Click here to switch to the map view.

The map label for this gene is inlB [H]

Identifier: 116871729

GI number: 116871729

Start: 331266

End: 333308

Strand: Direct

Name: inlB [H]

Synonym: lwe0309

Alternate gene names: 116871729

Gene position: 331266-333308 (Clockwise)

Preceding gene: 116871728

Following gene: 116871730

Centisome position: 11.77

GC content: 36.27

Gene sequence:

>2043_bases
GTGAAACAACCTCAAAAATTATTTAAATACTTATTTATAATAATGATAATGGGAATTAGTTTATGGATTGGATTAGGGCC
AGAAATGGAAGTTCATGCAGCTACTCTTAACGAAAGTACTCCCATCAATCAACTTTTCCCTGATCCGGTTTTAGCAGAAA
AAATACGATCAACAACAGCCAAGCCAAGTGTAGGTAGTACGGTTACGCAAAGTGACTTAAACAAAGTAACTTATGTAAAT
ATCCAAGGTTATGGGAAAGAACCTATTAAGTCAATTGAAGGAATGCAGTATTTAAATGAACTGAGCTATTTAAGTTTAGA
TGGGAATCAGGTGAGCGATTTAACTCCTCTGGCTAACGCAACTAAGTTAACCTATTTAACATTATCAGATAATAATGTTA
GTGATGTTAGCAGCTTGAAAAATTTAAGTAAAGTATATTTGATTGGTTTAAAAAATAACCAAGTAGAAGATATTAGTTCA
CTTTCAAATTTAACAGCTTTAAAATACCTTTATTTAAATGGTAATAAATTGAGTGATTTAAGTGCTATTGCCAACCTAAC
AACTTTAGATATACTAGAAGTGAAAAATCAACAAGTAACAAAACAATCAGTAGCATTCCAGAATAATCTAGTTTTACCAA
ACACTATTAAAGATACCAAAGGAGCTTCCATTGCGCCTACCAATATTAGTAATAACGGTACTTACAGCAATAACAGCTTG
AATTGGTCTTTACCAGAGTTAACAAATGAAGTAACTTATAGTTTTAGTCAAACTGTGACAGCTGGAAGTAAAATATCGAC
TGAATTTAGTGGAACAGTGACTCAACCTATTCACGAAACTATATATCACACAGCAATATTCGATGTGGATGGTGTACAAA
TAAATGATACAAAAGAAATTAGTACATTAATAGAAGAACCGCCCACTCCAACAAAAGAAGGTTATACTTTTATAGGTTGG
TTTGATGAAGAAGGAAACGAATGGGATTTTTCAACAGACAAAATGCCTGAAAAAGATTTAACTTTATATGCTCGTTTCGA
TAAAGATACAAGTGAAGTGGTGGTTCCAGAAGAAGGAACCGAAACTCCGGCAGAAGAAGTGGAAGTACCAGAAGAAGGAA
CCGAAACTCCGGCAGAAGAAGTGGAAGTACCAGAAGAAGATACGGAAACTCCGGCAGAAGAAGTAGAGGTACCAGAAGAA
GAAACCGAAACTCCGGCAGAAGAAGTAGAGGTACCAGAAGAAGAAACCGAAACTCCGGCAGAAGAAGTGGAAGTACCAGA
AGAAGAAACCGAAACTCCGGCAGAAGAAGTGGAAGTACCAGAAGAAGGAACCGAAACTCCGGCAGAAGAAGTGGAAGTAC
CAGAAGAAGGAACCGAAACTCCGGCAGAAGAAGTGGAAGTACCAGAAGAAGGAACCGAAACTCCGGCAGAAGAAGTAGAA
GTGCCAGAAGAAGATACAGAAACCCCTGCAGAAGAAGTGGAAGTACCAGAAGAAGATACGGAAACTCCATCTGAAGAAGT
GGAAGTACCAGAAGAAGAAACCGAAACTCCGGCAGAAGAAGTAGAGGTACCAGAAGAAGAAATCGAAACTCCAGCCGAAG
AAGTAGAAGTGCCAGAAGAAGAAACCGAAACTCCAGCCGAAGAAGTAGAAGTACCAGAAAAAGACACGGAAACTCCAACT
AAGAAAATGGTAGCTTCCAAACAAGTACAGGAAATATCTGCTGAATCAACGACCCTCATAAAAAATCCTGAAATATTAGA
AACGATTTCAAGTGATGTTGTCGAAGAACCAATTGAAAATAATAAAAAAGCAGTTAAATCTATTAATTTAAATGCTGATT
CAAGCAAATCACAAGAAAATACTAAAGATGACAGTGATTATGAGGAAGTAAAAAGTAATAAAATCGCAGAGAATAAAAAA
GTATCGACACAAACAAGTTCATTTTTACCTATTATAGGCGATAGTCAAAATTTCTGGTTTTCTTTAATGGGAATGATAAT
TATGGCTCTATCACTAGTATTTGGTAGAAAAAAACGTCTTTAA

Upstream 100 bases:

>100_bases
ATATTTTAGGGAGGGTTATTATAGCCCAATACACCGTTTATTTGTGTGTTAGTATAACTTATGTAAGATAAACATGAATC
AAAAAGAAAGGAGACTTCGT

Downstream 100 bases:

>100_bases
GAAAAGATAATGGCAAGAACAGTCTAATATAGTCATACTTAAAAGTTGGAATAAAAAGCTTACTTTTAAGTGATACTATA
TAGAGAGTCTGTTCTTTTTT

Product: internalin family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 680; Mature: 680

Protein sequence:

>680_residues
MKQPQKLFKYLFIIMIMGISLWIGLGPEMEVHAATLNESTPINQLFPDPVLAEKIRSTTAKPSVGSTVTQSDLNKVTYVN
IQGYGKEPIKSIEGMQYLNELSYLSLDGNQVSDLTPLANATKLTYLTLSDNNVSDVSSLKNLSKVYLIGLKNNQVEDISS
LSNLTALKYLYLNGNKLSDLSAIANLTTLDILEVKNQQVTKQSVAFQNNLVLPNTIKDTKGASIAPTNISNNGTYSNNSL
NWSLPELTNEVTYSFSQTVTAGSKISTEFSGTVTQPIHETIYHTAIFDVDGVQINDTKEISTLIEEPPTPTKEGYTFIGW
FDEEGNEWDFSTDKMPEKDLTLYARFDKDTSEVVVPEEGTETPAEEVEVPEEGTETPAEEVEVPEEDTETPAEEVEVPEE
ETETPAEEVEVPEEETETPAEEVEVPEEETETPAEEVEVPEEGTETPAEEVEVPEEGTETPAEEVEVPEEGTETPAEEVE
VPEEDTETPAEEVEVPEEDTETPSEEVEVPEEETETPAEEVEVPEEEIETPAEEVEVPEEETETPAEEVEVPEKDTETPT
KKMVASKQVQEISAESTTLIKNPEILETISSDVVEEPIENNKKAVKSINLNADSSKSQENTKDDSDYEEVKSNKIAENKK
VSTQTSSFLPIIGDSQNFWFSLMGMIIMALSLVFGRKKRL

Sequences:

>Translated_680_residues
MKQPQKLFKYLFIIMIMGISLWIGLGPEMEVHAATLNESTPINQLFPDPVLAEKIRSTTAKPSVGSTVTQSDLNKVTYVN
IQGYGKEPIKSIEGMQYLNELSYLSLDGNQVSDLTPLANATKLTYLTLSDNNVSDVSSLKNLSKVYLIGLKNNQVEDISS
LSNLTALKYLYLNGNKLSDLSAIANLTTLDILEVKNQQVTKQSVAFQNNLVLPNTIKDTKGASIAPTNISNNGTYSNNSL
NWSLPELTNEVTYSFSQTVTAGSKISTEFSGTVTQPIHETIYHTAIFDVDGVQINDTKEISTLIEEPPTPTKEGYTFIGW
FDEEGNEWDFSTDKMPEKDLTLYARFDKDTSEVVVPEEGTETPAEEVEVPEEGTETPAEEVEVPEEDTETPAEEVEVPEE
ETETPAEEVEVPEEETETPAEEVEVPEEETETPAEEVEVPEEGTETPAEEVEVPEEGTETPAEEVEVPEEGTETPAEEVE
VPEEDTETPAEEVEVPEEDTETPSEEVEVPEEETETPAEEVEVPEEEIETPAEEVEVPEEETETPAEEVEVPEKDTETPT
KKMVASKQVQEISAESTTLIKNPEILETISSDVVEEPIENNKKAVKSINLNADSSKSQENTKDDSDYEEVKSNKIAENKK
VSTQTSSFLPIIGDSQNFWFSLMGMIIMALSLVFGRKKRL
>Mature_680_residues
MKQPQKLFKYLFIIMIMGISLWIGLGPEMEVHAATLNESTPINQLFPDPVLAEKIRSTTAKPSVGSTVTQSDLNKVTYVN
IQGYGKEPIKSIEGMQYLNELSYLSLDGNQVSDLTPLANATKLTYLTLSDNNVSDVSSLKNLSKVYLIGLKNNQVEDISS
LSNLTALKYLYLNGNKLSDLSAIANLTTLDILEVKNQQVTKQSVAFQNNLVLPNTIKDTKGASIAPTNISNNGTYSNNSL
NWSLPELTNEVTYSFSQTVTAGSKISTEFSGTVTQPIHETIYHTAIFDVDGVQINDTKEISTLIEEPPTPTKEGYTFIGW
FDEEGNEWDFSTDKMPEKDLTLYARFDKDTSEVVVPEEGTETPAEEVEVPEEGTETPAEEVEVPEEDTETPAEEVEVPEE
ETETPAEEVEVPEEETETPAEEVEVPEEETETPAEEVEVPEEGTETPAEEVEVPEEGTETPAEEVEVPEEGTETPAEEVE
VPEEDTETPAEEVEVPEEDTETPSEEVEVPEEETETPAEEVEVPEEEIETPAEEVEVPEEETETPAEEVEVPEKDTETPT
KKMVASKQVQEISAESTTLIKNPEILETISSDVVEEPIENNKKAVKSINLNADSSKSQENTKDDSDYEEVKSNKIAENKK
VSTQTSSFLPIIGDSQNFWFSLMGMIIMALSLVFGRKKRL

Specific function: Mediates the entry of Listeria monocytogenes into cells [H]

COG id: COG4886

COG function: function code S; Leucine-rich repeat (LRR) protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 7 LRR (leucine-rich) repeats [H]

Homologues:

Organism=Homo sapiens, GI16554449, Length=332, Percent_Identity=21.3855421686747, Blast_Score=86, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014755
- InterPro:   IPR014756
- InterPro:   IPR001611
- InterPro:   IPR013378
- InterPro:   IPR012569 [H]

Pfam domain/function: PF09479 Flg_new; PF00560 LRR_1; PF08191 LRR_adjacent [H]

EC number: NA

Molecular weight: Translated: 75276; Mature: 75276

Theoretical pI: Translated: 3.71; Mature: 3.71

Prosite motif: PS50847 GRAM_POS_ANCHORING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQPQKLFKYLFIIMIMGISLWIGLGPEMEVHAATLNESTPINQLFPDPVLAEKIRSTTA
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHCCCHHHHHHHHHCCC
KPSVGSTVTQSDLNKVTYVNIQGYGKEPIKSIEGMQYLNELSYLSLDGNQVSDLTPLANA
CCCCCCCCCHHCCCEEEEEEEECCCCCHHHHHHHHHHHHHHCEEEECCCCCCCCCCCCCC
TKLTYLTLSDNNVSDVSSLKNLSKVYLIGLKNNQVEDISSLSNLTALKYLYLNGNKLSDL
CEEEEEEECCCCHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHEEEEEEEECCCCCHHH
SAIANLTTLDILEVKNQQVTKQSVAFQNNLVLPNTIKDTKGASIAPTNISNNGTYSNNSL
HHHHHHHHHHHHHHCCHHHHHHHHHHHCCEECCCCCCCCCCCEECCCCCCCCCCCCCCCC
NWSLPELTNEVTYSFSQTVTAGSKISTEFSGTVTQPIHETIYHTAIFDVDGVQINDTKEI
CEECHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHEEECCCEEECCHHHH
STLIEEPPTPTKEGYTFIGWFDEEGNEWDFSTDKMPEKDLTLYARFDKDTSEVVVPEEGT
HHHHHCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCEEEEEECCCCCCEECCCCCC
ETPAEEVEVPEEGTETPAEEVEVPEEDTETPAEEVEVPEEETETPAEEVEVPEEETETPA
CCCHHHCCCCCCCCCCCHHHCCCCCCCCCCCHHHCCCCHHHCCCCHHHCCCCHHHCCCCH
EEVEVPEEETETPAEEVEVPEEGTETPAEEVEVPEEGTETPAEEVEVPEEGTETPAEEVE
HHCCCCHHHCCCCHHHCCCCCCCCCCCHHHCCCCCCCCCCCHHHCCCCCCCCCCCHHHCC
VPEEDTETPAEEVEVPEEDTETPSEEVEVPEEETETPAEEVEVPEEEIETPAEEVEVPEE
CCCCCCCCCHHHCCCCCCCCCCCHHHCCCCHHHCCCCHHHHCCCHHHHCCCHHHCCCCHH
ETETPAEEVEVPEKDTETPTKKMVASKQVQEISAESTTLIKNPEILETISSDVVEEPIEN
HCCCCHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEECCCHHHHHHHHHHHHHHHHC
NKKAVKSINLNADSSKSQENTKDDSDYEEVKSNKIAENKKVSTQTSSFLPIIGDSQNFWF
CCHHHHEECCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCHHHH
SLMGMIIMALSLVFGRKKRL
HHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKQPQKLFKYLFIIMIMGISLWIGLGPEMEVHAATLNESTPINQLFPDPVLAEKIRSTTA
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHCCCHHHHHHHHHCCC
KPSVGSTVTQSDLNKVTYVNIQGYGKEPIKSIEGMQYLNELSYLSLDGNQVSDLTPLANA
CCCCCCCCCHHCCCEEEEEEEECCCCCHHHHHHHHHHHHHHCEEEECCCCCCCCCCCCCC
TKLTYLTLSDNNVSDVSSLKNLSKVYLIGLKNNQVEDISSLSNLTALKYLYLNGNKLSDL
CEEEEEEECCCCHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHEEEEEEEECCCCCHHH
SAIANLTTLDILEVKNQQVTKQSVAFQNNLVLPNTIKDTKGASIAPTNISNNGTYSNNSL
HHHHHHHHHHHHHHCCHHHHHHHHHHHCCEECCCCCCCCCCCEECCCCCCCCCCCCCCCC
NWSLPELTNEVTYSFSQTVTAGSKISTEFSGTVTQPIHETIYHTAIFDVDGVQINDTKEI
CEECHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHEEECCCEEECCHHHH
STLIEEPPTPTKEGYTFIGWFDEEGNEWDFSTDKMPEKDLTLYARFDKDTSEVVVPEEGT
HHHHHCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCEEEEEECCCCCCEECCCCCC
ETPAEEVEVPEEGTETPAEEVEVPEEDTETPAEEVEVPEEETETPAEEVEVPEEETETPA
CCCHHHCCCCCCCCCCCHHHCCCCCCCCCCCHHHCCCCHHHCCCCHHHCCCCHHHCCCCH
EEVEVPEEETETPAEEVEVPEEGTETPAEEVEVPEEGTETPAEEVEVPEEGTETPAEEVE
HHCCCCHHHCCCCHHHCCCCCCCCCCCHHHCCCCCCCCCCCHHHCCCCCCCCCCCHHHCC
VPEEDTETPAEEVEVPEEDTETPSEEVEVPEEETETPAEEVEVPEEEIETPAEEVEVPEE
CCCCCCCCCHHHCCCCCCCCCCCHHHCCCCHHHCCCCHHHHCCCHHHHCCCHHHCCCCHH
ETETPAEEVEVPEKDTETPTKKMVASKQVQEISAESTTLIKNPEILETISSDVVEEPIEN
HCCCCHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEECCCHHHHHHHHHHHHHHHHC
NKKAVKSINLNADSSKSQENTKDDSDYEEVKSNKIAENKKVSTQTSSFLPIIGDSQNFWF
CCHHHHEECCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCHHHH
SLMGMIIMALSLVFGRKKRL
HHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1905979; 11679669; 10635330 [H]