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The map label for this gene is coaX [H]

Identifier: 116871604

GI number: 116871604

Start: 185466

End: 186245

Strand: Direct

Name: coaX [H]

Synonym: lwe0184

Alternate gene names: 116871604

Gene position: 185466-186245 (Clockwise)

Preceding gene: 116871603

Following gene: 116871605

Centisome position: 6.59

GC content: 38.08

Gene sequence:

>780_bases
ATGATACTTGTAATTGATGTTGGAAATACTAACTGTACTGTCGGAGTTTATGAAAAACAAAAGCTTCTAAAACATTGGCG
CATGACAACAGATCGTCACCGCACATCTGATGAATTAGGGATGACAGTCCTGAACTTTTTTTCGTATGCAAATTTAACTC
CTTCTGATATTCAAGGAATTATCATTTCGTCCGTCGTTCCACCAATTATGCACGCAATGGAAACGATGTGTGTGCGCTAT
TTTAATATTCGGCCATTAATCGTTGGTCCAGGAATAAAAACCGGTTTAAATGTAAAAGTTGATAATCCGCGTGAAATTGG
ATCTGATCGAATCGTAAATGCTGTAGCTGCATCTGAAGAATATGGGACACCGATAATTGTAGTGGATTTTGGGACTGCAA
CTACTTTTTGCTATATCGATGAACTCGGAGCATATCAAGGTGGTGCAATTGCCCCAGGTATCATGATTTCAACAGAAGCA
CTATATAATCGTGCTGCCAAATTACCTCGTGTAGATATTGCTGAATCCAACCAAATTATTGGGAAGTCTACCGTATCATC
CATGCAAGCTGGTATTTTTTACGGTTTTGTTGGACAGTGCGAAGGGATTATTGCAGAAATGAAAAAGCAATCTAATTCCA
ATCCTGTAGTAGTTGCGACAGGCGGTCTCGCTCGGATGATAACCGAAAAATCTTCTGCGGTAGATATTTTAGATCCATTT
TTAACATTAAAAGGTCTAGAGCTTTTATATAGAAGAAATAAACCAACTACAGAAAAATAA

Upstream 100 bases:

>100_bases
GGCTTCCCAGTCTCTTTTTTGAAGCTATATTATTCGGATTTTCAAGTGAAACATGTTATGATACGTTAGAAAAATCTTCT
AAAGGACGGTATGAAAATCT

Downstream 100 bases:

>100_bases
AAGGAGATTTATATAATGAGTGATTATTTAATTAAAGCGCTAGCCTATGATGGCATGGCGCGAGTATATGCAGCAGTAAC
AACCGAAACAATCAAAGAAG

Product: pantothenate kinase

Products: NA

Alternate protein names: PanK-III; Pantothenic acid kinase [H]

Number of amino acids: Translated: 259; Mature: 259

Protein sequence:

>259_residues
MILVIDVGNTNCTVGVYEKQKLLKHWRMTTDRHRTSDELGMTVLNFFSYANLTPSDIQGIIISSVVPPIMHAMETMCVRY
FNIRPLIVGPGIKTGLNVKVDNPREIGSDRIVNAVAASEEYGTPIIVVDFGTATTFCYIDELGAYQGGAIAPGIMISTEA
LYNRAAKLPRVDIAESNQIIGKSTVSSMQAGIFYGFVGQCEGIIAEMKKQSNSNPVVVATGGLARMITEKSSAVDILDPF
LTLKGLELLYRRNKPTTEK

Sequences:

>Translated_259_residues
MILVIDVGNTNCTVGVYEKQKLLKHWRMTTDRHRTSDELGMTVLNFFSYANLTPSDIQGIIISSVVPPIMHAMETMCVRY
FNIRPLIVGPGIKTGLNVKVDNPREIGSDRIVNAVAASEEYGTPIIVVDFGTATTFCYIDELGAYQGGAIAPGIMISTEA
LYNRAAKLPRVDIAESNQIIGKSTVSSMQAGIFYGFVGQCEGIIAEMKKQSNSNPVVVATGGLARMITEKSSAVDILDPF
LTLKGLELLYRRNKPTTEK
>Mature_259_residues
MILVIDVGNTNCTVGVYEKQKLLKHWRMTTDRHRTSDELGMTVLNFFSYANLTPSDIQGIIISSVVPPIMHAMETMCVRY
FNIRPLIVGPGIKTGLNVKVDNPREIGSDRIVNAVAASEEYGTPIIVVDFGTATTFCYIDELGAYQGGAIAPGIMISTEA
LYNRAAKLPRVDIAESNQIIGKSTVSSMQAGIFYGFVGQCEGIIAEMKKQSNSNPVVVATGGLARMITEKSSAVDILDPF
LTLKGLELLYRRNKPTTEK

Specific function: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis [H]

COG id: COG1521

COG function: function code K; Putative transcriptional regulator, homolog of Bvg accessory factor

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type III pantothenate kinase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004619 [H]

Pfam domain/function: PF03309 Bvg_acc_factor [H]

EC number: =2.7.1.33 [H]

Molecular weight: Translated: 28256; Mature: 28256

Theoretical pI: Translated: 7.38; Mature: 7.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILVIDVGNTNCTVGVYEKQKLLKHWRMTTDRHRTSDELGMTVLNFFSYANLTPSDIQGI
CEEEEEECCCCEEEEHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHH
IISSVVPPIMHAMETMCVRYFNIRPLIVGPGIKTGLNVKVDNPREIGSDRIVNAVAASEE
HHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCEEEECCCHHCCCHHHHHHHHCCHH
YGTPIIVVDFGTATTFCYIDELGAYQGGAIAPGIMISTEALYNRAAKLPRVDIAESNQII
CCCCEEEEECCCCEEEEEEEHHCCCCCCCCCCCEEEEHHHHHHHHHCCCCCCCCCCCCCC
GKSTVSSMQAGIFYGFVGQCEGIIAEMKKQSNSNPVVVATGGLARMITEKSSAVDILDPF
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCHHHHHHCCCCCHHHHHHH
LTLKGLELLYRRNKPTTEK
HHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MILVIDVGNTNCTVGVYEKQKLLKHWRMTTDRHRTSDELGMTVLNFFSYANLTPSDIQGI
CEEEEEECCCCEEEEHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHH
IISSVVPPIMHAMETMCVRYFNIRPLIVGPGIKTGLNVKVDNPREIGSDRIVNAVAASEE
HHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCEEEECCCHHCCCHHHHHHHHCCHH
YGTPIIVVDFGTATTFCYIDELGAYQGGAIAPGIMISTEALYNRAAKLPRVDIAESNQII
CCCCEEEEECCCCEEEEEEEHHCCCCCCCCCCCEEEEHHHHHHHHHCCCCCCCCCCCCCC
GKSTVSSMQAGIFYGFVGQCEGIIAEMKKQSNSNPVVVATGGLARMITEKSSAVDILDPF
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCHHHHHHCCCCCHHHHHHH
LTLKGLELLYRRNKPTTEK
HHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11679669 [H]