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The map label for this gene is yclF [H]

Identifier: 116871940

GI number: 116871940

Start: 555663

End: 557150

Strand: Direct

Name: yclF [H]

Synonym: lwe0520

Alternate gene names: 116871940

Gene position: 555663-557150 (Clockwise)

Preceding gene: 116871939

Following gene: 116871941

Centisome position: 19.75

GC content: 37.3

Gene sequence:

>1488_bases
TTGAGTACAGAGAATGCATCAAAGGAAAAAACATTTTTTGGGCATCCGCGTGGACTCGCTACCTTATTTAACACGGAATT
TTGGGAGCGATTTTCTTACTACGGGATGCGAGCAATACTTATCTATTATATGTATGATTCTGTTGCAAAAGGTGGGCTAG
GATTTGACCAAGCTACCGCGACAGCAATTATGTCTATATATGGATCACTTGTTTTTATGTCAGGAGTTATAGGCGGCTGG
TTTGCAGACCGGGTTCTTGGACCACGACAGACTATTTTTTATGGTGGCGTATTAATAATGGTTGGGCATATTGTCCTTGC
GCTTCCTAATGGTGGAGCAACTGCTCTATTTGTTTCAATGGCATTTATTATCTTAGGAACTGGTTTACTTAAGCCAAATG
TATCTAACGTTGTTGGCGATTTATATCCAGTAGGAGATAATCGTCGAGATGCTGGTTTTAGTATTTTTTACATGGGGATT
AATTTAGGTGCTTTTATTGCGCCGTTTATTGTTTCCGCGGTTTCTGACAAAGCTGGTAGTTTCCATGCTGGTTTTAGTGT
GGCAGCCGTTGGTATGGCAGTTGCGCTAATCGTTTATGTTCTTACAGGAAAACGTTATTTAAAAGAAGCAGGTAAAAAAG
TACCCAATCCACTTCAAAAATCCGAAACTATTAGCCTTATTTTAAAAATTGCAGGGATTATTGTGGGAATTGGTATTTTA
ATCGCCATTTTAACTATGATTACTGGTAGTTTAACTATTAATACTATTATTCTTGCAGTAACTGTTATGGGAGTTGGCGT
TCCACTTGCTTACTTTATCATGATGATGACTAGTAAGAAAACAGAAGCAGATGAAAAATCCAGATTAACTGCATACATAC
CGTTATTTTTAATTGCCGTTCTATTTTGGATGATTGAAGAACAAGGATCTAGTACGTTAGCAATTTTTGCTGCTGAAAGA
ACAGATTTATCCATTGGTAGTTTTCAATTAAATCCAGCTAATTTTCAATCACTTAATCCTGTATTTGTTATTATTCTTTC
ACCAGTTTTTGCATGGATTTGGACAAAACTTGGAGATAGACAACCATCTACACCGCGTAAATTCGCGTTAGGATTATTTT
TCGCTGGTTTATCTTTTGTTATTATGATGTTCCCAGGAATTATTCATGGAAATACAACAACACTTGTAAGCCCGCTTTGG
TTAGTATTAAGTTTCTTCATCTGTATTTTTGGTGAAATGTTTATCTCGCCAGTTGGTTTATCAGCAACTACAAAATTAGC
GCCAAAAGCTTTTGCATCTCAAACAATGAGTCTTTGGTTCCTGTCTGACGCAATGGGACAAGCGTTTAACGCACAAGCAA
CGCAGTTCTTTAGCGCCGATACAGAAATTGCTTATTTTGGAATAACTGGCTTTGTGGCCATAGCCTTCGCAATAGGATTA
TTCATTTTAGCGCCATTCTTGAAAAAATACATGAAGGGCGTTCATTAA

Upstream 100 bases:

>100_bases
TATAAAAATGCTTTATAATGGTAAACGAAACTTTTCGTAACTAGCATAAACTGCATTTACTTAATTTAATATGAAAAGAG
ATGAAAGAGGGCGAATTTTC

Downstream 100 bases:

>100_bases
ATAAATGCAAAAAACACTTTCTCGATATTTGGAGGAAGTGTTTTTTGTTCATATTTTTATTTCCAAAAATATTTATACTA
ATCATGACAAAATCTAAAAA

Product: proton-dependent oligopeptide transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 495; Mature: 494

Protein sequence:

>495_residues
MSTENASKEKTFFGHPRGLATLFNTEFWERFSYYGMRAILIYYMYDSVAKGGLGFDQATATAIMSIYGSLVFMSGVIGGW
FADRVLGPRQTIFYGGVLIMVGHIVLALPNGGATALFVSMAFIILGTGLLKPNVSNVVGDLYPVGDNRRDAGFSIFYMGI
NLGAFIAPFIVSAVSDKAGSFHAGFSVAAVGMAVALIVYVLTGKRYLKEAGKKVPNPLQKSETISLILKIAGIIVGIGIL
IAILTMITGSLTINTIILAVTVMGVGVPLAYFIMMMTSKKTEADEKSRLTAYIPLFLIAVLFWMIEEQGSSTLAIFAAER
TDLSIGSFQLNPANFQSLNPVFVIILSPVFAWIWTKLGDRQPSTPRKFALGLFFAGLSFVIMMFPGIIHGNTTTLVSPLW
LVLSFFICIFGEMFISPVGLSATTKLAPKAFASQTMSLWFLSDAMGQAFNAQATQFFSADTEIAYFGITGFVAIAFAIGL
FILAPFLKKYMKGVH

Sequences:

>Translated_495_residues
MSTENASKEKTFFGHPRGLATLFNTEFWERFSYYGMRAILIYYMYDSVAKGGLGFDQATATAIMSIYGSLVFMSGVIGGW
FADRVLGPRQTIFYGGVLIMVGHIVLALPNGGATALFVSMAFIILGTGLLKPNVSNVVGDLYPVGDNRRDAGFSIFYMGI
NLGAFIAPFIVSAVSDKAGSFHAGFSVAAVGMAVALIVYVLTGKRYLKEAGKKVPNPLQKSETISLILKIAGIIVGIGIL
IAILTMITGSLTINTIILAVTVMGVGVPLAYFIMMMTSKKTEADEKSRLTAYIPLFLIAVLFWMIEEQGSSTLAIFAAER
TDLSIGSFQLNPANFQSLNPVFVIILSPVFAWIWTKLGDRQPSTPRKFALGLFFAGLSFVIMMFPGIIHGNTTTLVSPLW
LVLSFFICIFGEMFISPVGLSATTKLAPKAFASQTMSLWFLSDAMGQAFNAQATQFFSADTEIAYFGITGFVAIAFAIGL
FILAPFLKKYMKGVH
>Mature_494_residues
STENASKEKTFFGHPRGLATLFNTEFWERFSYYGMRAILIYYMYDSVAKGGLGFDQATATAIMSIYGSLVFMSGVIGGWF
ADRVLGPRQTIFYGGVLIMVGHIVLALPNGGATALFVSMAFIILGTGLLKPNVSNVVGDLYPVGDNRRDAGFSIFYMGIN
LGAFIAPFIVSAVSDKAGSFHAGFSVAAVGMAVALIVYVLTGKRYLKEAGKKVPNPLQKSETISLILKIAGIIVGIGILI
AILTMITGSLTINTIILAVTVMGVGVPLAYFIMMMTSKKTEADEKSRLTAYIPLFLIAVLFWMIEEQGSSTLAIFAAERT
DLSIGSFQLNPANFQSLNPVFVIILSPVFAWIWTKLGDRQPSTPRKFALGLFFAGLSFVIMMFPGIIHGNTTTLVSPLWL
VLSFFICIFGEMFISPVGLSATTKLAPKAFASQTMSLWFLSDAMGQAFNAQATQFFSADTEIAYFGITGFVAIAFAIGLF
ILAPFLKKYMKGVH

Specific function: Unknown

COG id: COG3104

COG function: function code E; Dipeptide/tripeptide permease

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PTR2/POT transporter (TC 2.A.17) family [H]

Homologues:

Organism=Homo sapiens, GI226371746, Length=381, Percent_Identity=27.0341207349081, Blast_Score=109, Evalue=5e-24,
Organism=Homo sapiens, GI4827008, Length=227, Percent_Identity=33.4801762114537, Blast_Score=106, Evalue=4e-23,
Organism=Homo sapiens, GI226371748, Length=373, Percent_Identity=26.0053619302949, Blast_Score=92, Evalue=8e-19,
Organism=Escherichia coli, GI1789911, Length=498, Percent_Identity=26.9076305220884, Blast_Score=201, Evalue=1e-52,
Organism=Escherichia coli, GI1787922, Length=448, Percent_Identity=29.9107142857143, Blast_Score=198, Evalue=5e-52,
Organism=Escherichia coli, GI1790572, Length=415, Percent_Identity=30.6024096385542, Blast_Score=189, Evalue=5e-49,
Organism=Escherichia coli, GI1786927, Length=422, Percent_Identity=31.042654028436, Blast_Score=182, Evalue=3e-47,
Organism=Caenorhabditis elegans, GI71987453, Length=400, Percent_Identity=27, Blast_Score=102, Evalue=5e-22,
Organism=Caenorhabditis elegans, GI17569141, Length=393, Percent_Identity=26.972010178117, Blast_Score=97, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17541704, Length=387, Percent_Identity=26.3565891472868, Blast_Score=75, Evalue=8e-14,
Organism=Drosophila melanogaster, GI28571098, Length=400, Percent_Identity=28.5, Blast_Score=112, Evalue=7e-25,
Organism=Drosophila melanogaster, GI28571102, Length=402, Percent_Identity=27.8606965174129, Blast_Score=110, Evalue=2e-24,
Organism=Drosophila melanogaster, GI28571100, Length=402, Percent_Identity=27.8606965174129, Blast_Score=110, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24639583, Length=378, Percent_Identity=26.984126984127, Blast_Score=100, Evalue=3e-21,
Organism=Drosophila melanogaster, GI24639581, Length=367, Percent_Identity=27.2479564032698, Blast_Score=99, Evalue=7e-21,
Organism=Drosophila melanogaster, GI24639585, Length=367, Percent_Identity=27.2479564032698, Blast_Score=99, Evalue=8e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR016196
- InterPro:   IPR000109
- InterPro:   IPR005279
- InterPro:   IPR018456 [H]

Pfam domain/function: PF00854 PTR2 [H]

EC number: NA

Molecular weight: Translated: 53570; Mature: 53439

Theoretical pI: Translated: 9.73; Mature: 9.73

Prosite motif: PS50850 MFS ; PS01023 PTR2_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHCCCC
>Mature Secondary Structure 
STENASKEKTFFGHPRGLATLFNTEFWERFSYYGMRAILIYYMYDSVAKGGLGFDQATA
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH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HHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377 [H]