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The map label for this gene is yqhD [H]

Identifier: 116871939

GI number: 116871939

Start: 554399

End: 555580

Strand: Direct

Name: yqhD [H]

Synonym: lwe0519

Alternate gene names: 116871939

Gene position: 554399-555580 (Clockwise)

Preceding gene: 116871921

Following gene: 116871940

Centisome position: 19.7

GC content: 36.63

Gene sequence:

>1182_bases
ATGCAAAAAGAAATGTTGAATTTTGATTATTATAACCCTACTCATATTATTTTTGGTAAAAATCGTTTAGAAGAATTAAA
TGAGGTTATTCCTCAAGATAAAAAAGTTTTGTTACTTTATGGTGGCGGTAGTGTTAAGCGTTTTGGTACTTTAGATAAAG
TAAAAGAAGTGCTTAAATCACGAGAAGTAGGCGAATTTGGTGGAATTGAAGCGAACCCTACATACGAAACATTAATCAAA
GCAATTAAATTAGTGAAAGAAGAAAACTATGACTTTTTGCTTGCTATTGGTGGCGGCTCTGTTATTGATGGTACAAAATT
TGTTGCTGCAGGTGCATTGTTTGATGGGAATCCAATAGACATTTTTGGTAGTGGAATTGGTGAAAAACGTCCTATCACAC
AGGCGCTTCCTTTTGGAACTGTTTTAACTCTCCCAGCAACTGGTTCTGAAATGAATAGTGGTGGTGTTATCACTTTTGTT
GAAAAGAAAGCGAAACTTGGCTTTGGTAGTGCGTATACTTTCCCAGTTTTCTCTTTACTTGACCCGGAACTCACATACAC
TCTGCCAAAACGTCAATTAGCGAACGGAATTATGGATGCATATGTACATGTTATGGAACAATATATGACGTATCCAGTTG
GTGCTTTGCTACAAGATCGTTATGCCGAAAGCTTACTACAAACATTAATTGAAATTGGTCCAGATGTTATTGATGAAGAT
AATCATGATTATAATACACGAGCTACTTTCATGTGGTCTGCAACCAATGCACTTAATGGAACCTTATCTAGAGGCGTTCC
GCAAGACTGGGCAAGCCATGGTTTAGGACATGAAATTACAGCACTTTATGGAATTGATCATGCACGTACGTTAGCAATTG
TACTTCCATCCCTATTAAATGTTCGTCGTAATGAAAAACATGATAAATTAGTACAATATGCTGAGCGAGTGTGGGGTATT
GCAGACGGTAACGATGATGAAAAAATTGATGCAGCGATTCTGAAAACACGTGAGTTTTTTGAAAGTTTAGGTGCAGGGAC
TAGATTTAGCGATTATGGTCTTGGTGAAGAAGTAGTAGATGTACTTGTGGACCAACTAGAACGTCATGGTTTAACAAATA
TTTCGGAACACGGTGATCAAACTTTAGAAGTCTCTCGTCAAATTTATAAAAATGCTTTATAA

Upstream 100 bases:

>100_bases
ATATAAATGGAAACTTTTGGCTATAGGTTTAAATTTTCTAAAAAAAGTGTATTATTAACTATGCTATGTAAATTTATAAA
CCGAAAGAAGGACGTTAAAA

Downstream 100 bases:

>100_bases
TGGTAAACGAAACTTTTCGTAACTAGCATAAACTGCATTTACTTAATTTAATATGAAAAGAGATGAAAGAGGGCGAATTT
TCTTGAGTACAGAGAATGCA

Product: alcohol dehydrogenase, iron-dependent

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 393; Mature: 393

Protein sequence:

>393_residues
MQKEMLNFDYYNPTHIIFGKNRLEELNEVIPQDKKVLLLYGGGSVKRFGTLDKVKEVLKSREVGEFGGIEANPTYETLIK
AIKLVKEENYDFLLAIGGGSVIDGTKFVAAGALFDGNPIDIFGSGIGEKRPITQALPFGTVLTLPATGSEMNSGGVITFV
EKKAKLGFGSAYTFPVFSLLDPELTYTLPKRQLANGIMDAYVHVMEQYMTYPVGALLQDRYAESLLQTLIEIGPDVIDED
NHDYNTRATFMWSATNALNGTLSRGVPQDWASHGLGHEITALYGIDHARTLAIVLPSLLNVRRNEKHDKLVQYAERVWGI
ADGNDDEKIDAAILKTREFFESLGAGTRFSDYGLGEEVVDVLVDQLERHGLTNISEHGDQTLEVSRQIYKNAL

Sequences:

>Translated_393_residues
MQKEMLNFDYYNPTHIIFGKNRLEELNEVIPQDKKVLLLYGGGSVKRFGTLDKVKEVLKSREVGEFGGIEANPTYETLIK
AIKLVKEENYDFLLAIGGGSVIDGTKFVAAGALFDGNPIDIFGSGIGEKRPITQALPFGTVLTLPATGSEMNSGGVITFV
EKKAKLGFGSAYTFPVFSLLDPELTYTLPKRQLANGIMDAYVHVMEQYMTYPVGALLQDRYAESLLQTLIEIGPDVIDED
NHDYNTRATFMWSATNALNGTLSRGVPQDWASHGLGHEITALYGIDHARTLAIVLPSLLNVRRNEKHDKLVQYAERVWGI
ADGNDDEKIDAAILKTREFFESLGAGTRFSDYGLGEEVVDVLVDQLERHGLTNISEHGDQTLEVSRQIYKNAL
>Mature_393_residues
MQKEMLNFDYYNPTHIIFGKNRLEELNEVIPQDKKVLLLYGGGSVKRFGTLDKVKEVLKSREVGEFGGIEANPTYETLIK
AIKLVKEENYDFLLAIGGGSVIDGTKFVAAGALFDGNPIDIFGSGIGEKRPITQALPFGTVLTLPATGSEMNSGGVITFV
EKKAKLGFGSAYTFPVFSLLDPELTYTLPKRQLANGIMDAYVHVMEQYMTYPVGALLQDRYAESLLQTLIEIGPDVIDED
NHDYNTRATFMWSATNALNGTLSRGVPQDWASHGLGHEITALYGIDHARTLAIVLPSLLNVRRNEKHDKLVQYAERVWGI
ADGNDDEKIDAAILKTREFFESLGAGTRFSDYGLGEEVVDVLVDQLERHGLTNISEHGDQTLEVSRQIYKNAL

Specific function: NADP-dependent ADH activity [H]

COG id: COG1979

COG function: function code C; Uncharacterized oxidoreductases, Fe-dependent alcohol dehydrogenase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI133922590, Length=154, Percent_Identity=26.6233766233766, Blast_Score=66, Evalue=5e-11,
Organism=Escherichia coli, GI1789386, Length=390, Percent_Identity=56.1538461538462, Blast_Score=436, Evalue=1e-123,
Organism=Escherichia coli, GI48994951, Length=338, Percent_Identity=24.8520710059172, Blast_Score=85, Evalue=7e-18,
Organism=Escherichia coli, GI87082107, Length=285, Percent_Identity=25.9649122807018, Blast_Score=70, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17537053, Length=152, Percent_Identity=30.9210526315789, Blast_Score=77, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6321181, Length=301, Percent_Identity=25.9136212624585, Blast_Score=83, Evalue=7e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001670
- InterPro:   IPR018211 [H]

Pfam domain/function: PF00465 Fe-ADH [H]

EC number: 1.1.-.- [C]

Molecular weight: Translated: 43500; Mature: 43500

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: PS00060 ADH_IRON_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKEMLNFDYYNPTHIIFGKNRLEELNEVIPQDKKVLLLYGGGSVKRFGTLDKVKEVLKS
CCCCCCCCCCCCCCEEEECCHHHHHHHHHCCCCCEEEEEECCCCCCCCCCHHHHHHHHHH
REVGEFGGIEANPTYETLIKAIKLVKEENYDFLLAIGGGSVIDGTKFVAAGALFDGNPID
CCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCEECCCHHEEECCEECCCCCE
IFGSGIGEKRPITQALPFGTVLTLPATGSEMNSGGVITFVEKKAKLGFGSAYTFPVFSLL
EEECCCCCCCCCHHHCCCCEEEEECCCCCCCCCCCEEEEEECHHCCCCCCCHHHHHHHHC
DPELTYTLPKRQLANGIMDAYVHVMEQYMTYPVGALLQDRYAESLLQTLIEIGPDVIDED
CCCCEEECCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCC
NHDYNTRATFMWSATNALNGTLSRGVPQDWASHGLGHEITALYGIDHARTLAIVLPSLLN
CCCCCCEEEEEEECCCHHCCHHHCCCCHHHHHCCCCCEEHHEECCCHHHHHHHHHHHHHH
VRRNEKHDKLVQYAERVWGIADGNDDEKIDAAILKTREFFESLGAGTRFSDYGLGEEVVD
HHCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHH
VLVDQLERHGLTNISEHGDQTLEVSRQIYKNAL
HHHHHHHHCCCCCCHHCCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MQKEMLNFDYYNPTHIIFGKNRLEELNEVIPQDKKVLLLYGGGSVKRFGTLDKVKEVLKS
CCCCCCCCCCCCCCEEEECCHHHHHHHHHCCCCCEEEEEECCCCCCCCCCHHHHHHHHHH
REVGEFGGIEANPTYETLIKAIKLVKEENYDFLLAIGGGSVIDGTKFVAAGALFDGNPID
CCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCEECCCHHEEECCEECCCCCE
IFGSGIGEKRPITQALPFGTVLTLPATGSEMNSGGVITFVEKKAKLGFGSAYTFPVFSLL
EEECCCCCCCCCHHHCCCCEEEEECCCCCCCCCCCEEEEEECHHCCCCCCCHHHHHHHHC
DPELTYTLPKRQLANGIMDAYVHVMEQYMTYPVGALLQDRYAESLLQTLIEIGPDVIDED
CCCCEEECCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCC
NHDYNTRATFMWSATNALNGTLSRGVPQDWASHGLGHEITALYGIDHARTLAIVLPSLLN
CCCCCCEEEEEEECCCHHCCHHHCCCCHHHHHCCCCCEEHHEECCCHHHHHHHHHHHHHH
VRRNEKHDKLVQYAERVWGIADGNDDEKIDAAILKTREFFESLGAGTRFSDYGLGEEVVD
HHCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHH
VLVDQLERHGLTNISEHGDQTLEVSRQIYKNAL
HHHHHHHHCCCCCCHHCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]