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The map label for this gene is luxS [H]

Identifier: 116872721

GI number: 116872721

Start: 1296034

End: 1296501

Strand: Direct

Name: luxS [H]

Synonym: lwe1305

Alternate gene names: 116872721

Gene position: 1296034-1296501 (Clockwise)

Preceding gene: 116872720

Following gene: 116872723

Centisome position: 46.05

GC content: 37.39

Gene sequence:

>468_bases
ATGACAGAAAAAATGAATGTAGAAAGTTTTAATTTAGATCATACGAAAGTAAAAGCACCTTTTGTTAGACTAGCGGGAAC
GAAGGTTGGTTTGCACGGAGATGAAATTTATAAATACGATGTCCGTTTTAAACAGCCTAATAAAGAACATATGGATATGC
CAGCACTTCATTCACTGGAGCATTTAATGGCGGAACTTGCTAGAAACCATACTGATAAATTAGTTGATATTAGCCCTATG
GGATGTCAAACAGGTTTTTATGTATCTTTCATCAACCATAATGACTATGATGATGCATTAGAAATTTTAGCTACAACGTT
AACAGATGTTTTAGCTGCAACAGAAGTACCAGCCTGTAATGAGGTGCAATGTGGTTGGGCAGCGAGTCATAGCCTTGAAG
GAGCTCAAGCGCTTGCGGCAGAATTTTTAGCTAAACGAGACGAATGGAAAAATGTGTTTGGTGAATAA

Upstream 100 bases:

>100_bases
GTGACGCGAAAGACGAGTAATGAGAAAGAATCTTTGCATTGAAAATATGCAAGGATTCTTTTTTTTGATATAATGACTAG
GAATAAAAGGAGGGGCACGC

Downstream 100 bases:

>100_bases
AAGAAAAACTCAACCGATTTAATGGTTGAGTTTTATTTGTTCATAGCATTTGTAAGCATTGAGACATAAGCTTTTGCACC
GGTTTTGGTCAAATGAACGC

Product: S-ribosylhomocysteinase

Products: NA

Alternate protein names: AI-2 synthesis protein; Autoinducer-2 production protein luxS [H]

Number of amino acids: Translated: 155; Mature: 154

Protein sequence:

>155_residues
MTEKMNVESFNLDHTKVKAPFVRLAGTKVGLHGDEIYKYDVRFKQPNKEHMDMPALHSLEHLMAELARNHTDKLVDISPM
GCQTGFYVSFINHNDYDDALEILATTLTDVLAATEVPACNEVQCGWAASHSLEGAQALAAEFLAKRDEWKNVFGE

Sequences:

>Translated_155_residues
MTEKMNVESFNLDHTKVKAPFVRLAGTKVGLHGDEIYKYDVRFKQPNKEHMDMPALHSLEHLMAELARNHTDKLVDISPM
GCQTGFYVSFINHNDYDDALEILATTLTDVLAATEVPACNEVQCGWAASHSLEGAQALAAEFLAKRDEWKNVFGE
>Mature_154_residues
TEKMNVESFNLDHTKVKAPFVRLAGTKVGLHGDEIYKYDVRFKQPNKEHMDMPALHSLEHLMAELARNHTDKLVDISPMG
CQTGFYVSFINHNDYDDALEILATTLTDVLAATEVPACNEVQCGWAASHSLEGAQALAAEFLAKRDEWKNVFGE

Specific function: Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is ca

COG id: COG1854

COG function: function code T; LuxS protein involved in autoinducer AI2 synthesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the luxS family [H]

Homologues:

Organism=Escherichia coli, GI1789043, Length=146, Percent_Identity=41.7808219178082, Blast_Score=116, Evalue=8e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011249
- InterPro:   IPR003815
- ProDom:   PD013172 [H]

Pfam domain/function: PF02664 LuxS [H]

EC number: =4.4.1.21 [H]

Molecular weight: Translated: 17367; Mature: 17236

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEKMNVESFNLDHTKVKAPFVRLAGTKVGLHGDEIYKYDVRFKQPNKEHMDMPALHSLE
CCCCCCCCCCCCCCHHHHCCEEEECCCEECCCCCEEEEEEEEECCCCHHHCCCHHHHHHH
HLMAELARNHTDKLVDISPMGCQTGFYVSFINHNDYDDALEILATTLTDVLAATEVPACN
HHHHHHHHCCCCCEEECCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCC
EVQCGWAASHSLEGAQALAAEFLAKRDEWKNVFGE
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TEKMNVESFNLDHTKVKAPFVRLAGTKVGLHGDEIYKYDVRFKQPNKEHMDMPALHSLE
CCCCCCCCCCCCCHHHHCCEEEECCCEECCCCCEEEEEEEEECCCCHHHCCCHHHHHHH
HLMAELARNHTDKLVDISPMGCQTGFYVSFINHNDYDDALEILATTLTDVLAATEVPACN
HHHHHHHHCCCCCEEECCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCC
EVQCGWAASHSLEGAQALAAEFLAKRDEWKNVFGE
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11679669 [H]