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The map label for this gene is xylA

Identifier: 116871663

GI number: 116871663

Start: 261583

End: 262890

Strand: Direct

Name: xylA

Synonym: lwe0243

Alternate gene names: 116871663

Gene position: 261583-262890 (Clockwise)

Preceding gene: 116871662

Following gene: 116871664

Centisome position: 9.3

GC content: 37.46

Gene sequence:

>1308_bases
ATGACATATTTTAAACAAATTGAAAAAATAAATTATGAAGGTGTACAGTCAGGAAATCGGTTCGCCTTTAGACATTACAA
TCCGGAAGAAGTAGTTTTAGGGAAATCGATGAAGGAACATTTGCGCTTTGCAGTTGCTTATTGGCATACCATGACTCAAG
ATGGATCTGACCCGTTTGGTGCTGCGACGAATGTTCGCGATGTTTCTGGCAAAACAGAAATGGAGCTTGCGCGAAATCGT
GTAGAGATGTTTTTTGAAATTTTAGAGAAGCTTGGCGTGGAATATTTTTGCTTTCATGACGTGGATATTGCGCCAGAAGG
AAATTCTTTGCAAGAGTTTATGCGTAATTTGGATGAAATAACGGATTTAATTCAAGACAAAATGAAACAAACGGGGATTA
AATTGTTATGGAATACGGCGAACCTTTTTACACATCCACGCTTTTTAAATGGTGCTGCTTCGACAAATAATGCAGATGTA
TACGCATTTTCAGCTGCTCAAATTAAAAAGGGACTCGATATTAGTAAAAAATTAGGTGGGAAAAATTATGTTTTTTGGGG
TGGAAGAGAAGGTTATGAATCCCTCCTTAATACAGACATGGAGTTTGAACAAGCGAATATGGCACGAATGTATAAAATGG
CGATTCGTTACGCAAACGAAATTGAACACGAGGTGCAGTTTCTAATTGAGCCGAAGCCAAAAGAACCAACAAAACATCAA
TACGATTTTGATGCCGCTACAACGATGGCTTTTTTACAAAAATACGGTCTTGAAAATGATTTTAAACTAAATTTAGAAGC
GAATCACGCTACACTTGCTGGACACACATTTGAACATGAATTAAATGTGGCTAGAACTTATAATGCACTAGGGTCCATTG
ATGCCAACCAAGGGGACCTGCTTCTAGGCTGGGATACAGATGAATTTCCAACAAATATTTACGATACAACGCTTACTATG
TATGAAATTCTTCAAAATGGCGGTATCGCACCAGGTGGAATTAATTTTGATGCCAAAGTTAGACGTACATCTTTTGAAAT
GGAAGACTTGTTACTGGCGCATATTGCTGGCATGGACACATATGCAAGAGGCTTAAAGGCAGCGGCAAAACTAACAGAAG
ATCACTTTTTTGATAAAATAAAAGAAGAACGGTATAGAAGTTTTAAGAAGGGAATTGGTGCACGCATTTTAGATAATCAG
GAGGATTTTAAATCGCTAACTGAATATGCGTTAGCACATGATTCTATCCAAAACGAATCTAGCCATATCGAATATGTGAA
GTCACGCTTGAACGATTATTTAGTATAA

Upstream 100 bases:

>100_bases
TATTTTTCTATCGTGCAGATAAACAAGAAAAACAATATTTAGTAGAGTTAGAAGAACGAAATCGTACGTTTCGGGAAAAT
GAAAAATAAAGGAGAGTATT

Downstream 100 bases:

>100_bases
AGGAGAAAAAAATGGCTTATGTGTTAGGGTTAGATTTAGGAACAAGCGCACTAAAAGCAGTGTTGATGACTGAAATAGGC
GAATGGATAGCCGAGGCATC

Product: xylose isomerase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 435; Mature: 434

Protein sequence:

>435_residues
MTYFKQIEKINYEGVQSGNRFAFRHYNPEEVVLGKSMKEHLRFAVAYWHTMTQDGSDPFGAATNVRDVSGKTEMELARNR
VEMFFEILEKLGVEYFCFHDVDIAPEGNSLQEFMRNLDEITDLIQDKMKQTGIKLLWNTANLFTHPRFLNGAASTNNADV
YAFSAAQIKKGLDISKKLGGKNYVFWGGREGYESLLNTDMEFEQANMARMYKMAIRYANEIEHEVQFLIEPKPKEPTKHQ
YDFDAATTMAFLQKYGLENDFKLNLEANHATLAGHTFEHELNVARTYNALGSIDANQGDLLLGWDTDEFPTNIYDTTLTM
YEILQNGGIAPGGINFDAKVRRTSFEMEDLLLAHIAGMDTYARGLKAAAKLTEDHFFDKIKEERYRSFKKGIGARILDNQ
EDFKSLTEYALAHDSIQNESSHIEYVKSRLNDYLV

Sequences:

>Translated_435_residues
MTYFKQIEKINYEGVQSGNRFAFRHYNPEEVVLGKSMKEHLRFAVAYWHTMTQDGSDPFGAATNVRDVSGKTEMELARNR
VEMFFEILEKLGVEYFCFHDVDIAPEGNSLQEFMRNLDEITDLIQDKMKQTGIKLLWNTANLFTHPRFLNGAASTNNADV
YAFSAAQIKKGLDISKKLGGKNYVFWGGREGYESLLNTDMEFEQANMARMYKMAIRYANEIEHEVQFLIEPKPKEPTKHQ
YDFDAATTMAFLQKYGLENDFKLNLEANHATLAGHTFEHELNVARTYNALGSIDANQGDLLLGWDTDEFPTNIYDTTLTM
YEILQNGGIAPGGINFDAKVRRTSFEMEDLLLAHIAGMDTYARGLKAAAKLTEDHFFDKIKEERYRSFKKGIGARILDNQ
EDFKSLTEYALAHDSIQNESSHIEYVKSRLNDYLV
>Mature_434_residues
TYFKQIEKINYEGVQSGNRFAFRHYNPEEVVLGKSMKEHLRFAVAYWHTMTQDGSDPFGAATNVRDVSGKTEMELARNRV
EMFFEILEKLGVEYFCFHDVDIAPEGNSLQEFMRNLDEITDLIQDKMKQTGIKLLWNTANLFTHPRFLNGAASTNNADVY
AFSAAQIKKGLDISKKLGGKNYVFWGGREGYESLLNTDMEFEQANMARMYKMAIRYANEIEHEVQFLIEPKPKEPTKHQY
DFDAATTMAFLQKYGLENDFKLNLEANHATLAGHTFEHELNVARTYNALGSIDANQGDLLLGWDTDEFPTNIYDTTLTMY
EILQNGGIAPGGINFDAKVRRTSFEMEDLLLAHIAGMDTYARGLKAAAKLTEDHFFDKIKEERYRSFKKGIGARILDNQE
DFKSLTEYALAHDSIQNESSHIEYVKSRLNDYLV

Specific function: Unknown

COG id: COG2115

COG function: function code G; Xylose isomerase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xylose isomerase family

Homologues:

Organism=Escherichia coli, GI1789988, Length=435, Percent_Identity=47.5862068965517, Blast_Score=442, Evalue=1e-125,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): XYLA_LISW6 (A0AF79)

Other databases:

- EMBL:   AM263198
- RefSeq:   YP_848444.1
- ProteinModelPortal:   A0AF79
- SMR:   A0AF79
- STRING:   A0AF79
- GeneID:   4465819
- GenomeReviews:   AM263198_GR
- KEGG:   lwe:lwe0243
- NMPDR:   fig|386043.6.peg.232
- eggNOG:   COG2115
- HOGENOM:   HBG297199
- OMA:   LLGWDTD
- PhylomeDB:   A0AF79
- ProtClustDB:   PRK05474
- BioCyc:   LWEL386043:LWE0243-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00455
- InterPro:   IPR013022
- InterPro:   IPR012307
- InterPro:   IPR013452
- InterPro:   IPR001998
- Gene3D:   G3DSA:3.20.20.150
- PRINTS:   PR00688
- TIGRFAMs:   TIGR02630

Pfam domain/function: PF01261 AP_endonuc_2; SSF51658 Xyl_isomerase-like_TIM-brl

EC number: =5.3.1.5

Molecular weight: Translated: 49863; Mature: 49731

Theoretical pI: Translated: 5.15; Mature: 5.15

Prosite motif: PS51415 XYLOSE_ISOMERASE; PS00172 XYLOSE_ISOMERASE_1 ; PS00173 XYLOSE_ISOMERASE_2

Important sites: ACT_SITE 99-99 ACT_SITE 102-102

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTYFKQIEKINYEGVQSGNRFAFRHYNPEEVVLGKSMKEHLRFAVAYWHTMTQDGSDPFG
CCHHHHHHHCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
AATNVRDVSGKTEMELARNRVEMFFEILEKLGVEYFCFHDVDIAPEGNSLQEFMRNLDEI
CCCCCHHCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEECCEECCCCCHHHHHHHHHHHH
TDLIQDKMKQTGIKLLWNTANLFTHPRFLNGAASTNNADVYAFSAAQIKKGLDISKKLGG
HHHHHHHHHHCCCEEEEECHHHHCCCHHCCCCCCCCCCCEEEEEHHHHHHCCCHHHHCCC
KNYVFWGGREGYESLLNTDMEFEQANMARMYKMAIRYANEIEHEVQFLIEPKPKEPTKHQ
CCEEEECCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCC
YDFDAATTMAFLQKYGLENDFKLNLEANHATLAGHTFEHELNVARTYNALGSIDANQGDL
CCCHHHHHHHHHHHHCCCCCEEEEEECCCEEECCCCHHHHHHHHHHHHHHCCCCCCCCCE
LLGWDTDEFPTNIYDTTLTMYEILQNGGIAPGGINFDAKVRRTSFEMEDLLLAHIAGMDT
EEECCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHH
YARGLKAAAKLTEDHFFDKIKEERYRSFKKGIGARILDNQEDFKSLTEYALAHDSIQNES
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCHHHHHHHHHHHHHHHHHCCCH
SHIEYVKSRLNDYLV
HHHHHHHHHHHHCCC
>Mature Secondary Structure 
TYFKQIEKINYEGVQSGNRFAFRHYNPEEVVLGKSMKEHLRFAVAYWHTMTQDGSDPFG
CHHHHHHHCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
AATNVRDVSGKTEMELARNRVEMFFEILEKLGVEYFCFHDVDIAPEGNSLQEFMRNLDEI
CCCCCHHCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEECCEECCCCCHHHHHHHHHHHH
TDLIQDKMKQTGIKLLWNTANLFTHPRFLNGAASTNNADVYAFSAAQIKKGLDISKKLGG
HHHHHHHHHHCCCEEEEECHHHHCCCHHCCCCCCCCCCCEEEEEHHHHHHCCCHHHHCCC
KNYVFWGGREGYESLLNTDMEFEQANMARMYKMAIRYANEIEHEVQFLIEPKPKEPTKHQ
CCEEEECCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCC
YDFDAATTMAFLQKYGLENDFKLNLEANHATLAGHTFEHELNVARTYNALGSIDANQGDL
CCCHHHHHHHHHHHHCCCCCEEEEEECCCEEECCCCHHHHHHHHHHHHHHCCCCCCCCCE
LLGWDTDEFPTNIYDTTLTMYEILQNGGIAPGGINFDAKVRRTSFEMEDLLLAHIAGMDT
EEECCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHH
YARGLKAAAKLTEDHFFDKIKEERYRSFKKGIGARILDNQEDFKSLTEYALAHDSIQNES
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCHHHHHHHHHHHHHHHHHCCCH
SHIEYVKSRLNDYLV
HHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA