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The map label for this gene is tagD [H]

Identifier: 116872482

GI number: 116872482

Start: 1088219

End: 1088602

Strand: Direct

Name: tagD [H]

Synonym: lwe1066

Alternate gene names: 116872482

Gene position: 1088219-1088602 (Clockwise)

Preceding gene: 116872481

Following gene: 116872483

Centisome position: 38.67

GC content: 32.81

Gene sequence:

>384_bases
ATGAAAAAAGTAATTACATATGGTACATTTGATTTAATTCACTGGGGGCATATTCGGTTATTAGAACGAGCAAAAGCTCT
GGGTGATTACCTTATCGTAGCCATTTCAACAGATGAATTTAATCGAATGAAACACAAAGAAGCGTACCATAACTTTGAAC
ATCGTAAACTAATTTTAGAAGCGATAAGATATGTGGATGAAGTGATTCCAGAAAGTAACTGGGAACAAAAATTAGAAGAT
GTAAAAAATCGTGATATTGATATTTTTGTGATGGGTGATGACTGGGAAGGTGAGTTTGACTTCTTAAAACCATATTGTGA
AGTTGTTTATTTACCACGTACAGACGGTATTTCTACTTCCAAGATTAAAGATGATTTAAAATAG

Upstream 100 bases:

>100_bases
TTTGTTTTATTTTTAAAAGAACAGCTGGAAAAACAAGACAGCTAACAAGTAGAGAAATTTTTGTTTTCTTGATATACTAC
TAAAGAAAGTAGGTGGGCTG

Downstream 100 bases:

>100_bases
GCGTAGCACAAAACGGGCGGACTGGTAATGTTTAATTATTAGGTGGTGGGCTTGTTTTGTGCTATTATTATGTATAAATG
ATAACGAAAGAACTACTTAT

Product: glycerol-3-phosphate cytidylyltransferase

Products: NA

Alternate protein names: GCT; Gro-PCT; CDP-glycerol pyrophosphorylase; Teichoic acid biosynthesis protein D [H]

Number of amino acids: Translated: 127; Mature: 127

Protein sequence:

>127_residues
MKKVITYGTFDLIHWGHIRLLERAKALGDYLIVAISTDEFNRMKHKEAYHNFEHRKLILEAIRYVDEVIPESNWEQKLED
VKNRDIDIFVMGDDWEGEFDFLKPYCEVVYLPRTDGISTSKIKDDLK

Sequences:

>Translated_127_residues
MKKVITYGTFDLIHWGHIRLLERAKALGDYLIVAISTDEFNRMKHKEAYHNFEHRKLILEAIRYVDEVIPESNWEQKLED
VKNRDIDIFVMGDDWEGEFDFLKPYCEVVYLPRTDGISTSKIKDDLK
>Mature_127_residues
MKKVITYGTFDLIHWGHIRLLERAKALGDYLIVAISTDEFNRMKHKEAYHNFEHRKLILEAIRYVDEVIPESNWEQKLED
VKNRDIDIFVMGDDWEGEFDFLKPYCEVVYLPRTDGISTSKIKDDLK

Specific function: Provides activated glycerol phosphate for teichoic acid synthesis, via incorporation into both the linkage unit and the teichoic acid polymer by TagB and TagF [H]

COG id: COG0615

COG function: function code MI; Cytidylyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidylyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI296841136, Length=122, Percent_Identity=36.0655737704918, Blast_Score=72, Evalue=2e-13,
Organism=Homo sapiens, GI4505651, Length=122, Percent_Identity=36.0655737704918, Blast_Score=71, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR006409
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01467 CTP_transf_2 [H]

EC number: =2.7.7.39 [H]

Molecular weight: Translated: 15121; Mature: 15121

Theoretical pI: Translated: 5.28; Mature: 5.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKVITYGTFDLIHWGHIRLLERAKALGDYLIVAISTDEFNRMKHKEAYHNFEHRKLILE
CCCEEECCCCHHHHHHHHHHHHHHHHCCCEEEEEEECCHHHHHHHHHHHHCHHHHHHHHH
AIRYVDEVIPESNWEQKLEDVKNRDIDIFVMGDDWEGEFDFLKPYCEVVYLPRTDGISTS
HHHHHHHHCCCCCHHHHHHHHCCCCEEEEEECCCCCCCHHHHCCCHHEEECCCCCCCCHH
KIKDDLK
HHHCCCC
>Mature Secondary Structure
MKKVITYGTFDLIHWGHIRLLERAKALGDYLIVAISTDEFNRMKHKEAYHNFEHRKLILE
CCCEEECCCCHHHHHHHHHHHHHHHHCCCEEEEEEECCHHHHHHHHHHHHCHHHHHHHHH
AIRYVDEVIPESNWEQKLEDVKNRDIDIFVMGDDWEGEFDFLKPYCEVVYLPRTDGISTS
HHHHHHHHCCCCCHHHHHHHHCCCCEEEEEECCCCCCCHHHHCCCHHEEECCCCCCCCHH
KIKDDLK
HHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1906926; 8393871; 9384377; 9182537; 11487587; 10508782 [H]