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The map label for this gene is hslO [H]

Identifier: 116871605

GI number: 116871605

Start: 186261

End: 187145

Strand: Direct

Name: hslO [H]

Synonym: lwe0185

Alternate gene names: 116871605

Gene position: 186261-187145 (Clockwise)

Preceding gene: 116871604

Following gene: 116871606

Centisome position: 6.62

GC content: 40.9

Gene sequence:

>885_bases
ATGAGTGATTATTTAATTAAAGCGCTAGCCTATGATGGCATGGCGCGAGTATATGCAGCAGTAACAACCGAAACAATCAA
AGAAGCGCAAAGAAGACATGATACATGGTCCGTGTCATCCGCTGCACTTGGCAGAACAATGACAGGAACTCTTTTCCTAG
GTGCCATGCAAAAAGAAGACCAAAAAATCACTGTGAAAATTGAAGGTGATGGCCCAATTGGTCCTATCGTGGCGGATAGT
AATGCGCAAGGCCAAATTAGAGGATTTGTAACTAATCCGCACGTTCATTTCAGTGAGCTAAATGAGGCTGGAAAACTAGA
CGTCCGCCGTGGTGTAGGTACATCTGGTATGCTTTCTGTAGTAAAAGATTTAGGCTTTGGCGAAAATTTTACTGGTCAAA
CCCCGATAGTTTCTGGGGAAATTGGTGAAGACTTCACTTATTACCTAGCAACATCTGAACAAGTCAATTCATCAGTTGGT
GTTGGAGTCCTCGTTAATCCAGATGATACGATTGAGGCAGCAGGCGGTTTTATGCTTCAATTACTTCCTGGTGCGACAGA
TGAAATCATTGATGAAATCGAGAAAAATCTTACAGCCTTACCAACAGTTTCAAGAATGATTGAAGCTGGCGAAACACCGG
AGTCCATTTTAGCTAAATTAGCGGGTGGCGAAGATAAACTACAAATCTTAGAAAAAATCCCTGTGTCTTTCGAATGTAAC
TGCTCTAAAGAACGTTTTGGTAGTGCGATTATTTCACTTGGAAAAGATGAGATTCGTTCTATGATAGAAGAAGATCACGG
TGCAGAAGCAGAATGCCATTTTTGCCGTAATACCTACGATTTCTCAGAAGAAGAATTAGAAAAACTATATGAAGAAGCGA
AATAA

Upstream 100 bases:

>100_bases
TGCGGTAGATATTTTAGATCCATTTTTAACATTAAAAGGTCTAGAGCTTTTATATAGAAGAAATAAACCAACTACAGAAA
AATAAAAGGAGATTTATATA

Downstream 100 bases:

>100_bases
TAACGAAGGAGTGCCTAACTGGGTGCTCCTTTTTTTAAAAGTGGTTAAACTTGACAAAACAGGTCGGAATTAATTAAACT
ATATGAAAGACCTAAAAAAG

Product: Hsp33-like chaperonin

Products: NA

Alternate protein names: Heat shock protein 33 homolog; HSP33 [H]

Number of amino acids: Translated: 294; Mature: 293

Protein sequence:

>294_residues
MSDYLIKALAYDGMARVYAAVTTETIKEAQRRHDTWSVSSAALGRTMTGTLFLGAMQKEDQKITVKIEGDGPIGPIVADS
NAQGQIRGFVTNPHVHFSELNEAGKLDVRRGVGTSGMLSVVKDLGFGENFTGQTPIVSGEIGEDFTYYLATSEQVNSSVG
VGVLVNPDDTIEAAGGFMLQLLPGATDEIIDEIEKNLTALPTVSRMIEAGETPESILAKLAGGEDKLQILEKIPVSFECN
CSKERFGSAIISLGKDEIRSMIEEDHGAEAECHFCRNTYDFSEEELEKLYEEAK

Sequences:

>Translated_294_residues
MSDYLIKALAYDGMARVYAAVTTETIKEAQRRHDTWSVSSAALGRTMTGTLFLGAMQKEDQKITVKIEGDGPIGPIVADS
NAQGQIRGFVTNPHVHFSELNEAGKLDVRRGVGTSGMLSVVKDLGFGENFTGQTPIVSGEIGEDFTYYLATSEQVNSSVG
VGVLVNPDDTIEAAGGFMLQLLPGATDEIIDEIEKNLTALPTVSRMIEAGETPESILAKLAGGEDKLQILEKIPVSFECN
CSKERFGSAIISLGKDEIRSMIEEDHGAEAECHFCRNTYDFSEEELEKLYEEAK
>Mature_293_residues
SDYLIKALAYDGMARVYAAVTTETIKEAQRRHDTWSVSSAALGRTMTGTLFLGAMQKEDQKITVKIEGDGPIGPIVADSN
AQGQIRGFVTNPHVHFSELNEAGKLDVRRGVGTSGMLSVVKDLGFGENFTGQTPIVSGEIGEDFTYYLATSEQVNSSVGV
GVLVNPDDTIEAAGGFMLQLLPGATDEIIDEIEKNLTALPTVSRMIEAGETPESILAKLAGGEDKLQILEKIPVSFECNC
SKERFGSAIISLGKDEIRSMIEEDHGAEAECHFCRNTYDFSEEELEKLYEEAK

Specific function: Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress [H]

COG id: COG1281

COG function: function code O; Disulfide bond chaperones of the HSP33 family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HSP33 family [H]

Homologues:

Organism=Escherichia coli, GI87082260, Length=295, Percent_Identity=24.7457627118644, Blast_Score=83, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000397
- InterPro:   IPR016154
- InterPro:   IPR016153 [H]

Pfam domain/function: PF01430 HSP33 [H]

EC number: NA

Molecular weight: Translated: 31883; Mature: 31752

Theoretical pI: Translated: 4.28; Mature: 4.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDYLIKALAYDGMARVYAAVTTETIKEAQRRHDTWSVSSAALGRTMTGTLFLGAMQKED
CCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCHHHHHHEEEECCCCC
QKITVKIEGDGPIGPIVADSNAQGQIRGFVTNPHVHFSELNEAGKLDVRRGVGTSGMLSV
CEEEEEEECCCCCCCEEECCCCCCEEEEEEECCCEEHHHHCCCCCEEHHCCCCCHHHHHH
VKDLGFGENFTGQTPIVSGEIGEDFTYYLATSEQVNSSVGVGVLVNPDDTIEAAGGFMLQ
HHHCCCCCCCCCCCCEEECCCCCCEEEEEEEHHHHCCCCCEEEEECCCCCHHHCCCEEEE
LLPGATDEIIDEIEKNLTALPTVSRMIEAGETPESILAKLAGGEDKLQILEKIPVSFECN
ECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHCCCCEECC
CSKERFGSAIISLGKDEIRSMIEEDHGAEAECHFCRNTYDFSEEELEKLYEEAK
CCHHHHHHHHHHCCHHHHHHHHHHCCCCCCEEHHHCCCCCCCHHHHHHHHHHCC
>Mature Secondary Structure 
SDYLIKALAYDGMARVYAAVTTETIKEAQRRHDTWSVSSAALGRTMTGTLFLGAMQKED
CHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCHHHHHHEEEECCCCC
QKITVKIEGDGPIGPIVADSNAQGQIRGFVTNPHVHFSELNEAGKLDVRRGVGTSGMLSV
CEEEEEEECCCCCCCEEECCCCCCEEEEEEECCCEEHHHHCCCCCEEHHCCCCCHHHHHH
VKDLGFGENFTGQTPIVSGEIGEDFTYYLATSEQVNSSVGVGVLVNPDDTIEAAGGFMLQ
HHHCCCCCCCCCCCCEEECCCCCCEEEEEEEHHHHCCCCCEEEEECCCCCHHHCCCEEEE
LLPGATDEIIDEIEKNLTALPTVSRMIEAGETPESILAKLAGGEDKLQILEKIPVSFECN
ECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHCCCCEECC
CSKERFGSAIISLGKDEIRSMIEEDHGAEAECHFCRNTYDFSEEELEKLYEEAK
CCHHHHHHHHHHCCHHHHHHHHHHCCCCCCEEHHHCCCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11679669 [H]