAGLEKGDEVLSINGKETKSWTNIV
QSVSENPGKTLDFKIERDGKTQDINVKPETQKENGKEVGKIGVETPMDTSFAAKITNGFTQTWNWIVQIFTILGNMVTGG
FSLDMLNGPVGIYTSTQQVVQYGFMTVLNWTAVLSINLGIVNLLPLPALDGGRLMFFLYELVRGKPIDPKKEGIIHFAGF
ALLMVLMILVTWNDIQRAFF

Sequences:

>Translated_420_residues
MTTIIAFIFVFGLIVFFHELGHFLFAKRAGIMVKDFSIGFGPKIFAYRKKETQYTIRLLPIGGYVRMAGEDGEEIELKPG
YRVGLELTPEETVSKIIVNGKDQYVNAQPIEVSLCDLEKELFIEGYEDYDDTKKVRYQVERNALVIDGKIETMITPYDRS
FNAKSLGNRAMTIFAGPLFNFILAILIFTALAFVQGGVPSTDNTLGNVLPDGAAAQAGLEKGDEVLSINGKETKSWTNIV
QSVSENPGKTLDFKIERDGKTQDINVKPETQKENGKEVGKIGVETPMDTSFAAKITNGFTQTWNWIVQIFTILGNMVTGG
FSLDMLNGPVGIYTSTQQVVQYGFMTVLNWTAVLSINLGIVNLLPLPALDGGRLMFFLYELVRGKPIDPKKEGIIHFAGF
ALLMVLMILVTWNDIQRAFF
>Mature_419_residues
TTIIAFIFVFGLIVFFHELGHFLFAKRAGIMVKDFSIGFGPKIFAYRKKETQYTIRLLPIGGYVRMAGEDGEEIELKPGY
RVGLELTPEETVSKIIVNGKDQYVNAQPIEVSLCDLEKELFIEGYEDYDDTKKVRYQVERNALVIDGKIETMITPYDRSF
NAKSLGNRAMTIFAGPLFNFILAILIFTALAFVQGGVPSTDNTLGNVLPDGAAAQAGLEKGDEVLSINGKETKSWTNIVQ
SVSENPGKTLDFKIERDGKTQDINVKPETQKENGKEVGKIGVETPMDTSFAAKITNGFTQTWNWIVQIFTILGNMVTGGF
SLDMLNGPVGIYTSTQQVVQYGFMTVLNWTAVLSINLGIVNLLPLPALDGGRLMFFLYELVRGKPIDPKKEGIIHFAGFA
LLMVLMILVTWNDIQRAFF

Specific function: Unknown

COG id: COG0750

COG function: function code M; Predicted membrane-associated Zn-dependent proteases 1

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PDZ (DHR) domain [H]

Homologues:

Organism=Escherichia coli, GI1786373, Length=230, Percent_Identity=33.4782608695652, Blast_Score=139, Evalue=4e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR004387
- InterPro:   IPR008915 [H]

Pfam domain/function: PF00595 PDZ; PF02163 Peptidase_M50 [H]

EC number: NA

Molecular weight: Translated: 46696; Mature: 46565

Theoretical pI: Translated: 5.05; Mature: 5.05

Prosite motif: PS50106 PDZ ; PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTIIAFIFVFGLIVFFHELGHFLFAKRAGIMVKDFSIGFGPKIFAYRKKETQYTIRLLP
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCEEEEEEECCCEEEEEEEE
IGGYVRMAGEDGEEIELKPGYRVGLELTPEETVSKIIVNGKDQYVNAQPIEVSLCDLEKE
ECCEEEECCCCCCEEEECCCEEEEEEECHHHHHHHHEECCCCCEECCCCCEEEEECCCHH
LFIEGYEDYDDTKKVRYQVERNALVIDGKIETMITPYDRSFNAKSLGNRAMTIFAGPLFN
HHCCCCCCCCCHHHHHEEEECCEEEECCCEEEEECCCCCCCCCHHCCCCEEEEEHHHHHH
FILAILIFTALAFVQGGVPSTDNTLGNVLPDGAAAQAGLEKGDEVLSINGKETKSWTNIV
HHHHHHHHHHHHHHCCCCCCCCCCHHCCCCCCHHHHHHHCCCCCEEEECCCCHHHHHHHH
QSVSENPGKTLDFKIERDGKTQDINVKPETQKENGKEVGKIGVETPMDTSFAAKITNGFT
HHHHCCCCCEEEEEEECCCCCEEECCCCCCCCCCCCHHHCCCCCCCCCCHHHHHHHCCHH
QTWNWIVQIFTILGNMVTGGFSLDMLNGPVGIYTSTQQVVQYGFMTVLNWTAVLSINLGI
HHHHHHHHHHHHHHHHHCCCEEEEECCCCEEEEECHHHHHHHHHHHHHHEEEEEEECCCE
VNLLPLPALDGGRLMFFLYELVRGKPIDPKKEGIIHFAGFALLMVLMILVTWNDIQRAFF
EEEECCCCCCCCHHHHHHHHHHCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TTIIAFIFVFGLIVFFHELGHFLFAKRAGIMVKDFSIGFGPKIFAYRKKETQYTIRLLP
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCEEEEEEECCCEEEEEEEE
IGGYVRMAGEDGEEIELKPGYRVGLELTPEETVSKIIVNGKDQYVNAQPIEVSLCDLEKE
ECCEEEECCCCCCEEEECCCEEEEEEECHHHHHHHHEECCCCCEECCCCCEEEEECCCHH
LFIEGYEDYDDTKKVRYQVERNALVIDGKIETMITPYDRSFNAKSLGNRAMTIFAGPLFN
HHCCCCCCCCCHHHHHEEEECCEEEECCCEEEEECCCCCCCCCHHCCCCEEEEEHHHHHH
FILAILIFTALAFVQGGVPSTDNTLGNVLPDGAAAQAGLEKGDEVLSINGKETKSWTNIV
HHHHHHHHHHHHHHCCCCCCCCCCHHCCCCCCHHHHHHHCCCCCEEEECCCCHHHHHHHH
QSVSENPGKTLDFKIERDGKTQDINVKPETQKENGKEVGKIGVETPMDTSFAAKITNGFT
HHHHCCCCCEEEEEEECCCCCEEECCCCCCCCCCCCHHHCCCCCCCCCCHHHHHHHCCHH
QTWNWIVQIFTILGNMVTGGFSLDMLNGPVGIYTSTQQVVQYGFMTVLNWTAVLSINLGI
HHHHHHHHHHHHHHHHHCCCEEEEECCCCEEEEECHHHHHHHHHHHHHHEEEEEEECCCE
VNLLPLPALDGGRLMFFLYELVRGKPIDPKKEGIIHFAGFALLMVLMILVTWNDIQRAFF
EEEECCCCCCCCHHHHHHHHHHCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11679669 [H]