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The map label for this gene is sirC [H]

Identifier: 116872515

GI number: 116872515

Start: 1116684

End: 1117148

Strand: Direct

Name: sirC [H]

Synonym: lwe1099

Alternate gene names: 116872515

Gene position: 1116684-1117148 (Clockwise)

Preceding gene: 116872511

Following gene: 116872516

Centisome position: 39.68

GC content: 35.27

Gene sequence:

>465_bases
ATGAAGTATCCGATAATGCTTGATATTACAGGGAAAAGAGTAGTCATAATTGGTGGTGGAAATGTAGCCCTTCGTAAAAT
AAAGGGATTGATTGATACGGGTGCTGATATTTTAGTTGTCGCGCCACATATTTTGCCAGAAATAAAAGCGTTTGATGTGC
GAATAAAGGAAGAAGCGTACCGTACAGAACATCTTGAGGGAGCTTTTATGCTATTTATTTGTACGAATAATCCAGAAGTG
AATCAAATGGTTTTACGCGATAGTAAGCCAGATCAATTAGTGAATGATACGACGGAACAAGCTAATTCTCATTTTTTTAA
TATGGCAACAGTGATGAAAAACGATCTATTAGTTGGTATTTCAACAGTTGGAGGGAATCCTGGATATGCGAAAAAAGTTA
AGCGAGAAATTGGTCAGTTAGTAGAAAATATAGCAACAGAAGAAATTAAAAATCGAAACAAATAA

Upstream 100 bases:

>100_bases
ATTAAACATTTACTTTACCTCCTTTTGAATTATTTTAACTATACCCGAAAAATACGTCGAATATGTGTTAAAATGAAGAA
AAATAGGCGGAGGATTGATA

Downstream 100 bases:

>100_bases
CCGAAAACCTGCTAATTTTAGTAGGTTTTTTTATTCTATTATATTGCTCTCTTTTAGGTTGCAAAATTTTACTATAGATT
TTGGAATGTAAACGCTCTAT

Product: siroheme synthase subunit family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 154; Mature: 154

Protein sequence:

>154_residues
MKYPIMLDITGKRVVIIGGGNVALRKIKGLIDTGADILVVAPHILPEIKAFDVRIKEEAYRTEHLEGAFMLFICTNNPEV
NQMVLRDSKPDQLVNDTTEQANSHFFNMATVMKNDLLVGISTVGGNPGYAKKVKREIGQLVENIATEEIKNRNK

Sequences:

>Translated_154_residues
MKYPIMLDITGKRVVIIGGGNVALRKIKGLIDTGADILVVAPHILPEIKAFDVRIKEEAYRTEHLEGAFMLFICTNNPEV
NQMVLRDSKPDQLVNDTTEQANSHFFNMATVMKNDLLVGISTVGGNPGYAKKVKREIGQLVENIATEEIKNRNK
>Mature_154_residues
MKYPIMLDITGKRVVIIGGGNVALRKIKGLIDTGADILVVAPHILPEIKAFDVRIKEEAYRTEHLEGAFMLFICTNNPEV
NQMVLRDSKPDQLVNDTTEQANSHFFNMATVMKNDLLVGISTVGGNPGYAKKVKREIGQLVENIATEEIKNRNK

Specific function: Catalyzes the dehydrogenation of precorrin-2 to form sirohydrochlorin used as precursor in both siroheme biosynthesis and in the anaerobic branch of adenosylcobalamin biosynthesis [H]

COG id: COG1648

COG function: function code H; Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR006367 [H]

Pfam domain/function: NA

EC number: =1.3.1.76 [H]

Molecular weight: Translated: 17120; Mature: 17120

Theoretical pI: Translated: 8.46; Mature: 8.46

Prosite motif: PS00141 ASP_PROTEASE ; PS50175 ASP_PROT_RETROV

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKYPIMLDITGKRVVIIGGGNVALRKIKGLIDTGADILVVAPHILPEIKAFDVRIKEEAY
CCCCEEEEECCCEEEEEECCCEEEHHHHHHHCCCCCEEEECCCCCCCCHHEEEEEHHHHH
RTEHLEGAFMLFICTNNPEVNQMVLRDSKPDQLVNDTTEQANSHFFNMATVMKNDLLVGI
HHHCCCCEEEEEEECCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEE
STVGGNPGYAKKVKREIGQLVENIATEEIKNRNK
EECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKYPIMLDITGKRVVIIGGGNVALRKIKGLIDTGADILVVAPHILPEIKAFDVRIKEEAY
CCCCEEEEECCCEEEEEECCCEEEHHHHHHHCCCCCEEEECCCCCCCCHHEEEEEHHHHH
RTEHLEGAFMLFICTNNPEVNQMVLRDSKPDQLVNDTTEQANSHFFNMATVMKNDLLVGI
HHHCCCCEEEEEEECCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEE
STVGGNPGYAKKVKREIGQLVENIATEEIKNRNK
EECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA