Click here to switch to the map view.

The map label for this gene is licR [H]

Identifier: 116871786

GI number: 116871786

Start: 382591

End: 384525

Strand: Direct

Name: licR [H]

Synonym: lwe0366

Alternate gene names: 116871786

Gene position: 382591-384525 (Clockwise)

Preceding gene: 116871785

Following gene: 116871787

Centisome position: 13.6

GC content: 34.52

Gene sequence:

>1935_bases
ATGGGATACTTCGCTTATAAACGTTTGGAAACATTATATGGCATGCTCCTTGATGCTGGTAGCCACTTATCAGCTCAGAA
ACTCAGCCAAGAATTACATATTTCAGAACGAACGATACGAACGGATATCGCGAAATTAACTGAATTTCTAGAGAATCACG
GAGCGACCATAACGCTTACTCGAGGCGCGGGGTACAAAATAGAAATCCTTGACCCAGCTGCCTTTCAAGCTTTTCAAAAT
GAAAAGAACAAACCGAAAAATGCGGATTATTTTGATTTAGATAATCCAGAAGAACGCGTAAAATACGAGATTTTCTTGCT
TTTATCAAGTGCGGATTATATTAAATTAGAAGATTTAGCAGATACTATTTATGCTAGCCGAGCAACTATTTCGAACGATA
TGAAACAAGTTCGAAAAGTCATTGCATCGTATGATTTAACGCTTGTTTCTAAGCCTGGTAGCGGTGTGAAAATCGTTGGG
GAAGAAGAAAAAATGCGTTACACTTTAACAGCACTGATTGCTTCCAAAAAGGCGCCAGAATCGTATTTAGAAACATTTTT
CGAATGGCATAAACAAAAAGATAAACTGCAAAAATTAATGTCAGCTGTGACAGATTATTTCTTTGCAACGAATATTCGCT
TTACTGACGAAGCACTTCAAAACCTTTTACTACATATGATGATTCTTGTGGAACGAATTGAGCTAGGCCATTCATTAGAA
CAGTTTGAATTAACGGATGTCAGTGAAGAAGAAATCGTAATAGCCAATAAATTAGCTACTATTTTAGAGTCCCTTTTCGA
AATAACCATTTCATCTGCTGATAAAAATTATTTGCTTCTTCAAATCGCCAGTAAGCGGATATTGAATGTAGAAGATAAAG
AAATTAGCGAATTTGATGATTATGCTTATATTGAAGGGATGCTTAACCGAATTGAATCGCACTATTCCTATCATTTACAA
GATGATTTACAACTCAAAAAGGACTTGATTGCACATATTCATTCGATGTTATATCGTGTGAAATATCATATGACAGTTAA
AAATCCAATGACTGAACATATTAAACGTTATTATCCACTTGCATATGAAATCACACTAGATGCAGTAGAATCCTTAAAAA
AAGATTACCCTTATGATATTAATCAAAATGAATTAGCCTATTTAGCCCTTCATATCGGAGCATCTCTTGAACGAAATTAC
CAAATTTCTTATTACCGGCATAAATCAGCTTTAATTGTTTGTGGATCAGGCTTTGGAACCGCGCGAATCGTCGAAGCAAA
AGTGAAATCAGCTGTGAGCAATTTGGACATTACAAAAGTTGTCTCGATTCAAGAATATAACCGTTTTATCCATATTGAAG
AAGATATTATCCTGTCTACTGTAAGAATTCCTGAAAAAAATAAGCCAGTCATCAAAATCAGCAATATTCCAACTAATGAA
GAATTAAAAATGCTTGGAGCCATTATTCAAGAACAAACTGATTCTAACCGAGGTTTCCTTTCAAACTTCTTTACGGCTGA
ATTTTTTGCAAGAAGTGAATTAACTAGTAAATCAGCTATTCTGAAAGAAATGGTGAGCTCTTTGTATAAAAATGATATAG
TTGGCACAGACTTCTTAGGTTCTGTACTGGAACGAGAAAAGCTAGGTTCAACGGTTCTAGGAACTGGAATAGCGATTCCT
CATCCACTTGGTTTGATGGCAAAAGAAACTAAAATAGTTATTCGGATTTTAGATAAACCGATTAAATGGGACCAAAAACA
ATCTGTGCATGCTGTTTTTTTACTATGTATAAGTAAACATGATTATGAGGAAGCTATCAATATATATGAGTTGCTTGTAG
AACTTGTCCGTGAAGAATACGGAGAAAAACTTGCCAATTTAACTAACTTTCGTGAATTTACTACTTTAGCAAAGGATATT
TTAAAGAAAAAATGA

Upstream 100 bases:

>100_bases
AATAAATCAAATGAGAAACAAACCACATTAAAACATGCAAAAGTCCAAACTTATTTATTTGAAAAATAATGGATAACTAC
CGTAAAAAGGAGCTGCTAAA

Downstream 100 bases:

>100_bases
AGGCTGCATCTATTTTTTAAAGATGTAGCTTTTTTCGTGAATTTTTCGTGAATATTTTTACTTTTCCATTTGGTGAAAGT
CGATTTCATGGTACACTATA

Product: DeoR/PRD/PTS regulatory domain-containing protein

Products: NA

Alternate protein names: Putative phosphotransferase enzyme IIB component; Putative PTS system EIIB component; Putative phosphotransferase enzyme IIA component; Putative PTS system EIIA component [H]

Number of amino acids: Translated: 644; Mature: 643

Protein sequence:

>644_residues
MGYFAYKRLETLYGMLLDAGSHLSAQKLSQELHISERTIRTDIAKLTEFLENHGATITLTRGAGYKIEILDPAAFQAFQN
EKNKPKNADYFDLDNPEERVKYEIFLLLSSADYIKLEDLADTIYASRATISNDMKQVRKVIASYDLTLVSKPGSGVKIVG
EEEKMRYTLTALIASKKAPESYLETFFEWHKQKDKLQKLMSAVTDYFFATNIRFTDEALQNLLLHMMILVERIELGHSLE
QFELTDVSEEEIVIANKLATILESLFEITISSADKNYLLLQIASKRILNVEDKEISEFDDYAYIEGMLNRIESHYSYHLQ
DDLQLKKDLIAHIHSMLYRVKYHMTVKNPMTEHIKRYYPLAYEITLDAVESLKKDYPYDINQNELAYLALHIGASLERNY
QISYYRHKSALIVCGSGFGTARIVEAKVKSAVSNLDITKVVSIQEYNRFIHIEEDIILSTVRIPEKNKPVIKISNIPTNE
ELKMLGAIIQEQTDSNRGFLSNFFTAEFFARSELTSKSAILKEMVSSLYKNDIVGTDFLGSVLEREKLGSTVLGTGIAIP
HPLGLMAKETKIVIRILDKPIKWDQKQSVHAVFLLCISKHDYEEAINIYELLVELVREEYGEKLANLTNFREFTTLAKDI
LKKK

Sequences:

>Translated_644_residues
MGYFAYKRLETLYGMLLDAGSHLSAQKLSQELHISERTIRTDIAKLTEFLENHGATITLTRGAGYKIEILDPAAFQAFQN
EKNKPKNADYFDLDNPEERVKYEIFLLLSSADYIKLEDLADTIYASRATISNDMKQVRKVIASYDLTLVSKPGSGVKIVG
EEEKMRYTLTALIASKKAPESYLETFFEWHKQKDKLQKLMSAVTDYFFATNIRFTDEALQNLLLHMMILVERIELGHSLE
QFELTDVSEEEIVIANKLATILESLFEITISSADKNYLLLQIASKRILNVEDKEISEFDDYAYIEGMLNRIESHYSYHLQ
DDLQLKKDLIAHIHSMLYRVKYHMTVKNPMTEHIKRYYPLAYEITLDAVESLKKDYPYDINQNELAYLALHIGASLERNY
QISYYRHKSALIVCGSGFGTARIVEAKVKSAVSNLDITKVVSIQEYNRFIHIEEDIILSTVRIPEKNKPVIKISNIPTNE
ELKMLGAIIQEQTDSNRGFLSNFFTAEFFARSELTSKSAILKEMVSSLYKNDIVGTDFLGSVLEREKLGSTVLGTGIAIP
HPLGLMAKETKIVIRILDKPIKWDQKQSVHAVFLLCISKHDYEEAINIYELLVELVREEYGEKLANLTNFREFTTLAKDI
LKKK
>Mature_643_residues
GYFAYKRLETLYGMLLDAGSHLSAQKLSQELHISERTIRTDIAKLTEFLENHGATITLTRGAGYKIEILDPAAFQAFQNE
KNKPKNADYFDLDNPEERVKYEIFLLLSSADYIKLEDLADTIYASRATISNDMKQVRKVIASYDLTLVSKPGSGVKIVGE
EEKMRYTLTALIASKKAPESYLETFFEWHKQKDKLQKLMSAVTDYFFATNIRFTDEALQNLLLHMMILVERIELGHSLEQ
FELTDVSEEEIVIANKLATILESLFEITISSADKNYLLLQIASKRILNVEDKEISEFDDYAYIEGMLNRIESHYSYHLQD
DLQLKKDLIAHIHSMLYRVKYHMTVKNPMTEHIKRYYPLAYEITLDAVESLKKDYPYDINQNELAYLALHIGASLERNYQ
ISYYRHKSALIVCGSGFGTARIVEAKVKSAVSNLDITKVVSIQEYNRFIHIEEDIILSTVRIPEKNKPVIKISNIPTNEE
LKMLGAIIQEQTDSNRGFLSNFFTAEFFARSELTSKSAILKEMVSSLYKNDIVGTDFLGSVLEREKLGSTVLGTGIAIPH
PLGLMAKETKIVIRILDKPIKWDQKQSVHAVFLLCISKHDYEEAINIYELLVELVREEYGEKLANLTNFREFTTLAKDIL
KKK

Specific function: Positive regulator of the licABCH operon [H]

COG id: COG3711

COG function: function code K; Transcriptional antiterminator

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIB type-2 domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013196
- InterPro:   IPR007737
- InterPro:   IPR011608
- InterPro:   IPR016152
- InterPro:   IPR002178
- InterPro:   IPR013011
- InterPro:   IPR003501
- InterPro:   IPR011991 [H]

Pfam domain/function: PF08279 HTH_11; PF05043 Mga; PF00874 PRD; PF00359 PTS_EIIA_2; PF02302 PTS_IIB [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 73859; Mature: 73728

Theoretical pI: Translated: 6.07; Mature: 6.07

Prosite motif: PS51094 PTS_EIIA_TYPE_2 ; PS51099 PTS_EIIB_TYPE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGYFAYKRLETLYGMLLDAGSHLSAQKLSQELHISERTIRTDIAKLTEFLENHGATITLT
CCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEE
RGAGYKIEILDPAAFQAFQNEKNKPKNADYFDLDNPEERVKYEIFLLLSSADYIKLEDLA
CCCCEEEEEECHHHHHHHHCCCCCCCCCCCCCCCCHHHHHEEEEEEEEECCCCEEHHHHH
DTIYASRATISNDMKQVRKVIASYDLTLVSKPGSGVKIVGEEEKMRYTLTALIASKKAPE
HHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCEEEECCCHHHHHHHHHHHHCCCCCH
SYLETFFEWHKQKDKLQKLMSAVTDYFFATNIRFTDEALQNLLLHMMILVERIELGHSLE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEHHHHHHHHHHHHHHHHHHHHHCCCCC
QFELTDVSEEEIVIANKLATILESLFEITISSADKNYLLLQIASKRILNVEDKEISEFDD
CEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEHHHHHCCCCCHHHHHHHH
YAYIEGMLNRIESHYSYHLQDDLQLKKDLIAHIHSMLYRVKYHMTVKNPMTEHIKRYYPL
HHHHHHHHHHHHHHCEECCCHHHHHHHHHHHHHHHHHHHHHHEEEECCHHHHHHHHHCCE
AYEITLDAVESLKKDYPYDINQNELAYLALHIGASLERNYQISYYRHKSALIVCGSGFGT
EEEEEHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCCEEEEEEEECCEEEEEECCCCC
ARIVEAKVKSAVSNLDITKVVSIQEYNRFIHIEEDIILSTVRIPEKNKPVIKISNIPTNE
HHHHHHHHHHHHHCCCHHHEEEHHHCCCEEEECHHHEEEEEECCCCCCCEEEECCCCCCH
ELKMLGAIIQEQTDSNRGFLSNFFTAEFFARSELTSKSAILKEMVSSLYKNDIVGTDFLG
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
SVLEREKLGSTVLGTGIAIPHPLGLMAKETKIVIRILDKPIKWDQKQSVHAVFLLCISKH
HHHHHHHCCCCHHCCCCCCCCCCCCHHHHHHHHHEECCCCCCCCCCCHHHHHHHHHHCCC
DYEEAINIYELLVELVREEYGEKLANLTNFREFTTLAKDILKKK
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
GYFAYKRLETLYGMLLDAGSHLSAQKLSQELHISERTIRTDIAKLTEFLENHGATITLT
CCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEE
RGAGYKIEILDPAAFQAFQNEKNKPKNADYFDLDNPEERVKYEIFLLLSSADYIKLEDLA
CCCCEEEEEECHHHHHHHHCCCCCCCCCCCCCCCCHHHHHEEEEEEEEECCCCEEHHHHH
DTIYASRATISNDMKQVRKVIASYDLTLVSKPGSGVKIVGEEEKMRYTLTALIASKKAPE
HHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCEEEECCCHHHHHHHHHHHHCCCCCH
SYLETFFEWHKQKDKLQKLMSAVTDYFFATNIRFTDEALQNLLLHMMILVERIELGHSLE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEHHHHHHHHHHHHHHHHHHHHHCCCCC
QFELTDVSEEEIVIANKLATILESLFEITISSADKNYLLLQIASKRILNVEDKEISEFDD
CEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEHHHHHCCCCCHHHHHHHH
YAYIEGMLNRIESHYSYHLQDDLQLKKDLIAHIHSMLYRVKYHMTVKNPMTEHIKRYYPL
HHHHHHHHHHHHHHCEECCCHHHHHHHHHHHHHHHHHHHHHHEEEECCHHHHHHHHHCCE
AYEITLDAVESLKKDYPYDINQNELAYLALHIGASLERNYQISYYRHKSALIVCGSGFGT
EEEEEHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCCCCEEEEEEEECCEEEEEECCCCC
ARIVEAKVKSAVSNLDITKVVSIQEYNRFIHIEEDIILSTVRIPEKNKPVIKISNIPTNE
HHHHHHHHHHHHHCCCHHHEEEHHHCCCEEEECHHHEEEEEECCCCCCCEEEECCCCCCH
ELKMLGAIIQEQTDSNRGFLSNFFTAEFFARSELTSKSAILKEMVSSLYKNDIVGTDFLG
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
SVLEREKLGSTVLGTGIAIPHPLGLMAKETKIVIRILDKPIKWDQKQSVHAVFLLCISKH
HHHHHHHCCCCHHCCCCCCCCCCCCHHHHHHHHHEECCCCCCCCCCCHHHHHHHHHHCCC
DYEEAINIYELLVELVREEYGEKLANLTNFREFTTLAKDILKKK
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8990303; 8969509; 9384377; 10438772 [H]